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Transplantation Of The Endocrine Pancreas In Diabetes Mellitus
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Book Synopsis Transplantation of the Endocrine Pancreas in Diabetes Mellitus by : Reinout van Schilfgaarde
Download or read book Transplantation of the Endocrine Pancreas in Diabetes Mellitus written by Reinout van Schilfgaarde and published by Elsevier Publishing Company. This book was released on 1988 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas by : Giuseppe Orlando
Download or read book Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas written by Giuseppe Orlando and published by Academic Press. This book was released on 2019-11-09 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes
Book Synopsis Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas by : Giuseppe Orlando
Download or read book Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas written by Giuseppe Orlando and published by Academic Press. This book was released on 2019-11-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes
Book Synopsis The Endocrine Pancreas by : Ellis Samols
Download or read book The Endocrine Pancreas written by Ellis Samols and published by Lippincott Williams & Wilkins. This book was released on 1991 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Pathology of the Endocrine Pancreas in Diabetes by : Pierre J. Lefebvre
Download or read book The Pathology of the Endocrine Pancreas in Diabetes written by Pierre J. Lefebvre and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus represents one of the most frequent and serious clinical syn dromes in contemporary medicine. Since the end of the nineteenth century, the endocrine pancreas has been implicated in the pathogenesis of this disease. Several pathologists of the twentieth century detected various lesions and mor phologic alterations in the pancreatic islets of diabetic patients, but the patho physiologic basis of their findings remained long obscure. The systematic mi croscopic work of WILLY GEPTS clarified the views and related the variety in histopathology to differences in origin, duration and clinical expression of the disease. Over the past two decades, the concept of a multifactorial origin of diabetes has become widely accepted. Various agents and mechanisms have been identified which can lead to a quantitative or qualitative deficit in pancre atic B-cells. The purpose of this book is to bring an update on the many path ways which may induce an absolute or relative insufficiency in insulin release and hence a diabetic state. Rather than bringing a complete account on all re search relevant to the understanding of the pathology of the diabetic pancreas, the authors of the various chapters of this volume have focussed on selected processes which can impair B-cell function, survival or regeneration.
Book Synopsis The Endocrine Pancreas and Juvenile Diabetes by : David M. Klachko
Download or read book The Endocrine Pancreas and Juvenile Diabetes written by David M. Klachko and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Robert L. Jackson, Professor of Child Health at the Uni versity of Missouri-Columbia, decided to retire from clinical practice in 1977 and the Department of Child Health planned a con ference in his honor. The Thirteenth Annual MidweSt Conference on Endocrinology and Metabolism also was in the planning stages and scheduled for two days in the fall. It seemed appropriate to com bine the two into an expanded three-day conference. In view of Dr. Jackson's international reputation in the study and care of children with diabetes mellitus, the conference topic was not dif ficult to find. Experts in this field were delighted to be asked to speak at a conference in Dr. Jackson's honor. We selected a number of excellent speakers to survey the physiology and pathophy siology of pancreatic hormones and their effects in diabetes mel litus, to discuss current knowledge of the microvascular complica tions of the disease, and to put it all into the proper historical perspective of where we have been and where we are going. We think the conference achieved its objective to pay meaningful trib ute to a distinguished member of the scientific community. As with any conference, the conversion of the presentations and discussions to the printed page is a long and arduous process. Many manuscripts were completed well after the conference and references often are more recent than the date of the conference.
Book Synopsis Pancreas, Islet and Stem Cell Transplantation for Diabetes by : Nadey S. Hakim
Download or read book Pancreas, Islet and Stem Cell Transplantation for Diabetes written by Nadey S. Hakim and published by Oxford University Press, USA. This book was released on 2010-08-26 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and pancreatic stem cell transplantation, reflecting recent advances in the field, including the growing interest in stem cell research applicable to this condition.
