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A Primer On Bayesian Statistics In Health Economics And Outcomes Research
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Book Synopsis Bayesian Methods in Health Economics by : Gianluca Baio
Download or read book Bayesian Methods in Health Economics written by Gianluca Baio and published by CRC Press. This book was released on 2012-11-12 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian statistics using accessible mathematics. The next chapters describe the theory and practice of cost-effectiveness analysis from a statistical viewpoint, and Bayesian computation, notably MCMC. The final chapter presents three detailed case studies covering cost-effectiveness analyses using individual data from clinical trials, evidence synthesis and hierarchical models and Markov models. The text uses WinBUGS and JAGS with datasets and code available online.
Book Synopsis A Primer on Bayesian Statistics in Health Economics and Outcomes Research by : Bryan Luce
Download or read book A Primer on Bayesian Statistics in Health Economics and Outcomes Research written by Bryan Luce and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bayesian Cost-Effectiveness Analysis of Medical Treatments by : Elias Moreno
Download or read book Bayesian Cost-Effectiveness Analysis of Medical Treatments written by Elias Moreno and published by CRC Press. This book was released on 2019-01-30 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cost-effectiveness analysis is becoming an increasingly important tool for decision making in the health systems. Cost-Effectiveness of Medical Treatments formulates the cost-effectiveness analysis as a statistical decision problem, identifies the sources of uncertainty of the problem, and gives an overview of the frequentist and Bayesian statistical approaches for decision making. Basic notions on decision theory such as space of decisions, space of nature, utility function of a decision and optimal decisions, are explained in detail using easy to read mathematics. Features Focuses on cost-effectiveness analysis as a statistical decision problem and applies the well-established optimal statistical decision methodology. Discusses utility functions for cost-effectiveness analysis. Enlarges the class of models typically used in cost-effectiveness analysis with the incorporation of linear models to account for covariates of the patients. This permits the formulation of the group (or subgroup) theory. Provides Bayesian procedures to account for model uncertainty in variable selection for linear models and in clustering for models for heterogeneous data. Model uncertainty in cost-effectiveness analysis has not been considered in the literature. Illustrates examples with real data. In order to facilitate the practical implementation of real datasets, provides the codes in Mathematica for the proposed methodology. The motivation for the book is to make the achievements in cost-effectiveness analysis accessible to health providers, who need to make optimal decisions, to the practitioners and to the students of health sciences. Elías Moreno is Professor of Statistics and Operational Research at the University of Granada, Spain, Corresponding Member of the Royal Academy of Sciences of Spain, and elect member of ISI. Francisco José Vázquez-Polo is Professor of Mathematics and Bayesian Methods at the University of Las Palmas de Gran Canaria, and Head of the Department of Quantitative Methods. Miguel Ángel Negrín is Senior Lecturer in the Department of Quantitative Methods at the ULPGC. His main research topics are Bayesian methods applied to Health Economics, economic evaluation and cost-effectiveness analysis, meta-analysis and equity in the provision of healthcare services.
Book Synopsis The Oxford Handbook of Health Economics by : Sherry Glied
Download or read book The Oxford Handbook of Health Economics written by Sherry Glied and published by OUP Oxford. This book was released on 2013-05-23 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbook of Health Economics provides an accessible and authoritative guide to health economics, intended for scholars and students in the field, as well as those in adjacent disciplines including health policy and clinical medicine. The chapters stress the direct impact of health economics reasoning on policy and practice, offering readers an introduction to the potential reach of the discipline. Contributions come from internationally-recognized leaders in health economics and reflect the worldwide reach of the discipline. Authoritative, but non-technical, the chapters place great emphasis on the connections between theory and policy-making, and develop the contributions of health economics to problems arising in a variety of institutional contexts, from primary care to the operations of health insurers. The volume addresses policy concerns relevant to health systems in both developed and developing countries. It takes a broad perspective, with relevance to systems with single or multi-payer health insurance arrangements, and to those relying predominantly on user charges; contributions are also included that focus both on medical care and on non-medical factors that affect health. Each chapter provides a succinct summary of the current state of economic thinking in a given area, as well as the author's unique perspective on issues that remain open to debate. The volume presents a view of health economics as a vibrant and continually advancing field, highlighting ongoing challenges and pointing to new directions for further progress.
Book Synopsis Bayesian Approaches to Clinical Trials and Health-Care Evaluation by : David J. Spiegelhalter
Download or read book Bayesian Approaches to Clinical Trials and Health-Care Evaluation written by David J. Spiegelhalter and published by John Wiley & Sons. This book was released on 2004-01-16 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basics to more advanced techniques. Illustrated throughout by detailed case studies and worked examples Includes exercises in all chapters Accessible to anyone with a basic knowledge of statistics Authors are at the forefront of research into Bayesian methods in medical research Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.
Book Synopsis A Mathematical Primer for Social Statistics by : John Fox
Download or read book A Mathematical Primer for Social Statistics written by John Fox and published by SAGE Publications. This book was released on 2021-01-11 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Mathematical Primer for Social Statistics, Second Edition presents mathematics central to learning and understanding statistical methods beyond the introductory level: the basic "language" of matrices and linear algebra and its visual representation, vector geometry; differential and integral calculus; probability theory; common probability distributions; statistical estimation and inference, including likelihood-based and Bayesian methods. The volume concludes by applying mathematical concepts and operations to a familiar case, linear least-squares regression. The Second Edition pays more attention to visualization, including the elliptical geometry of quadratic forms and its application to statistics. It also covers some new topics, such as an introduction to Markov-Chain Monte Carlo methods, which are important in modern Bayesian statistics. A companion website includes materials that enable readers to use the R statistical computing environment to reproduce and explore computations and visualizations presented in the text. The book is an excellent companion to a "math camp" or a course designed to provide foundational mathematics needed to understand relatively advanced statistical methods.
Book Synopsis The Theory That Would Not Die by : Sharon Bertsch McGrayne
Download or read book The Theory That Would Not Die written by Sharon Bertsch McGrayne and published by Yale University Press. This book was released on 2011-05-17 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This account of how a once reviled theory, Baye’s rule, came to underpin modern life is both approachable and engrossing" (Sunday Times). A New York Times Book Review Editors’ Choice Bayes' rule appears to be a straightforward, one-line theorem: by updating our initial beliefs with objective new information, we get a new and improved belief. To its adherents, it is an elegant statement about learning from experience. To its opponents, it is subjectivity run amok. In the first-ever account of Bayes' rule for general readers, Sharon Bertsch McGrayne explores this controversial theorem and the generations-long human drama surrounding it. McGrayne traces the rule’s discovery by an 18th century amateur mathematician through its development by French scientist Pierre Simon Laplace. She reveals why respected statisticians rendered it professionally taboo for 150 years—while practitioners relied on it to solve crises involving great uncertainty and scanty information, such as Alan Turing's work breaking Germany's Enigma code during World War II. McGrayne also explains how the advent of computer technology in the 1980s proved to be a game-changer. Today, Bayes' rule is used everywhere from DNA de-coding to Homeland Security. Drawing on primary source material and interviews with statisticians and other scientists, The Theory That Would Not Die is the riveting account of how a seemingly simple theorem ignited one of the greatest controversies of all time.
Book Synopsis Decision Modelling for Health Economic Evaluation by : Andrew Briggs
Download or read book Decision Modelling for Health Economic Evaluation written by Andrew Briggs and published by OUP Oxford. This book was released on 2006-08-17 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In financially constrained health systems across the world, increasing emphasis is being placed on the ability to demonstrate that health care interventions are not only effective, but also cost-effective. This book deals with decision modelling techniques that can be used to estimate the value for money of various interventions including medical devices, surgical procedures, diagnostic technologies, and pharmaceuticals. Particular emphasis is placed on the importance of the appropriate representation of uncertainty in the evaluative process and the implication this uncertainty has for decision making and the need for future research. This highly practical guide takes the reader through the key principles and approaches of modelling techniques. It begins with the basics of constructing different forms of the model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a valuable tool for informing future research exercises. Case studies and exercises are supported with online templates and solutions. This book will help analysts understand the contribution of decision-analytic modelling to the evaluation of health care programmes. ABOUT THE SERIES: Economic evaluation of health interventions is a growing specialist field, and this series of practical handbooks will tackle, in-depth, topics superficially addressed in more general health economics books. Each volume will include illustrative material, case histories and worked examples to encourage the reader to apply the methods discussed, with supporting material provided online. This series is aimed at health economists in academia, the pharmaceutical industry and the health sector, those on advanced health economics courses, and health researchers in associated fields.
Book Synopsis Evidence Synthesis for Decision Making in Healthcare by : Nicky J. Welton
Download or read book Evidence Synthesis for Decision Making in Healthcare written by Nicky J. Welton and published by John Wiley & Sons. This book was released on 2012-04-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease progression, and epidemiology models). A comprehensive, coherent framework is adopted and estimated using Bayesian methods. Key features: A coherent approach to evidence synthesis from multiple sources. Focus is given to Bayesian methods for evidence synthesis that can be integrated within cost-effectiveness analyses in a probabilistic framework using Markov Chain Monte Carlo simulation. Provides methods to statistically combine evidence from a range of evidence structures. Emphasizes the importance of model critique and checking for evidence consistency. Presents numerous worked examples, exercises and solutions drawn from a variety of medical disciplines throughout the book. WinBUGS code is provided for all examples. Evidence Synthesis for Decision Making in Healthcare is intended for health economists, decision modelers, statisticians and others involved in evidence synthesis, health technology assessment, and economic evaluation of health technologies.
Book Synopsis Best Practices in Quantitative Methods by : Jason W. Osborne
Download or read book Best Practices in Quantitative Methods written by Jason W. Osborne and published by SAGE. This book was released on 2008 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to Best Practices in Quantitative Methods envision quantitative methods in the 21st century, identify the best practices, and, where possible, demonstrate the superiority of their recommendations empirically. Editor Jason W. Osborne designed this book with the goal of providing readers with the most effective, evidence-based, modern quantitative methods and quantitative data analysis across the social and behavioral sciences. The text is divided into five main sections covering select best practices in Measurement, Research Design, Basics of Data Analysis, Quantitative Methods, and Advanced Quantitative Methods. Each chapter contains a current and expansive review of the literature, a case for best practices in terms of method, outcomes, inferences, etc., and broad-ranging examples along with any empirical evidence to show why certain techniques are better. Key Features: Describes important implicit knowledge to readers: The chapters in this volume explain the important details of seemingly mundane aspects of quantitative research, making them accessible to readers and demonstrating why it is important to pay attention to these details. Compares and contrasts analytic techniques: The book examines instances where there are multiple options for doing things, and make recommendations as to what is the "best" choice—or choices, as what is best often depends on the circumstances. Offers new procedures to update and explicate traditional techniques: The featured scholars present and explain new options for data analysis, discussing the advantages and disadvantages of the new procedures in depth, describing how to perform them, and demonstrating their use. Intended Audience: Representing the vanguard of research methods for the 21st century, this book is an invaluable resource for graduate students and researchers who want a comprehensive, authoritative resource for practical and sound advice from leading experts in quantitative methods.
Book Synopsis Applying Social Science by : David Byrne
Download or read book Applying Social Science written by David Byrne and published by Policy Press. This book was released on 2011-02-16 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book examines how social science is applied now and how it might be applied in the future in relation to social transformation in a time of crisis.
Book Synopsis Bubbles and Contagion in Financial Markets, Volume 2 by : Eva R. Porras
Download or read book Bubbles and Contagion in Financial Markets, Volume 2 written by Eva R. Porras and published by Springer. This book was released on 2017-10-31 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on extending the models and theories (from a mathematical/statistical point of view) which were introduced in the first volume to a more technical level. Where volume I provided an introduction to the mathematics of bubbles and contagion, volume II digs far more deeply and widely into the modeling aspects.
Download or read book Precision Cosmology written by and published by Cambridge University Press. This book was released on with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Statistical Issues in Drug Development by : Stephen S. Senn
Download or read book Statistical Issues in Drug Development written by Stephen S. Senn and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and interpretation ofclinical trials. Expanded sections on missing data, equivalence, meta-analysisand dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage ofpharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9,Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue betweenstatisticians and life scientists working within the pharmaceuticalindustry. The accessible and wide-ranging coverage make itessential reading for both statisticians and non-statisticiansworking in the pharmaceutical industry, regulatory bodies andmedical research institutes. There is also much to benefitundergraduate and postgraduate students whose courses include amedical statistics component.
Book Synopsis Handbook of Health Economics by : Mark V. Pauly
Download or read book Handbook of Health Economics written by Mark V. Pauly and published by Elsevier. This book was released on 2012-01-05 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: "As a relatively new subdiscipline of economics, health economics has made many contributions to areas of the main discipline, such as insurance economics. This volume provides a survey of the burgeoning literature on the subject of health economics." {source : site de l'éditeur].
Book Synopsis Strategies for Quantitative Research by : Grant S. McCall
Download or read book Strategies for Quantitative Research written by Grant S. McCall and published by Routledge. This book was released on 2018-02-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is little secret that most archaeologists are uneasy with statistics. Thankfully, in the modern world, quantitative analysis has been made immensely easier by statistical software packages. Software now does virtually all our statistical calculations, removing a great burden for researchers. At the same time, since most statistical analysis now takes place through the pushing of buttons in software packages, new problems and dangers have emerged. How does one know which statistical test to use? How can one tell if certain data violate the assumptions of a particular statistical analysis? Rather than focusing on the mathematics of calculation, this concise handbook selects appropriate forms of analysis and explains the assumptions that underlie them. It deals with fundamental issues, such as what kinds of data are common in the field of archaeology and what are the goals of various forms of analysis. This accessible textbook lends a refreshing playfulness to an often-humorless subject and will be enjoyed by students and professionals alike.
Book Synopsis Methods for the Economic Evaluation of Health Care Programmes by : M. F. Drummond
Download or read book Methods for the Economic Evaluation of Health Care Programmes written by M. F. Drummond and published by . This book was released on 2005 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly successful textbook Methods for the Economic Evaluation of Health Care is now available in its third edition. Over the years it has become the standard textbook in the field world-wide. It mirrors the huge expansion of the field of economic evaluation in health care. This new edition builds on the strengths of previous editions being clearly written in a style accessible to a wide readership. Key methodological principles are outlined using a critical appraisal checklist that can be applied to any published study. The methodological features of the basic forms of analysis are then explained in more detail with special emphasis of the latest views on productivity costs, the characterization of uncertainty and the concept of net benefit. The book has been greatly revised and expanded especially concerning analyzing patient-level data and decision-analytic modeling. There is discussion of new methodological approaches, including cost effectiveness acceptability curves, net benefit regression, probalistic sensitivity analysis and value of information analysis. There is an expanded chapter on the use of economic evaluation, including discussion of the use of cost-effectiveness thresholds, equity considerations and the transferability of economic data. This new edition is required for anyone commissioning, undertaking or using economic evaluations in health care, and will be popular with health service professionals, health economists, pharmacists and health care decision makers. It is especially relevant for those taking pharmacoeconomics courses.
