A Survey of Models for Tumor-Immune System Dynamics

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Publisher : Springer Science & Business Media
ISBN 13 : 0817681191
Total Pages : 357 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis A Survey of Models for Tumor-Immune System Dynamics by : John A. Adam

Download or read book A Survey of Models for Tumor-Immune System Dynamics written by John A. Adam and published by Springer Science & Business Media. This book was released on 2012-10-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Modeling and Immunology An enormous amount of human effort and economic resources has been directed in this century to the fight against cancer. The purpose, of course, has been to find strategies to overcome this hard, challenging and seemingly endless struggle. We can readily imagine that even greater efforts will be required in the next century. The hope is that ultimately humanity will be successful; success will have been achieved when it is possible to activate and control the immune system in its competition against neoplastic cells. Dealing with the above-mentioned problem requires the fullest pos sible cooperation among scientists working in different fields: biology, im munology, medicine, physics and, we believe, mathematics. Certainly, bi ologists and immunologists will make the greatest contribution to the re search. However, it is now increasingly recognized that mathematics and computer science may well able to make major contributions to such prob lems. We cannot expect mathematicians alone to solve fundamental prob lems in immunology and (in particular) cancer research, but valuable sup port, however modest, can be provided by mathematicians to the research aspirations of biologists and immunologists working in this field.

A Survey of Models for Tumor-Immune System Dynamics

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Publisher :
ISBN 13 : 9780817681203
Total Pages : 364 pages
Book Rating : 4.6/5 (812 download)

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Book Synopsis A Survey of Models for Tumor-Immune System Dynamics by : John A Adam

Download or read book A Survey of Models for Tumor-Immune System Dynamics written by John A Adam and published by . This book was released on 1996-12-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Survey of Models for Tumor-Immune System Dynamics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780817639013
Total Pages : 368 pages
Book Rating : 4.6/5 (39 download)

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Book Synopsis A Survey of Models for Tumor-Immune System Dynamics by : John A. Adam

Download or read book A Survey of Models for Tumor-Immune System Dynamics written by John A. Adam and published by Springer Science & Business Media. This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is a collection of seven interdisciplinary surveys on modeling tumor dynamics and interactions between tumors and immune system. The goal is to provide an accessible, comprehensive report on the field and to help define a framework for future interdisciplinary research activity. Modeling and simulation of general behaviors of immune systems are also discussed. Each survey carefully covers a specialized field and provides a detailed description of the present state-of-the-art in research. The reader will be able to obtain essential information on the methodological approach used and on the models that are categorized and used. The book is an excellent resource and survey for applied mathematicians, mathematical biologists and biologists interested in modeling methods in immunology and related sciences.

Mathematics in Nature

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Publisher : Princeton University Press
ISBN 13 : 1400841011
Total Pages : 408 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Mathematics in Nature by : John Adam

Download or read book Mathematics in Nature written by John Adam and published by Princeton University Press. This book was released on 2011-10-02 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: From rainbows, river meanders, and shadows to spider webs, honeycombs, and the markings on animal coats, the visible world is full of patterns that can be described mathematically. Examining such readily observable phenomena, this book introduces readers to the beauty of nature as revealed by mathematics and the beauty of mathematics as revealed in nature. Generously illustrated, written in an informal style, and replete with examples from everyday life, Mathematics in Nature is an excellent and undaunting introduction to the ideas and methods of mathematical modeling. It illustrates how mathematics can be used to formulate and solve puzzles observed in nature and to interpret the solutions. In the process, it teaches such topics as the art of estimation and the effects of scale, particularly what happens as things get bigger. Readers will develop an understanding of the symbiosis that exists between basic scientific principles and their mathematical expressions as well as a deeper appreciation for such natural phenomena as cloud formations, halos and glories, tree heights and leaf patterns, butterfly and moth wings, and even puddles and mud cracks. Developed out of a university course, this book makes an ideal supplemental text for courses in applied mathematics and mathematical modeling. It will also appeal to mathematics educators and enthusiasts at all levels, and is designed so that it can be dipped into at leisure.

Mathematical Models of Tumor-Immune System Dynamics

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Publisher : Springer
ISBN 13 : 1493917935
Total Pages : 282 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Mathematical Models of Tumor-Immune System Dynamics by : Amina Eladdadi

Download or read book Mathematical Models of Tumor-Immune System Dynamics written by Amina Eladdadi and published by Springer. This book was released on 2014-11-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of papers offers a broad synopsis of state-of-the-art mathematical methods used in modeling the interaction between tumors and the immune system. These papers were presented at the four-day workshop on Mathematical Models of Tumor-Immune System Dynamics held in Sydney, Australia from January 7th to January 10th, 2013. The workshop brought together applied mathematicians, biologists, and clinicians actively working in the field of cancer immunology to share their current research and to increase awareness of the innovative mathematical tools that are applicable to the growing field of cancer immunology. Recent progress in cancer immunology and advances in immunotherapy suggest that the immune system plays a fundamental role in host defense against tumors and could be utilized to prevent or cure cancer. Although theoretical and experimental studies of tumor-immune system dynamics have a long history, there are still many unanswered questions about the mechanisms that govern the interaction between the immune system and a growing tumor. The multidimensional nature of these complex interactions requires a cross-disciplinary approach to capture more realistic dynamics of the essential biology. The papers presented in this volume explore these issues and the results will be of interest to graduate students and researchers in a variety of fields within mathematical and biological sciences.

Avian Immunology

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Publisher : Academic Press
ISBN 13 : 0123972728
Total Pages : 456 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Avian Immunology by : Bernd Kaspers

Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research

Multiscale Cancer Modeling

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Publisher : CRC Press
ISBN 13 : 1439814422
Total Pages : 492 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Multiscale Cancer Modeling by : Thomas S. Deisboeck

Download or read book Multiscale Cancer Modeling written by Thomas S. Deisboeck and published by CRC Press. This book was released on 2010-12-08 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat

Recent Advances in Intelligent Information Systems and Applied Mathematics

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Publisher : Springer Nature
ISBN 13 : 3030341526
Total Pages : 923 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Recent Advances in Intelligent Information Systems and Applied Mathematics by : Oscar Castillo

Download or read book Recent Advances in Intelligent Information Systems and Applied Mathematics written by Oscar Castillo and published by Springer Nature. This book was released on 2020-01-31 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the latest advances in intelligent techniques such as fuzzy logic, neural networks, and optimization algorithms, and their relevance in building intelligent information systems in combination with applied mathematics. The authors also outline the applications of these systems in areas like intelligent control and robotics, pattern recognition, medical diagnosis, time series prediction, and optimization of complex problems. By sharing fresh ideas and identifying new targets/problems it offers young researchers and students new directions for their future research. The book is intended for readers from mathematics and computer science, in particular professors and students working on theory and applications of intelligent systems for real-world applications.

Selected Topics in Cancer Modeling

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Publisher : Springer Science & Business Media
ISBN 13 : 0817647139
Total Pages : 481 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis Selected Topics in Cancer Modeling by : Nicola Bellomo

Download or read book Selected Topics in Cancer Modeling written by Nicola Bellomo and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include stochastic evolutionary models of cancer initiation and progression, tumor cords and their response to anticancer agents, and immune competition in tumor progression and prevention. The complexity of modeling living matter requires the development of new mathematical methods and ideas. This volume, written by first-rate researchers in the field of mathematical biology, is one of the first steps in that direction.

Dynamics of Cancer

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Publisher : Princeton University Press
ISBN 13 : 0691186863
Total Pages : 393 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Dynamics of Cancer by : Steven A. Frank

Download or read book Dynamics of Cancer written by Steven A. Frank and published by Princeton University Press. This book was released on 2018-06-05 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset. The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer. This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.

Philosophy of Cancer

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Publisher : Springer
ISBN 13 : 9402408657
Total Pages : 200 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Philosophy of Cancer by : Marta Bertolaso

Download or read book Philosophy of Cancer written by Marta Bertolaso and published by Springer. This book was released on 2016-08-24 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the increasing complication of models, led to an oscillation between the hectic search of ‘the’ few key factors that cause cancer and the discouragement in face of a seeming ‘endless complexity’. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows limits and possibilities of reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions.

Introduction to Mathematical Oncology

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Publisher : CRC Press
ISBN 13 : 1584889918
Total Pages : 469 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Introduction to Mathematical Oncology by : Yang Kuang

Download or read book Introduction to Mathematical Oncology written by Yang Kuang and published by CRC Press. This book was released on 2016-04-05 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

Guiding Cancer Control

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Publisher : National Academies Press
ISBN 13 : 0309492319
Total Pages : 175 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Guiding Cancer Control by : National Academies of Sciences, Engineering, and Medicine

Download or read book Guiding Cancer Control written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-08-30 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout history, perhaps no other disease has generated the level of social, scientific, and political discourse or has had the degree of cultural significance as cancer. A collective in the truest sense of the word, "cancer" is a clustering of different diseases that afflict individuals in different ways. Its burdens are equally broad and diverse, from the physical, financial, and psychological tolls it imposes on individuals to the costs it inflicts upon the nation's clinical care and public health systems, and despite decades of concerted efforts often referred to as the "war on cancer", those costs have only continued to grow over time. The causes and effects of cancer are complexâ€"in part preventable and treatable, but also in part unknown, and perhaps even unknowable. Guiding Cancer Control defines the key principles, attributes, methods, and tools needed to achieve the goal of implementing an effective national cancer control plan. This report describes the current structure of cancer control from a local to global scale, identifies necessary goals for the system, and formulates the path towards integrated disease control systems and a cancer-free future. This framework is a crucial step in establishing an effective, efficient, and accountable system for controlling cancer and other diseases.

Disease Control Priorities, Third Edition (Volume 6)

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Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Fractals in Biology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 9783764364748
Total Pages : 382 pages
Book Rating : 4.3/5 (647 download)

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Book Synopsis Fractals in Biology and Medicine by : Gabriele A. Losa

Download or read book Fractals in Biology and Medicine written by Gabriele A. Losa and published by Springer Science & Business Media. This book was released on 1994 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: In March 2000 leading scientists gathered at the Centro Seminariale Monte Verità, Ascona, Switzerland, for the Third International Symposium on "Fractals 2000 in Biology and Medicine". This interdisciplinary conference provided stimulating contributions from the very topical field Fractals in Biology and Medicine. This volume highlights the growing power and efficacy of the fractal geometry in understanding how to analyze living phenomena and complex shapes.

Biomat 2015 - International Symposium On Mathematical And Computational Biology

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Publisher : World Scientific
ISBN 13 : 9813141921
Total Pages : 411 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Biomat 2015 - International Symposium On Mathematical And Computational Biology by : Rubem P Mondaini

Download or read book Biomat 2015 - International Symposium On Mathematical And Computational Biology written by Rubem P Mondaini and published by World Scientific. This book was released on 2016-04-28 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book of an international series on interdisciplinary topics of the Mathematical and Biological Sciences. The chapters are related to selected papers on the research themes presented at BIOMAT 2015 International Symposium on Mathematical and Computational Biology which was held in the Roorkee Institute of Technology, in Roorkee, Uttarakhand, India, on November 02-06, 2015. The treatment is both pedagogical and advanced in order to motivate research students to fulfill the requirements of professional practitioners. As in other volumes of this series, there are new important results on the interdisciplinary fields of mathematical and biological sciences and comprehensive reviews written by prominent scientific leaders of famous research groups.There are new results based on the state of art research in Population Dynamics, on Pattern Recognition of Biological Phenomena, the Mathematical Modelling of Infectious Diseases, Computational Biology, the Dynamic and Geometric Modelling of Biological Phenomena, the Modelling of Physiological Disorders, the Optimal Control Techniques in Mathematical Modelling of Biological Phenomena, the Hydrodynamics and Elasticity of Cell Tissues and Bacterial Growth and the Mathematical Morphology of Biological Structures. All these contributions are also strongly recommended to professionals from other scientific areas aiming to work on these interdisciplinary fields.

Theory and Applications of Hopf Bifurcation

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Publisher : CUP Archive
ISBN 13 : 9780521231589
Total Pages : 324 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis Theory and Applications of Hopf Bifurcation by : B. D. Hassard

Download or read book Theory and Applications of Hopf Bifurcation written by B. D. Hassard and published by CUP Archive. This book was released on 1981-02-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text will be of value to all those interested in and studying the subject in the mathematical, natural and engineering sciences.