What To Do When Antibiotics Dont Work

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Superbug

Author : Maryn McKenna
Publisher : Simon and Schuster
ISBN 13 : 9781439171837
Total Pages : 288 pages
Book Rating : 4.1/5 (718 download)

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Book Synopsis Superbug by : Maryn McKenna

Download or read book Superbug written by Maryn McKenna and published by Simon and Schuster. This book was released on 2010-03-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."

The Drugs Don't Work

Author : Professor Dame Sally Davies
Publisher : Penguin UK
ISBN 13 : 0241968887
Total Pages : 50 pages
Book Rating : 4.2/5 (419 download)

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Book Synopsis The Drugs Don't Work by : Professor Dame Sally Davies

Download or read book The Drugs Don't Work written by Professor Dame Sally Davies and published by Penguin UK. This book was released on 2013-09-15 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.

Antimicrobial Resistance

Author : Institute of Medicine
Publisher :
ISBN 13 : 9780309312868
Total Pages : 0 pages
Book Rating : 4.3/5 (128 download)

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Book Synopsis Antimicrobial Resistance by : Institute of Medicine

Download or read book Antimicrobial Resistance written by Institute of Medicine and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine launched an innovative outreach program in 1988. Through the generosity of the Rosenthal Family Foundation (formerly the Richard and Hinda Rosenthal Foundation), a discussion series was created to bring greater attention to some of the significant health policy issues facing our nation today. Each year a major health topic is addressed through remarks and conversation between experts in the field. The IOM later publishes the proceedings from this event for the benefit of a wider audience. This volume summarizes remarks by and an engaging discussion with Dr. Rima Khabbaz, Dr. Stuart Levy, Dr. Margaret (Peg) Riley, and Dr. Brad Spellberg on "Antimicrobial Resistance: A Problem Without Borders." The Centers for Disease Control and Prevention identified antimicrobial resistance as one of five urgent health threats facing the United States this year. Antimicrobial resistance is a global health security threat that will demand collaboration from many stakeholders around the world. This report highlights the crosscutting character of antimicrobial resistance and the needs for many disciplines to be brought together to be able to deal with it more effectively.

When Antibiotics Fail

Author : The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada
Publisher : Council of Canadian Academies
ISBN 13 : 1926522753
Total Pages : 268 pages
Book Rating : 4.9/5 (265 download)

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Book Synopsis When Antibiotics Fail by : The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada

Download or read book When Antibiotics Fail written by The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada and published by Council of Canadian Academies. This book was released on 2019-11-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics Fail examines the current impacts of AMR on our healthcare system, projects the future impact on Canada’s GDP, and looks at how widespread resistance will influence the day-to-day lives of Canadians. The report examines these issues through a One Health lens, recognizing the interconnected nature of AMR, from healthcare settings to the environment to the agriculture sector. It is the most comprehensive report to date on the economic impact of AMR in Canada.

Biography of Resistance

Author : Muhammad H. Zaman
Publisher : HarperCollins
ISBN 13 : 0062862987
Total Pages : 300 pages
Book Rating : 4.0/5 (628 download)

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Book Synopsis Biography of Resistance by : Muhammad H. Zaman

Download or read book Biography of Resistance written by Muhammad H. Zaman and published by HarperCollins. This book was released on 2020-04-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

Antibiotics and Antibiotic Resistance

Author : Ola Sköld
Publisher : John Wiley & Sons
ISBN 13 : 1118075587
Total Pages : 181 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Antibiotics and Antibiotic Resistance by : Ola Sköld

Download or read book Antibiotics and Antibiotic Resistance written by Ola Sköld and published by John Wiley & Sons. This book was released on 2011-10-07 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance poses for medicinal and drug-related fields, and perhaps trigger more research and discoveries to fight antibiotic resistant strains. Current overviews of the topic are included, along with specific discussions on the individual mechanisms (betalactams, glycopeptides, aminoglycosides, etc) used in various antibacterial agents and explanations of how resistances to those develop. Methods for counteracting resistance development in bacteria are discussed as well.

