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Advances In Me Cfs Research And Clinical Care
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Book Synopsis Advances In ME/CFS Research and Clinical Care by : Kenneth J. Friedman
Download or read book Advances In ME/CFS Research and Clinical Care written by Kenneth J. Friedman and published by Frontiers Media SA. This book was released on 2019-11-25 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2015, the Institute of Medicine (USA) issued a report critical of the research effort and clinical care for ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) formerly known as Chronic Fatigue Syndrome (CFS) and Chronic Fatigue Immune Deficiency Syndrome (CFIDS). While worldwide investigation into the cause and nature of ME/CFS remains disproportionately small, and treatment remains symptomatic and controversial, modest research continues in all aspects of this disease: epidemiology, possible infectious origins and other triggers, possible involvement of genetics, metabolism, and microbiome, influence of co-morbid conditions, and more. Treatment of patients consists of providing symptomatic relief. Guidance in doing so is provided for the clinician. School-age children require not only treatment but, as revealed in a 25-year retrospective study, continued engagement with peers and social activity. This e-book explores the breadth and depth of current ME/CFS research and clinical care. Its impact for other chronic, complex illnesses should not be overlooked.
Book Synopsis Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by : Institute of Medicine
Download or read book Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are serious, debilitating conditions that affect millions of people in the United States and around the world. ME/CFS can cause significant impairment and disability. Despite substantial efforts by researchers to better understand ME/CFS, there is no known cause or effective treatment. Diagnosing the disease remains a challenge, and patients often struggle with their illness for years before an identification is made. Some health care providers have been skeptical about the serious physiological - rather than psychological - nature of the illness. Once diagnosed, patients often complain of receiving hostility from their health care provider as well as being subjected to treatment strategies that exacerbate their symptoms. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome proposes new diagnostic clinical criteria for ME/CFS and a new term for the illness - systemic exertion intolerance disease(SEID). According to this report, the term myalgic encephalomyelitis does not accurately describe this illness, and the term chronic fatigue syndrome can result in trivialization and stigmatization for patients afflicted with this illness. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome stresses that SEID is a medical - not a psychiatric or psychological - illness. This report lists the major symptoms of SEID and recommends a diagnostic process.One of the report's most important conclusions is that a thorough history, physical examination, and targeted work-up are necessary and often sufficient for diagnosis. The new criteria will allow a large percentage of undiagnosed patients to receive an accurate diagnosis and appropriate care. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome will be a valuable resource to promote the prompt diagnosis of patients with this complex, multisystem, and often devastating disorder; enhance public understanding; and provide a firm foundation for future improvements in diagnosis and treatment.
Book Synopsis Biomedical Insights that Inform the Diagnosis of ME/CFS by : Brett A. Lidbury
Download or read book Biomedical Insights that Inform the Diagnosis of ME/CFS written by Brett A. Lidbury and published by MDPI. This book was released on 2020-03-16 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe chronic health condition that is often misunderstood or ignored by health establishments. The lack of definitive diagnostic markers to separate ME/CFS patients from the healthy population as well as from other chronic disorders is problematic for both health professionals and researchers. A consortium of Australian researchers gathered to systematically understand ME/CFS, ranging from a deep analysis of clinical and pathology data to metabolomic profiles and the investigation of mitochondrial function. From this broad collaboration, a number of compelling insights have arisen that may form the basis of specific serum, blood, and/or urinary biomarkers of ME/CFS. This Special Edition reports on a conference centred on these biomedical discoveries, with other contributions, with a translation focus for predictive markers for ME/CFS diagnosis. By supporting health professionals with developments in diagnostics for this condition, the patients and their families will hopefully benefit from an improved recognition of the biomedical underpinnings of the condition and will be better able to access the care that is urgently required. This Special Edition contains a mix of speaker submissions and other accepted manuscripts that contributed to our objective of advancing biomedical insights to enable the accurate diagnosis of ME/CFS.
