Acetylcholine Receptors In Health And Disease

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Nicotinic Acetylcholine Receptors in Health and Disease

Author : R. Thomas Boyd
Publisher : Academic Press
ISBN 13 : 0128204184
Total Pages : 292 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nicotinic Acetylcholine Receptors in Health and Disease by : R. Thomas Boyd

Download or read book Nicotinic Acetylcholine Receptors in Health and Disease written by R. Thomas Boyd and published by Academic Press. This book was released on 2023-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicotinic Acetylcholine Receptors in Health and Disease provides the latest information Nicotinic acetylcholine receptors (nAChRs), which are involved in numerous diseases, including Alzheimer’s, Parkinson’s, and schizophrenia, and are important potential translational targets for treatment of these diseases, as well as therapy for addiction. This book focuses on the roles and function of nAChRs inside and outside of the nervous system, with an emphasis on translational implications and future prospects for the treatment of numerous disorders. This greater understanding of the basic neurobiology and clinical roles of nAChRs provides important insights for future clinical treatments of many major disorders. Describes the roles, expression and function of nicotinic receptors Includes receptor involvement, both inside and outside the nervous system Details nicotinic receptor involvement in Alzheimer’s, Parkinson’s, Cancer, Schizophrenia, and more Emphasizes future treatment prospects of disorders via modulation of nAChR signaling

Acetylcholine Receptors in Health and Disease

Author : Adelais Eros Gupta
Publisher : Nova Medicine and Health
ISBN 13 : 9781536154474
Total Pages : 117 pages
Book Rating : 4.1/5 (544 download)

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Book Synopsis Acetylcholine Receptors in Health and Disease by : Adelais Eros Gupta

Download or read book Acetylcholine Receptors in Health and Disease written by Adelais Eros Gupta and published by Nova Medicine and Health. This book was released on 2019 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetylcholine Receptors in Health and Disease opens with a review of the results of an investigation on the cholinergic modulation of excitatory synaptic transmission in the frog tectum carried out in the laboratory of neurophysiology at the Lithuanian University of Health Sciences. Experiments were done in vivo on the common grass frog Rana temporaria. Next, the authors review the function of M4 MR and discuss possible detection methods. M4 MR regulated locomotion is studied in conjunction with recent data on consequences to biorhythms. In the closing chapter, the authors review the environmental enrichment paradigm in rodents, as well as their effects on neurobiological, physiological and behavioral variables in preclinical studies.

The Muscle-type Nicotinic Acetylcholine Receptor in Health and Disease

Author : Hakan Cetin
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis The Muscle-type Nicotinic Acetylcholine Receptor in Health and Disease by : Hakan Cetin

Download or read book The Muscle-type Nicotinic Acetylcholine Receptor in Health and Disease written by Hakan Cetin and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuronal Nicotinic Acetylcholine Receptors in the Human Thalamus and Related Brain Areas in Health and Disease

Author : Melissa Ray
Publisher :
ISBN 13 :
Total Pages : 298 pages
Book Rating : 4.:/5 (621 download)

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Book Synopsis Neuronal Nicotinic Acetylcholine Receptors in the Human Thalamus and Related Brain Areas in Health and Disease by : Melissa Ray

Download or read book Neuronal Nicotinic Acetylcholine Receptors in the Human Thalamus and Related Brain Areas in Health and Disease written by Melissa Ray and published by . This book was released on 2005 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Imaging of the Human Brain in Health and Disease

Author : Philip Seeman
Publisher : Elsevier
ISBN 13 : 012418684X
Total Pages : 534 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Imaging of the Human Brain in Health and Disease by : Philip Seeman

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

The Brain Cholinergic System in Health and Disease

Author : Ezio Giacobini
Publisher :
ISBN 13 :
Total Pages : 274 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis The Brain Cholinergic System in Health and Disease by : Ezio Giacobini

Download or read book The Brain Cholinergic System in Health and Disease written by Ezio Giacobini and published by . This book was released on 2006 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Models of Cognitive Impairment

Author : Edward D. Levin
Publisher : CRC Press
ISBN 13 : 1420004336
Total Pages : 395 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Animal Models of Cognitive Impairment by : Edward D. Levin

Download or read book Animal Models of Cognitive Impairment written by Edward D. Levin and published by CRC Press. This book was released on 2006-06-22 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen

Food Components to Enhance Performance

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030905088X
Total Pages : 560 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Food Components to Enhance Performance by : Institute of Medicine

Download or read book Food Components to Enhance Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.

Muscarinic Receptors

Author : Allison D. Fryer
Publisher : Springer Science & Business Media
ISBN 13 : 3642232744
Total Pages : 501 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Muscarinic Receptors by : Allison D. Fryer

Download or read book Muscarinic Receptors written by Allison D. Fryer and published by Springer Science & Business Media. This book was released on 2012-01-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and exploited for both therapeutic and non-therapeutic purposes for hundreds of years before the existence of the receptors themselves was recognized. This volume presents a broad yet detailed review of current knowledge of muscarinic receptors that will be valuable both to long-time muscarinic investigators and to those new to the field. It describes the detailed insights that have been obtained on the structure, function, and cell biology of muscarinic receptors. This volume also describes physiological analyses of muscarinic receptors and their roles in regulating the function of the brain and of a variety of peripheral tissues. This volume shows how the study of muscarinic receptors continues to provide new and surprising insights not just to the cholinergic system but to the broad areas of neurobiology, cell biology, pharmacology, and therapeutics.

Neuroimaging

Author : Peter Bright
Publisher : IntechOpen
ISBN 13 : 9789535102007
Total Pages : 592 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis Neuroimaging by : Peter Bright

Download or read book Neuroimaging written by Peter Bright and published by IntechOpen. This book was released on 2012-03-09 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging tools allow unprecedented opportunities for understanding brain neuroanatomy and function in health and disease. Each available technique carries with it a particular balance of strengths and limitations, such that converging evidence based on multiple methods provides the most powerful approach for advancing our knowledge in the fields of clinical and cognitive neuroscience. The scope of this book is not to provide a comprehensive overview of methods and their clinical applications but to provide a "snapshot" of current approaches using well established and newly emerging techniques.

Tobacco Smoking and Nicotine

Author : William R. Martin
Publisher : Springer Science & Business Media
ISBN 13 : 1461319110
Total Pages : 512 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Tobacco Smoking and Nicotine by : William R. Martin

Download or read book Tobacco Smoking and Nicotine written by William R. Martin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicotine is the major factor in the continuation of the smoking habit among humans. On December 2-4, 1985, under the sponsorship of the Tobacco and Health Research Institute in Lexington, Kentucky, leading scientists from around the world whose research efforts have focused on the role of nicotine in the tobacco habit participated in an International Symposium to provide the most comprehensive and ~xtensive coverage of this topic so far. The material discussed was in the forefront of man's knowledge about nicotine, and both lectures and question and answer sessions were stimulating and enlightening. This publication contains the manuscripts presented at the Symposium, along with an Overview prepared by selected individuals. Lecture and poster session topics are delineated more fully in the Overview. This volume is expected to serve as a definitive reference on nicotine as it relates to the tobacco habit. Symposium sessions were arranged under four headings: (1) behavioral effects of nicotine and nicotine~ependence in humans and animals, (2) neurohumoral regulation of neuroendocrine and cardiovascular function by nicotine, (3) neuropharmacology of nicotine, and (4) neurochemistry. This was the first assembly of this magnitude of scientists who had devoted years of research to nicotine and its effects. Indeed, it was a pleasure to have sponsored this important event. Dr. Lay ten Davis, Director Tobacco and Health Research Institute Cooper and Alumni Drives Lexington, KY 40546-0236 v ACKNOWLEDGMENTS The Editors of this volume express sincere appreciation to all of the contributors. Special acknowledgments are given to Ms.

Nutrition and Traumatic Brain Injury

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309210089
Total Pages : 444 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Nutrition and Traumatic Brain Injury by : Institute of Medicine

Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Methods of Behavior Analysis in Neuroscience

Author : Jerry J. Buccafusco
Publisher : CRC Press
ISBN 13 : 1420041819
Total Pages : 341 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Methods of Behavior Analysis in Neuroscience by : Jerry J. Buccafusco

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Myasthenia Gravis and Related Disorders

Author : Henry J. Kaminski
Publisher : Springer Science & Business Media
ISBN 13 : 1592593410
Total Pages : 397 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Myasthenia Gravis and Related Disorders by : Henry J. Kaminski

Download or read book Myasthenia Gravis and Related Disorders written by Henry J. Kaminski and published by Springer Science & Business Media. This book was released on 2002-10-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

Myasthenia Gravis

Author : Premkumar Christadoss
Publisher : Springer Science & Business Media
ISBN 13 : 940114060X
Total Pages : 220 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Myasthenia Gravis by : Premkumar Christadoss

Download or read book Myasthenia Gravis written by Premkumar Christadoss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized. Antibodies to acetylcholine receptors destroy acetylcholine receptor at the neuromuscular junction, thus leading to defective neuromuscular transmission, muscle fatigue, and weakness. In the last few years, rapid advances have been made in unraveling the cellular and molecular mechanisms involved in the pathogenesis of MG, both in the animal model, experimental autoimmune MG (EAMG), and in human MG. Significant advances are being made in characterizing the cells and molecules involved in the autoimmune response to the acetylcholine receptor (AChR). These advances are leading to the development of specific methods of immunointervention in EAMG. Further understanding of the intricate involvement of the major histocompatibility complex (MHC) and non-MHC genes, T cell receptors (TCR), costimulator molecules, and specific cytokines in the afferent and efferent autoimmune response of AChR should pave the way to future antigen/clone-specific therapy of MG. This book is the outcome of the MG workshop proceedings in Mysore, India, 1998. The majority of the chapters in this book are contributed by world-renowned authors and their students. The book not only contains a timely review of specific topics, but also up-to-date findings. Immunologists and neurologists will find, in this volume, the latest in MG/EAMG cutting-edge research. Clinicians will be interested in the applications of the various immunointervention strategies into clinical trials in MG patients. Finally, students will not only be interested in reading the latest in EAMG/MG research, but will also find information to help them develop a future strategy to unravel the precise mechanism of disease. To summarize, in this book, the readers should find up-to-date information related to immunological mechanisms involved in MG pathogenesis and various modalities for possible approaches to immunointervention to treat MG.

Enteric Glia

Author : Brian D. Gulbransen
Publisher : Biota Publishing
ISBN 13 : 1615046615
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Enteric Glia by : Brian D. Gulbransen

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Anesthesiology

Author : Linda S. Aglio
Publisher : Springer
ISBN 13 : 3319501410
Total Pages : 457 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Anesthesiology by : Linda S. Aglio

Download or read book Anesthesiology written by Linda S. Aglio and published by Springer. This book was released on 2017-07-25 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into twelve sections that cover the entirety of anesthetic practice, this is a case-based, comprehensive review of anesthesiology that covers the basics of anesthetic management and reflects all new guidelines and recently developed standards of care. Each chapter of Anesthesiology: Clinical Case Reviews begins with a specific clinical problem or a clinical case scenario, followed by concise discussions of preoperative assessment, intraoperative management, and postoperative pain management. In addition to residents and fellows, this book is written for practicing anesthesiologists, student nurse anesthetists, and certified registered nurse anesthetists (CRNAs).