Advances In Brain Vascular Research

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Advances in Brain Vascular Research

Author : Ana Clara Cristóvão
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527557235
Total Pages : 202 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis Advances in Brain Vascular Research by : Ana Clara Cristóvão

Download or read book Advances in Brain Vascular Research written by Ana Clara Cristóvão and published by Cambridge Scholars Publishing. This book was released on 2020-07-24 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain vasculature nurtures and regulates basic functions of the central nervous system (CNS), acting as a barrier against pathogens. This book provides in-depth and focused data on the characteristics, function and role of brain blood vessels in health and disease. It addresses topics such as vascular activity, cell-cell communication, and the role of the endothelium in the development of the most prevalent types of cerebrovascular disease, neurodegenerative disorders, cognitive impairment, and vascular abnormalities. It offers an updated view of the current state of microvascular biology and research, and thus supports the discovery of new therapeutic agents and procedures directed at several CNS disorders.

The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
ISBN 13 : 1615047239
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Cerebral Small Vessel Disease

Author : Leonardo Pantoni
Publisher : Cambridge University Press
ISBN 13 : 1107031664
Total Pages : 375 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni

Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

Alzheimer’s Turning Point

Author : Jack C. de la Torre
Publisher : Springer
ISBN 13 : 3319340573
Total Pages : 256 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Alzheimer’s Turning Point by : Jack C. de la Torre

Download or read book Alzheimer’s Turning Point written by Jack C. de la Torre and published by Springer. This book was released on 2016-06-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.

Preventing Cognitive Decline and Dementia

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459591
Total Pages : 181 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Preventing Cognitive Decline and Dementia by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Clinical Bioinformatics

Author : Ronald Trent
Publisher : Humana
ISBN 13 : 9781493947003
Total Pages : 0 pages
Book Rating : 4.9/5 (47 download)

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Book Synopsis Clinical Bioinformatics by : Ronald Trent

Download or read book Clinical Bioinformatics written by Ronald Trent and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.

The Behavioral and Cognitive Neurology of Stroke

Author : Olivier Godefroy
Publisher : Cambridge University Press
ISBN 13 : 1139461893
Total Pages : 637 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Behavioral and Cognitive Neurology of Stroke by : Olivier Godefroy

Download or read book The Behavioral and Cognitive Neurology of Stroke written by Olivier Godefroy and published by Cambridge University Press. This book was released on 2007-01-18 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: The care of stroke patients has changed dramatically. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioural and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management and the likelihood and significance of long-term disability. This book will appeal to all clinicians involved in the care of stroke patients, as well as to neuropsychologists, other rehabilitation therapists and research scientists investigating the underlying neuroscience.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Introduction to Vascular Neurosurgery

Author : Justin R. Mascitelli
Publisher : Springer Nature
ISBN 13 : 3030881962
Total Pages : 550 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Introduction to Vascular Neurosurgery by : Justin R. Mascitelli

Download or read book Introduction to Vascular Neurosurgery written by Justin R. Mascitelli and published by Springer Nature. This book was released on 2022-01-12 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to cover the majority of neurovascular diseases and management. The first section reviews neurovascular anatomy, the basics of angiography, and the basics of craniotomies for neurovascular diseases. Next, an entire section is devoted to intracranial aneurysms, covering the natural history, subarachnoid hemorrhage, endovascular management, microsurgical management, and vasospasm. Following this, a number of chapters are devoted to stroke including natural history, mechanical thrombectomy, intracranial stenosis, Moyamoya disease, bypass surgery, vertebrobasilar insufficiency, intracerebral hemorrhage, sinus thrombosis, and the surgical and endovascular management of extracranial carotid disease. Next, the text covers vascular malformations including arteriovenous malformation, arteriovenous fistulas, carotid cavernous fistulas, vein of Galen malformations, spinal malformations, and cavernous malformations. Finally, the book discusses a few miscellaneous topics including more recent advances in neurovascular care such as venous sinus stenting for idiopathic intracranial hypertension and middle meningeal artery embolization for subdural hematoma. Written by experts in the field, Introduction to Vascular Neurosurgery provides a comprehensive summary of neurovascular disease and management. The book can be used as a daily reference and serves as a trusted resource for medical students, residents, fellows, and young attendings.

