X-ray Crystallographic Studies of Cellular Retinoic Acid-binding Protein II Mutants Designed as Rhodopsin Mimics

Download X-ray Crystallographic Studies of Cellular Retinoic Acid-binding Protein II Mutants Designed as Rhodopsin Mimics PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (129 download)

DOWNLOAD NOW!


Book Synopsis X-ray Crystallographic Studies of Cellular Retinoic Acid-binding Protein II Mutants Designed as Rhodopsin Mimics by : Xiaofei Jia

Download or read book X-ray Crystallographic Studies of Cellular Retinoic Acid-binding Protein II Mutants Designed as Rhodopsin Mimics written by Xiaofei Jia and published by . This book was released on 2008 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

X-ray Crystallographic Studies of Mutants of Cellular Retinoic Acid Binding Protein (II) Toward Designing a Mimic of Rhodopsin

Download X-ray Crystallographic Studies of Mutants of Cellular Retinoic Acid Binding Protein (II) Toward Designing a Mimic of Rhodopsin PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.3/5 (129 download)

DOWNLOAD NOW!


Book Synopsis X-ray Crystallographic Studies of Mutants of Cellular Retinoic Acid Binding Protein (II) Toward Designing a Mimic of Rhodopsin by : Soheila Vaezeslami

Download or read book X-ray Crystallographic Studies of Mutants of Cellular Retinoic Acid Binding Protein (II) Toward Designing a Mimic of Rhodopsin written by Soheila Vaezeslami and published by . This book was released on 2006 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dissertation Abstracts International

Download Dissertation Abstracts International PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!


Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:

X-ray Crystallographic Studies Of Designed Peptides, Self Assembling Pseudopeptides And Molecular Modeling

Download X-ray Crystallographic Studies Of Designed Peptides, Self Assembling Pseudopeptides And Molecular Modeling PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (656 download)

DOWNLOAD NOW!


Book Synopsis X-ray Crystallographic Studies Of Designed Peptides, Self Assembling Pseudopeptides And Molecular Modeling by :

Download or read book X-ray Crystallographic Studies Of Designed Peptides, Self Assembling Pseudopeptides And Molecular Modeling written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural studies of peptides has relevance for various applications, like, in de novo design of proteins, in designing better catalysts for organic synthesis, in structure based drug design, in the design and construction of synthetic protein mimics and in building novel materials via supramolecular self assembly. Crystal structure determination of peptides is expected to provide information about their static structure, mode of aggregation, solvation and hydrogen bond interactions of the sequences in the solid state. Comparison and analysis of the related structures from the database analysis could provide information about sequence dependent conformational features, which eventually would act as precursor for de novo protein design. Self assembling processes are common throughout nature and technology. Living cells self assemble, and understanding life will therefore require an understanding of self assembly. Supramolecular chemistry has become an area of intense research, partly inspired by biological ensembles in nature, such as collagen and enzymes or protein assemblies in general. Understanding, inducing, and directing such self assembling processes are key to unraveling the progressive emergence of complex matter. Most of the drugs available today have a broad spectrum of action in that they can act on more than one receptor and the mechanism of action of these drugs are poorly understood. Homology modeling of receptors and docking studies with drug molecules (both peptides and non-peptides) would result in a better understanding of the mechanism of drug-receptor binding thus resulting in the design of more specific and effective drugs. This thesis reports the results of X-ray crystallographic studies of ten molecules listed below (Ter: terephthalic acid) and the molecular model of cholecystokinin type 1 receptor (CCK1R). The abbreviations used for the sequences are given in parenthesis. Boc-Gly-Dpg-Gly-Leu-OMe (GDGL), C24H44N4O7 Boc-Val-Ala-Leu-Dpg-Val-Ala.

X-ray Crystallographic Studies of Three Nucleic Acid Binding Proteins

Download X-ray Crystallographic Studies of Three Nucleic Acid Binding Proteins PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis X-ray Crystallographic Studies of Three Nucleic Acid Binding Proteins by : Bart L. Staker

Download or read book X-ray Crystallographic Studies of Three Nucleic Acid Binding Proteins written by Bart L. Staker and published by . This book was released on 2000 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

Download Cumulated Index Medicus PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 1874 pages
Book Rating : 4.:/5 (31 download)

DOWNLOAD NOW!


Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1998 with total page 1874 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Dimerization and Oligomerization in Biology

Download Protein Dimerization and Oligomerization in Biology PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461432294
Total Pages : 184 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!


Book Synopsis Protein Dimerization and Oligomerization in Biology by : Jacqueline M. Matthews

Download or read book Protein Dimerization and Oligomerization in Biology written by Jacqueline M. Matthews and published by Springer Science & Business Media. This book was released on 2012-09-04 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Cambridge Scientific Biochemistry Abstracts

Download Cambridge Scientific Biochemistry Abstracts PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 1498 pages
Book Rating : 4.E/5 ( download)

DOWNLOAD NOW!


