Advanced Therapy For Hepatitis C

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Eliminating the Public Health Problem of Hepatitis B and C in the United States

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309438020
Total Pages : 187 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Eliminating the Public Health Problem of Hepatitis B and C in the United States by : National Academies of Sciences, Engineering, and Medicine

Download or read book Eliminating the Public Health Problem of Hepatitis B and C in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-06-01 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Chronic Hepatitis C Virus

Author : Mitchell L. Shiffman
Publisher : Springer Science & Business Media
ISBN 13 : 1461411920
Total Pages : 333 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Chronic Hepatitis C Virus by : Mitchell L. Shiffman

Download or read book Chronic Hepatitis C Virus written by Mitchell L. Shiffman and published by Springer Science & Business Media. This book was released on 2011-11-17 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

A National Strategy for the Elimination of Hepatitis B and C

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309457297
Total Pages : 297 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis A National Strategy for the Elimination of Hepatitis B and C by : National Academies of Sciences, Engineering, and Medicine

Download or read book A National Strategy for the Elimination of Hepatitis B and C written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-30 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.

Liver Transplantation

Author : James Neuberger
Publisher : John Wiley & Sons
ISBN 13 : 1119633990
Total Pages : 592 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Liver Transplantation by : James Neuberger

Download or read book Liver Transplantation written by James Neuberger and published by John Wiley & Sons. This book was released on 2021-02-25 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.

Guidelines on Hepatitis B and C Testing

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9789241549981
Total Pages : 0 pages
Book Rating : 4.5/5 (499 download)

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Book Synopsis Guidelines on Hepatitis B and C Testing by : World Health Organization

Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Clinical Rounds in Hepatology

Author : Virendra Singh
Publisher : Springer Nature
ISBN 13 : 9811684480
Total Pages : 195 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Clinical Rounds in Hepatology by : Virendra Singh

Download or read book Clinical Rounds in Hepatology written by Virendra Singh and published by Springer Nature. This book was released on 2022-01-29 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive collection of classic cases and problem scenarios encountered as bedside case discussions during ward rounds. It facilitates the practical management of hepatic disorders. The unique aspect of hepatology involves the blend of the basic tenet of clinical medicine applied to liver disease and a multitude of interventional modalities in the management of liver, biliary, and pancreatic diseases. This book takes the reader through the process of ruling in and ruling out possibilities based on clinical data (history and examination) and then traces the logical trajectory of each case from recommended investigations to the analysis of test results and finally to making a syndromic diagnosis. By adopting an evidence-based approach, the book emphasizes analytical and need-based studies to exclude any mimics. This book helps practice hepatologists and gastroenterologists for a systematic approach towards the most common cases.

Cost Effectiveness in Health and Medicine

Author : Peter J. Neumann
Publisher : Oxford University Press
ISBN 13 : 0190492937
Total Pages : 537 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Cost Effectiveness in Health and Medicine by : Peter J. Neumann

Download or read book Cost Effectiveness in Health and Medicine written by Peter J. Neumann and published by Oxford University Press. This book was released on 2017 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: CEAs (cost-effectiveness analyses) are used by decision makers in the health sector to make enlightened evaluations and this book provides an in depth look at how to evaluate the evaluator. The book is aimed specifically at Public health specialists.

New Drug Development for Known and Emerging Viruses

Author : Helga Rübsamen-Schaeff
Publisher : John Wiley & Sons
ISBN 13 : 3527810706
Total Pages : 530 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis New Drug Development for Known and Emerging Viruses by : Helga Rübsamen-Schaeff

Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2021-11-30 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.

WHO guidelines on physical activity and sedentary behaviour

Author :
Publisher : World Health Organization
ISBN 13 : 9240014888
Total Pages : 24 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO guidelines on physical activity and sedentary behaviour by :

Download or read book WHO guidelines on physical activity and sedentary behaviour written by and published by World Health Organization. This book was released on 2020-11-20 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Therapy for Hepatitis C

Author : Geoffrey W. McCaughan
Publisher : John Wiley & Sons
ISBN 13 : 1444346326
Total Pages : 426 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Advanced Therapy for Hepatitis C by : Geoffrey W. McCaughan

Download or read book Advanced Therapy for Hepatitis C written by Geoffrey W. McCaughan and published by John Wiley & Sons. This book was released on 2011-10-05 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatologists, both researchers and front-line clinicians, now have a comprehensive guide to the treatment of patients with the HCV virus. This book focuses mainly on the efficacy and clinical use of antiviral therapies, including the use of antivirals post liver transplantation and in the presence of the HIV virus. It also explores the foundations for understanding antiviral therapies in HCV, such as the complex pharmacology and mechanisms of antiviral drugs. A 'late-breaking information' chapter contains the most recent trial results on the latest antiviral drugs.

The Hepatitis C Help Book

Author : Misha Ruth Cohen
Publisher : Dearborn Trade Publishing
ISBN 13 : 9780312263362
Total Pages : 308 pages
Book Rating : 4.2/5 (633 download)

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Book Synopsis The Hepatitis C Help Book by : Misha Ruth Cohen

Download or read book The Hepatitis C Help Book written by Misha Ruth Cohen and published by Dearborn Trade Publishing. This book was released on 2001-05-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis C has been called "the emergent and preeminent public-health problem of the twenty-first century-surpassing HIV." It has also been dubbed "The Shadow Epidemic," because it is one of the most clandestine of viruses and infects healthy people who have no idea they are being attacked by something they can't even detect. Now, two experts on hepatitis C have teamed up to write a complete guide to orthodox and alternative treatment options. The book includes programs for self-care, nutritional and fitness plans, and a comprehensive Western and Chinese medical treatment program.

