A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES.

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. by :

Download or read book A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: BackgroundDespite new technology developed for diabetes management, glucose control remains suboptimal especially during meals. In recent years, bioelectronic medicine has shown promise for management of glucose fluctuations by controlling the insulin sensitivity (SI) through modulation of neural pathways. Within this context, in this work we present a proof-of-concept of the first closed-loop system that incorporates SI as an additional control variable for glucose regulation. MethodThe coordinated bi-hormonal bio-inspired controller (BiAP) for type 1 diabetes mellitus (T1DM) was extended by including a standard proportional-derivative (sPD) controller to determine the optimal SI from continuous blood glucose measurements. The tuning of the parameters of the resulting hybrid hormonal-insulin sensitivity glucose (InSiG) controller, and a comparison in performance with BiAP, were carried out on a virtual population of subjects with T1DM (n=20, 10 adults and 10 adolescents). A statistical analysis of the differences between controllers was performed using the parametric student paired t-test (u03b1 = 0.01). ResultsInSiG significantly increased the percentage of time glucose levels were within target (70-180 md/dL) to 99.4u00b11.0% in adults and 96.4u00b14.6% in adolescents (p

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach

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Publisher : Academic Press
ISBN 13 : 0323907776
Total Pages : 164 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach by : Anirudh Nath

Download or read book Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach written by Anirudh Nath and published by Academic Press. This book was released on 2022-08-13 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult. Presents control-oriented modeling of the gluco-regulatory system of Type 1 diabetic patients using input-output data Demonstrates the design of a robust insulin delivery mechanism utilizing state estimation information with parametric uncertainties and exogenous disturbance in the framework of Linear Matrix Inequality (LMI) Introduces readers to the relevance and effectiveness of powerful nonlinear controllers for the Artificial Pancreas Provides the first book on LMI-based nonlinear control techniques for the Artificial Pancreas

Closed-Loop Control of Blood Glucose

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Publisher : Springer
ISBN 13 : 3540740317
Total Pages : 167 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Closed-Loop Control of Blood Glucose by : Frederick Chee

Download or read book Closed-Loop Control of Blood Glucose written by Frederick Chee and published by Springer. This book was released on 2007-10-24 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents closed-loop blood glucose control in a simple manner, which includes the hardware and "software" components that make up the control system. It provides examples on how mathematical models are formulated as well as the control algorithms that stem from mathematical exercises. The book also describes the basic physiology of blood glucose regulation during fasting and meal from a functional level.

Functional Insulin Treatment

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Publisher : Springer Science & Business Media
ISBN 13 : 3642972985
Total Pages : 159 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Functional Insulin Treatment by : Kinga Howorka

Download or read book Functional Insulin Treatment written by Kinga Howorka and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Insulin Treatment (FIT) is the most effective method of treatmentfor type 1 (insulin-dependent) diabetes available today. Whether with an insulin pump or with mul- tiple daily injections, the diabetic patient trained in FIT is able to dose his insulin on the basis of actual fuction so that he achieves near-normoglycemia and the freedom to eat when, what and how much he wants. Previous diabetes eduction programs have adaped the patient's lifestyle to the conditions of therapy. The goal ofFIT is to adapt the therapy to the lifestyle of the pa- tient. Combined withthe opportunity for active and respon- sible patient participation, this flexibility has an enor- mous positive effect on the patient's long-term motivation. This book creates a common basis for communication among therapists (physicians, nurses, dietitians, diabetes educa- tors) and patients involved in FIT. It clearly defines the principles of the treatment and describes the contents, media and techniques of a practical program for training patients to carry it out. The reader is given a clear pictureof just what knowledge and skills the patient needs - and how to help him acquire them - in order to attain the twin goals of excellent metabolic control and flexible life- style.

Practical Insulin

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Publisher : American Diabetes Association
ISBN 13 : 1580405819
Total Pages : 74 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Practical Insulin by : American Diabetes Association

Download or read book Practical Insulin written by American Diabetes Association and published by American Diabetes Association. This book was released on 2015-07-14 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of Practical Insulin: A Handbook for Prescribing Providers is a completely revised version of the popular ADA pocket reference. With information on all the currently FDA-approved insulins, this handy pocket guide gives you fast, reliable information and helps you overcome the challenges all clinicians face—choosing an insulin regimen to effectively manage blood glucose and patient resistance. It includes data on all types of insulin, mixing insulins, absorption rates, and more.

