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Vip Pacap Glucagon And Related Peptides
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Book Synopsis VIP, PACAP, GLUCAGON, and Related Peptides by : Jan Fahrenkrug
Download or read book VIP, PACAP, GLUCAGON, and Related Peptides written by Jan Fahrenkrug and published by . This book was released on 2000 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, an international group of experts presents research on the biology, biochemistry, molecular biology, physiology and pharmacology of the growing class of peptides that function as hormones or neurotransmitters, including vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide (PACAP), glucagon, and related peptides. Topics include the role of this family of peptides and their receptors in signal transduction mechanisms, cancer, autonomic physiology, neurobiology, cell proliferation, cell death and tissue injury, endocrinology, and neuroimmunology, along with clinical and potential therapeutic implications.
Book Synopsis VIP, PACAP, and Related Peptides by : Akira Arimura
Download or read book VIP, PACAP, and Related Peptides written by Akira Arimura and published by . This book was released on 1996 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research findings on vascular intestinal peptide (VIP), pituitary adenyl cyclase activating peptide (PACAP), and other members of the secretin/glucagon family of peptides are reported by leaders in the field. The role of these peptides in the regulation of gene expression, developmental and neurotrophic processes, as well as endocrine and gastrointestinal functions are addressed and their basic clinical implications discussed.
Book Synopsis VIP, PACAP, and Related Peptides by : Wolf-Georg Forssmann
Download or read book VIP, PACAP, and Related Peptides written by Wolf-Georg Forssmann and published by . This book was released on 1998 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume of papers research findings on vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide (PACAP), and related peptides are presented. The authors provide information on the biology, biochemistry, molecular biology, physiology, signal transduction mechanisms, and pharmacology of these peptides. Their roles in neurobiology, cell proliferation and tumorogenesis, inflammation and tissue injury, endocrinology, gastrointestinal function, and other topics are discussed, along with clinical and potential therapeutic implications.
Book Synopsis From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors by :
Download or read book From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors written by and published by Academic Press. This book was released on 2020-05-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Book Synopsis Vasoactive Intestinal Peptides Pituitary Adenylate Cyclase Activating Polypeptide And Related Regulatory Peptides: From Molecular Biology To Clinical Applications by : G Rosselin
Download or read book Vasoactive Intestinal Peptides Pituitary Adenylate Cyclase Activating Polypeptide And Related Regulatory Peptides: From Molecular Biology To Clinical Applications written by G Rosselin and published by World Scientific. This book was released on 1994-06-21 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most up-to-date information on the ever-growing class of peptides with high biological activity, which function as hormones or neurotransmitters and have analogous structures. These peptides include the Vasoactive Intestinal Peptide (VIP), the Pituitary Adenylate Cyclase-Activating Polypeptides (PACAP 38 and PACAP 27), the Peptide Histidyl-Isoleucylamide and the Histidyl-Methionine Peptide (PHI and PHM), Helodermin, Helospectin, the Growth Hormone Releasing Factor (GRF), Glucagon, the Glucagon-like Peptides I and II, Oxyntomodulin, Glicentin and Secretin.Selection, organization and special subject matter: The contributors to this volume who are leading experts in their fields, present a valuable synopsis of the significant research in the transduction of the peptide signals, and how it helps to maintain the essential environment for cellular functions and adaptation. Contributions are organized around the molecular systems involved in the normal and altered functions of the central nervous system, the endocrine systems and cellular proliferation. In addition, the book identifies potential sites to be targeted for drug design and therapeutic development in the domain of biosynthesis, inflammation and cardiovascular and digestive diseases.This book draws together information from widely-scattered literature and thus obviates the need for time-consuming research on the part of the readers. It is aimed at an international audience of pharmacologists, physiologists, clinical investigators, biochemists and researchers.