Big Chicken

Author : Maryn McKenna
Publisher : National Geographic Books
ISBN 13 : 1426217668
Total Pages : 404 pages
Book Rating : 4.4/5 (262 download)

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Book Synopsis Big Chicken by : Maryn McKenna

Download or read book Big Chicken written by Maryn McKenna and published by National Geographic Books. This book was released on 2017-09-12 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this eye-opening exposé, acclaimed health journalist and National Geographic contributor Maryn McKenna documents how antibiotics transformed chicken from local delicacy to industrial commodity—and human health threat—uncovering the ways we can make America's favorite meat safer again. What you eat matters—for your health, for the environment, and for future generations. In this riveting investigative narrative, McKenna dives deep into the world of modern agriculture by way of chicken: from the farm where it's raised directly to your dinner table. Consumed more than any other meat in the United States, chicken is emblematic of today's mass food-processing practices and their profound influence on our lives and health. Tracing its meteoric rise from scarce treat to ubiquitous global commodity, McKenna reveals the astounding role of antibiotics in industrial farming, documenting how and why "wonder drugs" revolutionized the way the world eats—and not necessarily for the better. Rich with scientific, historical, and cultural insights, this spellbinding cautionary tale shines a light on one of America's favorite foods—and shows us the way to safer, healthier eating for ourselves and our children. In August 2019 this book will be published in paperback with the title Plucked: Chicken, Antibiotics, and How Big Business Changed the Way the World Eats.

Review of Progress on Antimicrobial Resistance

Author : Charles Clift
Publisher :
ISBN 13 : 9781784133689
Total Pages : 16 pages
Book Rating : 4.1/5 (336 download)

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Book Synopsis Review of Progress on Antimicrobial Resistance by : Charles Clift

Download or read book Review of Progress on Antimicrobial Resistance written by Charles Clift and published by . This book was released on 2019 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309168309
Total Pages : 333 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Resistance Phenomenon in Microbes and Infectious Disease Vectors by : Institute of Medicine

Download or read book The Resistance Phenomenon in Microbes and Infectious Disease Vectors written by Institute of Medicine and published by National Academies Press. This book was released on 2003-03-26 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Antibiotics

Author : Mary E. Wilson
Publisher : What Everyone Needs to Know(r)
ISBN 13 : 0190663413
Total Pages : 433 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Antibiotics by : Mary E. Wilson

Download or read book Antibiotics written by Mary E. Wilson and published by What Everyone Needs to Know(r). This book was released on 2019 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know(R) examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know(R) offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.

What You Need to Know about Infectious Disease

Author : Madeline Drexler
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis What You Need to Know about Infectious Disease by : Madeline Drexler

Download or read book What You Need to Know about Infectious Disease written by Madeline Drexler and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antibiotic Resistance

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309156114
Total Pages : 496 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Antibiotic Resistance by : Institute of Medicine

Download or read book Antibiotic Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-10 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Natural Alternatives to Antibiotics

Author : John McKenna
Publisher : Penguin
ISBN 13 : 9780895298393
Total Pages : 206 pages
Book Rating : 4.2/5 (983 download)

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Book Synopsis Natural Alternatives to Antibiotics by : John McKenna

Download or read book Natural Alternatives to Antibiotics written by John McKenna and published by Penguin. This book was released on 1998 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. McKenna offers information on the herbal remedies, nutritional supplements, and dietary changes that can combat bacterial infections without the use of antibiotics.

Mayo Clinic on Digestive Health

Author : Sahil Khanna
Publisher : Rosetta Books
ISBN 13 : 0795352891
Total Pages : 446 pages
Book Rating : 4.7/5 (953 download)

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Book Synopsis Mayo Clinic on Digestive Health by : Sahil Khanna

Download or read book Mayo Clinic on Digestive Health written by Sahil Khanna and published by Rosetta Books. This book was released on 2020-01-22 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identify and treat digestive problems before they become difficult to manage—with this comprehensive reference from the world-renowned Mayo Clinic. Digestive problems are among the most common reasons people see doctors and take medication. This updated fourth edition of Mayo Clinic on Digestive Health is an authoritative yet practical reference manual that includes information on everything from healthy digestion to cancer treatment. The book is packed with helpful advice on treating common digestive conditions and preventing serious disease, with information on: Belching, bloating and gas • Celiac disease • Colorectal cancer • Constipation and diarrhea • Crohn’s disease and ulcerative colitis • Diverticular disease • Gallbladder disease • Heartburn and GERD • Irritable bowel syndrome • Liver disease • Pancreatic disease • Swallowing difficulties • Ulcers and stomach pain Also covered are diagnostic testing, mealtime recommendations and self-care tips for relieving discomfort, and the latest information on endoscopic ultrasound, virtual colonoscopy, and the newer minimally invasive treatments for gastroesophageal reflux disease (GERD).

