Use Of Novel Techniques To Quantify Phenotypes In Biological Treatment Process

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Use of Novel Techniques to Quantify Phenotypes in Biological Treatment Process

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Author : K. G. Robinson
Publisher : IWA Publishing
ISBN 13 : 1843396971
Total Pages : 220 pages
Book Rating : 4.8/5 (433 download)

Book Synopsis Use of Novel Techniques to Quantify Phenotypes in Biological Treatment Process by : K. G. Robinson

Download or read book Use of Novel Techniques to Quantify Phenotypes in Biological Treatment Process written by K. G. Robinson and published by IWA Publishing. This book was released on 2004-01-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research attempts to evaluate nitrification treatment performance in combined carbon/nitrogen municipal wastewater reactors using traditional physical/chemical methods and modern molecular techniques. Bench scale activated sludge reactors were operated at different SRTs under varying DO levels and temperatures over a 21-month period. Real-time PCR assays were used to determine cell concentrations of total bacterial 16S rDNA, a gross measure of biomass content, the amoA gene, a measure of ammonia-oxidizing bacteria (AOB), and the Nitrospira 16S rDNA gene, a measure of nitrite-oxidizing bacteria (NOB). As expected, gravimetric biomass and total bacterial 16S rDNA levels increased with increasing SRT. Ammonia oxidation rates and N. oligotropha-type AOB concentrations did not follow similar trends with respect to changes in SRT, temperature, and DO nor were they highly correlated. The concentration of available nitrite and SRT were positively correlated with Nitrospira cell densities, while DO concentration and temperature were negatively correlated with NOB levels. The percentage of the total population comprised of AOB and NOB obtained with the real-time PCR assays were compared to predicted values estimated from design equations using typical kinetic parameters. While the percentages of NOB measured using the real-time PCR assay corresponded very well with the predicted values, the measured percentages of AOB were much lower than those estimated from the design equations, suggesting that N. oligotropha-type AOB were not the dominant ammonia-oxidizing species in these reactors. This publication can be purchased and downloaded via Pay Per View on Water Intelligence Online - click on the Pay Per View icon below

Evolution of Translational Omics

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Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis

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Author :
Publisher : Academic Press
ISBN 13 : 0128142855
Total Pages : 266 pages
Book Rating : 4.1/5 (281 download)

Book Synopsis Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis by :

Download or read book Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis written by and published by Academic Press. This book was released on 2018-11-22 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids, microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more. - Contains contributions from experts in the field from across the world - Covers a wide array of topics on both mitosis and meiosis - Includes relevant, analysis based topics

Fluorescence Imaging and Biological Quantification

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Author : Raquel Seruca
Publisher : CRC Press
ISBN 13 : 1351647334
Total Pages : 274 pages
Book Rating : 4.3/5 (516 download)

Book Synopsis Fluorescence Imaging and Biological Quantification by : Raquel Seruca

Download or read book Fluorescence Imaging and Biological Quantification written by Raquel Seruca and published by CRC Press. This book was released on 2017-09-06 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.

The Science and Applications of Synthetic and Systems Biology

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Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine

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Author : Alok Pandya
Publisher : Academic Press
ISBN 13 : 032390985X
Total Pages : 316 pages
Book Rating : 4.3/5 (239 download)

Book Synopsis Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine by : Alok Pandya

Download or read book Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine written by Alok Pandya and published by Academic Press. This book was released on 2022-08-04 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning. - Provides a basic understanding of how to design, and implement various self-assembled nanobiomaterials - Covers principles implemented in the constructions of novel nanostructured materials - Offers many applications of self-assemblies in fluorescent biological labels, drug and gene delivery, bio-detection of pathogens, detection of proteins, probing of DNA structure, tissue engineering, and many more

Assess

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Author : Lakhdar Lamari
Publisher :
ISBN 13 : 9780890542965
Total Pages : 0 pages
Book Rating : 4.5/5 (429 download)

Book Synopsis Assess by : Lakhdar Lamari

Download or read book Assess written by Lakhdar Lamari and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer program which performs image analysis for measuring the extent of plant diseases.