Book Synopsis Myalgic Encephalomyelitis / Chronic Fatigue Syndrome by :
Download or read book Myalgic Encephalomyelitis / Chronic Fatigue Syndrome written by and published by CRC Press. This book was released on 2003-02-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important medical milestone for anyone connected with ME/CFS! Myalgic Encephalomyelitis / Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols includes a clinical definition (clinical diagnostic criteria) for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The clinical case definition was developed by an expert medical consensus panel of treating physicians, teaching faculty and world leaders in the research of ME/CFS. An expert subcommittee of Health Canada established the Terms of Reference for the consensus panel. The definition more adequately reflects the complexity of symptoms of a given patient’s pathogenesis and should establish ME/CFS as a distinct medical entity and help distinguish it from overlapping medical conditions in the absence of a definitive laboratory test. “The clinical definition will enable clinicians to make an early diagnosis which may assist in lessening the impact of ME/CFS in some patients,” said Dr. Bruce M. Carruthers, lead author of the definition. “It will reduce the expensive problem of patients being sent to many specialists before being diagnosed and will allow patients to receive appropriate treatments in a timely fashion.” The panel's clinical case definition determines that more of the prominent symptoms are compulsory and symptoms that share a common region of pathogenesis are grouped together for clarity. In addition to severe prolonged fatigue, the definition includes the hallmark symptoms of post-exertional malaise and/or fatigue, sleep dysfunction, pain, two or more of the given neurological/cognitive manifestations, and at least one of the given symptoms from two of the categories of autonomic, neuroendocrine, and immune manifestations. Diagnostic exclusions and common co-morbid entities are also given. The special issue of the Journal of Chronic Fatigue Syndrome also includes a discussion of prominent symptoms, clinical practice diagnostic and treatment guidelines based on the best available research evidence, and an overview of available research on ME/CFS. The expert panel of 11 physicians—who have diagnosed and/or treated more than 20,000 ME/CFS patients between them—has developed a clinical case definition that provides a flexible conceptual framework based on the characteristic patterns of symptom clusters, which reflect specific areas of pathogenesis. The expert subcommittee of Health Canada selected the expert consensus panel. Authors include: Dr. Bruce M. Carruthers, lead author of the consensus document; co-author of the draft of the original version of the ME/CFS clinical definition, diagnostic and treatment protocols document; internal medicine, Galiano, British Columbia. Dr. Anil Kumar Jain, co-author of the draft the original version of the ME/CFS consensus document, affiliate of Ottawa Hospital, Ontario. Dr. Kenny L. De Meirleir, Professor Physiology and Medicine, Vrije Universiteit Brussel, Brussels, Belgium; ME/CFS researcher and clinician; organizer of the World Congress on Chronic Fatigue Syndrome and Related Disorders; a board member of the American Association for Chronic Fatigue Syndrome; and co-editor of Chronic Fatigue Syndrome: Critical Reviews and Clinical Advances (Haworth) Dr. Daniel L. Peterson, affiliate of the Sierra Internal Medicine Associates in Incline Village, Nevada; ME/CFS researcher and clinician; a board member of the American Association for Chronic Fatigue Syndrome; and member of the International Chronic Fatigue Syndrome Study Group Dr. Nancy G. Klimas, Clinical Professor of Medicine in Microbiology/Immunology/Allergy and Psychology, University of Miami School of Medicine; ME/CFS researcher and clinician; a board member of the American Association for Chronic Fatigue Syndrome; and member of the federal CFS Coordinating Committee Dr. A. Martin Lerner, staff physician at William Beaumont Hospital in Royal Oak, Michigan; Clinical professor and former chief of the Division of Infectious Diseases at Wayne State University's School of Medicine; and ME/CFS researcher and clinician Dr. Alison C. Bested, haematological pathologist; former head of the Division of Haematology and Immunology at the Toronto East General and Orthopaedic Hospital; affiliate of the Environmental Health Clinic and Sunnybrook & Women's College Health Sciences Centre, Toronto, Ontario; ME/CFS researcher and clinician Dr. Pierre Flor-Henry, Clinical Professor of Psychiatry, University of Alberta; Clinical Director of General Psychiatry and Director of the Clinical Diagnostic and Research Centre, both based at Alberta Hospital in Edmonton, Alberta, Canada; ME/CFS brain researcher Dr. Pradip Joshi, internal medicine, Clinical Associate Professor of Medicine at Memorial University of Newfoundland in St. John's, Canada Dr. A. C. Peter Powles, Professor Emeritus, Faculty of Health Science, McMasters University, Hamilton; Professor, Faculty of Medicine, University of Toronto; Chief of Medicine and Sleep Disorders Consultant, St. Joseph's Health Centre, Toronto; Sleep Disorder Consultant at the Sleep Disorder Clinic at St. Joseph's Healthcare, Hamilton, and Central West Sleep Affiliation, Paris, Ontario Dr. Jeffrey A. Sherkey, family medicine, affiliate of the University Health Network, Toronto, Ontario; and diagnosed with chronic fatigue syndrome nearly 10 years ago Marjorie I. van de Sande, Consensus Coordinator; and Director of Education for the National ME/FM Action Network, Canada Myalgic Encephalomyelitis / Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols also addresses diagnostic exclusions and common co-morbid entities. This groundbreaking book is must reading for anyone connected with the disease—personally or professionally.
