Drug Discovery

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Publisher : Springer Science & Business Media
ISBN 13 : 1461204690
Total Pages : 443 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Drug Discovery by : Robert A. Maxwell

Download or read book Drug Discovery written by Robert A. Maxwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers some close confreres of the authors, others more distant-believed otherwise. We felt that their view reflected unrealistic thinking and that reality probably lay closer to what Beyer" maintained: We are taught to believe that if we can understand a disease it should be easy enough to figure out, say, the molecular configuration of a definitive receptor mechanism somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were discovered. There were only anecdotal accounts, and these were able to be selected and presented in ways that could be used to defend any point of view.

Current Concepts of External Fixation of Fractures

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Publisher : Springer
ISBN 13 : 9783642684500
Total Pages : 0 pages
Book Rating : 4.6/5 (845 download)

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Book Synopsis Current Concepts of External Fixation of Fractures by : Hans K. Uhthoff

Download or read book Current Concepts of External Fixation of Fractures written by Hans K. Uhthoff and published by Springer. This book was released on 2011-12-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: External fixation is now being used widely to maintain fractures, osteo tomies, and arthrodeses in a desired position during consolidation. Whereas external fixation has been readily accepted in European countries, its use has weathered a rather stormy course in North America, especially in the treatment of fractures. Only recently has external fixation found its rightful place on this continent as well. Many different models are on the market today, and the practitioner is faced with a difficult decision in selecting a model. Should he buy a system where the fracture has to be reduced first, or should he work with a device permitting a reduction after insertion of the pins? To enable surgeons to study the different systems, to discuss their advantages and disadvantages, and to permit them to put their hands on these devices and inspect them personally, the Division of Orthopedic Surgery, University of Ottawa organized an applied basic science course in May 1981, External Fixation of Fractures. During this course, all major systems were pre sented to the participants. As happened during the course "Internal Fixation of Fractures" held two years ago, the rigidity of internal fixation was frequently and intensively debated. Whereas the rigidity of internal fixation cannot be altered during the course of healing, the rigidity of external fixation can be changed. In fact, with progression of union, rods of increasing elasticity can be used.

Platform Chemical Biorefinery

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Publisher : Elsevier
ISBN 13 : 0128030046
Total Pages : 530 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Platform Chemical Biorefinery by : Satinder Kaur Brar

Download or read book Platform Chemical Biorefinery written by Satinder Kaur Brar and published by Elsevier. This book was released on 2016-06-02 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Chemical Biorefinery: Future Green Chemistry provides information on three different aspects of platform chemical biorefinery. The book first presents a basic introduction to the industry beneficial for university students, then provides engineering details of existing or potential platform chemical biorefinery processes helpful to technical staff of biorefineries. Finally, the book presents a critical review of the entire platform chemical biorefinery process, including extensive global biorefinery practices and their potential environmental and market-related consequences. Platform chemicals are building blocks of different valuable chemicals. The book evaluates the possibility of renewable feedstock-based platform chemical production and the fundamental challenges associated with this objective. Thus, the book is a useful reference for both academic readers and industry technical workers. The book guides the research community working in the field of platform chemical biorefinery to develop new pathways and technologies in combination with their market value and desirability. - Offers comprehensive coverage of platform chemicals biorefineries, recent advances and technology developments, potential issues for preventing commercialization, and solutions - Discusses existing technologies for platform chemicals production, highlighting benefits as well their possible adverse effects on the environment and food security - Includes a global market analysis of platform chemicals and outlines industry opportunities - Serves as a useful reference for both academic readers and industry technical workers

Nanomaterials in the Environment

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Publisher : ASCE Press
ISBN 13 : 9780784414088
Total Pages : 642 pages
Book Rating : 4.4/5 (14 download)

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Book Synopsis Nanomaterials in the Environment by : Satinder Kaur Brar

Download or read book Nanomaterials in the Environment written by Satinder Kaur Brar and published by ASCE Press. This book was released on 2015-10-01 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the most current knowledge on the environmental impact of materials and products developed using nanotechnology. Although nanomaterials are revolutionising electronics, medicine, transportation and many other industries, they pose risks to living beings and ecosystems that are barely understood. Leading researchers here consider the science of nanomaterials, their behaviour in the environment, risk assessment and toxicology, and the future of nanomaterials.

Statistical Methods in Agriculture and Experimental Biology

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Publisher : CRC Press
ISBN 13 : 1351414283
Total Pages : 490 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Statistical Methods in Agriculture and Experimental Biology by : Roger Mead

Download or read book Statistical Methods in Agriculture and Experimental Biology written by Roger Mead and published by CRC Press. This book was released on 2017-11-22 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this popular introductory text maintains the character that won worldwide respect for its predecessors but features a number of enhancements that broaden its scope, increase its utility, and bring the treatment thoroughly up to date. It provides complete coverage of the statistical ideas and methods essential to students in agriculture or experimental biology. In addition to covering fundamental methodology, this treatment also includes more advanced topics that the authors believe help develop an appreciation of the breadth of statistical methodology now available. The emphasis is not on mathematical detail, but on ensuring students understand why and when various methods should be used. New in the Third Edition: A chapter on the two simplest yet most important methods of multivariate analysis Increased emphasis on modern computer applications Discussions on a wider range of data types and the graphical display of data Analysis of mixed cropping experiments and on-farm experiments

Clinical Chronopharmacology

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Publisher : CRC Press
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Clinical Chronopharmacology by : Alain Reinberg

Download or read book Clinical Chronopharmacology written by Alain Reinberg and published by CRC Press. This book was released on 1990-07 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periodical and predictable changes in biological susceptibility and response to a large variety of chemical agents, including drugs and food, have been documented since the early 1970s. This book provides a survey of clinically-documented research in chronopharmacology.

Color Atlas of Equine Pathology

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Publisher : John Wiley & Sons
ISBN 13 : 0470962844
Total Pages : 565 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Color Atlas of Equine Pathology by : Claus D. Buergelt

Download or read book Color Atlas of Equine Pathology written by Claus D. Buergelt and published by John Wiley & Sons. This book was released on 2014-01-28 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Color Atlas of Equine Pathology offers a practical guide to identifying equine diseases, presenting a single resource with more than 1000 images showing predominantly gross pathology. Organized by body systems, the book allows for picture matching during or after an equine necropsy. In this user-friendly atlas, each chapter takes a common format, presenting the disease process as well as congenital, degenerative, inflammatory, and neoplastic sequences, with text boxes offering quick reference to key information. The book begins with an introductory chapter summarizing the principles of the equine field necropsy, and subsequent organ-based chapters depict gross features of disease, focusing on macroscopic digital images supplemented by histology and immunohistochemistry when necessary. Some clinical information for correlation with pathology is included. Color Atlas of Equine Pathology is an essential resource for diagnostic veterinary pathologists and pathology residents, as well as for equine practitioners performing necropsies in the field.

An Introduction to Differential Manifolds

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Publisher : Springer
ISBN 13 : 3319207350
Total Pages : 408 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis An Introduction to Differential Manifolds by : Jacques Lafontaine

Download or read book An Introduction to Differential Manifolds written by Jacques Lafontaine and published by Springer. This book was released on 2015-07-29 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to differential manifolds. It gives solid preliminaries for more advanced topics: Riemannian manifolds, differential topology, Lie theory. It presupposes little background: the reader is only expected to master basic differential calculus, and a little point-set topology. The book covers the main topics of differential geometry: manifolds, tangent space, vector fields, differential forms, Lie groups, and a few more sophisticated topics such as de Rham cohomology, degree theory and the Gauss-Bonnet theorem for surfaces. Its ambition is to give solid foundations. In particular, the introduction of “abstract” notions such as manifolds or differential forms is motivated via questions and examples from mathematics or theoretical physics. More than 150 exercises, some of them easy and classical, some others more sophisticated, will help the beginner as well as the more expert reader. Solutions are provided for most of them. The book should be of interest to various readers: undergraduate and graduate students for a first contact to differential manifolds, mathematicians from other fields and physicists who wish to acquire some feeling about this beautiful theory. The original French text Introduction aux variétés différentielles has been a best-seller in its category in France for many years. Jacques Lafontaine was successively assistant Professor at Paris Diderot University and Professor at the University of Montpellier, where he is presently emeritus. His main research interests are Riemannian and pseudo-Riemannian geometry, including some aspects of mathematical relativity. Besides his personal research articles, he was involved in several textbooks and research monographs.

Biological Rhythm Research

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Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biological Rhythm Research by : A. Sollberger

Download or read book Biological Rhythm Research written by A. Sollberger and published by . This book was released on 1965 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Minimum Competence in Scientific English

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Publisher :
ISBN 13 : 9782706104084
Total Pages : 254 pages
Book Rating : 4.1/5 (4 download)

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Book Synopsis Minimum Competence in Scientific English by : Susan Blattès

Download or read book Minimum Competence in Scientific English written by Susan Blattès and published by . This book was released on 1991 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le présent ouvrage répond à un objectif précis : être un outil efficace pour ceux qui sont confrontés à des textes en anglais scientifique. Minimum Competence in Scientific English suppose, pour ses utilisateurs, des prérequis de niveau baccalauréat. Il peut être utilisé en autoformation. Les étudiants scientifiques sont évidemment les premiers concernés, mais l'expérience a démontré que les chercheurs, les ingénieurs, les enseignants, les managers, confrontés aux subtilités de l'anglais scientifique écrit, étaient demandeurs de tels ouvrages.

Endocrine Rhythms

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Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Endocrine Rhythms by : Dorothy T. Krieger

Download or read book Endocrine Rhythms written by Dorothy T. Krieger and published by . This book was released on 1979 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Primary Orthopedic Care

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Publisher :
ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Primary Orthopedic Care by : Christy L. Crowther

Download or read book Primary Orthopedic Care written by Christy L. Crowther and published by . This book was released on 2004 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary Orthopedic Care, 2nd Edition offers the most practical approach to common orthopedic disorders in the primary care setting. Content is organized from upper to lower extremities, beginning with symptoms rather than a diagnosis for use in the patient care setting. Nine major orthopedic areas are thoroughly covered, as well as injections for musculoskeletal disorders. Presentation and history, the most crucial diagnostic tools, are discussed in a separate section within each orthopedic area. In addition, anatomy and physiology, examination, diagnosis (including imaging modalities) and treatment are consistently covered in each region. Its emphasis on differential diagnosis, with clear cautions indicating when to refer a patient to a specialist, make this book a valuable guide for nurse practitioners in primary care.

Eat Sleep Bagpipes Repeat

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Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781723229053
Total Pages : 104 pages
Book Rating : 4.2/5 (29 download)

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Book Synopsis Eat Sleep Bagpipes Repeat by : Mirako Press

Download or read book Eat Sleep Bagpipes Repeat written by Mirako Press and published by Createspace Independent Publishing Platform. This book was released on 2018-07-18 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This adorable music notebook is perfect for staffs, kids and musicians. The high-quality manuscript book includes 110 pages of 12 staves. Let exercise your composing skills with this well-designed music sketchbook! Enjoy!

Materials Syntheses

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Publisher : Springer Science & Business Media
ISBN 13 : 3211751254
Total Pages : 220 pages
Book Rating : 4.2/5 (117 download)

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Book Synopsis Materials Syntheses by : Ulrich Schubert

Download or read book Materials Syntheses written by Ulrich Schubert and published by Springer Science & Business Media. This book was released on 2008-11-23 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials syntheses are more complex than syntheses of inorganic or organic compounds. Materials synthesis protocols often suffer from unclarities, irreproducibility, lack in detail and lack in standards. The need to change this situation is the main motivation for this book. It collects a number of detailed protocols, ranging from organic polymers to carbonaceous and ceramic materials, from gels to porous and layered materials and from powders and nanoparticles to films.

Xeroradiography of the Breast

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Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Xeroradiography of the Breast by : John N. Wolfe

Download or read book Xeroradiography of the Breast written by John N. Wolfe and published by . This book was released on 1972 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Characterization and Performance of Calcium Phosphate Coatings for Implants

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Publisher :
ISBN 13 : 9780803118546
Total Pages : 212 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Characterization and Performance of Calcium Phosphate Coatings for Implants by :

Download or read book Characterization and Performance of Calcium Phosphate Coatings for Implants written by and published by . This book was released on 1911 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Developments and Applications of Calcium Phosphate Bone Cements

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Publisher : Springer
ISBN 13 : 9811059756
Total Pages : 632 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Developments and Applications of Calcium Phosphate Bone Cements by : Changsheng Liu

Download or read book Developments and Applications of Calcium Phosphate Bone Cements written by Changsheng Liu and published by Springer. This book was released on 2017-10-20 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.