Stochastic Processes In Genetics And Evolution: Computer Experiments In The Quantification Of Mutation And Selection

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Author : Charles J Mode
Publisher : World Scientific
ISBN 13 : 9814397075
Total Pages : 695 pages
Book Rating : 4.8/5 (143 download)

Book Synopsis Stochastic Processes In Genetics And Evolution: Computer Experiments In The Quantification Of Mutation And Selection by : Charles J Mode

Download or read book Stochastic Processes In Genetics And Evolution: Computer Experiments In The Quantification Of Mutation And Selection written by Charles J Mode and published by World Scientific. This book was released on 2012-02-13 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of this book is the field of evolutionary genetics. The book contains new methods for simulating evolution at the genomic level. It sets out applications using up to date Monte Carlo simulation methods applied in classical population genetics, and sets out new fields of quantifying mutation and selection at the Mendelian level. A serious limitation of Wright-Fisher process, the assumption that population size is constant, motivated the introduction of self regulating branching processes in this book. While providing a short review of the principles of probability and its application and using computer intensive methods whilst applying these principles, this book explains how it is possible to derive new formulas expressed in terms of matrix algebra providing new insights into the classical Wright-Fisher processes of evolutionary genetics. Also covered are the development of new methods for studying genetics and evolution, simulating nucleotide substitutions of a DNA molecule and on self regulating branching processes. Components of natural selection are studied in terms of reproductive success of each genotype whilst also studying the differential ability of genotypes to compete for resources and sexual selection. The concept of the gene is also reviewed in this book, and it provides a current definition of a gene based on very recent experiments with micro-array technologies. A development of stochastic models for simulating the evolution of model genomes concludes the studies in this book. Deserving of a place on the book shelves of workers in biomathematics, applied probability, stochastic processes and statistics, as well as in bioinformatics and phylogenetics, it will also be relevant to those interested in computer simulation, and evolutionary biologists interested in quantitative methods.

Transforming Agricultural Technology by Artificial Intelligence and Robotics

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Author : Manan Shah
Publisher : CRC Press
ISBN 13 : 1003808964
Total Pages : 184 pages
Book Rating : 4.0/5 (38 download)

Book Synopsis Transforming Agricultural Technology by Artificial Intelligence and Robotics by : Manan Shah

Download or read book Transforming Agricultural Technology by Artificial Intelligence and Robotics written by Manan Shah and published by CRC Press. This book was released on 2023-12-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses major issues in the field of agriculture: crop diseases, lack of storage management, pesticide control, weed management, lack of irrigation and water management and their effective resolution via automation, including IoT, wireless communications, machine learning, artificial intelligence, and deep learning. It further discusses the sterile insect technique, which is a replacement of conventional pesticide and fertilizer techniques. Hydroponics and vertical farming, two of the top-ranked agricultural engineering accomplishments of the past century, are also discussed. Features: Offers in-depth insights regarding the fundamentals of technologies associated with the agriculture sector Synthesizes earlier works of researchers and inventors in this field Sheds light on the challenges and problems of supply and demand worldwide Encourages the reader to innovate and ideate upon those issues Analyses the wide array of services provided by companies worldwide and discusses recent breakthroughs in agriculture automation This book is aimed at the work of many researchers to obtain a concise overview of the current implementation of automation in agriculture and derive important insight into its upcoming challenges.

New Approach Methods in Immunology

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Author : Jeffrey John Bajramovic
Publisher : Frontiers Media SA
ISBN 13 : 2832554989
Total Pages : 258 pages
Book Rating : 4.8/5 (325 download)

Book Synopsis New Approach Methods in Immunology by : Jeffrey John Bajramovic

Download or read book New Approach Methods in Immunology written by Jeffrey John Bajramovic and published by Frontiers Media SA. This book was released on 2024-09-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, the assessment of functional immunological relevance is mainly done in animal models. Motivation to work on non-animal methods, or new approach methods (NAM), stems from economical and ethical considerations, and is supported by public pressure. Importantly, the translational gap between results obtained in animal studies and clinical trials in humans (the ‘valley of death’), combined with the reproducibility crisis in science, also provide strong scientific arguments to work on novel, robust, human-based methodology. The field of immunology confronts NAM scientists with specific challenges. Firstly, immunological responses require several cell types in different locations for proper development and take considerable time to develop. Secondly, immunological responses in outbred humans are characterized by genetic and functional variability. Still, the development and application of NAM are increasing rapidly, and the field is moving at such a fast pace that a special issue is timely. Our goal is to provide an overview of the current state-of-the-art regarding new approach methods or non-animal methods (NAM) in immunology. These should be inspired by the desire to mimic in vivo biology and describe e.g. challenges in mimicking immunological structures (like lymph nodes, bone marrow, local immune structures), immunological responses (systemic and local, innate and adaptive, B cells and T cells) and/or immunological processes (like maturation, trafficking, extravasation, immunotoxicity, affinity maturation).

