Cardiac Electrophysiology Methods and Models

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441966587
Total Pages : 490 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cardiac Electrophysiology Methods and Models by : Daniel C. Sigg

Download or read book Cardiac Electrophysiology Methods and Models written by Daniel C. Sigg and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Mathematical and Numerical Modeling of the Cardiovascular System and Applications

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Publisher : Springer
ISBN 13 : 3319966499
Total Pages : 252 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Mathematical and Numerical Modeling of the Cardiovascular System and Applications by : Daniele Boffi

Download or read book Mathematical and Numerical Modeling of the Cardiovascular System and Applications written by Daniele Boffi and published by Springer. This book was released on 2018-11-03 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.

Cardiac Arrhythmias

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Publisher : Springer Science & Business Media
ISBN 13 : 1447153162
Total Pages : 678 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Cardiac Arrhythmias by : Ambrose S. Kibos

Download or read book Cardiac Arrhythmias written by Ambrose S. Kibos and published by Springer Science & Business Media. This book was released on 2013-12-13 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.​

Cardiac Mechano-electric Feedback and Arrhythmias

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Author :
Publisher : Saunders
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cardiac Mechano-electric Feedback and Arrhythmias by : Peter Kohl

Download or read book Cardiac Mechano-electric Feedback and Arrhythmias written by Peter Kohl and published by Saunders. This book was released on 2005 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kohl (Cardio Mechano-Electric Feedback Lab, Oxford University) documents the role of mechano-electric feedback (MEF) in electrical and mechanical pathological remodeling of cardiac function. Sections cover sub-cellular mechanisms of cardiac MEF, effects of MEF on cardiac cellular electrophysiology, experimental manifestations of MEF in the heart, cardiac MEF in normal physiology, cardiac MEF as a pathogenic mechanism, MEF as a mechanism involved in therapeutic interventions, and the outlook for the future. B&w and color photos and medical images are included. Annotation: 2005 Book News, Inc., Portland, OR (booknews.com).

Mathematical Cardiac Electrophysiology

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Author :
Publisher : Springer
ISBN 13 : 3319048015
Total Pages : 410 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mathematical Cardiac Electrophysiology by : Piero Colli Franzone

Download or read book Mathematical Cardiac Electrophysiology written by Piero Colli Franzone and published by Springer. This book was released on 2014-10-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Cardiovascular Mathematics

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Publisher : Springer Science & Business Media
ISBN 13 : 8847011523
Total Pages : 528 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Cardiovascular Mathematics by : Luca Formaggia

Download or read book Cardiovascular Mathematics written by Luca Formaggia and published by Springer Science & Business Media. This book was released on 2010-06-27 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Molecular Genetics of Cardiac Electrophysiology

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792378297
Total Pages : 396 pages
Book Rating : 4.3/5 (782 download)

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Book Synopsis Molecular Genetics of Cardiac Electrophysiology by : C. Berul

Download or read book Molecular Genetics of Cardiac Electrophysiology written by C. Berul and published by Springer Science & Business Media. This book was released on 2000-04-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular basis for atrial fibrillation continues to be largely unknown, and therapy remains unchanged, aimed at controlling the heart rate and preventing systemic emboli with anticoagulation. Familial atrial fibrillation is more common than previously suspected. While atrial fibrillation is commonly associated with acquired heart disease, a significant proportion of individuals have early onset without other forms of heart disease, referred to as "lone" atrial fibrillators. It is also well recognized that atrial fibrillation occurs on a reversible or functional basis, without associated structural heart disease, such as with hyperthyroidism or of atrial fibrillation following surgery. It remains to be determined what percentage in these individuals is familial or due to a genetic predisposition. Mapping the locus for familial atrial fibrillation is the first step towards the identification of the gene. Isolation of the gene and subsequent identification of the responsible molecular genetic defect should provide a point of entry into the mechanism responsible for the familial form and the common acquired forms of the disease and eventually provide more effective therapy. We know that the ionic currents responsible for the action potential of the atrium is due to multiple channel proteins as is electrical conduction throughout the atria. Analogous to the ongoing genetic studies in patients with familial long QT syndrome, it is highly likely that defects in each of these channel proteins will be manifested in familial atrial fibrillation.

