Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys

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Publisher : Frontiers Media SA
ISBN 13 : 2889719987
Total Pages : 99 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys by : Danielle Elise Soranno

Download or read book Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys written by Danielle Elise Soranno and published by Frontiers Media SA. This book was released on 2022-01-07 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Controversies in Acute Kidney Injury

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805598106
Total Pages : 267 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Controversies in Acute Kidney Injury by : John A. Kellum

Download or read book Controversies in Acute Kidney Injury written by John A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy. The publication at hand contains sections on prerenal azotemia syndromes, dying of' or with' AKI, pathophysiology of sepsis- induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

Continuous Renal Replacement Therapy

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Author :
Publisher : Oxford University Press
ISBN 13 : 019022553X
Total Pages : 329 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Continuous Renal Replacement Therapy by : John A. Kellum

Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Acute Kidney Injury - Basic Research and Clinical Practice

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318063118
Total Pages : 175 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Acute Kidney Injury - Basic Research and Clinical Practice by : X. Ding

Download or read book Acute Kidney Injury - Basic Research and Clinical Practice written by X. Ding and published by Karger Medical and Scientific Publishers. This book was released on 2018-01-23 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Kidney Injury (AKI) is a complex syndrome that is prevalent among hospitalized patients. In recent years, occurrence of AKI events has risen due to a growing susceptibility of fragile and elderly subjects and an increase in the use of complex procedures such as cardiovascular surgery and imaging techniques. Exposure to potentially nephrotoxic drugs, such as new chemotherapeutic agents, is also proving to be a cause of AKI. This book summarizes recent advances in various settings. A reappraisal of current definitions and staging classifications for AKI in the literature is followed by a description of new criteria for identifying patients at risk and characterizing early kidney damage by using biomarkers. Other important topics include the sequelae of AKI and AKI in special populations such as children, the elderly, and those with cancer. The effects of AKI and its consequences on healthcare expenditures are also addressed from several perspectives. AKI management requires the cooperation of different specialists to optimize outcomes. This book is thus a perfect tool not only for nephrologists, but for every specialist involved in the complicated endeavor of improving patient care.

Acute Kidney Injury

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805582714
Total Pages : 477 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Acute Kidney Injury by : Claudio Ronco

Download or read book Acute Kidney Injury written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury is defined as an abrupt change in serum creatinine and/or urine output, and a majority of patients admitted to the ICU have some evidence of the disorder. Unfortunately, treatment for this complex syndrome is as yet lacking and understanding is limited. An interdisciplinary panel of experts has contributed to this volume, illuminating some of the fundamental and complex aspects of the disorder ranging from pathophysiology to treatment, from emerging biomarkers to genetic polymorphisms. Other contributions focus on immunological issues or the many complications of acute kidney injury and co-morbid conditions encountered, covering the fundamentals as well as the latest developments. Moreover, important technical aspects of extracorporeal therapies including vascular access, anticoagulation or fluid composition are introduced, and different approaches to renal support from intermittent dialysis to continuous therapies and hybrid techniques are discussed. A description of advanced extracorporeal techniques of organ support and their role in the management of sepsis and acute kidney injury in the context of an overall strategy of multi-organ failure management concludes the discussions. This volume not only provides a practical and up-to-date summary of current knowledge and technology, but also imparts a fundamental understanding of the pathogenesis and likely future developments in this field. It also serves to challenge and re-examine the fundamental underlying assumptions we hold regarding critical illness in general and acute kidney injury in particular.

Acute Kidney Injury

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Publisher :
ISBN 13 :
Total Pages : 283 pages
Book Rating : 4.:/5 (91 download)

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Book Synopsis Acute Kidney Injury by :

Download or read book Acute Kidney Injury written by and published by . This book was released on 2013 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI), previously called acute renal failure, has chiefly been described as a syndrome since World War 2. Traditionally 'acute renal failure' was regarded as a less common organ failure, with patients typically requiring dialysis and managed by nephrologists. This view has now been overturned. AKI encompasses a wide spectrum of injury to the kidneys, not just kidney failure. It is a common problem amongst hospitalised patients, in particular the elderly population whose numbers are increasing as people live longer. Such patients are usually under the care of doctors practicing in specialties other than nephrology. For normal function the kidneys require a competent circulation. Conversely, it is known that renal function is vulnerable to even relative or quite modest hypotension or hypovolaemia. Hence AKI is a feature of many severe illnesses. Although these illnesses may affect many organs, the simple process of monitoring urine output and/or creatinine permits detection of AKI. There have long been concerns that clinicians may inadvertently contribute to the development of AKI, by their use of drugs that are harmful to the kidneys. However, in spite of its wider adoption in the UK from the 1970's, audit was not fully applied to AKI until the turn of the millennium. A seminal moment was the confidential enquiry into the deaths of a large group of adult patients with AKI, published by the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) in 2009. This described systemic deficiencies in the care of patients who died of AKI including failures in AKI prevention, recognition, therapy and timely access to specialist services. Only 50% of these sick patients received 'good' care. It was clear that many adult specialties needed to greatly improve their recognition and management of AKI and redesign their services. There are also known and unacceptable variations in the recognition, assessment, initial treatment and usage of renal replacement therapy in AKI. Some 20-30% of cases of AKI are regarded partially or fully preventable. Even if only 20% of cases can be prevented or ameliorated, successful preventive measures would produce a large reduction in deaths, complications and costs due to AKI. The NCEPOD report informed a referral from the Department of Health for NICE to develop its first guideline on AKI. The guideline development process is defined by its scope, published after stakeholder consultation. Therefore, the guideline does not cover all aspects of AKI, only addressing areas within the scope. Importantly these guidelines include paediatric acute kidney injury. The scope of the guideline focuses on identifying clinical and cost effective practice that might improve care and outcomes in intervention in the earlier parts of the disease process, including risk assessment and prevention, early recognition and treatment. It does not include evidence regarding aspects of dialysis beyond the decision on its initiation. NICE guidance does not aim to provide a 'textbook' of care for the area under consideration. Thus it is beyond the scope of the guideline to give detailed discussion of the more basic management of AKI causes such as hypovolaemia, sepsis, and nephrotoxins. Instead it aims to distil relevant evidence and use this to provide a set of recommendations. It is primarily aimed at generalist clinicians, who will care for the large majority of patients with AKI in a non-specialist hospital or primary care setting.

Acute Kidney Injury and Regenerative Medicine

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Author :
Publisher : Springer Nature
ISBN 13 : 981151108X
Total Pages : 390 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Acute Kidney Injury and Regenerative Medicine by : Yoshio Terada

Download or read book Acute Kidney Injury and Regenerative Medicine written by Yoshio Terada and published by Springer Nature. This book was released on 2020-05-14 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm

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Author :
Publisher : MDPI
ISBN 13 : 3039360868
Total Pages : 574 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm by : Wisit Cheungpasitporn

Download or read book Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm written by Wisit Cheungpasitporn and published by MDPI. This book was released on 2020-12-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.

Core Concepts in Acute Kidney Injury

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Author :
Publisher : Springer
ISBN 13 : 1493986287
Total Pages : 368 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Core Concepts in Acute Kidney Injury by : Sushrut S. Waikar

Download or read book Core Concepts in Acute Kidney Injury written by Sushrut S. Waikar and published by Springer. This book was released on 2018-09-14 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.

Perioperative Kidney Injury

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Publisher : Springer
ISBN 13 : 1493912739
Total Pages : 257 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Perioperative Kidney Injury by : Charuhas V. Thakar

Download or read book Perioperative Kidney Injury written by Charuhas V. Thakar and published by Springer. This book was released on 2014-10-21 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends the evidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.

Management of Acute Kidney Problems

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Publisher : Springer Science & Business Media
ISBN 13 : 3540694412
Total Pages : 668 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Management of Acute Kidney Problems by : Achim Jörres

Download or read book Management of Acute Kidney Problems written by Achim Jörres and published by Springer Science & Business Media. This book was released on 2010-03-11 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney failure is an important clinical area in the intensive care unit setting. An estimated 5–20% of critically ill patients experience an episode of acute kidney failure during the course of their illness, and about 5% of patients admitted to an ICU will eventually require renal replacement therapy. In these patients, in-hospital mortality is extremely high, exceeding 50%. Thus, the early detection and causal treatment of acute kidney problems is vitally important for a successful outcome. Written by internationally renowned experts, this clinical reference offers helpful advice with the most recent information on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney failure as a fundamental prerequisite for prevention of this disorder. Moreover, it also covers differential diagnostic approaches for patients with acute renal failure and provides a detailed outline of important measures for their clinical management. Finally, separate chapters are dedicated to various key aspects related to the adequate delivery of acute renal replacement therapy. It is intended as a helpful guide for all clinicians involved in the care of patients at risk of developing acute kidney problems.