Author :Rainer W.G. Gruessner Publisher :Springer Science & Business Media ISBN 13 :9780387005898 Total Pages :736 pages Book Rating :4.0/5 (58 download)
Book Synopsis Transplantation of the Pancreas by : Rainer W.G. Gruessner
Download or read book Transplantation of the Pancreas written by Rainer W.G. Gruessner and published by Springer Science & Business Media. This book was released on 2004-04-27 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although pancreas transplants have been performed for more than 30 years, the last few years have witnessed significant growth in the options available for pancreas transplantation as well as subtantial improvements in outcome. It is therefore appropriate that a new text summarize the recent advances and put forth the standard of future care. Transplantation of the Pancreas, edited by Drs. Gruessner and Sutherland fulfills this mission by providing a state-of-the-art, definitive reference work on pancreas transplantation for transplant surgeons and physicians as well as for endocrinologists, diabetologists, nephrologists, and neurologist. The editors, from the renowned University of Minnesota Transplant Division and the Diabetes Institute, have assembled a group of renowned experts to provide an all inclusive overview of pancreas transplantation. The text features insights on the pathophysiology of diabetes mellitus and the limitations of nontransplant treatments, highlights experimental research and clinical history of pancreas transplantation, and compares and contrasts different surgical procedures. The discussions detail the broad spectrum of posttransplant complications and their treatments, which frequently require skills in general, vascular, and laparoscopic surgery, interventional radiology, critical care, and infectious disease. Chapters on immunosuppression, immunology, pathology, long-term outcome, quality of life, and cost-effectiveness focus on issues unique to pancreas recipients. Evolving areas, such as pretransplant evaluation of pancreas transplant candidates, living donation, and the current status of islet transplantation are discussed. Augmented by more than 280 illustrations, including full color line drawings created exclusively for the text, this book is the standard reference for all transplant professionals as well as all physicians caring for diabetic patients.
Book Synopsis Pancreatic Islet Cell Transplantation by : Camillo Ricordi
Download or read book Pancreatic Islet Cell Transplantation written by Camillo Ricordi and published by Landes Bioscience. This book was released on 1992 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for researchers and clinicians who work with cell transplantation, this text discusses the latest methods and gives an overall update of the major fields of islet transplantation. Included are reports of recent clinical trials on successful islet transplantation in humans.
Book Synopsis Fetal Islet Transplantation by : Charles M. Peterson
Download or read book Fetal Islet Transplantation written by Charles M. Peterson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The breadth of research efforts represented by the many excellent papers in these proceedings is an eloquent testimonial to the idea of one man Dr. Josiah Brown-to whose memory this volume is dedicated. His tragic and unexpected loss in a swimming accident in August 1985 brought to an abrupt close a long and distinguished career as a physician and scientist. The possibility of using fetal pancreas tissue for transplantation into insulin-deficient diabetic recipients had intrigued Dr. Brown for several years prior to 1972, when he began in earnest to assemble a research team to explore this idea in detail. He felt that improvements in the formulation and administration of insulin (even the later recombinant human insulin) had taken us about as far as we could go in treating diabetes, and that methods for achieving complete cures must be explored. Numerous advantages of the fetal pancreas quickly became apparent, and were explored scientifically by Dr. Brown and his group. Transplanted pancreas tissue from a fetal donor of the appropriate developmental stage engrafts quickly, and can reverse diabetes very efficiently (1-3). By shunting the venous'drainage of the graft into the hepatic portal vein, a single pancreatic rudiment can, in time, provide enough insulin to restore normoglycemia and urine volume in a diabetic adult recipient (4). As with fetal pancreas rudiments in culture, transplanted fetal pancreas tissue loses its exocrine character, while continuing to develop and maintain endocrine function.
Book Synopsis Pancreas and Islet Transplantation by : Nadey S. Hakim
Download or read book Pancreas and Islet Transplantation written by Nadey S. Hakim and published by . This book was released on 2002 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes Mellitus is the principle cause of kidney failure and blindness in adults and leads to more cases of amputation and impotence than any other disease. It is one of the most common chronic diseases in childhood. The aims of pancreas or islet transplantation are to improve the quality of life of patients with insulin dependent diabetes mellitus and to ameliorate secondary complications. This book provides a comprehensive and international review of the recent advances in pancreas and islet transplantation. It covers surgical techniques, issues surrounding organ preservation, immunosuppression and the control of other complications, all of which contribute to the potential for such transplantations to evolve as the treatment of choice for insulin dependent diabetes. The editors have compiled a strong and international team of contribution authors. This book is essential reading for transplant surgeons and all those involved in researching or treating diabetes mellitus.