Multimodal Cardiovascular Imaging: Principles and Clinical Applications

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071613463
Total Pages : 462 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Multimodal Cardiovascular Imaging: Principles and Clinical Applications by : Olle Pahlm

Download or read book Multimodal Cardiovascular Imaging: Principles and Clinical Applications written by Olle Pahlm and published by McGraw Hill Professional. This book was released on 2011-03-24 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to using multimodal imaging in cardiac practice Interactive DVD includes moving images from the text 4 STAR DOODY'S REVIEW! "In addition to compiling the various imaging modalities used for clinical diagnosis in cardiovascular disease, the book also summarizes the present and future applications of combined imaging modalities for better understanding the underlying pathophysiologic basis of cardiovascular diseases....This book is unique in the way it comprehensively reviews both the current and future applications of multiple imaging modalities."--Doody's Review Service Multimodal Cardiovascular Imaging: Principles and Clinical Applications offers a unique “matrix” approach to help you choose the most appropriate combination of imaging modalities for the management of patients with cardiovascular disease. The book discusses the various options available, how they work, the benefits and drawbacks of each, and what modalities will best work in conjunction with each other for a specific condition. Featuring contributions from more than 60 international authors and enriched by 225 half-tone modality images and 130 full-color illustrations, Multimodal Cardiovascular Imaging: Principles and Clinical Applications is divided into three sections: Section 1 contains chapters that focus on the use of ten specific clinically available diagnostic modalities and their broad application to clinical cardiology. Modalities discussed include: Echocardiography Phonocardiography Myocardial Perfusion SPECT and PET Coronary Angiography Cardiac CT Section 2 includes six chapters that present “visions of the future” for combining multiple diagnostic modalities. They form the foundation for understanding the pathophysiologic basis of clinical cardiovascular conditions using prototypes, simulations, models, and tutorials. Section 3 considers several cardiovascular conditions and how multimodal imaging can provide diagnostic and therapeutic decision support to optimize the clinical care for each of them. Some chapters in this section also include case reports of how clinicians/scientists are using multimodal imaging modalities to improve their clinical therapeutic decision support. Conditions include: Congenital Heart Disease Ischemic Heart Disease Acute Myocardial Infarction Aortic Disease Atrial Fibrillation

Modeling and Simulating Cardiac Electrical Activity

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Publisher :
ISBN 13 : 9780750320641
Total Pages : 0 pages
Book Rating : 4.3/5 (26 download)

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Book Synopsis Modeling and Simulating Cardiac Electrical Activity by : David J. Christini

Download or read book Modeling and Simulating Cardiac Electrical Activity written by David J. Christini and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.

IPSCs - State of the Science

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Author :
Publisher : Elsevier
ISBN 13 : 0323857671
Total Pages : 316 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis IPSCs - State of the Science by : Alexander Birbrair

Download or read book IPSCs - State of the Science written by Alexander Birbrair and published by Elsevier. This book was released on 2022-01-19 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more Contributed by world-renowned experts in the field

Cardiovascular Computing—Methodologies and Clinical Applications

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Publisher : Springer
ISBN 13 : 9811050929
Total Pages : 354 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Cardiovascular Computing—Methodologies and Clinical Applications by : Spyretta Golemati

Download or read book Cardiovascular Computing—Methodologies and Clinical Applications written by Spyretta Golemati and published by Springer. This book was released on 2019-02-12 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive guide to the state-of-the-art in cardiovascular computing and highlights novel directions and challenges in this constantly evolving multidisciplinary field. The topics covered span a wide range of methods and clinical applications of cardiovascular computing, including advanced technologies for the acquisition and analysis of signals and images, cardiovascular informatics, and mathematical and computational modeling.

Handbook of Psychocardiology

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Publisher : Springer
ISBN 13 : 9789812872050
Total Pages : 0 pages
Book Rating : 4.8/5 (72 download)

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Book Synopsis Handbook of Psychocardiology by : Marlies Alvarenga

Download or read book Handbook of Psychocardiology written by Marlies Alvarenga and published by Springer. This book was released on 2017-11-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook brings together the full weight of contemporary evidence bearing on what is now commonly termed “psycho-cardiology”. It focuses on the role of psycho-social factors in the genesis and clinical management of cardiovascular disease (CVD). The book constitutes a critically reviewed compendium of current knowledge in the area, coupled with guides to evidence-based best practice in the field of psycho-cardiology. The following categories are covered: Social/demographic risk for CVD, Personality and CVD risk, Stress and CVD risk, Psychopathology (particularly affective disorders) and CVD risk, The psychological management of those with clinical CVD, Psychology in the prevention of CVD. The book integrates the evidence into a compelling argument that clinicians, researchers and those in public health will discount the role of psychological factors in regard to CVD at their own peril. And importantly for clinicians charged with the care of patients with CVD, the book poses the argument that failure to recognize the links between psychological factors and CVD may well be at the considerable peril of those patients under their care.

Modified Mass-spring System for Physically Based Deformation Modeling

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Publisher : KIT Scientific Publishing
ISBN 13 : 3866447426
Total Pages : 244 pages
Book Rating : 4.8/5 (664 download)

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Book Synopsis Modified Mass-spring System for Physically Based Deformation Modeling by : Oussama Jarrousse

Download or read book Modified Mass-spring System for Physically Based Deformation Modeling written by Oussama Jarrousse and published by KIT Scientific Publishing. This book was released on 2014-09 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass-spring systems are considered the simplest and most intuitive of all deformable models. They are computationally efficient, and can handle large deformations with ease. But they suffer several intrinsic limitations. In this book a modified mass-spring system for physically based deformation modeling that addresses the limitations and solves them elegantly is presented. Several implementations in modeling breast mechanics, heart mechanics and for elastic images registration are presented.

Analysis and Assessment of Cardiovascular Function

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387982823
Total Pages : 414 pages
Book Rating : 4.9/5 (828 download)

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Book Synopsis Analysis and Assessment of Cardiovascular Function by : Gary M. Drzewiecki

Download or read book Analysis and Assessment of Cardiovascular Function written by Gary M. Drzewiecki and published by Springer Science & Business Media. This book was released on 1998 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of cardiovascular function is vital to contemporary biomedical research. However, integration between cellular and subcellular research and organ-level studies is often lacking, as is integration of clinical and basic investigation. This book examines cardiovascular system function from the perspectives of assessment and analysis, with a focus on evaluating function at different anatomical levels using a combination of analytical, experimental, and clinical measurements.

Computing the Electrical Activity in the Heart

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Publisher : Springer Science & Business Media
ISBN 13 : 3540334378
Total Pages : 323 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Computing the Electrical Activity in the Heart by : Joakim Sundnes

Download or read book Computing the Electrical Activity in the Heart written by Joakim Sundnes and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.

Implantable Defibrillator Therapy: A Clinical Guide

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402071430
Total Pages : 428 pages
Book Rating : 4.0/5 (714 download)

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Book Synopsis Implantable Defibrillator Therapy: A Clinical Guide by : Antonio Pacifico

Download or read book Implantable Defibrillator Therapy: A Clinical Guide written by Antonio Pacifico and published by Springer Science & Business Media. This book was released on 2002-08-31 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable defibrillators as originally conceived by Michel Mirowski were limited to the detection and automatic termination of ventricular fibrillation. In the original "AID" device, the detection algoritlun sought to distinguish sinus rhytlun from ventricular fibrillation by identifying the "more sinusoidal waveform of ventricular fibrillation. " The therapeutic intervention was elicited only once deadly polymorphic rhythms had developed. It was rapidly learned, however, that ventricular fibrillation is usually preceded by ventricular tachycardia. Mirowski recognized the pivotal importance of developing algoritllms based on heart rate. Ventricular tachycardia detection allowed the successful development of interventions for the termination of ventricular tachyarrhythmias before they degenerated into ventricular fibrillation. Current device therapy no longer confines itself to tlle termination of chaotic rhythms but seeks to prevent them. Diagnostic algorithms moved upward along the chain of events leading to catastrophic rhytlulls. Rate smoothing algorithms were developed to prevent postextrasystolic pauses from triggering ventricular and atrial tachyarrhytlmlias. Beyond the renaissance of ectopy-centered strategies, long-term prevention received increasing attention. Multisite pacing therapies provided by "Arrhythmia Management Devices" were designed to reduce the "arrhytlunia burden" and optimize the synergy of cardiac contraction and relaxation. Clinical evidence now suggests that atrial fibrillation prevention by pacing is feasible and tllat biventricular pacing may be of benefit in selected patients with heart failure. However, these applications of device therapy that generally require ventricular defibrillation backup remain investigational and were not considered in this book.

DICOM Structured Reporting

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Author :
Publisher : PixelMed Publishing
ISBN 13 : 0970136900
Total Pages : 396 pages
Book Rating : 4.9/5 (71 download)

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Book Synopsis DICOM Structured Reporting by : David A. Clunie

Download or read book DICOM Structured Reporting written by David A. Clunie and published by PixelMed Publishing. This book was released on 2000 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: