Some Antiviral and Antineoplastic Drugs, and Other Pharmaceutical Agents

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Some Antiviral and Antineoplastic Drugs, and Other Pharmaceutical Agents by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Antiviral and Antineoplastic Drugs, and Other Pharmaceutical Agents written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2000 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates the carcinogenic risks to humans posed by the use of four antiretroviral agents four DNA topoisomerase II inhibitors used in the treatment of cancer and an additional three pharmaceutical agents (hydroxyures phenolphthalein and vitamin K substances). The volume marks the first IARC evaluation of nucleoside analogs that act as antiviral agents. The evaluation responds in part to recent findings that zidovudine (AZT) an effective antiretroviral agent now being given to pregnant HIV-infected women to prevent maternal-to-fetal transmission of the virus is a transplacental carcinogen in mice. The opening monograph evaluates the carcinogenicity to humans of the antiretroviral nucleoside analogs zidovudine (AZT) zalcitabine (ddC) and didanosine (ddI) and the antiherpesvirus drug aciclovir. Of these aciclovir and didanosine could not be classified on the basis of available data. For zidovudine transplacental administration to mice resulted in an increased incidence and multiplicity of lung and liver tumours and in an increased incidence of female reproductive tract tumours in one study but not in another involving treatment at a lower dose. Despite observation of toxic effects in some studies of humans human carcinogenicity data were judged to provide inadequate evidence of carcinogenicity in humans. Zidovudine was classified as possibly carcinogenic to humans. Similar weaknesses in human carcinogenicity data for zalcitabine which consistently induces thymic lymphomas in mice resulted in its classification as possibly carcinogenic to humans. The second monograph evaluates four DNA topoisomerase II inhibitors: etoposide teniposide mitoxantrone and amsacrine. Of these etoposide - one of the most widely used and effective cytotoxic drugs in combination therapy - was classified as probably carcinogenic to humans and etoposide in combination with cisplatin and bleomycin was judged to be carcinogenic to humans. Teniposide was classified as probably carcinogenic to humans and mitoxantrone and amsacrine were classified as possibly carcinogenic to humans. Of the three pharmaceutical agents evaluated in the final monograph hydroxyurea which is widely used in cancer treatment and increasingly in combination with didanosine in HIV infection could not be classified. Phenolphthalein a widely used laxative now being withdrawn from the market in many countries because of toxicological concerns was classified as possibly carcinogenic. Vitamin K substances could not be classified on the basis of available evidence.

Comprehensive Cervical Cancer Control

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Publisher : World Health Organization
ISBN 13 : 9241547006
Total Pages : 284 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Comprehensive Cervical Cancer Control by : World Health Organization

Download or read book Comprehensive Cervical Cancer Control written by World Health Organization and published by World Health Organization. This book was released on 2006 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most women who die from cervical cancer, particularly in developing countries, are in the prime of their life. They may be raising children, caring for their family, and contributing to the social and economic life of their town or village. Their death is both a personal tragedy, and a sad and unnecessary loss to their family and their community. Unnecessary, because there is compelling evidence, as this Guide makes clear, that cervical cancer is one of the most preventable and treatable forms of cancer, as long as it is detected early and managed effectively. Unfortunately, the majority of women in developing countries still do not have access to cervical cancer prevention programmes. The consequence is that, often, cervical cancer is not detected until it is too late to be cured. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. It focuses on the knowledge and skills needed by health care providers, at different levels of care.

Critical Care Nursing

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Publisher : Saunders
ISBN 13 :
Total Pages : 1242 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Critical Care Nursing by : Linda Diann Urden

Download or read book Critical Care Nursing written by Linda Diann Urden and published by Saunders. This book was released on 2010 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on critical care nursing, this full-color text provides an examination of the important aspects of critical care nursing. It is organized in ten units around alterations in body systems.

Biotechnology and Sustainable Development

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Publisher : CABI
ISBN 13 : 9780851996752
Total Pages : 340 pages
Book Rating : 4.9/5 (967 download)

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Book Synopsis Biotechnology and Sustainable Development by : Ismail Serageldin

Download or read book Biotechnology and Sustainable Development written by Ismail Serageldin and published by CABI. This book was released on 2003 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the first scientific conference convened at the Library of Alexandria, 'Biotechnology and Sustainable Development: Voices of the South and North', which was held in Alexandria, Egypt, in March 2002, this book contains overviews of agriculture, health, ethics and the environment. It discusses how dramatic improvements in food security, health, and lifestyle could accrue to the poor people of developing countries through the applications of new technologies.

Dictionnaire des termes de médecine

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Publisher :
ISBN 13 :
Total Pages : 262 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Dictionnaire des termes de médecine by : Henry Eugène de Méric

Download or read book Dictionnaire des termes de médecine written by Henry Eugène de Méric and published by . This book was released on 1899 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Psychoanalysis

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Publisher : Polity
ISBN 13 : 0745632696
Total Pages : 425 pages
Book Rating : 4.7/5 (456 download)

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Book Synopsis Psychoanalysis by : Serge Moscovici

Download or read book Psychoanalysis written by Serge Moscovici and published by Polity. This book was released on 2008-02-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book lays the foundation to the author's widely acclaimed theory of social representations, a theory that re-defines the field of social psychology, its problems, concepts and their symbolic and communicative functions, and that formulates a profoundly interactive study of complex social phenomena.

Illness and Self in Society

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Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 (49 download)

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Book Synopsis Illness and Self in Society by : Claudine Herzlich

Download or read book Illness and Self in Society written by Claudine Herzlich and published by . This book was released on 1987 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is the way in which we perceive illness a development of the nineteenth century, when the calamitous epidemics of earlier times gave way to the new scourge of tuberculosis? The authors take an extraordinarily wide-ranging and provocative look at illness as a social phenomenon from the Middle Ages to the present- and uncover the multiple ideas and realities behind what we have come to call "a sick person." Drawing upon the history of medicine and mentalities, on literary representations as well as on hundreds of conversation with people suffering from or living with disease, the authors have explored the very different ways in which every society structures illness and the status of the ill in accord with its own values. And they have explicated the changing ways in which the sick have perceived the presence of illness in their own bodies, have absorbed the medical knowledge of their time, and have sought to give meaning to their sufferings. -- From Book Jacket.

Chemical Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1118681878
Total Pages : 494 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemical Analysis by : Francis Rouessac

Download or read book Chemical Analysis written by Francis Rouessac and published by John Wiley & Sons. This book was released on 2013-05-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail. Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques Maintains a careful balance between depth and breadth of coverage Includes examples, problems and their solutions Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis

Molecular Mechanisms of Hormone Action

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Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Mechanisms of Hormone Action by : Gesellschaft für Biologische Chemie. Colloquium

Download or read book Molecular Mechanisms of Hormone Action written by Gesellschaft für Biologische Chemie. Colloquium and published by . This book was released on 1989 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Pain Relief

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Publisher : World Health Organization
ISBN 13 : 9789241544825
Total Pages : 74 pages
Book Rating : 4.5/5 (448 download)

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Book Synopsis Cancer Pain Relief by : World Health Organization

Download or read book Cancer Pain Relief written by World Health Organization and published by World Health Organization. This book was released on 1996 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a guide, which introduced a simple, yet highly effective method for the relief of cancer pain. Thoroughly revised and updated, the new edition further refines the WHO method, which advocates the use of a small number of relatively inexpensive drugs, including morphine. Revisions draw on experiences with millions of patients around the world as well as new knowledge about the specific pain syndromes unique to cancer. Completely new are chapters describing the international system by which morphine and other opioids are made available for medical purposes. The book has two parts. Part one provides a practical guide to the relief of cancer pain, concentrating on drug treatment as the mainstay of pain management. The most extensive section sets out detailed guidelines for the selection and prescribing of non-opioid analgesics, opioid analgesics, drugs for neuropathic pain, and adjuvant drugs for the treatment of adverse effects, the enhancement of pain relief and the management of concomitant psychological disturbances. Information ranges from explanations of how specific drugs work, through the precautions to take in the presence of certain disorders, to a list of factors that influence the effectiveness of opioids. Concerning the use of opioids, readers are reminded that psychological dependence does not occur in cancer patients and that the only correct dose of morphine is the one that relieves the pain. Part two provides a guide to opioid availability. A discussion of the reasons why opioids continue to be underprescribed or difficult to obtain is followed by an explanation of the Single Convention on Narcotic Drugs.

World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses

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Publisher :
ISBN 13 : 9789241548120
Total Pages : 166 pages
Book Rating : 4.5/5 (481 download)

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Book Synopsis World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses by : World Health Organization

Download or read book World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses written by World Health Organization and published by . This book was released on 2012 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines have been developed to support countries to relieve pain in their paediatric populations. These guidelines address persisting pain in children caused by conditions such as cancer, HIV/AIDS, sickle-cell disease, burns, trauma, and phantom limb pain. Recommendations -- developed following a careful and transparent appraisal of available evidence -- are presented for the pharmacological treatment of mild, moderate and severe pain. The guidelines include chapters on the various systems used to classify pain and on the evaluation of pain, which reviews the available tools for routine pain measurement in children. Provision of sustainable pain relief within health care systems is covered in a separate chapter. Since morphine and other opioid analgesics -- required for the relief of moderate-to-severe pain in children -- are listed under the 1961 UN Single Convention on Narcotic Drugs, the new guidelines include an annex explaining the Convention's requirements for the handling and procurement of opioid analgesics for the relief of pain.

Lying and Illness

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Author :
Publisher : Het Spinhuis
ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Lying and Illness by : Els van Dongen

Download or read book Lying and Illness written by Els van Dongen and published by Het Spinhuis. This book was released on 2005 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lying rearranges human relationships, contests ideologies and cultural assumptions, and manipulates social reality. In this volume, lying will be shown as one fundamental way of dealing with major issues and challenges with which individuals are confronted, such as health, body and identity concerns. In studying lying in the context of health and illness, the contributors explore the ways people gain power, or negotiate power within the limitations of ethical and moral arrangements they cannot effectively challenge. They consider whether lying is a part of the domain of medicine in particular and the specific benefit people draw or seek from lying in the domain of illness and medicine. Els van Dongen is an anthropologist and lecturer in the Department of Anthropology and Sociology at the University of Amsterdam and a staff member of the Amsterdam School for Social Science Research (ASSR). Sylvie Fainzang is an anthropologist and research fellow at the CERMES in Paris and the CNRS in Aix, France.

Human Anatomy

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Publisher :
ISBN 13 : 9788870517897
Total Pages : 0 pages
Book Rating : 4.5/5 (178 download)

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Book Synopsis Human Anatomy by : Giuseppe Anastasi

Download or read book Human Anatomy written by Giuseppe Anastasi and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Capillary Electrophoresis - Mass Spectrometry (CE-MS)

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Publisher : John Wiley & Sons
ISBN 13 : 3527339248
Total Pages : 364 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Capillary Electrophoresis - Mass Spectrometry (CE-MS) by : Gerhardus de Jong

Download or read book Capillary Electrophoresis - Mass Spectrometry (CE-MS) written by Gerhardus de Jong and published by John Wiley & Sons. This book was released on 2016-09-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diese Monographie bietet einen vollständigen Überblick über die Prinzipien und Anwendungen der Kapillarelektrophorese (CE) und der Massenspektrometrie (MS) und legt den Nachdruck insbesondere auf Kopplungsschnittstellen. Ausführlich erläutert werden auch alle relevanten Substanzklassen. Ein einzigartiges Wissenskompendium für alle, die sich CE-MS beschäftigen!

Handbook of Clinical Nanomedicine

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Publisher : Pan Stanford
ISBN 13 : 9789814669221
Total Pages : 0 pages
Book Rating : 4.6/5 (692 download)

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Book Synopsis Handbook of Clinical Nanomedicine by : Raj Bawa

Download or read book Handbook of Clinical Nanomedicine written by Raj Bawa and published by Pan Stanford. This book was released on 2015-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exciting advances in nanomedicine in the past two decades highlight the growing need for an authoritative and comprehensive reference that can be relied upon by scientists, clinicians, academics, industry, students, lawyers, and policy-makers alike. With this in mind, the Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk and its related companion volumes in the series aim to provide a broad survey of interconnected topics pertaining to clinical nanomedicine. This is the second volume in the series. Each volume is intended to be a stand‐alone reference source, presented in a user-friendly format for easy access. This volume examines nanomedical products’ entire "product life cycle" from the creation of nanomedical products to the final market introduction. It not only provides a comprehensive roadmap of basic and clinical research but also tackles critical topics such as regulatory science, intellectual property law, risk analysis, toxicology, nano-characterization, and commercialization activities. All chapters contain keywords, figures in full color, author biographies, and an extensive list of references. The handbook is truly essential reading for the novice and the expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, policy, future studies, ethics, licensing, and toxicology, among others. While bridging the gap between basic biomedical research, engineering, medicine, law, and commercialization, the handbook allows readers to gain a thorough understanding of nano’s potential to address medical problems from both the patient and the health provider’s point of view; current applications and potential in a healthcare setting; regulatory, environment, and health issues; and intellectual property, licensing, and commercialization issues as well as business considerations. The editor and assistant editors have skillfully curated each chapter to reflect the most relevant and current information possible. The range of topics covered as well as the diverse selection of distinguished authors is truly impressive. The multidisciplinary approach of this handbook as well as its focus on not only scientific and technical aspects of nanomedicine but also legal, regulatory, policy, and commercial aspects will attract a global audience. In short, the Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk promises to be a standard reference for any serious practitioner in this expansive field.

Discover Biology

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Publisher : Sunderland, Mass. : Sinauer Associates
ISBN 13 : 9780393940558
Total Pages : 800 pages
Book Rating : 4.9/5 (45 download)

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Book Synopsis Discover Biology by : Michael Lee Cain

Download or read book Discover Biology written by Michael Lee Cain and published by Sunderland, Mass. : Sinauer Associates. This book was released on 2002 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, Discover Biology, Second Edition, presents the essential concepts of modern biology in a text designed specifically for nonmajors. The authors emphasize a level of detail appropriate for nonmajors, freeing instructors to focus on the scientific issues-HIV, global climate change, DNA fingerprinting, genetic engineering, cancer-that students read about in the paper, vote on in elections, and face in their daily lives. With two new chapters, refined pedagogy and art programs, and a powerful ancillary package, Discover Biology, Second Edition, is the best choice for the nonmajors introductory course.

Anticancer Molecules

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Publisher :
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Anticancer Molecules by : Hiroshi Maruta

Download or read book Anticancer Molecules written by Hiroshi Maruta and published by . This book was released on 1999 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses the value of research on tumor suppressor genes and the structure-function relationship of the corresponding proteins. The applicability of these non-peptide molecules to anti-cancer drugs is also taken up; and by focusing on contemporary research issues in the field, the book aims to promote understanding and cooperation between industrial and academic researchers.