Vascular Development

Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 0470319429
Total Pages : 260 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Vascular Development by : Derek J. Chadwick

Download or read book Vascular Development written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

The Blood Brain Barrier (BBB)

Author : Gert Fricker
Publisher : Springer
ISBN 13 : 3662437872
Total Pages : 169 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis The Blood Brain Barrier (BBB) by : Gert Fricker

Download or read book The Blood Brain Barrier (BBB) written by Gert Fricker and published by Springer. This book was released on 2014-10-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Limbic-predominant Age-related TDP-43 Encephalopathy

Author : Beller Health
Publisher : Independently Published
ISBN 13 : 9781097268511
Total Pages : 114 pages
Book Rating : 4.2/5 (685 download)

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Book Synopsis Limbic-predominant Age-related TDP-43 Encephalopathy by : Beller Health

Download or read book Limbic-predominant Age-related TDP-43 Encephalopathy written by Beller Health and published by Independently Published. This book was released on 2019-05-13 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book 9 focuses on a new dementia type, LATE, mistaken as Alzheimer's disease until now.LATE stands for Limbic-predominant age-related TDP-43 encephalopathy, the protein buildup responsible for this dementia. This book is organic, like the series, meaning we never consider our books as finished. Science evolves, which is why our books go through continuous updates. Since LATE is a new dementia classification, we expect continuous further information to emerge. Watch Amazon alerts for potential digital updates. We provide free digital copies on all paperback purchases, so everybody receives free updates.

Oxford Textbook of Cognitive Neurology and Dementia

Author : Masud Husain
Publisher : Oxford University Press
ISBN 13 : 0198831080
Total Pages : 513 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Cognitive Neurology and Dementia by : Masud Husain

Download or read book Oxford Textbook of Cognitive Neurology and Dementia written by Masud Husain and published by Oxford University Press. This book was released on 2018-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.

Advanced Cardiovascular Exercise Physiology

Author : Denise L. Smith
Publisher : Human Kinetics
ISBN 13 : 0736073922
Total Pages : 242 pages
Book Rating : 4.7/5 (36 download)

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Book Synopsis Advanced Cardiovascular Exercise Physiology by : Denise L. Smith

Download or read book Advanced Cardiovascular Exercise Physiology written by Denise L. Smith and published by Human Kinetics. This book was released on 2011 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Cardiovascular Exercise Physiology details the effect of acute and chronic exercise training on each component of the cardiovascular system and how those components adapt to and benefit from a systematic program of exercise training.

Vascular Challenges in Skull Base Surgery

Author : Paul A. Gardner
Publisher : Thieme
ISBN 13 : 1638536465
Total Pages : 569 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Vascular Challenges in Skull Base Surgery by : Paul A. Gardner

Download or read book Vascular Challenges in Skull Base Surgery written by Paul A. Gardner and published by Thieme. This book was released on 2021-11-17 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential multidisciplinary guide for the prevention and management of vascular injury from master skull base surgeons Vascular injury is the most significant source of morbidity or mortality during skull base surgery, regardless of the surgical approach. While skull base approaches always placed arteries and veins at risk, newer endoscopic endonasal approaches have introduced new challenges for the prevention and management of vascular injury. Greater anatomic knowledge, additional surgical options, improved instrumentation, advances in interventional neuroradiology, and enhanced training all contribute to successful outcomes. Vascular Challenges in Skull Base Surgery by renowned skull base experts Paul Gardner, Carl Snyderman, Brian Jankowitz, and distinguished contributors, fills a gap in the literature, with invaluable guidance on managing rare but potentially catastrophic surgical complications. The full range of surgical approaches to the anterior, middle, and posterior cranial fossae are covered in 22 chapters. Diverse topics encompass open and endoscopic endonasal surgical approaches, endovascular techniques including balloon test occlusion and embolization, and standard and alternative bypass procedures. The last three chapters discuss venous considerations, neurophysiologic monitoring, and the role of training and simulation in vascular injury prevention. Key learning points, illustrated discussion of relevant anatomy, and tips and tricks are targeted at helping skull base surgeons leverage practical strategies to improve patient outcomes. Key Highlights An impressive group of expert, highly-experienced surgeons share firsthand knowledge Insightful analyses of root causes and clinical pearls provide indispensable prevention tactics High-quality images and videos enhance visual understanding of surgical anatomy and techniques Trainees and practicing skull base surgeons will greatly benefit from the collective knowledge and evidence-based injury avoidance strategies shared by authors who have learned to master the art of skull base surgery.

Medical Imaging Physics

Author : William R. Hendee
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 548 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Imaging Physics by : William R. Hendee

Download or read book Medical Imaging Physics written by William R. Hendee and published by Wiley-Liss. This book was released on 2002 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: William Hendee and Russell Ritenour's comprehensive text provides the tools necessary to be comfortable with the physical principles, technology concepts, equiment, and procedures used in diagnostic imaging, as well as to appreciate the technological capabilities and limitations of the discipline. Readers need not possess a background in physics. Broadly accessible, Medical Imaging Physics covers all aspects of image formation in modern medical imaging modalities, such as radiography, ultrasonography, computed tomopgraphy(CT), nuclear imaging, and magnetic resonance. Other topics covered include; Digital x-ray imaging Doppler ultrasound Helical CT scanning Accumulation and analysis of nuclear data Experimental radiobiology Radiation protection and safety