Acute Kidney Injury - From Diagnosis to Care

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318058262
Total Pages : 158 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Acute Kidney Injury - From Diagnosis to Care by : X. Ding

Download or read book Acute Kidney Injury - From Diagnosis to Care written by X. Ding and published by Karger Medical and Scientific Publishers. This book was released on 2016-02-08 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a serious disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions and exposures. It is very common in (elderly) ICU patients and associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities. Renowned experts from around the world have contributed to this new publication, creating a succinct yet complete review of the most controversial aspects of AKI. The topics range from epidemiology and basic science to pathophysiology and clinical issues. It is intended as a concise reference work for physicians and nurses who deal with AKI in clinical nephrology and intensive care wards on a daily basis.

Cardiorenal Syndromes in Critical Care

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805594739
Total Pages : 377 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Cardiorenal Syndromes in Critical Care by : C. Ronco

Download or read book Cardiorenal Syndromes in Critical Care written by C. Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2010-05-04 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical care nephrology is an emerging multidisciplinary science in which the competences of different specialists are merged to provide a unified diagnostic and therapeutic approach to the critically ill patient. The volume at hand places great emphasis on cardiorenal syndromes and the multidisciplinary collaboration between cardiology and nephrology. Several contributions describe the cardiorenal syndrome in its different varieties and subtypes and report the results from the most recent Acute Dialysis Quality Initiative Consensus Conference, as well as proposing new diagnostic approaches based on early biomarkers of AKI. Other papers discuss advances in technology for renal replacement therapy and multiple organ support therapy. Moreover, special emphasis is placed on the potential role of extracorporeal therapies in patients affected by H1N1 influenza, and a summary of the most recent trials in the field is included.Containing the proceedings of the 2010 International Vicenza Course on Critical Care Nephrology, this publication is a state-of-the-art appraisal of today’s technology and current issues related to cardiorenal syndromes.

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318024074
Total Pages : 218 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes by : J.A. Kellum

Download or read book ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2013-05-14 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.

Critical Care Nephrology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323511996
Total Pages : 1840 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Critical Care Nephrology E-Book by : Claudio Ronco

Download or read book Critical Care Nephrology E-Book written by Claudio Ronco and published by Elsevier Health Sciences. This book was released on 2017-12-14 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more. Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool. Presents information clearly, in a format designed for easy reference – from basic sciences to clinical syndromes to diagnostic tools. Covers special populations such as children, diabetic patients, and the elderly. An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians – anyone who treats critically ill renal patients. Shares a combined commitment to excellence lead by Drs. Claudio Ronco, Rinaldo Bellomo, John Kellum, and Zaccaria Ricci – unparalleled leaders in this field. Addresses key topics with expanded coverage of acute kidney injury, stress biomarkers, and sepsis, including the latest developments on mechanisms and management. Provides up-to-date information on extracorporeal therapies from new editor Dr. Zaccaria Ricci.

The Crush Syndrome (and Lessons Learned from the Marmara Earthquake)

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Author :
Publisher : IOS Press
ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Crush Syndrome (and Lessons Learned from the Marmara Earthquake) by : Mehmet Şükrü Sever

Download or read book The Crush Syndrome (and Lessons Learned from the Marmara Earthquake) written by Mehmet Şükrü Sever and published by IOS Press. This book was released on 2005 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: ARF induced by traumatic rhabdomyolysis and crush syndrome is a well-known complication occurring in the wake of natural or manmade disasters. As a matter of fact, it is the second most frequent cause of death, following the direct traumatic impact. Early recognition of the crush syndrome and rapid initiation of fluid replacement is essential as this can dramatically reduce the incidence of ARF. After the Marmara earthquake of 1999, the Turkish Society of Nephrology, in collaboration with the Renal Disaster Relief Task Force of the International Society of Nephrology, prepared special questionnaires to obtain patient data and follow-up information to analyze the extent of the nephrological problems. This book is based on the 639 cases consequently documented, constituting an unprecedented collection of first-hand experience on crush syndrome-related ARF following earthquakes. In addition to the data / analysis gained from the Marmara earthquake, each chapter also summarizes classical information on crush syndrome. In every major natural catastrophe, a rapid, appropriate and effective international response is essential to minimize losses and be able to adequately treat victims. This can be achieved only by rational planning and the establishment of an infrastructure composed of trained personnel, equipment, supplies and transportation that can be mobilized at a few hours' notice is essential. This book has been written with the intent to make use of the experiences made after the Marmara earthquake to save more lives in similar future disasters.

Nephrology and Public Health Worldwide

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806937X
Total Pages : 369 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Nephrology and Public Health Worldwide by : G.B. Silva Junior

Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.