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Author : Joseph M. Bosilevac
Publisher :
ISBN 13 :
Total Pages : 318 pages
Book Rating : 4.:/5 (414 download)
Download or read book Activating Transcription Factor 1 and Cyclic AMP Response Element Binding Protein written by Joseph M. Bosilevac and published by . This book was released on 1998 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464946272
Total Pages : 32 pages
Book Rating : 4.4/5 (649 download)
Download or read book Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Basic-Leucine Zipper Transcription Factors in a compact format. The editors have built Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Basic-Leucine Zipper Transcription Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author :
Publisher :
ISBN 13 : 9781071608340
Total Pages : pages
Book Rating : 4.6/5 (83 download)
Download or read book Mitochondrial Gene Expression written by and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464953597
Total Pages : 25 pages
Book Rating : 4.4/5 (649 download)
Download or read book Activating Transcription Factors: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Activating Transcription Factors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Activating Transcription Factors in a compact format. The editors have built Activating Transcription Factors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Activating Transcription Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Activating Transcription Factors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Jun Ma
Publisher : Springer
ISBN 13 : 9781441922038
Total Pages : 0 pages
Book Rating : 4.9/5 (22 download)
Download or read book Gene Expression and Regulation written by Jun Ma and published by Springer. This book was released on 2010-12-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive look at the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. The focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Author : Heinz Rupp
Publisher : Springer Science & Business Media
ISBN 13 : 9780792379812
Total Pages : 252 pages
Book Rating : 4.3/5 (798 download)
Download or read book Control of Gene Expression by Catecholamines and the Renin-Angiotensin System written by Heinz Rupp and published by Springer Science & Business Media. This book was released on 2000-11-30 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression. Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of many cells, the intriguing possibility arises that various disease are initiated or aggravated by such an imbalance. Catecholamine and angiotensin II influences can be in excess arising from, for example, hypercaloric food intake or psychosocial stress. During early progression of heart failure, sympathetic activity and angiotensin II influences also become increased. Due to beta-adrenergic receptor downregulation, depressed catecholamine influences are expected in the final stage of heart failure. An imbalanced influence of catecholamines and angiotensin II on gene expression leads to disordered molecular structures of the cell and an impaired cell function. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II. Basic biochemical processes are covered in detail and the potential of these pathways for explaining chronic diseases associated with excess catecholamine and angiotensin II influences should become apparent. It is hoped that this focussed issue triggers novel research into the development of drugs that are targeted at diseases characterized by an imbalanced gene expression involving catecholamines and angiotensin II.
Author :
Publisher : Academic Press
ISBN 13 : 0128191295
Total Pages : 310 pages
Book Rating : 4.1/5 (281 download)
Download or read book Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C written by and published by Academic Press. This book was released on 2020-02-10 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C, Volume 633, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial. This release includes sections on Next generation probes for molecular imaging in cells, Competitive binding assay for biotin and biotin derivatives, based on avidin and biotin-4-fluorescein, Converting avidin to bind ligands other than biotin, especially steroids, Chemoenzymatic Labeling Strategy, Engineered Siderophores, Small molecules to inhibit bacterial population behavior, NMR tube bioreactor, Small molecule controlled RAS activation system, Small molecule regulated Cas9, the Design and application of synthetic receptors, and much more. Contains the authority of authors who are leaders in their field Provides a comprehensive source on new methods and research in enzymology
Author : Thomas Frodl
Publisher : Academic Press
ISBN 13 : 0128026286
Total Pages : 422 pages
Book Rating : 4.1/5 (28 download)
Download or read book Systems Neuroscience in Depression written by Thomas Frodl and published by Academic Press. This book was released on 2016-03-16 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. Knowledge covering the whole life span from early to later life Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience Understanding the neurobiology of major depressive disorder Integrating stress and environmental factors with molecular underpinnings More than 25 illustrations and tables
Author : Gerald Thiel
Publisher : John Wiley & Sons
ISBN 13 : 3527607366
Total Pages : 505 pages
Book Rating : 4.5/5 (276 download)
Download or read book Transcription Factors in the Nervous System written by Gerald Thiel and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases. With a chapter written by Nobel laureate Eric Kandel, this is essential reading for neurobiologists, geneticists, biochemists, cell biologists, neurochemists and molecular biologists.
Author : Michael G. Kaplitt
Publisher : Elsevier
ISBN 13 : 0080454372
Total Pages : 372 pages
Book Rating : 4.0/5 (84 download)
Download or read book Gene Therapy of the Central Nervous System: From Bench to Bedside written by Michael G. Kaplitt and published by Elsevier. This book was released on 2005-11-11 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped create this field and are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects of interest to anyone exploring or using gene therapy for neurobiological applications in research and clinical praxis. * Presents gene transfer technologies with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells * Discusses preclinical areas that are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis * Includes "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481615556
Total Pages : 58 pages
Book Rating : 4.4/5 (816 download)
Download or read book Basic-Leucine Zipper Transcription Factors—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic-Leucine Zipper Transcription Factors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Basic-Leucine Zipper Transcription Fact in a concise format. The editors have built Basic-Leucine Zipper Transcription Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Basic-Leucine Zipper Transcription Fact in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Basic-Leucine Zipper Transcription Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Letícia Rangel
Publisher :
ISBN 13 : 9789535171409
Total Pages : 630 pages
Book Rating : 4.1/5 (714 download)
Download or read book Cancer Treatment written by Letícia Rangel and published by . This book was released on 2013 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling. Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.
Author :
Publisher :
ISBN 13 :
Total Pages : 18 pages
Book Rating : 4.:/5 (742 download)
Download or read book CRE Activation in Antiestrogen Resistance written by and published by . This book was released on 2005 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: HXBP-1, a basic leucine zipper protein (bZIP), is a transcription factor that belongs to the activating transcription factor/cAMP response element-binding protein (ATF/CRE) family of transcription factors and can bind to and activate the cyclic AMP response elements (OREs). In our previous studies, serial analysis of gene expression has shown that hXBP-1 may contribute to antiestrogen resistance in human breast cancer cells. In antiestrogen resistant cells ORE-regulated transcription (promoter- reporter assay) activity is increased 4-fold. Thus, the purpose of our experiments is to determine whether hXBP-1/CRE contributes to antiestrogen resistance by overexpressing hXBP-1 in cell lines that are sensitive to antiestrogens. T-47D and MCF-7 cells were transfected with hXBP-1 cDNA. Western blotting showed increased expression in transfectants; activity of this protein was confirmed in a promoter - reporter assay measuring luciferase activity as an indicator of ORE activation. Our data show that T-47D and MCF-7 cells over-expressing hXBP-1, when exposed to antiestrogens such as 4-hydroxy- Tamoxifen (TAM) and 101182, 780 (FAS), are able to survive the growth inhibitory effects of these antiestrogens when compared to the empty vector controls of T-47D and MCF-7 cells. Similar observations were observed when both cell types were grown in media devoid of estrogen (E2).
Author : Thomas Steckler
Publisher : Elsevier
ISBN 13 : 9780444511737
Total Pages : 864 pages
Book Rating : 4.5/5 (117 download)
Download or read book Handbook of Stress and the Brain Part 1: The Neurobiology of Stress written by Thomas Steckler and published by Elsevier. This book was released on 2005-03-24 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms
Author :
Publisher : Academic Press
ISBN 13 : 0080884229
Total Pages : 719 pages
Book Rating : 4.0/5 (88 download)
Download or read book G Protein Pathways, Part A: Receptors written by and published by Academic Press. This book was released on 2001-10-09 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.
Author : Ann Arvin
Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)
Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author : Byung Hong Kim
Publisher : Cambridge University Press
ISBN 13 : 1107171733
Total Pages : 509 pages
Book Rating : 4.1/5 (71 download)
Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