Book Synopsis Pediatric Chronic Fatigue Syndrome by : Kenny De Meirleir
Download or read book Pediatric Chronic Fatigue Syndrome written by Kenny De Meirleir and published by CRC Press. This book was released on 2007-02-07 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Help young CFS sufferers cope with this debilitating illness Chronic Fatigue Syndrome (CFS) is a debilitating illness that can have devastating effects for those afflicted, especially children and adolescents. Pediatric Chronic Fatigue Syndrome discusses this growing problem and its many facets in depth, including the mounting prevalence of incidents in the population and detailed explanations of diagnostic criteria. Case studies are provided to illustrate the issues those afflicted with CFS face, such as increasing isolation, decreasing school attendance, the length of time it typically takes to get diagnosed, and the impact on leisure activities. Current criteria for CFS were designed for use in adults, with few studies done on assessing how appropriate these criteria are for children and adolescents. Pediatric Chronic Fatigue Syndrome provides the criteria for first-time diagnosis of pediatric CFS and includes practical recommendations developed by the International Association of Chronic Fatigue Syndrome Pediatric Case Definition Working Group. This book closely examines the potential impact that Chronic Fatigue Syndrome has on child and adolescent functioning, psychological factors, social factors, and the suffering endured from symptoms. Guidelines are provided on ways ME-CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) can be addressed in primary practice. Topics in Pediatric Chronic Fatigue Syndrome include: ME/CFS CACFS (Chronic Fatigues Syndrome in Children and Adolescents) the common problem of Munchausen-by-proxy research on the psychosocial, family, and physical functioning comparing children and adolescents with CFS and those without CFS using theory in clinical practice guidelines on how ME/CFS can be addressed in primary practice overview of CFS aspects for healthcare professionals who may be called on to diagnose or treat the illness and more Pediatric Chronic Fatigue Syndrome is timely, important information for health professionals, researchers, counselors, caregivers, parents of children and adolescents with CFS, and patients with CFS.
Book Synopsis Chronic Fatigue Syndrome by : Patrick Englebienne
Download or read book Chronic Fatigue Syndrome written by Patrick Englebienne and published by CRC Press. This book was released on 2002-02-27 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Fatigue Syndrome (CFS) is a complex, debilitating disorder, yet few current scientific biomedical books are available on the subject. The nonspecific symptoms, lack of diagnostic tests, and uncertainty as to the cause or causes of CFS make the disease that much more baffling. Chronic Fatigue Syndrome: A Biological Approach represents a monu
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309439124 Total Pages :171 pages Book Rating :4.3/5 (94 download)
Book Synopsis Ending Discrimination Against People with Mental and Substance Use Disorders by : National Academies of Sciences, Engineering, and Medicine
Download or read book Ending Discrimination Against People with Mental and Substance Use Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-09-03 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estimates indicate that as many as 1 in 4 Americans will experience a mental health problem or will misuse alcohol or drugs in their lifetimes. These disorders are among the most highly stigmatized health conditions in the United States, and they remain barriers to full participation in society in areas as basic as education, housing, and employment. Improving the lives of people with mental health and substance abuse disorders has been a priority in the United States for more than 50 years. The Community Mental Health Act of 1963 is considered a major turning point in America's efforts to improve behavioral healthcare. It ushered in an era of optimism and hope and laid the groundwork for the consumer movement and new models of recovery. The consumer movement gave voice to people with mental and substance use disorders and brought their perspectives and experience into national discussions about mental health. However over the same 50-year period, positive change in American public attitudes and beliefs about mental and substance use disorders has lagged behind these advances. Stigma is a complex social phenomenon based on a relationship between an attribute and a stereotype that assigns undesirable labels, qualities, and behaviors to a person with that attribute. Labeled individuals are then socially devalued, which leads to inequality and discrimination. This report contributes to national efforts to understand and change attitudes, beliefs and behaviors that can lead to stigma and discrimination. Changing stigma in a lasting way will require coordinated efforts, which are based on the best possible evidence, supported at the national level with multiyear funding, and planned and implemented by an effective coalition of representative stakeholders. Ending Discrimination Against People with Mental and Substance Use Disorders: The Evidence for Stigma Change explores stigma and discrimination faced by individuals with mental or substance use disorders and recommends effective strategies for reducing stigma and encouraging people to seek treatment and other supportive services. It offers a set of conclusions and recommendations about successful stigma change strategies and the research needed to inform and evaluate these efforts in the United States.
