A Brief Introduction to the Use of Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks

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Publisher : RTI Press
ISBN 13 :
Total Pages : 14 pages
Book Rating : 4./5 ( download)

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Book Synopsis A Brief Introduction to the Use of Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks by : F. Reed Johnson

Download or read book A Brief Introduction to the Use of Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks written by F. Reed Johnson and published by RTI Press. This book was released on 2009-08-31 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory decisions to approve, restrict development, or halt the marketing of new pharmaceuticals require evaluating the balance between benefits and risks, given the available evidence at a point in time. In response to concerns about how such decisions are reached, there is increasing interest in using patients' perceptions of the benefits of treatment features and their tolerance for possible risks to help inform regulatory decisions. Stated-choice methods, which measure stated preferences and are sometimes called discrete-choice experiments or conjoint analysis, are often the most valid and reliable techniques available for quantifying patient preferences because data on actual choices are limited. This introduction discusses how to adapt and apply stated-choice methods to quantitative benefit-risk analysis. We outline the conceptual framework for measuring patient preferences and the requirements for developing and administering a valid survey instrument. We also provide a numerical example illustrating how stated-choice data can be used to quantify benefit-risk tradeoff preferences. Finally, we discuss some limitations and practical considerations involving its use for regulatory and clinical decision making.

A Brief Introduction to Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks

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Publisher :
ISBN 13 :
Total Pages : 10 pages
Book Rating : 4.:/5 (856 download)

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Book Synopsis A Brief Introduction to Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks by : F. Reed Johnson

Download or read book A Brief Introduction to Stated-Choice Methods to Measure Preferences for Treatment Benefits and Risks written by F. Reed Johnson and published by . This book was released on 2009 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stated Choice Methods

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Publisher : Cambridge University Press
ISBN 13 : 1107717515
Total Pages : 436 pages
Book Rating : 4.1/5 (77 download)

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Book Synopsis Stated Choice Methods by : Jordan J. Louviere

Download or read book Stated Choice Methods written by Jordan J. Louviere and published by Cambridge University Press. This book was released on 2000-09-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding and predicting the behaviour of decision makers when choosing among discrete goods has been one of the most fruitful areas of applied research over the last thirty years. An understanding of individual consumer behaviour can lead to significant changes in product or service design, pricing strategy, distribution channel and communication strategy selection, as well as public welfare analysis. This graduate and practitioner guide, first published in 2000, deals with the study and prediction of consumer choice behaviour, concentrating on stated preference (SP) methods - placing decision makers in controlled experiments that yield hypothetical choices - rather than revealed preferences (RP) - actual choices in the market. It shows how SP methods can be implemented, from experimental design to econometric modelling, and suggests how to combine RP and SP data to get the best from each type. The book also presents an update of econometric approaches to choice modelling.

A Primer on Nonmarket Valuation

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Publisher : Springer
ISBN 13 : 9400771045
Total Pages : 508 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis A Primer on Nonmarket Valuation by : Patricia A. Champ

Download or read book A Primer on Nonmarket Valuation written by Patricia A. Champ and published by Springer. This book was released on 2017-02-08 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical book with clear descriptions of the most commonly used nonmarket methods. The first chapters of the book provide the context and theoretical foundation of nonmarket valuation along with a discussion of data collection procedures. The middle chapters describe the major stated- and revealed-preference valuation methods. For each method, the steps involved in implementation are laid out and carefully explained with supporting references from the published literature. The final chapters of the book examine the relevance of experimentation to economic valuation, the transfer of existing nonmarket values to new settings, and assessments of the reliability and validity of nonmarket values. The book is relevant to individuals in many professions at all career levels. Professionals in government agencies, attorneys involved with natural resource damage assessments, graduate students, and others will appreciate the thorough descriptions of how to design, implement, and analyze a nonmarket valuation study.

