Virus Dynamics Mathematical Principles Of Immunology And Virology

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Virus Dynamics : Mathematical Principles of Immunology and Virology

Author : Martin Nowak
Publisher : Oxford University Press, UK
ISBN 13 : 0191588512
Total Pages : 253 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Virus Dynamics : Mathematical Principles of Immunology and Virology by : Martin Nowak

Download or read book Virus Dynamics : Mathematical Principles of Immunology and Virology written by Martin Nowak and published by Oxford University Press, UK. This book was released on 2000-11-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

Virus Dynamics

Author : Martin A. Nowak
Publisher : Oxford University Press
ISBN 13 : 0198504179
Total Pages : 253 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Virus Dynamics by : Martin A. Nowak

Download or read book Virus Dynamics written by Martin A. Nowak and published by Oxford University Press. This book was released on 2000-11-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals insights into the dynamics of viral & other infections.

Principles of Virology

Author : Jane Flint
Publisher : John Wiley & Sons
ISBN 13 : 1683673581
Total Pages : 4574 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Principles of Virology by : Jane Flint

Download or read book Principles of Virology written by Jane Flint and published by John Wiley & Sons. This book was released on 2020-09-02 with total page 4574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to understand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.

Principles of Virology, Volume 2

Author : S. Jane Flint
Publisher : John Wiley & Sons
ISBN 13 : 1683673360
Total Pages : 1104 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Principles of Virology, Volume 2 by : S. Jane Flint

Download or read book Principles of Virology, Volume 2 written by S. Jane Flint and published by John Wiley & Sons. This book was released on 2015-08-03 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Virology Fourth Edition Principles of Virology is the leading virology textbook because it does more than collect and present facts about individual viruses. Instead, it facilitates an understanding of basic virology by examining the shared processes and capabilities of viruses. Using a set of representative viruses to present the complexity and diversity of a myriad of viruses, this rational approach enables students to understand how reproduction is accomplished by known viruses and provides the tools for future encounters with new or understudied viruses. This fully updated edition represents the rapidly changing field of virology. A major new feature is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology. Applicable courses: undergraduate courses in virology and microbiology as well as graduate courses in virology and infectious diseases.

Killer Cell Dynamics

Author : Dominik Wodarz
Publisher : Springer Science & Business Media
ISBN 13 : 0387687335
Total Pages : 226 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Killer Cell Dynamics by : Dominik Wodarz

Download or read book Killer Cell Dynamics written by Dominik Wodarz and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

Mathematical Immunology of Virus Infections

Author : Gennady Bocharov
Publisher : Springer
ISBN 13 : 3319723170
Total Pages : 256 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Mathematical Immunology of Virus Infections by : Gennady Bocharov

Download or read book Mathematical Immunology of Virus Infections written by Gennady Bocharov and published by Springer. This book was released on 2018-06-12 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph concisely but thoroughly introduces the reader to the field of mathematical immunology. The book covers first basic principles of formulating a mathematical model, and an outline on data-driven parameter estimation and model selection. The authors then introduce the modeling of experimental and human infections and provide the reader with helpful exercises. The target audience primarily comprises researchers and graduate students in the field of mathematical biology who wish to be concisely introduced into mathematical immunology.

Principles of Virology, Volume 1

Author : S. Jane Flint
Publisher : John Wiley & Sons
ISBN 13 : 1683673379
Total Pages : 1477 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Principles of Virology, Volume 1 by : S. Jane Flint

Download or read book Principles of Virology, Volume 1 written by S. Jane Flint and published by John Wiley & Sons. This book was released on 2015-08-03 with total page 1477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Virology is the leading virology textbook because it does more than collect and present facts about individual viruses. Instead, it facilitates an understanding of basic virology by examining the shared processes and capabilities of viruses. Using a set of representative viruses to present the complexity and diversity of a myriad of viruses, this rational approach enables students to understand how reproduction is accomplished by known viruses and provides the tools for future encounters with new or understudied viruses. This fully updated edition represents the rapidly changing field of virology. A major new feature is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology. Applicable courses: undergraduate courses in virology and microbiology as well as graduate courses in virology and infectious diseases.