Insulin Pumps and Continuous Glucose Monitoring

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Publisher : American Diabetes Association
ISBN 13 : 1580407196
Total Pages : 219 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Insulin Pumps and Continuous Glucose Monitoring by : Francine R. Kaufman

Download or read book Insulin Pumps and Continuous Glucose Monitoring written by Francine R. Kaufman and published by American Diabetes Association. This book was released on 2017-11-08 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being diagnosed with diabetes, no longer means giving up an active life. New technology, such as insulin pumps and continuous glucose monitors, can help people with both type 1 and type 2 diabetes stay active and flexible and maintain healthy attitudes and lifestyles. Designed to mimic the action of the pancreas, insulin pumps are small, pager-sized devices that infuse insulin under the skin based on programmed rates. Not only does this eliminate the need for injections, it also allows for small amounts of insulin to to be released throughout the day, and large amounts to be administered at meals based on what's being eaten. When paired with a continuous glucose monitor, which provides a continuous readout of glucose levels, users can enjoy accurate, tight glucose control that provides much greater flexibility and freedom than the old check-and-inject method. Dr. Francine Kaufman's Insulin Pumps and Continuous Glucose Monitoring explains the advances in glucose management, and thoroughly discusses the technology, as well as the physical and psychological aspects of diabetes care. It provides a comprehensive medical approach toward diabetes management and pump therapy with an appreciation of the real-life challenges and frustrations faced every day by people with diabetes.

Mechanisms of Insulin Action

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Publisher : Springer Science & Business Media
ISBN 13 : 0387722041
Total Pages : 223 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel

Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Artificial Systems for Insulin Delivery

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ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Artificial Systems for Insulin Delivery by : Paolo Brunetti

Download or read book Artificial Systems for Insulin Delivery written by Paolo Brunetti and published by . This book was released on 1983 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Robust Model-based Control of Blood Glucose Concentration in Type 1 Diabetic Patients

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Publisher :
ISBN 13 : 9783990332580
Total Pages : 176 pages
Book Rating : 4.3/5 (325 download)

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Book Synopsis Robust Model-based Control of Blood Glucose Concentration in Type 1 Diabetic Patients by : Harald Kirchsteiger

Download or read book Robust Model-based Control of Blood Glucose Concentration in Type 1 Diabetic Patients written by Harald Kirchsteiger and published by . This book was released on 2012 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Insulin resistance and pre-diabetes

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ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Insulin resistance and pre-diabetes by :

Download or read book Insulin resistance and pre-diabetes written by and published by . This book was released on 2003 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease

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Publisher : Academic Press
ISBN 13 : 0128221941
Total Pages : 475 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease by : Asim K. Duttaroy

Download or read book Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease written by Asim K. Duttaroy and published by Academic Press. This book was released on 2021-07-08 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease explores a wide range of studies from clinical investigations to mechanistic research, covering the actions of bioactives on specific tissues and cells in intestinal, neurological, immunological and cardiovascular health and disease, including cancers. The book also focuses on metabolism, mechanisms of actions, tissue-specific effects, and the structure–function relationships between clinical trial, ex vivo and in vitro data. Written for nutrition researchers, clinical researchers, dieticians, and others working in and studying health-related fields, this book highlights the concepts surrounding the preventive and therapeutic impacts of bioactive foods. Presents information on the prevention of disease using bioactive compounds Consolidates the research outcome from a variety of sources on specific bioactive foods Contains coverage of bioactive lipids and lipid mediators, bioactive phytochemicals, probiotics, bioactive proteins, peptides, polysaccharides, fibers and sphingolipids

Research Awards Index

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ISBN 13 :
Total Pages : 1436 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1985 with total page 1436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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ISBN 13 :
Total Pages : 2036 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Textbook of Natural Medicine - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455740144
Total Pages : 1944 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Textbook of Natural Medicine - E-Book by : Joseph E. Pizzorno

Download or read book Textbook of Natural Medicine - E-Book written by Joseph E. Pizzorno and published by Elsevier Health Sciences. This book was released on 2012-09-09 with total page 1944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering preventive, non-invasive, and natural treatments, Textbook of Natural Medicine, 4th Edition offers more than just alternative medicine. It promotes an integrated practice that can utilize natural medicine, traditional Western medicine, or a combination of both in a comprehensive, scientific treatment plan. Based on a combination of philosophy and clinical studies, Textbook of Natural Medicine helps you provide health care that identifies and controls the underlying causes of disease, is supportive of the body's own healing processes, and is considerate of each patient's unique biochemistry. Internationally known authors Joseph Pizzorno and Michael Murray include detailed pharmacologic information on herbs and supplements, plus evidence-based coverage of diseases and conditions to help you make accurate diagnoses and provide effective therapy. Comprehensive, unique coverage makes this book the gold standard in natural medicine. A scientific presentation includes the science behind concepts and treatments, and discusses Western medical treatments and how they can work with natural medicine in a comprehensive treatment plan; if natural medicine is not effective, this book recommends the Western treatment. Coverage of pharmacology of natural medicines includes the uses and potential dangers of nearly 80 herbal medicines, special nutrients, and other natural agents, addressing topics such as general information, chemical composition, history, pharmacology, clinical applications dosage, and toxicology. In-depth, evidence-based coverage of 73 diseases and conditions includes key diagnostic criteria, pathophysiology of diseases, and therapeutic rationales. Coverage of potential interactions between drugs, herbs, and supplements ensures the safest possible use for each of 79 herbs and supplements. Diagnostic procedures include practical, easy-to-follow descriptions of evidence-based techniques plus discussions of clinical application of diet analysis, food allergy testing, immune function assessment, fatty acid profiling, hair mineral analysis, and other diagnostic approaches. Common therapeutic modalities are described and reviewed, including botanical medicine, nutritional therapy, therapeutic fasting, exercise therapy, hydrotherapy, counseling, acupuncture, homeopathy, and soft tissue manipulation. Coverage of syndromes and therapies helps in understanding the underlying causes of diseases by discussing topics such as food reactions, functional toxicology, sports nutrition, stress management, and breathing pattern disorders. Coverage of the philosophy of natural medicine includes its history and background, with discussions of toxicity, detoxification, and scientific documentation of the healing actions of nature and natural substances. Internationally known authors Joseph Pizzorno and Michael Murray and more than 90 expert contributors provide material that is up to date, accurate, and informed. More than 10,000 research literature citations show that the content is based on science rather than opinions or anecdotes. 13 useful appendices offer quick lookup of frequently used charts, handouts, and information.

Cumulated Index Medicus

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ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

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ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biomedical Index to PHS-supported Research: pt. A. Subject access A-H by :

Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Underlying Mechanisms and Novel Approaches for Diabetes and its Related Complications

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Publisher : Frontiers Media SA
ISBN 13 : 2832553753
Total Pages : 392 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Underlying Mechanisms and Novel Approaches for Diabetes and its Related Complications by : Qi Pan

Download or read book The Underlying Mechanisms and Novel Approaches for Diabetes and its Related Complications written by Qi Pan and published by Frontiers Media SA. This book was released on 2024-08-30 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which severely affects the quality of life and survival of patients. The latest data from the International Diabetes Federation showed that there are approximately 537 million diabetic patients globally in 2021, and it is expected to reach 783 million by 2045. The treatment regime of diabetic patients mainly refers to the management of blood glucose and its complications. At present, typical hypoglycemic medications include insulin and non-insulin hypoglycemic drugs, which can be subdivided into a-glucosidase inhibitors, metformin, thiazolidinediones, sulfonylureas, glinides, DPP-4i, GLP-1RA, and SGLT-2i. Diabetic patients with poor islet function usually require insulin replacement, but the majority of patients fail to meet ideal therapeutic targets with multiple hypoglycemic drug combinations (including insulin). Furthermore, poor glycemic control is closely associated with an increased risk of diabetes complications, consequently an increased rate of mortality. More recently, promising new drugs and therapies emerged, which have many other important benefits beyond glucose-lowering. In addition, some traditional Chinese medicine have gradually revealed their therapeutic advantages. All of them provide more choices for the treatment of diabetes patients.