Tularemia Epidemiology Ecology Genomics Immunity And Pathogenesis

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Tularemia: Epidemiology, Ecology, Genomics, Immunity and Pathogenesis

Author : Marina Santic
Publisher : Frontiers Media SA
ISBN 13 : 2889633632
Total Pages : 324 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Tularemia: Epidemiology, Ecology, Genomics, Immunity and Pathogenesis by : Marina Santic

Download or read book Tularemia: Epidemiology, Ecology, Genomics, Immunity and Pathogenesis written by Marina Santic and published by Frontiers Media SA. This book was released on 2020-01-22 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tularemia is a severe anthropozoonosis caused by Francisella tularensis. The genus Francisella contains five species: F. tularensis, F. philomiragia, F. hispaniensis, F. noatunensis and F. novicida. First described in 1911 in Tulare County, California, it has since been reported worldwide, capable of infecting more than 250 vertebrates and invertebrate species. Although it causes disease in various animal species, no animal has been identified as a main reservoir of this pathogen. Humans acquire infection by several routes, including direct contact with infected animals, ingestion of water or food contaminated by infected animals, exposure to infected arthropod vectors or by inhalation of infective aerosols resulting in pneumonic, oropharyngeal, glandular, ulceroglandular or oculoglandular tularemia. The clinical presentation of human tularemia depends on route of the infection, the causative Francisella strain, and the immune response of the host. A live attenuated vaccine (LVS) has been available for more than 50 years, however, unlikely to become licensed in the future due to a lack of understanding of the genetic basis for its attenuation. Due to the ease of its dissemination, its multiple routes of infection, its low dose of infection, severe morbidity, and high rate of mortality, F. tularensis subsp. tularensis has been classified as a category A bioterrorism agent by the CDC. Many virulence factors of F. tularensis have been discovered and investigated, but more in-depth host pathogen interaction analyses are needed to define mechanisms of pathogenicity and virulence of this unique pathogen.

WHO Guidelines on Tularaemia

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241547375
Total Pages : 125 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis WHO Guidelines on Tularaemia by : World Health Organization

Download or read book WHO Guidelines on Tularaemia written by World Health Organization and published by World Health Organization. This book was released on 2007-12-15 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tularaemia is a bacterial zoonotic disease of the northern hemisphere. The bacterium (Francisella tularensis) is highly virulent for humans and a range of animals such as rodents hares and rabbits. Humans can infect themselves by direct contact with infected animals by arthropod bites by ingestion of contaminated water or food or by inhalation of infective aerosols. There is no human-to-human transmission. In addition to its natural occurrence F. tularensis evokes great concern as a potential bioterrorism agent. F. tularensis subspecies tularensis is one of the most infectious pathogens known in human medicine. In order to avoid laboratory-associated infection safety measures are needed and consequently clinical laboratories do not generally accept specimens for culture. However since clinical management of cases depends on early recognition there is an urgent need for diagnostic services. This first edition of WHO Guidelines on tularaemia provides background information on the disease describes the current best practices for its diagnosis and treatments in humans suggests measures to be taken in case of epidemics and provides guidance on how to handle F. tularensis in the laboratory. The target audience includes clinicians laboratory personnel public health workers veterinarians and any other person with an interest in zoonoses.

Emerging Infectious Diseases

Author :
Publisher :
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Emerging Infectious Diseases by :

Download or read book Emerging Infectious Diseases written by and published by . This book was released on 2007 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Common Marmoset in Captivity and Biomedical Research

Author : Robert P. Marini
Publisher : Academic Press
ISBN 13 : 012811830X
Total Pages : 572 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Common Marmoset in Captivity and Biomedical Research by : Robert P. Marini

Download or read book The Common Marmoset in Captivity and Biomedical Research written by Robert P. Marini and published by Academic Press. This book was released on 2018-11-19 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications Includes contributions from renowned and international authors and editors Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

The Prokaryotes

Author : Edward F. DeLong
Publisher : Springer
ISBN 13 : 9783642389214
Total Pages : 0 pages
Book Rating : 4.3/5 (892 download)

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Book Synopsis The Prokaryotes by : Edward F. DeLong

Download or read book The Prokaryotes written by Edward F. DeLong and published by Springer. This book was released on 2014-10-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Prokaryotes is a comprehensive, multi-authored, peer reviewed reference work on Bacteria and Achaea. This fourth edition of The Prokaryotes is organized to cover all taxonomic diversity, using the family level to delineate chapters. Different from other resources, this new Springer product includes not only taxonomy, but also prokaryotic biology and technology of taxa in a broad context. Technological aspects highlight the usefulness of prokaryotes in processes and products, including biocontrol agents and as genetics tools. The content of the expanded fourth edition is divided into two parts: Part 1 contains review chapters dealing with the most important general concepts in molecular, applied and general prokaryote biology; Part 2 describes the known properties of specific taxonomic groups. Two completely new sections have been added to Part 1: bacterial communities and human bacteriology. The bacterial communities section reflects the growing realization that studies on pure cultures of bacteria have led to an incomplete picture of the microbial world for two fundamental reasons: the vast majority of bacteria in soil, water and associated with biological tissues are currently not culturable, and that an understanding of microbial ecology requires knowledge on how different bacterial species interact with each other in their natural environment. The new section on human microbiology deals with bacteria associated with healthy humans and bacterial pathogenesis. Each of the major human diseases caused by bacteria is reviewed, from identifying the pathogens by classical clinical and non-culturing techniques to the biochemical mechanisms of the disease process. The 4th edition of The Prokaryotes is the most complete resource on the biology of prokaryotes. The following volumes are published consecutively within the 4th Edition: Prokaryotic Biology and Symbiotic Associations Prokaryotic Communities and Ecophysiology Prokaryotic Physiology and Biochemistry Applied Bacteriology and Biotechnology Human Microbiology Actinobacteria Firmicutes Alphaproteobacteria and Betaproteobacteria Gammaproteobacteria Deltaproteobacteria and Epsilonproteobacteria Other Major Lineages of Bacteria and the Archaea

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309211093
Total Pages : 560 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases by : Institute of Medicine

Download or read book Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.

Global Health Impacts of Vector-Borne Diseases

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309377595
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Global Health Impacts of Vector-Borne Diseases by : National Academies of Sciences, Engineering, and Medicine

Download or read book Global Health Impacts of Vector-Borne Diseases written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-21 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Bad Bug Book

Author : Mark Walderhaug
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781495203619
Total Pages : 292 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis Bad Bug Book by : Mark Walderhaug

Download or read book Bad Bug Book written by Mark Walderhaug and published by Createspace Independent Publishing Platform. This book was released on 2014-01-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.

The Emergence of Zoonotic Diseases

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309169739
Total Pages : 176 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Emergence of Zoonotic Diseases by : Institute of Medicine

Download or read book The Emergence of Zoonotic Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2002-04-09 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zoonotic diseases represent one of the leading causes of illness and death from infectious disease. Defined by the World Health Organization, zoonoses are "those diseases and infections that are naturally transmitted between vertebrate animals and man with or without an arthropod intermediate." Worldwide, zoonotic diseases have a negative impact on commerce, travel, and economies. In most developing countries, zoonotic diseases are among those diseases that contribute significantly to an already overly burdened public health system. In industrialized nations, zoonotic diseases are of particular concern for at-risk groups such as the elderly, children, childbearing women, and immunocompromised individuals. The Emergence of Zoonotic Diseases: Understanding the Impact on Animal and Human Health, covers a range of topics, which include: an evaluation of the relative importance of zoonotic diseases against the overall backdrop of emerging infections; research findings related to the current state of our understanding of zoonotic diseases; surveillance and response strategies to detect, prevent, and mitigate the impact of zoonotic diseases on human health; and information about ongoing programs and actions being taken to identify the most important needs in this vital area.

Microbial Threats to Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309185548
Total Pages : 397 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Threats to Health by : Institute of Medicine

Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Global Public Health

Author : Franklin White
Publisher : Oxford University Press
ISBN 13 : 0199751900
Total Pages : 378 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Global Public Health by : Franklin White

Download or read book Global Public Health written by Franklin White and published by Oxford University Press. This book was released on 2013-03-14 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amid ongoing shifts world economic and political systems, the promise for future public health is more tenuous than ever. Will the today's economic systems sustain tomorrow's health? Will future generations inherit fair access to health and health care? The best hope for the health of future generations is the establishment of a well-grounded, global public health system for today. To that end, Global Public Health: Ecological Foundations addresses both the challenges and cooperative solutions of contemporary public health, all within a framework of social justice, environmental sustainability, and global cooperation. With an emphasis upon ecological foundations, this text approaches public health principles-history, foundations, topics, and applications-with a community-first perspective. By achieving global reach through cooperative, local interventions, this text illustrates that through the practice of public health we can also maintain the health of our world. Blending established wisdom with new perspectives, Global Public Health will stimulate better understanding of how the different streams of public health can work more synergistically to promote global health equity. It is a foundation on which future public health measures can be built and succeed.

Occupational Health and Safety in the Care and Use of Nonhuman Primates

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309167949
Total Pages : 180 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Occupational Health and Safety in the Care and Use of Nonhuman Primates by : National Research Council

Download or read book Occupational Health and Safety in the Care and Use of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 2003-06-13 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

Elsevier's Integrated Review Immunology and Microbiology E-Book

Author : Jeffrey K. Actor
Publisher : Elsevier Health Sciences
ISBN 13 : 1455727016
Total Pages : 207 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Elsevier's Integrated Review Immunology and Microbiology E-Book by : Jeffrey K. Actor

Download or read book Elsevier's Integrated Review Immunology and Microbiology E-Book written by Jeffrey K. Actor and published by Elsevier Health Sciences. This book was released on 2011-09-28 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effectively merge basic science and clinical skills with Elsevier’s Integrated Review of Immunology and Microbiology, by Jeffrey K. Actor, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in immunology and microbiology while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. . This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with case-based and USMLE-style questions that provide effective chapter review and quick practice for your exams. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Grasp and retain vital concepts more easily thanks to a color-coded format, succinct text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material.

Vector-Borne Diseases

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309177707
Total Pages : 350 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Vector-Borne Diseases by : Institute of Medicine

Download or read book Vector-Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2008-03-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever, and plague, cause a significant fraction of the global infectious disease burden; indeed, nearly half of the world's population is infected with at least one type of vector-borne pathogen (CIESIN, 2007; WHO, 2004a). Vector-borne plant and animal diseases, including several newly recognized pathogens, reduce agricultural productivity and disrupt ecosystems throughout the world. These diseases profoundly restrict socioeconomic status and development in countries with the highest rates of infection, many of which are located in the tropics and subtropics. Although this workshop summary provides an account of the individual presentations, it also reflects an important aspect of the Forum philosophy. The workshop functions as a dialogue among representatives from different sectors and allows them to present their beliefs about which areas may merit further attention. These proceedings summarize only the statements of participants in the workshop and are not intended to be an exhaustive exploration of the subject matter or a representation of consensus evaluation. Vector-Borne Diseases : Understanding the Environmental, Human Health, and Ecological Connections, Workshop Summary (Forum on Microbial Threats) summarizes this workshop.

Studies in Disease Ecology

Author : Jacques Meyer May
Publisher :
ISBN 13 :
Total Pages : 646 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Studies in Disease Ecology by : Jacques Meyer May

Download or read book Studies in Disease Ecology written by Jacques Meyer May and published by . This book was released on 1961 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioterrorism and Infectious Agents

Author : I.W. Fong
Publisher : Springer Science & Business Media
ISBN 13 : 1441912665
Total Pages : 284 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bioterrorism and Infectious Agents by : I.W. Fong

Download or read book Bioterrorism and Infectious Agents written by I.W. Fong and published by Springer Science & Business Media. This book was released on 2010-03-18 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiled by two leading experts in the field, this volume provides a concise, timely, and authoritative review of some of the most problematic infections of the new century. It presents issues and new ideas for preventing and controlling infectious diseases.

Encyclopedia of Infectious Diseases

Author : Michel Tibayrenc
Publisher : John Wiley & Sons
ISBN 13 : 0470114193
Total Pages : 807 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Encyclopedia of Infectious Diseases by : Michel Tibayrenc

Download or read book Encyclopedia of Infectious Diseases written by Michel Tibayrenc and published by John Wiley & Sons. This book was released on 2007-07-31 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, vector control, satellite detection, surveillance, modeling, and high-throughput technologies. The final part explores specialized topics of current concern, including bioterrorism, world market and infectious diseases, and antibiotics for public health. Each article is written by one or more leading experts in the field of infectious diseases. These experts place all the latest findings from various disciplines in context, helping readers understand what is currently known, what the next generation of breakthroughs is likely to be, and where more research is needed. Several features facilitate research and deepen readers' understanding of infectious diseases: Illustrations help readers understand the pathogenesis and diagnosis of infectious diseases Lists of Web resources serve as a gateway to important research centers, government agencies, and other sources of information from around the world Information boxes highlight basic principles and specialized terminology International contributions offer perspectives on how infectious diseases are viewed by different cultures A special chapter discusses the representation of infectious diseases in art With its multidisciplinary approach, this encyclopedia helps point researchers in new promising directions and helps health professionals better understand the nature and treatment of infectious diseases.