Book Synopsis Handbook of Neuroendocrinology by : George Fink
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Book Synopsis Pituitary Adenylate Cyclase Activating Polypeptide — PACAP by : Dora Reglodi
Download or read book Pituitary Adenylate Cyclase Activating Polypeptide — PACAP written by Dora Reglodi and published by Springer. This book was released on 2016-10-08 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive book to cover all aspects of the last 25 years of PACAP (pituitary adenylate cyclase activating polypeptide) research, this book contains contributions from virtually all the leading researchers in the field, and addresses some of the following topics: evolutionary aspects of PACAP, distribution and occurrence of PACAP and its receptors, hormonal effects of PACAP, intracellular signaling, effects on cellular proliferation and differentiation, protective effects of PACAP, behavioral effects of PACAP, developmental aspects of PACAP, other physiological effects of PACAP (cardiovascular, thermoregulatory), human studies, drug design, metabolism and transport. This compendium can serve as an important reference for researchers and students in PACAP research and can also be a thorough introduction for those in related fields.
Book Synopsis Cellular Peptide Hormone Synthesis and Secretory Pathways by : Jens F. Rehfeld
Download or read book Cellular Peptide Hormone Synthesis and Secretory Pathways written by Jens F. Rehfeld and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.
Book Synopsis Stress: Physiology, Biochemistry, and Pathology by : George Fink
Download or read book Stress: Physiology, Biochemistry, and Pathology written by George Fink and published by Academic Press. This book was released on 2019-01-12 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress impacts the daily lives of humans and all species on Earth. Physiology, Biochemistry, and Pathology, the third volume of the Handbook of Stress series, covers stress-related or induced physiology, biochemistry, and pathology. Integrated closely with new behavioral findings and relevance to human conditions, the concepts and data in this volume offer readers cutting-edge information on the physiology of stress. A sequel to Elsevier’s Encyclopedia of Stress (2000 and 2007), this Handbook of Stress series covers the many significant advances made since then and comprises self-contained volumes that each focus on a specific area within the field of stress. Targeted at scientific and clinical researchers in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry, the social sciences, and stress and its management in the workplace, this volume and series are ideal for graduate students, post-doctoral fellows, and faculty interested in stress and its consequences. Chapters offer impressive scope, with topics addressing stress-related or induced physiology, biochemistry, and pathology Articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field, with each chapter fully vetted for reliable expert knowledge Richly illustrated with explanatory figures and tables Each chapter has a boxed “Key points call out section The volume is fully indexed All chapters are electronically available via ScienceDirect Affordably priced, self-contained volume for readers specifically interested in the physiology, biochemistry and pathology of stress, avoiding the need to purchase the whole Handbook series
Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin
Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.
Book Synopsis Physiological Aspects of Digestion and Metabolism in Ruminants by : T. Tsuda
Download or read book Physiological Aspects of Digestion and Metabolism in Ruminants written by T. Tsuda and published by Academic Press. This book was released on 2012-12-02 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is comprised of invited papers presented at the Seventh International Symposium on Ruminant Physiology, held in Sendai, Japan, in September 1989. Papers are invited on the recommendations of 300 international experts. The proceedings of this symposia provides the most comprehensive coverage available of current research in ruminant physiology.
Book Synopsis Developmental Biology of Gastrointestinal Hormones by : M. Wabitsch
Download or read book Developmental Biology of Gastrointestinal Hormones written by M. Wabitsch and published by Karger Medical and Scientific Publishers. This book was released on 2017-08-16 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gut not only represents the largest endocrine organ of the human body but is also profoundly involved in the control of metabolism through peptide hormones. Therefore, gastrointestinal hormones are acting via autocrine, paracrine, and classical endocrine pathways and regulate e.g. digestion, hunger, and satiety. Furthermore, they are important regulators of body weight, growth, and glucose metabolism, as well as of mood and behavior. Physicians and scientists in the field of pediatric endocrinology and diabetes, as well as in pediatric gastroenterology, require an extensive understanding of the origin of enteroendocrine cells, factors controlling their differentiation, hormone gene expression, secretion, function and, finally, the complex interaction with other organs, especially the central nervous system. In order to meet these needs, experts in the field have written up-to-date, comprehensive, and illustrated reviews presenting the current knowledge in the field of gastrointestinal endocrinology with a pediatric view. Those reviews comprise this latest volume of Endocrine Development.
Book Synopsis Autonomic Nervous System by : Daniel Pedro Cardinali
Download or read book Autonomic Nervous System written by Daniel Pedro Cardinali and published by Springer. This book was released on 2017-08-04 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: A traditional view of the Autonomic Nervous System (ANS) considers only its peripheral part: the sympathetic and parasympathetic systems. However, this view misses to consider the most important ANS function: the maintenance of homeostasis. This term is used today to define not only the strategies that allow the body proper response to changes in the environment (reactive homeostasis), but also temporal mechanisms that allow the body to predict the most likely timing of environmental stimuli (predictive homeostasis based on biological rhythms). This book discusses the ANS from both an enlarged and a timed perspective. First, it presents how the organization of the ANS is hierarchical into different levels. Following that, the book discusses how the ANS changes functionally in the three-body configurations (wakefulness, slow sleep, rapid eye movement sleep) found in a 24-hour cycle. Finally, the most important clinical implications of this enlarged and timed vision of ANS will be discussed. Autonomic Nervous System – Basic and Clinical Aspects is a comprehensive text intended for medical students and health professionals who are interested in a deeper approach to this important part of the nervous system. It provides a detailed and complete understanding of the neuroscience behind the ANS, allowing a proper clinical applicability of this knowledge.
Book Synopsis Circadian Rhythms and Biological Clocks Part A by :
Download or read book Circadian Rhythms and Biological Clocks Part A written by and published by Academic Press. This book was released on 2015-01-30 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Keeping with the interdisciplinary nature of the circadian rhythm field, the volume includes diverse approaches towards the study of rhythms, from assays of biochemical reactions in unicellular organisms to monitoring of behavior in humans.
Book Synopsis Neuroendocrine Control of Feeding Behavior by : Serge H. Luquet
Download or read book Neuroendocrine Control of Feeding Behavior written by Serge H. Luquet and published by Frontiers Media SA. This book was released on 2019-11-20 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamus plays a crucial role in the regulation of food intake and energy homeostasis. Hypothalamic neuronal circuits thus represent a privileged target for the treatment of eating disorders and metabolic diseases. The present eBook constitutes a unique collection of research articles and reviews that highlight new concepts and recent findings about the neuroendocrine control of feeding behavior.
Book Synopsis VIP, PACAP, and Related Peptides by : Hubert Vaudry
Download or read book VIP, PACAP, and Related Peptides written by Hubert Vaudry and published by Wiley-Blackwell. This book was released on 2006-08-07 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview on the biochemistry, physiology, and pharmacology of vasoactive intestinal polypeptide (VIP), pituitary adenylate cyclase-activating polypeptide (PACAP), and related peptides. VIP and PACAP are undoubtedly among the most fascinating neuropeptides ever identified. They belong to the largest family of regulatory peptides, which comprises several other prominent neuroendocrine peptides including secretin (the first peptide hormone that has been identified), glucagon, and growth hormone-releasing hormone. The structural and physiological relationships of these peptides as well as their receptors provide a unique model for investigating the processes of molecular evolution leading to the diversification of multigene families. The primary structures of VIP and PACAP have been remarkably well conserved across vertebrates, suggesting that these peptides must be involved in vital functions throughout the animal kingdom. Indeed, VIP and PACAP appear to be implicated in a large array of physiological processes such as development; growth; endocrine, cardiovascular, respiratory, reproductive and digestive functions; immune responses; and circadian rhythms. There is also clear evidence that VIP and PACAP exert both trophic and antiproliferative effects on normal and tumor cells. The beneficial influence of VIP and PACAP agonists and antagonists in various pathological states including heart failure, ischemia, asthma, impotence, and cancer has motivated the development of novel selective VIP or PACAP ligands that could potentially be used as antihypertensive, neuroprotective, bronchodilatory, vasodilatory, and/or antiproliferative drugs. The occurrence of multiple VIP/PACAP receptor subtypes and splice variants that exhibit tissue-specific expression and possess differential affinity for various ligands generates hopes for the development of new therapeutic agents that could act selectively on the desired target cells. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Book Synopsis Suprachiasmatic Nucleus by : David C. Klein
Download or read book Suprachiasmatic Nucleus written by David C. Klein and published by Oxford University Press, USA. This book was released on 1991 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a conference funded by the National Institutes of Health, this timely book is the most up-to-date and definitive reference on the suprachiasmatic nucleus (SCN), the part of the brain that controls circadian rhythms in mammals. These biological rhythms range from daily fluctuations in metabolism to seasonal and annual cycles. This book comprehensive and incisive review of the SCN covers anatomy and physiology, intrinsic SCN rhythms, circadian rhythms, neuropharmacology, transplants, and development.