Book Synopsis Cambridge Scientific Biochemistry Abstracts by :

Download or read book Cambridge Scientific Biochemistry Abstracts written by and published by . This book was released on 1993-07 with total page 1498 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of The Cell

Download Molecular Biology of The Cell PDF Online Free

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

DOWNLOAD NOW!


Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tolerable upper intake levels for vitamins and minerals

Download Tolerable upper intake levels for vitamins and minerals PDF Online Free

Author :
Publisher :
ISBN 13 : 9789291990146
Total Pages : 478 pages
Book Rating : 4.9/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Tolerable upper intake levels for vitamins and minerals by : European Commission. Scientific Committee on Food

Download or read book Tolerable upper intake levels for vitamins and minerals written by European Commission. Scientific Committee on Food and published by . This book was released on 2006 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Design of Ligand Binding Proteins

Download Computational Design of Ligand Binding Proteins PDF Online Free

Author :
Publisher : Humana
ISBN 13 : 9781493935673
Total Pages : 0 pages
Book Rating : 4.9/5 (356 download)

DOWNLOAD NOW!


Book Synopsis Computational Design of Ligand Binding Proteins by : Barry L. Stoddard

Download or read book Computational Design of Ligand Binding Proteins written by Barry L. Stoddard and published by Humana. This book was released on 2016-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Biological & Agricultural Index

Download Biological & Agricultural Index PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 2984 pages
Book Rating : 4.0/5 ( download)

DOWNLOAD NOW!


Book Synopsis Biological & Agricultural Index by :

Download or read book Biological & Agricultural Index written by and published by . This book was released on 1997 with total page 2984 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Make Life Visible

Download Make Life Visible PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 9811379084
Total Pages : 292 pages
Book Rating : 4.8/5 (113 download)

DOWNLOAD NOW!


Book Synopsis Make Life Visible by : Yoshiaki Toyama

Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

Molecular Pharmacology

Download Molecular Pharmacology PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118451953
Total Pages : 675 pages
Book Rating : 4.1/5 (184 download)

DOWNLOAD NOW!


Book Synopsis Molecular Pharmacology by : John Dickenson

Download or read book Molecular Pharmacology written by John Dickenson and published by John Wiley & Sons. This book was released on 2012-11-30 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.

Pediatric Retina

Download Pediatric Retina PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642120415
Total Pages : 459 pages
Book Rating : 4.6/5 (421 download)

DOWNLOAD NOW!


Book Synopsis Pediatric Retina by : James D. Reynolds

Download or read book Pediatric Retina written by James D. Reynolds and published by Springer Science & Business Media. This book was released on 2010-09-14 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric retinal diseases are not simply retinal diseases that occur in children; rather, they are unique disorders that often are not found in adults. This textbook of the pediatric retina offers in-depth guidance on congenital and acquired diseases of the retina in the pediatric population. It is organized according to disease onset and timing, as well as anatomy. All chapters are written by leading authorities in the field from both the pediatric and the retinal perspective. A multidisciplinary approach to the topic is adopted, and critical information is included on disease classification and diagnosis, pathophysiology, genetics, complications, and prognosis. Pediatric Retina will be a useful source of information for pediatric ophthalmologists, retina specialists, and other eye care providers who care for children.

Carotenoids

Download Carotenoids PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1420052314
Total Pages : 562 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Carotenoids by : John T. Landrum

Download or read book Carotenoids written by John T. Landrum and published by CRC Press. This book was released on 2009-12-21 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties presents a b

Color Atlas of Biochemistry

Download Color Atlas of Biochemistry PDF Online Free

Author :
Publisher : Thieme
ISBN 13 : 1604061235
Total Pages : 482 pages
Book Rating : 4.6/5 (4 download)

DOWNLOAD NOW!


Book Synopsis Color Atlas of Biochemistry by : Jan Koolman

Download or read book Color Atlas of Biochemistry written by Jan Koolman and published by Thieme. This book was released on 2011-01-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Totally revised and expanded, the Color Atlas of Biochemistry presents the fundamentals of human and mammalian biochemistry on 215 stunning color plates.Alongside a short introduction to chemistry and the classical topics of biochemistry, the 2nd edition covers new approaches and aspects in biochemistry, such as links between chemical structure and biological function or pathways for information transfer, as well as recent developments and discoveries, such as the structures of many new important molecules. Key features of this title include:- The unique combination of highly effective color graphics and comprehensive figure legends;- Unified color-coding of atoms, coenzymes, chemical classes, and cell organelles that allows quick recognition of all involved systems;- Computer graphics provide simulated 3D representation of many important molecules.This Flexibook is ideal for students of medicine and biochemistry and a valuable source of reference for practitioners.