Researchers' Stated Preferences for Stated-Preference Methods

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Researchers' Stated Preferences for Stated-Preference Methods by : Semra Ozdemir

Download or read book Researchers' Stated Preferences for Stated-Preference Methods written by Semra Ozdemir and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: BACKGROUND: New and better methods are constantly being developed in applied research. Eventually, state-of-the-art procedures become state-of-the-practice procedures that are required for peer-reviewed publications. These methods have been extensively used and tested for validity in environmental economics and market research. Health economists are increasingly employing these methods to elicit patients' and physicians' preferences. However, the quality of data collected and the validity of results are sensitive to a number of researcher decisions. OBJECTIVES: The aim of this study is to quantify the degree of current consensus in the rapidly evolving area of stated-preference research in health valuation. METHODS: Stated-preference (SP) methods include both contingent-valuation and conjoint-analysis approaches. Conjoint analysis asks respondents to choose, rate or rank hypothetical or existing alternatives. Designing such a study requires numerous judgments involving such considerations as what features of the treatments to include, how many alternatives to show, how many groups of alternatives to show, how to construct alternatives to satisfy particular statistical criteria, and how to estimate preference parameters to obtain valid, unbiased results. The resulting tradeoff patterns reveal the underlying importance weights respondents use to evaluate alternatives. Employing the same method, we have developed a meta-survey of this same type to elicit researchers' preferences for the methods themselves. We surveyed researchers who have published manuscripts in peer-reviewed journals on stated preference methods in the last 10 years. We asked these researchers to evaluate hypothetical studies, where one of the stated preference methods, such as contingent valuation or stated choice approach was used. The researchers compared a series of pairs of hypothetical studies with specified characteristics in health applications. They were first asked which study is better and then asked which study they would recommend to use to inform policy decisions by an agency of the government where they reside. RESULTS: We used bivariate probit model to estimate researchers' preferences. Around 75% of the researchers in the sample were academic and about 40% reported that they reside in the US. Researchers were more likely to recommend a study to inform policy decisions if the survey is pre-tested or conducted by mail, there is a scope test, and the econometric model involves advanced modeling, such as random-parameters model. Researchers who have used contingent valuation studies were likely to recommend a study used contingent valuation and researchers who have used conjoint analysis studies were likely to recommend a study used conjoint analysis. While younger researchers were likely to recommend surveys conducted through mail, older researchers were likely not to recommend either study. The location of the researcher did not have any significant effect on researchers' preferences. CONCLUSION: Using an SP method to evaluate SP methods was a convenient and valid way of investigating current research. Our study results state that it is hard to reach a consensus among the researchers and there is room for improvement in health applications.

Best-Worst Scaling

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Publisher : Cambridge University Press
ISBN 13 : 1107043158
Total Pages : 363 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Best-Worst Scaling by : Jordan J. Louviere

Download or read book Best-Worst Scaling written by Jordan J. Louviere and published by Cambridge University Press. This book was released on 2015-09-23 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: First systematic treatment of best-worst scaling, explaining how to implement, analyze, and apply the theory across a range of disciplines.

The Construction of Optimal Stated Choice Experiments

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Publisher : John Wiley & Sons
ISBN 13 : 0470148551
Total Pages : 344 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Construction of Optimal Stated Choice Experiments by : Deborah J. Street

