Advanced Glycation End Products

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Advanced Glycation End-products

Author : Patrik Bast
Publisher : Nova Science Publishers
ISBN 13 : 9781536175479
Total Pages : 144 pages
Book Rating : 4.1/5 (754 download)

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Book Synopsis Advanced Glycation End-products by : Patrik Bast

Download or read book Advanced Glycation End-products written by Patrik Bast and published by Nova Science Publishers. This book was released on 2020 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Advanced Glycation End-Products: Sources and Effects attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interventions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology"--

Molecular Basis of Nutrition and Aging

Author : Marco Malavolta
Publisher : Academic Press
ISBN 13 : 0128018275
Total Pages : 786 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular Basis of Nutrition and Aging by : Marco Malavolta

Download or read book Molecular Basis of Nutrition and Aging written by Marco Malavolta and published by Academic Press. This book was released on 2016-04-15 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. - Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging - Explores how nutritional factors are involved in the pathogenesis of aging across body systems - Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition

Mechanisms Linking Aging, Diseases and Biological Age Estimation

Author : Sara C. Zapico
Publisher : CRC Press
ISBN 13 : 1315354209
Total Pages : 203 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Mechanisms Linking Aging, Diseases and Biological Age Estimation by : Sara C. Zapico

Download or read book Mechanisms Linking Aging, Diseases and Biological Age Estimation written by Sara C. Zapico and published by CRC Press. This book was released on 2017-03-27 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.

Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus

Author :
Publisher : Academic Press
ISBN 13 : 0128002948
Total Pages : 513 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus by :

Download or read book Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus written by and published by Academic Press. This book was released on 2013-12-24 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research. - Written by experts in the field - Informs on important topics related to the regulation of glucose homeostasis and the pathogenesis of diabetes mellitus, a field of intense research interest

Obesity and Diabetes

Author : Joel Faintuch
Publisher : Springer Nature
ISBN 13 : 3030533700
Total Pages : 994 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Obesity and Diabetes by : Joel Faintuch

Download or read book Obesity and Diabetes written by Joel Faintuch and published by Springer Nature. This book was released on 2020-12-14 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Nutrition in Kidney Disease

Author : Laura D. Byham-Gray
Publisher : Springer Science & Business Media
ISBN 13 : 1627036857
Total Pages : 495 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Nutrition in Kidney Disease by : Laura D. Byham-Gray

Download or read book Nutrition in Kidney Disease written by Laura D. Byham-Gray and published by Springer Science & Business Media. This book was released on 2014-01-23 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and management of kidney failure especially during medical crises, such as acute kidney injury and its consequent nutritional therapies (e.g., enteral and parenteral nutrition). Demographic patterns, trends and outcomes in the current health care systems are explored in the United States and abroad. Disease prevention and management are presented over the entire lifespan, beginning with pregnancy, followed by infancy, childhood, adolescence, and adulthood, concluding with the elder years. Foundations for clinical practice are established by devoting a complete section towards conducting a comprehensive nutritional assessment, comprising of anthropometric, biochemical, clinical, physical parameters and psychosocial concerns unique to the kidney disease population. Nutritional therapy is also discussed across the spectrum of kidney disease, and pertinent aspects critical to successful management of disorders and conditions, such as bone disease, obesity, and nephrotic syndrome are explored. Nutrition in Kidney Disease, Second edition highlights cutting edge research in regards to exercise and functional outcomes, malnutrition and the inflammatory response, experimental therapies, and the use of complementary and alternative medicine, with a special emphasis on relevant preventative strategies.

Dietary Interventions in Liver Disease

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 012814467X
Total Pages : 430 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Dietary Interventions in Liver Disease by : Ronald Ross Watson

Download or read book Dietary Interventions in Liver Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-01-10 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development. - Provides information on agents that affect metabolism and other health-related conditions in the liver - Explores the impact of composition, including differences based on country of origin and processing techniques - Addresses the most positive results from dietary interventions using bioactive foods to impact liver disease, including reduction of inflammation and improved function

New Look to Phytomedicine

Author : Mohd Sajjad Ahmad Khan
Publisher : Academic Press
ISBN 13 : 0128146206
Total Pages : 711 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis New Look to Phytomedicine by : Mohd Sajjad Ahmad Khan

Download or read book New Look to Phytomedicine written by Mohd Sajjad Ahmad Khan and published by Academic Press. This book was released on 2018-10-23 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research. - Compiles up-to-date information on the chemotherapeutics used in the treatment of infective and metabolic disorders - Presents advancements in the discovery of new drugs from plants using molecular and nanotechnology tools - Examines detailed information on the use of herbals agents in cancer, HIV and other ailments, including diabetes, malaria and neurological disorders

The A. G. E. Food Guide

Author : Helen Vlassara
Publisher :
ISBN 13 : 9780757004292
Total Pages : 0 pages
Book Rating : 4.0/5 (42 download)

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Book Synopsis The A. G. E. Food Guide by : Helen Vlassara

Download or read book The A. G. E. Food Guide written by Helen Vlassara and published by . This book was released on 2017-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "All foods contain naturally ocurring toxic substances called AGEs - advanced glycation end products. Studies have shown that a buildup of AGEs increases oxidation and free radicals, hardens tissue, and creates chronic inflammation, leading to a host of illnesses. While many foods contain high AGE levels, many others contain very little. By knowing the best foods to choose and their optimal preparation methods, you can lower your consumption of these harmful substances. The AGE Food Guide is designed to help. This comprehensive guide lists hundreds of common foods and their AGE levels. In an easy-to-follow format, the foods are listed both alphabetically and within categories for quick and easy access." -- p. [4] of cover.

Textbook of Aging Skin

Author : Miranda A. Farage
Publisher : Springer Science & Business Media
ISBN 13 : 3540896554
Total Pages : 1255 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Textbook of Aging Skin by : Miranda A. Farage

Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

Cellular and Biochemical Mechanisms of Obesity

Author : Paramjit S. Tappia
Publisher : Springer Nature
ISBN 13 : 3030847632
Total Pages : 420 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Cellular and Biochemical Mechanisms of Obesity by : Paramjit S. Tappia

Download or read book Cellular and Biochemical Mechanisms of Obesity written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2021-12-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.

Choose Your Foods

Author : The Academy of Nutrition and Dietetics
Publisher :
ISBN 13 : 9780880910408
Total Pages : 0 pages
Book Rating : 4.9/5 (14 download)

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Book Synopsis Choose Your Foods by : The Academy of Nutrition and Dietetics

Download or read book Choose Your Foods written by The Academy of Nutrition and Dietetics and published by . This book was released on 2019-10-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Levin and O'Neal's the Diabetic Foot

Author : Marvin E. Levin
Publisher : Elsevier Health Sciences
ISBN 13 : 0323041450
Total Pages : 648 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Levin and O'Neal's the Diabetic Foot by : Marvin E. Levin

Download or read book Levin and O'Neal's the Diabetic Foot written by Marvin E. Levin and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated, now in full color, this latest edition of Levin and O'Neal's The Diabetic Foot provides diagnostic and management information for the challenging problems faced by patients with diabetic foot problems. The book has a team care focus and offers tips and pearls in every chapter.

Radical Longevity

Author : Ann Louise Gittleman
Publisher : Hachette Go
ISBN 13 : 0306874849
Total Pages : 320 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis Radical Longevity by : Ann Louise Gittleman

Download or read book Radical Longevity written by Ann Louise Gittleman and published by Hachette Go. This book was released on 2021-05-11 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times bestselling author and cutting-edge health expert shares her nutrition-based plan for healthy, vibrant longevity. Welcome to a Radical new view of aging—one that defies conventional wisdom and redefines the aging process with resilience, vitality and grace. You’ll discover the most advanced program that staves off the effects of aging, which includes how to release a lifetime of accumulated toxins and deficiencies—and how to correct and reverse their effects with targeted foods, critical lifestyle tweaks, peptides and signaling molecules for cellular regeneration. With her trademark no-nonsense style, Ann Louise Gittleman champions a paradigm shift in which your biology is not your biography. By utilizing epigenetics to slow and reverse many of the most worrisome aging conditions, you can preserve your “youth span” and enhance your immunity, heart, brain, muscles, joints, skin, and hair. You can even revitalize your sex drive! Based on decades of experience and research in breakthrough age-defying and restorative medicine, Radical Longevity will forever change what you think you know about aging. Inside you’ll discover: The most essential vitamins, minerals and hormones to reclaim youthful immunity The transformative Radical Longevity Power Plan and 5 Day Radical Reset to soothe the gut and revitalize the liver How to manipulate your metabolism The Cinderella mineral to help prevent memory loss and reverse Alzheimer’s How to make your body produce up to fifty percent more “Youth Defying Stem Cells” The #1 brain-aging hazard hiding in your home, and how to activate your best self-defense The unexpected “forbidden” food that makes your skin, joints, eyes, arteries, and brain feel years younger and much more… Radical Longevity casts a big and bold new vision of aging that will give you freedom from accepting the limitations that growing older once meant. Look more youthful, feel more agile, and think more clearly as you enter the Radical new era of healthy aging!

Co- and Post-Translational Modifications of Therapeutic Antibodies and Proteins

Author : T. Shantha Raju
Publisher : John Wiley & Sons
ISBN 13 : 111905334X
Total Pages : 316 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Co- and Post-Translational Modifications of Therapeutic Antibodies and Proteins by : T. Shantha Raju

Download or read book Co- and Post-Translational Modifications of Therapeutic Antibodies and Proteins written by T. Shantha Raju and published by John Wiley & Sons. This book was released on 2019-03-15 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Crucial Attributes of Therapeutic Proteins in Biological Pharmaceuticals With this book, Dr. Raju offers a valuable resource for professionals involved in research and development of biopharmaceutical and biosimilar drugs. This is a highly relevant work, as medical practitioners have increasingly turned to biopharmaceutical medicines in their search for safe and reliable treatments for complex diseases, while pharmaceutical researchers seek to expand the availability of biopharmaceuticals and create more affordable biosimilar alternatives. Readers receive a thorough overview of the major co-translational modifications (CTMs) and post-translational modifications (PTMs) of therapeutic proteins relevant to the development of biotherapeutics. The majority of chapters detail individual CTMs and PTMs that may affect the physicochemical, biochemical, biological, pharmacokinetic, immunological, toxicological etc. properties of proteins. In addition, readers are guided on the methodology necessary to analyze and characterize these modifications. Thus, readers gain not only an understanding of CTMs/PTMs, but also the ability to design and assess their own structure-function studies for experimental molecules. Specific features and topics include: Discussion of the research behind and expansion of biopharmaceuticals Twenty chapters detailing relevant CTMs and PTMs of proteins, such as glycosylation, oxidation, phosphorylation, methylation, proteolysis, etc. Each chapter offers an introduction and guide to the mechanisms and biological significance of an individual CTM or PTM, including practical guidance for experiment design and analysis An appendix of biologic pharmaceuticals currently on the market, along with an assessment of their PTMs and overall safety and efficacy This volume will prove a key reference on the shelves of industry and academic researchers involved in the study and development of biochemistry, molecular biology, biopharmaceuticals and proteins in medicine, particularly as biopharmaceuticals and biosimilars become ever more prominent tools in the field of healthcare.

Collagen

Author : Peter Fratzl
Publisher : Springer Science & Business Media
ISBN 13 : 0387739068
Total Pages : 516 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Collagen by : Peter Fratzl

Download or read book Collagen written by Peter Fratzl and published by Springer Science & Business Media. This book was released on 2008-05-10 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.

Endothelial Dysfunction

Author : Helena Lenasi
Publisher : BoD – Books on Demand
ISBN 13 : 1789842530
Total Pages : 432 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Endothelial Dysfunction by : Helena Lenasi

Download or read book Endothelial Dysfunction written by Helena Lenasi and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.