Immunotherapy of Hepatocellular Carcinoma

Author : Tim F. Greten
Publisher : Springer
ISBN 13 : 9783319879116
Total Pages : 0 pages
Book Rating : 4.8/5 (791 download)

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Book Synopsis Immunotherapy of Hepatocellular Carcinoma by : Tim F. Greten

Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Advanced Therapy in Gastroenterology and Liver Disease

Author : Theodore M. Bayless
Publisher : PMPH-USA
ISBN 13 : 9781550092486
Total Pages : 892 pages
Book Rating : 4.0/5 (924 download)

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Book Synopsis Advanced Therapy in Gastroenterology and Liver Disease by : Theodore M. Bayless

Download or read book Advanced Therapy in Gastroenterology and Liver Disease written by Theodore M. Bayless and published by PMPH-USA. This book was released on 2005 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main emphasis of this new fifth edition ofAdvanced Therapy of Gastroenterology and Liver Diseaseis on patient management. Chapters are dedicated to general topics in gastroenterology and hepatology practice and the use of diagnostic tests in clinical decision-making. Principles in endoscopy including sedation and infection control are also examined. Each chapter consists of recommendations from an expert in the field concerning a very focused problem. The authors discuss recommendations for instituting, modifying and monitoring therapy, including combinations of drugs and / or therapeutic and diagnostic procedures.

Hepatitis C: Care and Treatment

Author : Angelos Hatzakis
Publisher : Springer Nature
ISBN 13 : 3030677621
Total Pages : 219 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Hepatitis C: Care and Treatment by : Angelos Hatzakis

Download or read book Hepatitis C: Care and Treatment written by Angelos Hatzakis and published by Springer Nature. This book was released on 2021-05-10 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the reader with a detailed overview of the current state-of-the art approach of Hepatitis C management. It reviews the course of action in handling of chronic Hepatitis C patients with various HCV genotypes and treats special cases such as acute hepatitis, transplant and renal patients as well as people who inject drugs. The two volume work on Hepatitis C introduces to the topic by reviewing virology, diagnosis, epidemiology, prevention, management and elimination of HCV. The book provides a valuable source at full length for researchers and clinicians working on Hepatitis C.

The Hepatitis C Help Book

Author : Misha Ruth Cohen
Publisher : Macmillan
ISBN 13 : 0312372728
Total Pages : 338 pages
Book Rating : 4.3/5 (123 download)

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Book Synopsis The Hepatitis C Help Book by : Misha Ruth Cohen

Download or read book The Hepatitis C Help Book written by Misha Ruth Cohen and published by Macmillan. This book was released on 2007-05-15 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the orthodox and alternative treatment options available to patients with Hepatitis C; and provides fitness and nutritional plans, self-help information, and self-care programs.

Advances in Treatment of Hepatitis C and B

Author : Naglaa Allam
Publisher : BoD – Books on Demand
ISBN 13 : 9535129937
Total Pages : 408 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Advances in Treatment of Hepatitis C and B by : Naglaa Allam

Download or read book Advances in Treatment of Hepatitis C and B written by Naglaa Allam and published by BoD – Books on Demand. This book was released on 2017-03-08 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in many areas of medicine, treatment of viral hepatitis has seen an acceleration of change driven by new therapies and evolving technology. Thanks to the direct-acting antiviral agents (DAAs), the era of HCV eradication and cure has begun. As regards to hepatitis B therapy, potent antiviral drugs for suppression of viral replication are available, new research activities to enhance eradication are visible, and these may influence clinical practice in the coming years. This book covers the latest advances in hepatitis C and hepatitis B therapeutics as well as the emerging and investigational treatment strategies. "Advances in Treatment of Hepatitis C and Hepatitis B" book is an up-to-date source of information for physicians, residents, and advanced medical students seeking a broader understanding of treatment of viral hepatitis. The authors of the chapters come from many eminent centers around the world and are experts in their respective fields.

Evidence-Based Advance and Management of Drug Treatment of Infectious Diseases

Author : Yonggang Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2889717992
Total Pages : 166 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Evidence-Based Advance and Management of Drug Treatment of Infectious Diseases by : Yonggang Zhang

Download or read book Evidence-Based Advance and Management of Drug Treatment of Infectious Diseases written by Yonggang Zhang and published by Frontiers Media SA. This book was released on 2021-12-06 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are caused by microorganisms that release toxins or invade body tissues. The most common pathogenic organisms are bacteria, viruses, fungi, protozoa, and helminths. Systemic infections usually cause fevers, chills, sweats, malaise, and occasionally headache, muscle and joint pain, or changes in mental status, and even septic shock-MODS. Infectious diseases have always threatened populations and caused great loss of life in history, but since the last century, with the discovery of antibiotics, historical trends have been reversed. It is reported that between 1990 and 2017, age-standardized disability-adjusted life year (DALY) rates decreased by 41.3% (38.8-43.5) for infectious diseases. However, in 2017, lower respiratory infections are still ranked as the third cause of DALYs. Drug therapy is the one of most critical management strategies for infectious diseases. Efficacy and safety of drug therapy should always be considered, especially in elders, neonates and immunosuppressed patients. Off-label drug therapy has been performed for complex infectious diseases, especially for new emerging infectious diseases. However, off-label drug therapy can be extremely complex: some are prone to rational use, while others are more susceptible to the issues of irrational use. With the increasing rate of publication of data in this area, new evidence for the efficacy and safety of different treatment approaches is constantly developing. Thus, rigorous analysis of such data is imperative, which will guide future clinical practice and guidelines.