Antibiotics

Author : Christopher Walsh
Publisher : John Wiley & Sons
ISBN 13 : 1555819311
Total Pages : 477 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Antibiotics by : Christopher Walsh

Download or read book Antibiotics written by Christopher Walsh and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

Resistant

Author : Rachael Sparks
Publisher : SparkPress
ISBN 13 : 1943006741
Total Pages : 242 pages
Book Rating : 4.9/5 (43 download)

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Book Synopsis Resistant by : Rachael Sparks

Download or read book Resistant written by Rachael Sparks and published by SparkPress. This book was released on 2018-10-16 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thrilling debut in the style of Crichton or A.G. Riddle, Resistant imagines a chilling—and entirely plausible—future where antibiotics don't work, and weaves adventure, romance, and science into a thrilling chase for a cure. In the final battle with drug-resistant bacteria, one woman's blood holds a secret weapon. Rory and her father have survived the antibiotic crisis that has killed millions, including Rory’s mother—but ingenuity and perseverance aren’t their only advantages. When a stoic and scarred young military veteran enters their quiet life, Rory is drawn to him against her better judgment . . . until he exposes the secrets her mother and father kept from her, including the fact that her own blood may hold the cure the world needs, and she is the target of groups fighting to reach it first. When the government comes after Rory, aiming to use her for a cure it can sell to the highest bidder, she’s forced to flee with her father and their new protector. But can she find the new path of human evolution before the government finds her?

The Antibiotic Paradox

Author : Stuart B. Levy
Publisher : Springer
ISBN 13 : 1489960422
Total Pages : 284 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis The Antibiotic Paradox by : Stuart B. Levy

Download or read book The Antibiotic Paradox written by Stuart B. Levy and published by Springer. This book was released on 2013-11-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of antibiotics heralded medicine's triumph over previously fatal diseases that once destroyed entire civilizations - thus earning their reputation as miracle drugs. But today, the terrifying reality of antibiotic-resistant bacteria resulting from our widespread misuse of antibiotics forewarns us that the miracle may be coming to an end. The seemingly innocent consumer who demands antibiotics to treat nonbacterial diseases such as the common cold or plays doctor by saving old prescriptions for later use is paving the way for a future of antibiotic failure. "What harm can it do?" is a popular refrain of people worldwide as they pop another antibiotic pill. Dr. Stuart Levy - the leading international expert on hazards of antibiotic misuse - reveals how this cavalier and naive attitude about the power of antibiotics can have deadly consequences. He explains that we are presently witnessing a massive evolutionary change in bacteria. This build-up of new antibiotic-resistant bacteria in individuals and the environment worldwide is an insidious and silent process. Thus, unwittingly consumers encounter resistant bacteria in their meat, poultry, fish, and vegetables. Unregulated dispensing of antibiotics in poorer countries breeds countless more resistant strains. Since bacteria recognize no geographical boundaries, resistant forms can travel the globe. If this trend continues to grow unchecked, we may someday find that all of our antibiotics are obsolete. Today doctors can no longer expect that their first choice of antibiotic for women's urinary tract infections or children's ear infections will work. Similarly, cancer therapy is rendered useless if patients are unable to fight infections that are sometimes resistant to eight to ten different drugs. In developing countries, people are now dying of previously treatable diseases that are no longer responsive to traditional antibiotics. These problems are just a harbinger of what will come if we do not act now. Dr. Levy, recognized by The New Yorker for his superb contributions to this field, is sending out an urgent message that the world cannot afford to ignore any longer. The goal of this unprecedented investigation into the dangers of antibiotic misuse is to protect the world community from resistant infections and ensure the success of antibiotics for generations to come