System Biology Methods and Tools for Integrating Omics Data - Volume II

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Author : Liang Cheng
Publisher : Frontiers Media SA
ISBN 13 : 2889769151
Total Pages : 158 pages
Book Rating : 4.8/5 (897 download)

Book Synopsis System Biology Methods and Tools for Integrating Omics Data - Volume II by : Liang Cheng

Download or read book System Biology Methods and Tools for Integrating Omics Data - Volume II written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-09-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Machine Learning Techniques on Gene Function Prediction

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Author : Quan Zou
Publisher : Frontiers Media SA
ISBN 13 : 2889632148
Total Pages : 485 pages
Book Rating : 4.8/5 (896 download)

Book Synopsis Machine Learning Techniques on Gene Function Prediction by : Quan Zou

Download or read book Machine Learning Techniques on Gene Function Prediction written by Quan Zou and published by Frontiers Media SA. This book was released on 2019-12-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Phenotyping of Human iPSC-derived Neurons

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Author : Elizabeth D. Buttermore
Publisher : Academic Press
ISBN 13 : 0128222786
Total Pages : 374 pages
Book Rating : 4.1/5 (282 download)

Book Synopsis Phenotyping of Human iPSC-derived Neurons by : Elizabeth D. Buttermore

Download or read book Phenotyping of Human iPSC-derived Neurons written by Elizabeth D. Buttermore and published by Academic Press. This book was released on 2022-09-09 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification. - Discusses techniques and new technology for iPSC culturing and neuronal differentiation to establish best practices in the lab - Outlines considerations for phenotypic assay development - Provides information about the successes, failures, and implications of phenotyping and screening with iPSC-derived neurons - Describes how human iPSC-derived neurons are being used for preclinical discovery research as well as the development of therapeutics utilizing hiPSC-derived neurons

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

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Author : Richard A. McPherson
Publisher : Elsevier Health Sciences
ISBN 13 : 1455726842
Total Pages : 1769 pages
Book Rating : 4.4/5 (557 download)

Book Synopsis Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book by : Richard A. McPherson

Download or read book Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book written by Richard A. McPherson and published by Elsevier Health Sciences. This book was released on 2011-09-06 with total page 1769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype, Volume II

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Author : Yunpeng Cao
Publisher : Frontiers Media SA
ISBN 13 : 2832544703
Total Pages : 353 pages
Book Rating : 4.8/5 (325 download)

Book Synopsis Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype, Volume II by : Yunpeng Cao

Download or read book Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype, Volume II written by Yunpeng Cao and published by Frontiers Media SA. This book was released on 2024-02-13 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the article collection series - Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype. Horticultural plants play an important role for humans by providing herbal medicines, beverages, vegetables, fruits, and ornamentals. High-throughput technologies have revolutionised the time scale and power of detecting insights into physiological changes and biological mechanisms in plants. All sequencing data and tools have helped us better understand the evolutionary histories of horticultural plants and provide genotype and phenotype resources for molecular studies on economically important traits. The integration of these -omics technologies (e.g., genomics, transcriptomics, proteomics, metabolomics, lipidomics, ionomics, and redoxomics) is currently at the forefront of plant research. The genomes of horticultural plants are highly diverse and complex, often with a high degree of heterozygosity and polyploidy. Novel computational methods need to be developed to take advantage of state-of-the-art genomic technologies. As a result, the mining of multi-omics data and the development of new computational biology approaches for the reliable and efficient analysis of plant traits is necessary.

Phenotypic Plasticity

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Author : Thomas J. DeWitt
Publisher : Oxford University Press, USA
ISBN 13 : 0195138961
Total Pages : 262 pages
Book Rating : 4.1/5 (951 download)

Book Synopsis Phenotypic Plasticity by : Thomas J. DeWitt

Download or read book Phenotypic Plasticity written by Thomas J. DeWitt and published by Oxford University Press, USA. This book was released on 2004 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic, evolution, adaptation, environment, genotype.

Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II

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Author : Liang Cheng
Publisher : Frontiers Media SA
ISBN 13 : 2832507387
Total Pages : 793 pages
Book Rating : 4.8/5 (325 download)

Book Synopsis Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II by : Liang Cheng

Download or read book Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-11-29 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: