A Modern Approach To Biofilm Related Orthopaedic Implant Infections

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A Modern Approach to Biofilm-Related Orthopaedic Implant Infections

Author : Lorenzo Drago
Publisher : Springer
ISBN 13 : 3319522744
Total Pages : 120 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis A Modern Approach to Biofilm-Related Orthopaedic Implant Infections by : Lorenzo Drago

Download or read book A Modern Approach to Biofilm-Related Orthopaedic Implant Infections written by Lorenzo Drago and published by Springer. This book was released on 2017-05-16 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the potential causes of these infections, provides sound diagnostic criteria guidelines, and explains how these prosthetic infections are managed from orthopedic surgery, clinical and diagnostic perspectives. PJI can lead to multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1–2% after primary total hip and knee arthroplasty and account for approximately 7–12% of all revision cases. Orthopedic hardware infections are much-feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to higher morbidity, it is important to understand their pathophysiology and the principles behind their diagnosis and initial treatment. The pathogenesis of these kinds of infections is intimately connected to the biofilm-producing trait characteristic of many microorganisms, which can have a critical effect on the likely success of treatments. The book offers a unique guide for all scientists working in arthroplasty who are seeking an update on the field, and for newcomers alike.

Microbial Biofilms in Chronic and Recurrent Infections

Author : Axel Cloeckaert
Publisher : Frontiers Media SA
ISBN 13 : 2889740994
Total Pages : 134 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Microbial Biofilms in Chronic and Recurrent Infections by : Axel Cloeckaert

Download or read book Microbial Biofilms in Chronic and Recurrent Infections written by Axel Cloeckaert and published by Frontiers Media SA. This book was released on 2022-01-19 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prosthetic Joint Infections

Author : Trisha Peel
Publisher : Springer
ISBN 13 : 3319652508
Total Pages : 270 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Prosthetic Joint Infections by : Trisha Peel

Download or read book Prosthetic Joint Infections written by Trisha Peel and published by Springer. This book was released on 2017-11-28 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Musculoskeletal Infection

Author : Melanie Coathup
Publisher : Springer Nature
ISBN 13 : 3030832511
Total Pages : 378 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Musculoskeletal Infection by : Melanie Coathup

Download or read book Musculoskeletal Infection written by Melanie Coathup and published by Springer Nature. This book was released on 2022-02-01 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers international knowledge and contemporary clinical and scientific evidence on infections associated with the musculoskeletal system at a time when we are confronted with significant challenges and uncertainty. A key focus of the book is enhancing and advancing future discovery in the detection, prevention and treatment of musculoskeletal infection. This is an ideal book for physicians, surgeons, research scientists, university students, as well as medical and allied health students.

Management of Periprosthetic Joint Infections (PJIs)

Author : J.J. Chris Arts
Publisher : Woodhead Publishing
ISBN 13 : 0081002424
Total Pages : 306 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Management of Periprosthetic Joint Infections (PJIs) by : J.J. Chris Arts

Download or read book Management of Periprosthetic Joint Infections (PJIs) written by J.J. Chris Arts and published by Woodhead Publishing. This book was released on 2016-10-25 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies. Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections. - Provides essential background knowledge on the mechanisms and identification of PJIs - Dedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the body - Contains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage

Feigin and Cherry's Textbook of Pediatric Infectious Diseases - E-Book

Author : James Cherry
Publisher : Elsevier Health Sciences
ISBN 13 : 0323827640
Total Pages : 14152 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Feigin and Cherry's Textbook of Pediatric Infectious Diseases - E-Book by : James Cherry

Download or read book Feigin and Cherry's Textbook of Pediatric Infectious Diseases - E-Book written by James Cherry and published by Elsevier Health Sciences. This book was released on 2024-08-29 with total page 14152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely considered the premier text in pediatric infectious diseases, Feigin and Cherry's Textbook of Pediatric Infectious Diseases, 9th Edition, provides authoritative, up-to-date coverage of this rapidly changing field. Extensively revised by Drs. James Cherry, Sheldon L. Kaplan, Gail J. Demmler-Harrison, William J. Steinbach, Peter J. Hotez, and new editor John V. Williams, this two-volume reference delivers the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. It serves as a reliable, everyday resource for practicing ID specialists, and an invaluable reference for medical students, residents, and fellows in ID, pediatricians and internists, and others who work with neonates, children, and adolescents or in public health. - Discusses infectious diseases according to organ systems that may be affected, as well as individually by microorganisms, placing emphasis on clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Includes expanded information on Q fever, antibiotic resistance and antibiotic agents, human coronaviruses, pox viruses, and infections in the compromised host, and contains new COVID-19 content across numerous chapters. - Features a new chapter on antimicrobial stewardship, and new coverage of antivirals for pox viruses. - Reflects today's more aggressive infectious and antibiotic-resistant organisms as well as emerging and re-emerging infectious diseases. - Contains hundreds of full-color images (many are new!), including clinical photos, radiographic images, drawings, charts, and graphs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Additional digital ancillary content may publish up to 6 weeks following the publication date. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Bone and Joint Infections

Author : W. Zimmerli
Publisher : John Wiley & Sons
ISBN 13 : 1118581776
Total Pages : 429 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Bone and Joint Infections by : W. Zimmerli

Download or read book Bone and Joint Infections written by W. Zimmerli and published by John Wiley & Sons. This book was released on 2015-01-27 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.

Biofilm Infections

Author : Thomas Bjarnsholt
Publisher : Springer
ISBN 13 : 9781489982285
Total Pages : 0 pages
Book Rating : 4.9/5 (822 download)

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Book Synopsis Biofilm Infections by : Thomas Bjarnsholt

Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Tissue Engineering Using Ceramics and Polymers

Author : Aldo R. Boccaccini
Publisher : Woodhead Publishing
ISBN 13 : 0128205792
Total Pages : 890 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Tissue Engineering Using Ceramics and Polymers by : Aldo R. Boccaccini

Download or read book Tissue Engineering Using Ceramics and Polymers written by Aldo R. Boccaccini and published by Woodhead Publishing. This book was released on 2021-10-27 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Engineering Using Ceramics and Polymers, Third Edition is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction, repair and organ regeneration. With its distinguished editors and international team of contributors, this book reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. New sections cover nanobiomaterials, drug delivery, advanced imaging and MRI for tissue engineering, and characterization of vascularized scaffolds. Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated with the aid of biomaterials. - Provides updated and new information on ceramic and polymer biomaterials for tissue engineering - Presents readers with systematic coverage of the processing, characterization and modeling of each material - Includes content that will be relevant to a range of readers, including biomedical engineers, materials scientists, and those interested in regenerative medicine

Orthopedic Infection

Author : David Schlossberg
Publisher : Springer Science & Business Media
ISBN 13 : 1461238706
Total Pages : 196 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Orthopedic Infection by : David Schlossberg

Download or read book Orthopedic Infection written by David Schlossberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, clinically oriented reference details the state-of-the-art approach to infections of bones and joints. Utility for all practitioners is ensured by the wide range of contributors who include infectious disease specialists, rheumatologists, orthopedic surgeons, and radiologists. This is the definitive resource for the clinician who treats orthopedic infections.

Regenerative Medicine and Plastic Surgery

Author : Dominik Duscher
Publisher : Springer Nature
ISBN 13 : 3030199584
Total Pages : 466 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Regenerative Medicine and Plastic Surgery by : Dominik Duscher

Download or read book Regenerative Medicine and Plastic Surgery written by Dominik Duscher and published by Springer Nature. This book was released on 2019-11-26 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the current research concepts and the emerging technologies in the field of stem cells and tissue engineering. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner. Divided into five parts, the book opens with a description of the elements of regenerative medicine including definitions, basic principles of soft and bone tissue regeneration, biomaterials and scaffolds. Current research concepts are explored in the second part of this book, for example mechanotransduction and the utility of extracellular vesicles. In the third part, the editors present the emerging technologies and highlight the novel perspectives on bionic reconstruction and biomimetics in surgery and regenerative medicine. Part four deals with translational aspects including practical information on moving scientific findings from bench to bedside. The final part then describes in detail applications in clinical plastic surgery. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "In your hands is a comprehensive encyclopedia of two rapidly converging fields. Drs Duscher and Shiffman have done an outstanding job of highlighting the interdependent relationship between plastic surgery and regenerative medicine. Ultimately, this is to the benefit of both fields." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Biofilms and Implantable Medical Devices

Author : Ying Deng
Publisher : Woodhead Publishing
ISBN 13 : 0081003986
Total Pages : 240 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Biofilms and Implantable Medical Devices by : Ying Deng

Download or read book Biofilms and Implantable Medical Devices written by Ying Deng and published by Woodhead Publishing. This book was released on 2016-10-24 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. - Provides useful information on the fundamentals of biofilm problems in medical devices - Discusses biofilm problems in a range of medical devices - Focuses on strategies for prevention of biofilm formation

Phage Therapy: A Practical Approach

Author : Andrzej Górski
Publisher : Springer Nature
ISBN 13 : 3030267369
Total Pages : 384 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Phage Therapy: A Practical Approach by : Andrzej Górski

Download or read book Phage Therapy: A Practical Approach written by Andrzej Górski and published by Springer Nature. This book was released on 2019-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a detailed yet clear insight into the current state of the art of the therapeutic application of bacteriophages in different conditions. The authors bring in their practical expertise within their respective fields of expertise and provide an excellent overview of the potential and actual use of phage therapy. Topics like economic feasibility compared to traditional antibiotics and also regulatory issues are discussed in far detail. This new volume is therefore a valuable resource for individuals engaged in the medical application of novel phage therapies.