Introduction to Modern Virology

Author : Nigel J. Dimmock
Publisher : John Wiley & Sons
ISBN 13 : 1119978106
Total Pages : 549 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Introduction to Modern Virology by : Nigel J. Dimmock

Download or read book Introduction to Modern Virology written by Nigel J. Dimmock and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praised forits clarity of presentation and accessibility, Introduction to Modern Virology has been a successful student text for over 30 years. It provides a broad introduction to virology, which includes the nature of viruses, the interaction of viruses with their hosts and the consequences of those interactions that lead to the diseases we see. This new edition contains a number of important changes and innovations including: The consideration of immunology now covers two chapters, one on innate immunity and the other on adaptive immunity, reflecting the explosion in knowledge of viral interactions with these systems. The coverage of vaccines and antivirals has been expanded and separated into two new chapters to reflect the importance of these approaches to prevention and treatment. Virus infections in humans are considered in more detail with new chapters on viral hepatitis, influenza, vector-borne diseases, and exotic and emerging viral infections, complementing an updated chapter on HIV. The final section includes three new chapters on the broader aspects of the influence of viruses on our lives, focussing on the economic impact of virus infections, the ways we can use viruses in clinical and other spheres, and the impact that viruses have on the planet and almost every aspect of our lives. A good basic understanding of viruses is important for generalists and specialists alike. The aim of this book is to make such understanding as accessible as possible, allowing students across the biosciences spectrum to improve their knowledge of these fascinating entities.

Viral Infections of Humans

Author : Alfred S. Evans
Publisher : Springer Science & Business Media
ISBN 13 : 1468447270
Total Pages : 744 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Viral Infections of Humans by : Alfred S. Evans

Download or read book Viral Infections of Humans written by Alfred S. Evans and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.

Virology

Author : John Carter
Publisher : John Wiley & Sons
ISBN 13 : 0470023864
Total Pages : 383 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Virology by : John Carter

Download or read book Virology written by John Carter and published by John Wiley & Sons. This book was released on 2007-08-15 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents an accessible introduction to this fast moving field, providing a comprehensive resource enabling students to understand the key concepts surrounding virology. The authors have produced a text that stimulates and encourages the student through the extensive use of clear, colour-coded diagrams.

An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology

Author : James Sneyd
Publisher : American Mathematical Soc.
ISBN 13 : 9780821867648
Total Pages : 196 pages
Book Rating : 4.8/5 (676 download)

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Book Synopsis An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology by : James Sneyd

Download or read book An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology written by James Sneyd and published by American Mathematical Soc.. This book was released on with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many respects, biology is the new frontier for applied mathematicians. This book demonstrates the important role mathematics plays in the study of some biological problems. It introduces mathematicians to the biological sciences and provides enough mathematics for bioscientists to appreciate the utility of the modelling approach. The book presents a number of diverse topics, such as neurophysiology, cell biology, immunology, and human genetics. It examines how research is done,what mathematics is used, what the outstanding questions are, and how to enter the field. Also given is a brief historical survey of each topic, putting current research into perspective. The book is suitable for mathematicians and biologists interested in mathematical methods in biology.

Case Studies in Systems Biology

Author : Pavel Kraikivski
Publisher : Springer Nature
ISBN 13 : 3030677427
Total Pages : 310 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Case Studies in Systems Biology by : Pavel Kraikivski

Download or read book Case Studies in Systems Biology written by Pavel Kraikivski and published by Springer Nature. This book was released on 2021-10-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relevant details with regard to cell physiology and molecular mechanisms? How are the details put together into a mathematical model? How is the model analyzed and simulated? What are the results of the model? How do they compare to the known facts of the cell physiology? Does the model make predictions? What can be done to extend the model? The book presents a summary of results and references to more relevant sources. The volume contains the classic collection of topics and studies that are well established yet novel in the systems biology field.

Advances in Epidemiological Modeling and Control of Viruses

Author : Hemen Dutta
Publisher : Elsevier
ISBN 13 : 0323995586
Total Pages : 392 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Epidemiological Modeling and Control of Viruses by : Hemen Dutta

Download or read book Advances in Epidemiological Modeling and Control of Viruses written by Hemen Dutta and published by Elsevier. This book was released on 2023-01-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Epidemiological Modeling and Control of Viruses covers recent and advanced research works in the field of epidemiological modeling, with special emphasis on new strategies to control the occurrence and reoccurrence of viruses. The models included in this book can be used to study the dynamics of different viruses, searching for control measures, and epidemic models under various effects and environments. This book covers different models and methods of modeling, including data-driven approaches. The authors and editors are experienced researchers, and each chapter has been designed to provide readers with leading-edge information on topics discussed. Includes models to describe global and local dynamics of various viruses Provides readers with control strategies for occurrence and reoccurrence of viruses Includes epidemic models under various effects and environments Provides readers with a robust set of mathematical tools and techniques for epidemiological modeling

Systems Immunology

Author : Jayajit Das
Publisher : CRC Press
ISBN 13 : 1498717411
Total Pages : 355 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Systems Immunology by : Jayajit Das

Download or read book Systems Immunology written by Jayajit Das and published by CRC Press. This book was released on 2018-09-03 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." –Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.

Quantitative Methods for HIV/AIDS Research

Author : Cliburn Chan
Publisher : CRC Press
ISBN 13 : 1498734251
Total Pages : 309 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Quantitative Methods for HIV/AIDS Research by : Cliburn Chan

Download or read book Quantitative Methods for HIV/AIDS Research written by Cliburn Chan and published by CRC Press. This book was released on 2017-08-07 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.

Fundamental Virology

Author : Bernard N. Fields
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781702843
Total Pages : 0 pages
Book Rating : 4.7/5 (28 download)

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Book Synopsis Fundamental Virology by : Bernard N. Fields

Download or read book Fundamental Virology written by Bernard N. Fields and published by Lippincott Williams & Wilkins. This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

COVID-19 Epidemiology and Virus Dynamics

Author : Till D. Frank
Publisher : Springer Nature
ISBN 13 : 3030971783
Total Pages : 367 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis COVID-19 Epidemiology and Virus Dynamics by : Till D. Frank

Download or read book COVID-19 Epidemiology and Virus Dynamics written by Till D. Frank and published by Springer Nature. This book was released on 2022-03-30 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the COVID-19 pandemic from a quantitative perspective based on mathematical models and methods largely used in nonlinear physics. It aims to study COVID-19 epidemics in countries and SARS-CoV-2 infections in individuals from the nonlinear physics perspective and to model explicitly COVID-19 data observed in countries and virus load data observed in COVID-19 patients. The first part of this book provides a short technical introduction into amplitude spaces given by eigenvalues, eigenvectors, and amplitudes.In the second part of the book, mathematical models of epidemiology are introduced such as the SIR and SEIR models and applied to describe COVID-19 epidemics in various countries around the world. In the third part of the book, virus dynamics models are considered and applied to infections in COVID-19 patients. This book is written for researchers, modellers, and graduate students in physics and medicine, epidemiology and virology, biology, applied mathematics, and computer sciences. This book identifies the relevant mechanisms behind past COVID-19 outbreaks and in doing so can help efforts to stop future COVID-19 outbreaks and other epidemic outbreaks. Likewise, this book points out the physics underlying SARS-CoV-2 infections in patients and in doing so supports a physics perspective to address human immune reactions to SARS-CoV-2 infections and similar virus infections.