Download or read book The Construction of Optimal Stated Choice Experiments written by Deborah J. Street and published by John Wiley & Sons. This book was released on 2007-07-20 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and applied discussion of stated choice experiment constructions available The Construction of Optimal Stated Choice Experiments provides an accessible introduction to the construction methods needed to create the best possible designs for use in modeling decision-making. Many aspects of the design of a generic stated choice experiment are independent of its area of application, and until now there has been no single book describing these constructions. This book begins with a brief description of the various areas where stated choice experiments are applicable, including marketing and health economics, transportation, environmental resource economics, and public welfare analysis. The authors focus on recent research results on the construction of optimal and near-optimal choice experiments and conclude with guidelines and insight on how to properly implement these results. Features of the book include: Construction of generic stated choice experiments for the estimation of main effects only, as well as experiments for the estimation of main effects plus two-factor interactions Constructions for choice sets of any size and for attributes with any number of levels A discussion of designs that contain a none option or a common base option Practical techniques for the implementation of the constructions Class-tested material that presents theoretical discussion of optimal design Complete and extensive references to the mathematical and statistical literature for the constructions Exercise sets in most chapters, which reinforce the understanding of the presented material The Construction of Optimal Stated Choice Experiments serves as an invaluable reference guide for applied statisticians and practitioners in the areas of marketing, health economics, transport, and environmental evaluation. It is also ideal as a supplemental text for courses in the design of experiments, decision support systems, and choice models. A companion web site is available for readers to access web-based software that can be used to implement the constructions described in the book.

Discrete Choice Methods with Simulation

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Publisher : Cambridge University Press
ISBN 13 : 0521766559
Total Pages : 399 pages
Book Rating : 4.5/5 (217 download)

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Book Synopsis Discrete Choice Methods with Simulation by : Kenneth Train

Download or read book Discrete Choice Methods with Simulation written by Kenneth Train and published by Cambridge University Press. This book was released on 2009-07-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the new generation of discrete choice methods, focusing on the many advances that are made possible by simulation. Researchers use these statistical methods to examine the choices that consumers, households, firms, and other agents make. Each of the major models is covered: logit, generalized extreme value, or GEV (including nested and cross-nested logits), probit, and mixed logit, plus a variety of specifications that build on these basics. Simulation-assisted estimation procedures are investigated and compared, including maximum stimulated likelihood, method of simulated moments, and method of simulated scores. Procedures for drawing from densities are described, including variance reduction techniques such as anithetics and Halton draws. Recent advances in Bayesian procedures are explored, including the use of the Metropolis-Hastings algorithm and its variant Gibbs sampling. The second edition adds chapters on endogeneity and expectation-maximization (EM) algorithms. No other book incorporates all these fields, which have arisen in the past 25 years. The procedures are applicable in many fields, including energy, transportation, environmental studies, health, labor, and marketing.

Using Surveys to Value Public Goods

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Publisher : Resources for the Future
ISBN 13 : 9780915707324
Total Pages : 496 pages
Book Rating : 4.7/5 (73 download)

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Book Synopsis Using Surveys to Value Public Goods by : Robert Cameron Mitchell

Download or read book Using Surveys to Value Public Goods written by Robert Cameron Mitchell and published by Resources for the Future. This book was released on 1989 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides decision makers, policy analysts, and social scientists, with a detailed discussion of a new techniques for the valuation of goods not traded in prevate markets.

Cochrane Handbook for Systematic Reviews of Interventions

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Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Patient Involvement in Health Technology Assessment

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Publisher : Springer
ISBN 13 : 9811040680
Total Pages : 431 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Patient Involvement in Health Technology Assessment by : Karen M. Facey

Download or read book Patient Involvement in Health Technology Assessment written by Karen M. Facey and published by Springer. This book was released on 2017-05-15 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to offer a comprehensive guide to involving patients in health technology assessment (HTA). Defining patient involvement as patient participation in the HTA process and research into patient aspects, this book includes detailed explanations of approaches to participation and research, as well as case studies. Patient Involvement in HTA enables researchers, postgraduate students, HTA professionals and experts in the HTA community to study these complementary ways of taking account of patients’ knowledge, experiences, needs and preferences. Part I includes chapters discussing the ethical rationale, terminology, patient-based evidence, participation and patient input. Part II sets out methodology including: Qualitative Evidence Synthesis, Discrete Choice Experiments, Analytical Hierarchy Processes, Ethnographic Fieldwork, Deliberative Methods, Social Media Analysis, Patient-Reported Outcome Measures, patients as collaborative research partners and evaluation. Part III contains 15 case studies setting out current activities by HTA bodies on five continents, health technology developers and patient organisations. Each part includes discussion chapters from leading experts in patient involvement. A final chapter reflects on the need to clearly define the goals for patient involvement within the context of the HTA to identify the optimal approach. With cohesive contributions from more than 80 authors from a variety of disciplines around the globe, it is hoped this book will serve as a catalyst for collaboration to further develop patient involvement to improve HTA. "If you’re not involving patients, you're not doing HTA!" - Dr. Brian O’Rourke, President and CEO of CADTH, Chair of INAHTA

Small Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Economic Valuation with Stated Preference Techniques

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Publisher : Edward Elgar Publishing
ISBN 13 :
Total Pages : 490 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Economic Valuation with Stated Preference Techniques by : Ian Bateman

Download or read book Economic Valuation with Stated Preference Techniques written by Ian Bateman and published by Edward Elgar Publishing. This book was released on 2002 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual offers a detailed, up-to-date explanation of how to carry out stated preference techniques. The techniques use surveys to ask individuals how much they would be willing to pay or willing to accept in compensation for gains or losses of non-market goods and services. Applications of the technique include changes in air and water quality; noise nuisance; health care; risk; recorded heritage; cultural assets; habitats; Landscape and so on. It shows how to choose the most appropriate technique and how to design the questionnaires. Detailed advice on econometric analysis is provided, as well as explanation of the pitfalls that need to be avoided.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

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Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Designing and Conducting Health Surveys

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Publisher : John Wiley & Sons
ISBN 13 : 1118046676
Total Pages : 474 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Designing and Conducting Health Surveys by : Lu Ann Aday

Download or read book Designing and Conducting Health Surveys written by Lu Ann Aday and published by John Wiley & Sons. This book was released on 2011-01-20 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing and Conducting Health Surveys is written for students, teachers, researchers, and anyone who conducts health surveys. This third edition of the standard reference in the field draws heavily on the most recent methodological research on survey design and the rich storehouse of insights and implications provided by cognitive research on question and questionnaire design in particular. This important resource presents a total survey error framework that is a useful compass for charting the dangerous waters between systematic and random errors that inevitably accompany the survey design enterprise. In addition, three new studies based on national, international, and state and local surveys—the UNICEF Multiple Indicator Cluster Surveys, California Health Interview Survey, and National Dental Malpractice Survey—are detailed that illustrate the range of design alternatives available at each stage of developing a survey and provide a sound basis for choosing among them.

The Prevention and Treatment of Missing Data in Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 030918651X
Total Pages : 163 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Qualitative Research in Health Care

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Publisher : John Wiley & Sons
ISBN 13 : 1119410835
Total Pages : 278 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Qualitative Research in Health Care by : Catherine Pope

Download or read book Qualitative Research in Health Care written by Catherine Pope and published by John Wiley & Sons. This book was released on 2020-02-03 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the essential information that health care researchers and health professionals need to understand the basics of qualitative research Now in its fourth edition, this concise, accessible, and authoritative introduction to conducting and interpreting qualitative research in the health care field has been fully revised and updated. Continuing to introduce the core qualitative methods for data collection and analysis, this new edition also features chapters covering newer methods which are becoming more widely used in the health research field; examining the role of theory, the analysis of virtual and digital data, and advances in participatory approaches to research. Qualitative Research in Health Care, 4th Edition looks at the interface between qualitative and quantitative research in primary mixed method studies, case study research, and secondary analysis and evidence synthesis. The book further offers chapters covering: different research designs, ethical issues in qualitative research; interview, focus group and observational methods; and documentary and conversation analysis. A succinct, and practical guide quickly conveying the essentials of qualitative research Updated with chapters on new and increasingly used methods of data collection including digital and web research Features new examples and up-to-date references and further reading The fourth edition of Qualitative Research in Health Care is relevant to health care professionals, researchers and students in health and related disciplines.