The Application of Bioactive Materials in Bone Repair

Author : Hu Yan
Publisher : Frontiers Media SA
ISBN 13 : 2832556736
Total Pages : 203 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Application of Bioactive Materials in Bone Repair by : Hu Yan

Download or read book The Application of Bioactive Materials in Bone Repair written by Hu Yan and published by Frontiers Media SA. This book was released on 2024-11-12 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological activity, in the field of materials, mainly refers to the properties that can induce special biological and chemical reactions at the interface between materials and biological tissues, forming chemical bonds between materials and biological tissues. A bioactive material is a biomaterial that is able to participate in a regenerative process at the molecular level and dictate molecular and cellular events in a preferred and predictable way. In the process of biomineralization, the ability of biological material to chemically bond with living bone is an important index of the biomaterial, and the biological activity of the material in vivo is reflected by the simulated body fluid-SBF ability of apatite formed on the surface of the material. In the field of bone repair, bioactive materials such as hydrogels, agglomerates, and magnetic nanoparticles are playing an increasingly important role. Compared with traditional bone repair materials, bioactive materials have many advantages, such as high biocompatibility, simulation of the extracellular environment, and easy engineering modification. In addition, as a delivery system, bioactive materials are modified and engineered to be minimally invasive, targeted, and sustainably released. The above characteristics have important application value in the field of bone repair.

Culture Negative Orthopedic Biofilm Infections

Author : Garth D. Ehrlich
Publisher : Springer Science & Business Media
ISBN 13 : 3642295541
Total Pages : 148 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Culture Negative Orthopedic Biofilm Infections by : Garth D. Ehrlich

Download or read book Culture Negative Orthopedic Biofilm Infections written by Garth D. Ehrlich and published by Springer Science & Business Media. This book was released on 2012-12-18 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiological sterility in which modern molecular methods would be expected to find bacterial DNA, RNA-based microscopic methods would be expected to locate bacterial cells, and cultures would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical group in which current strategies are based on the meticulous removal of compromised tissues, antibiotic options as based on high biofilm-killing local doses, and there are practical bedside strategies for dealing with biofilm infections. So here is where the new paradigm of biofilm infection meets the equally new paradigm of the culture negativity of biofilms, and this volume presents a conceptual synthesis that may soon combine the most effective molecular methods for the detection and identification of bacteria with a surgical discipline that is ready to help patients.

The Microbiology of Skin, Soft Tissue, Bone and Joint Infections

Author : Kateryna Kon
Publisher : Academic Press
ISBN 13 : 0128110937
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Microbiology of Skin, Soft Tissue, Bone and Joint Infections by : Kateryna Kon

Download or read book The Microbiology of Skin, Soft Tissue, Bone and Joint Infections written by Kateryna Kon and published by Academic Press. This book was released on 2017-04-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Microbiology of Skin, Soft Tissue, Bone and Joint Infections: Volume 2 discusses modern approaches in diagnosis, treatment, and prophylaxis of skin, soft tissue, bone, and joint infections. The volume has been divided into three sections. The first section includes chapters on diagnosis, treatment, and prophylaxis of skin and soft tissue infections. It discusses antimicrobial and surgical treatment of wounds, diabetic foot, and different soft tissue infections. Ten chapters are devoted to cutaneous and musculoskeletal infections in special groups of patients, which have their own specificity, i.e. in pediatric and HIV-infected patients. Together with chapters on commonly present diseases, there are chapters which discuss interesting but not well studied pathologies (natal cleft pilonidal sinus) and pathogens (Malassezia and Shewanella spp.). The second section reviews etiology, pathogenesis, diagnosis and treatment of bone and joint infections, mainly osteomyelitis and prosthetic joint infections. Also, one chapter in this section discusses a newly emerging bacterial pathogen that causes skeletal infections, Kingella kingae. The third section incorporates alternative and new approaches—such as nanotechnology, ultrasound, novel delivery approaches and phyto-derived medicines—to the treatment and prophylaxis of skin, soft tissue, bone, and joint infections. - Encompasses a broad range of skin, soft tissue, bone, and joint infections, including questions of etiology, pathogenesis, diagnosis, prognosis, treatment, and prophylaxis - Written by highly professional and eminent surgeons, microbiologists, and infectious disease specialists - Discusses topics using modern insight, providing all necessary scientific information on each aspect - Includes scientific understanding and practical guidelines, which make it interesting for both research scientists and practitioners working with skin, soft tissue, bone, and joint infections

Racing for the Surface

Author : Bingyun Li
Publisher : Springer Nature
ISBN 13 : 3030344754
Total Pages : 648 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Racing for the Surface by : Bingyun Li

Download or read book Racing for the Surface written by Bingyun Li and published by Springer Nature. This book was released on 2020-03-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.