Book Synopsis Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis by : Sarah Myhill
Download or read book Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis written by Sarah Myhill and published by Chelsea Green Publishing. This book was released on 2018 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Original edition published in 2017 by Hammersmith Books, London, United Kingdom"--T.p. verso.
Book Synopsis ME/CFS/PVFS by : Dr. Charles Shepherd
Download or read book ME/CFS/PVFS written by Dr. Charles Shepherd and published by . This book was released on 2018 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis It's All in Your Head by : Suzanne O'Sullivan
Download or read book It's All in Your Head written by Suzanne O'Sullivan and published by Random House. This book was released on 2016 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: A neurologist explores the very real world of psychosomatic illness. Most of us accept the way our heart flutters when we set eyes on the one we secretly admire, or the sweat on our brow as we start the presentation we do not want to give. But few of us are fully aware of how dramatic our body's reactions to emotions can sometimes be. Take Pauline, who first became ill when she was fifteen. What seemed at first to be a urinary infection became joint pain, then food intolerances, then life-threatening appendicitis. And then one day, after a routine operation, Pauline lost all the strength in her legs. Shortly after that her convulsions started. But Pauline's tests are normal; her symptoms seem to have no physical cause whatsoever. Pauline may be an extreme case, but she is by no means alone. As many as a third of men and women visiting their GP have symptoms that are medically unexplained. In most, an emotional root is suspected and yet, when it comes to a diagnosis, this is the very last thing we want to hear, and the last thing doctors want to say. In It's All in Your Head consultant neurologist Dr Suzanne O'Sullivan takes us on a journey through the very real world of psychosomatic illness. She takes us from the extreme -- from paralysis, seizures and blindness -- to more everyday problems such as tiredness and pain. Meeting her patients, she encourages us to look deep inside the human condition. There we find the secrets we are all capable of keeping from ourselves, and our age-old failure to credit the intimate and extraordinary connection between mind and body.
Book Synopsis Chronic Fatigue Syndrome Treatment by : Erica F. Verrillo
Download or read book Chronic Fatigue Syndrome Treatment written by Erica F. Verrillo and published by Macmillan. This book was released on 1998-02-15 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining a self-help manual, personal histories of chronic fatigue sufferers and a dictionary of symptoms and treatments, this comprehensive volume details every facet of the disease and thoroughly discusses every treatment currently available--from diagnosis to symptoms to traditional and alternative therapies to support groups.
Book Synopsis Ferri's Clinical Advisor 2020 E-Book by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2020 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2019-06-01 with total page 7615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri's Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today's medical practice. - Contains significant updates throughout, covering all aspects of current diagnosis and treatment. - Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. - Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. - Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. - Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.
Book Synopsis Fibromyalgia and Chronic Fatigue Syndrome by : Fred Friedberg
Download or read book Fibromyalgia and Chronic Fatigue Syndrome written by Fred Friedberg and published by ReadHowYouWant.com. This book was released on 2010-05 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lifestyle Balance Program for Less Pain and More Energy If you're struggling with fibromyalgia or CFS, this book can help you. It offers an evidence-based improvement program that can help you achieve a healthy balance between activity, rest, and leisure-a balance that can significantly reduce pain and fatigue and increase your energy. In this book, author Fred Friedberg, a clinical psychologist and a leading researcher in chronic fatigue, first explains how lifestyle impacts the severity and persistence of fibromyalgia and CFS. He then goes on to show how the seven step lifestyle balance program can help you to function and feel better. In step one, you'll learn how to use active relaxation techniques to lessen ongoing stress. Better sleep, anger management, and activity pacing make up steps two, three, and four. Step five focuses on overcoming worry and guilt, and you'll learn how low-effort pleasurable activities can ease pain and fatigue in step six. Finally, in step seven, the importance of finding and maintaining personal support is covered. This effective lifestyle-focused program has brought relief to many others like you who have struggled with these misunderstood illnesses-illnesses that modern medicine cannot cure. You can start on the path to a better quality of life today!
Book Synopsis Understanding and Treating Chronic Fatigue by : Joel L. Young
Download or read book Understanding and Treating Chronic Fatigue written by Joel L. Young and published by Bloomsbury Publishing USA. This book was released on 2020-08-19 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some doctors still think Chronic Fatigue Syndrome is a "fake" diagnosis. In this book, Joel Young, MD, presents the research, experience, and treatments that prove otherwise. Millions of Americans experience chronic fatigue syndrome (CFS), a continuous exhaustion and a feeling comparable to that of having just run a marathon when all they have done is a daily living task, such as taking a shower or getting dressed. Doctors don't have tests for CFS, and some think it's a faux or psychological disorder. Joel Young, MD, in this heavily researched book, explains why it is a true physical illness and how it may be treated. He details how he successfully treats the symptoms, which can include severe fatigue, "brain fog," chronic pain, and sleep problems. Unlike doctors who recommend exercise, supplements, or opioid medications, Young integrates such options as long-acting stimulants, meditation, and dietary changes to reduce fatigue, as well as non-opioid drugs, medical marijuana, and self-help options including yoga for the associated chronic pain.
Download or read book Bad Science written by Ben Goldacre and published by Farrar, Straus and Giroux. This book was released on 2010-10-12 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you ever wondered how one day the media can assert that alcohol is bad for us and the next unashamedly run a story touting the benefits of daily alcohol consumption? Or how a drug that is pulled off the market for causing heart attacks ever got approved in the first place? How can average readers, who aren't medical doctors or Ph.D.s in biochemistry, tell what they should be paying attention to and what's, well, just more bullshit? Ben Goldacre has made a point of exposing quack doctors and nutritionists, bogus credentialing programs, and biased scientific studies. He has also taken the media to task for its willingness to throw facts and proof out the window. But he's not here just to tell you what's wrong. Goldacre is here to teach you how to evaluate placebo effects, double-blind studies, and sample sizes, so that you can recognize bad science when you see it. You're about to feel a whole lot better.
Book Synopsis Through the Shadowlands by : Julie Rehmeyer
Download or read book Through the Shadowlands written by Julie Rehmeyer and published by Rodale Books. This book was released on 2017-05-23 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Julie Rehmeyer felt like she was going to the desert to die. Julie fully expected to be breathing at the end of the trip—but driving into Death Valley felt like giving up, surrendering. She’d spent years battling a mysterious illness so extreme that she often couldn’t turn over in her bed. The top specialists in the world were powerless to help, and research on her disease, chronic fatigue syndrome, was at a near standstill. Having exhausted the plausible ideas, Julie turned to an implausible one. Going against both her instincts and her training as a science journalist and mathematician, she followed the advice of strangers she’d met on the Internet. Their theory—that mold in her home and possessions was making her sick—struck her as wacky pseudoscience. But they had recovered from chronic fatigue syndrome as severe as hers. To test the theory that toxic mold was making her sick, Julie drove into the desert alone, leaving behind everything she owned. She wasn’t even certain she was well enough to take care of herself once she was there. She felt stripped not only of the life she’d known, but any future she could imagine. With only her scientific savvy, investigative journalism skills, and dog, Frances, to rely on, Julie carved out her own path to wellness—and uncovered how shocking scientific neglect and misconduct had forced her and millions of others to go it alone. In stunning prose, she describes how her illness transformed her understanding of science, medicine, and spirituality. Through the Shadowlands brings scientific authority to a misunderstood disease and spins an incredible and compelling story of tenacity, resourcefulness, acceptance, and love.
Download or read book The Puzzle Solver written by Tracie White and published by Legacy Lit. This book was released on 2021-01-05 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Father, His Son, and an Unrelenting Quest for a Cure At the age of twenty-seven, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. Finally, even the sound of a footstep in his room became unbearable. The Puzzle Solver follows several years in which he desperately sought answers from specialist after specialist, where at one point his 6'3" frame dropped to 115 lbs. For years, he underwent endless medical tests, but doctors told him there was nothing wrong. Then, finally, a diagnosis: Chronic Fatigue Syndrome, also known as myalgic encephalomyelitis. In the 80s, when an outbreak of people immobilized by an indescribable fatigue were reported near Lake Tahoe, Nevada, doctors were at a loss to explain the symptoms. The condition would alternatively be nicknamed Raggedy Ann Syndrome or the Yuppie Disease, and there was no cure or answers about treatment. They were to remain sick. But there was one answer: Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition. In The Puzzle Solver, journalist Tracie White, who first wrote a viral and award-winning piece on Davis and his family in Stanford Medicine, tells his story. In gripping prose, she masterfully takes readers along on this journey with Davis to solve one of the greatest mysteries in medicine. In a piercing investigative narrative, closed doors are opened, and masked truths are exposed as Davis uncovers new proof confirming that Chronic Fatigue Syndrome is a biological disease. At the heart of this book is a moving story that goes far beyond medicine, this is a story about how the power of love -- and science -- can shine light in even the darkest, most hidden, corners of the world.