Book Synopsis Molecular Basis of Pancreas Development and Function by : Joel F. Habener
Download or read book Molecular Basis of Pancreas Development and Function written by Joel F. Habener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is rapidly increasing in prevalence throughout both developed and developing countries. The social and economic burden of this disease is estimated to cost 14 billion dollars worldwide. In the USA alone, 15 million individuals are diabetic, nearly half of them unaware of their condition. Complications of diabetes mellitus are the leading causes for blindness, limb amputation and chronic renal failure and kidney transplantation in industrialized countries. Further, diabetes mellitus per se and the metabolic derangement associated with diabetes are important risk factors for cardiovascular disease. Diabetes, as defined by an elevated fasting blood glucose level is presently subdivided in etiologically distinct groups. The most prevalent being type 2 (adult onset) diabetes characterized by insulin resistance and failure of the ~-cell to supply insulin in amounts sufficient to meet the body's needs. Type 1 (juvenile) diabetes, most commonly with an onset during childhood and adolescence, is caused by an auto-immune destruction of the pancreatic ~-cells. The causations of both type 1 and type 2 diabetes involve a combination of complex genetic traits and environmental influences. A third category are the mature onset diabetes of the young (MODY). This comparatively small group of patients (-10% of diabetes) presents relative early in life «30 years of age) compared to the more common late onset type 2 diabetes.
Author :Luis H. Toledo-Pereyra Publisher :Springer Science & Business Media ISBN 13 :1461317355 Total Pages :301 pages Book Rating :4.4/5 (613 download)
Book Synopsis Pancreas Transplantation by : Luis H. Toledo-Pereyra
Download or read book Pancreas Transplantation written by Luis H. Toledo-Pereyra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December, 1966, two patients dying of months after the transplants had been per uremia as a result of diabetic kidney disease formed. This was long enough, however, to were offered a small chance of survival. Ac establish unequivocally in both patients cording to the thinking of the time, it was that an endocrine organ, the pancreas, could inappropriate-and perhaps even unethical function normally and for many days as a to offer them either chronic hemodialysis or human-to-human graft. The patients had kidney transplantation. These were considered become normoglycemic independent of insulin a waste of effort because it was believed that injections. scarce medical resources should not be spent The possible long-term benefits of restoring on patients, uremic or not, whose chances of insulin function were hotly argued then, and surviving for more than a few months were they have not been fully determined 20 years thought to be very small. Reduced to its later. It seems to me now, however, that the essence, the idea was that diabetic patients basic premise is sounder than I realized in were terrible risks and would remain so even if 1966: if one could restore an effective, norm the uremia were corrected.
Book Synopsis Diabetes Secondary to Endocrine and Pancreatic Disorders by : E. Ghigo
Download or read book Diabetes Secondary to Endocrine and Pancreatic Disorders written by E. Ghigo and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-10 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1997 classification of diabetes mellitus, now accepted worldwide, includes a large section of ‘Other specific types of diabetes’, a good part of which is made up of diabetes secondary to other endocrine or pancreatic disorders. However, a comprehensive overview on how these disorders may lead to diabetes, and how to diagnose and treat them, was not available so far. Filling this gap, this book includes detailed descriptions of glucose metabolism derangements in other endocrine and pancreatic disorders. Leading experts in their fields present an exhaustive overview of the most-updated evidence on the etiopathological mechanisms underlying the development of diabetes in patients with endocrine and pancreatic disorders, and the relevant diagnostic and therapeutic approaches. Because of its multidisciplinary approach, this book is of great interest to endocrinologists, diabetologists, general practitioners, internal medicine specialists and surgeons, and will remain a reference source for years to come.
Book Synopsis The Diabetic Pancreas by : Bruno Volk
Download or read book The Diabetic Pancreas written by Bruno Volk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 951 pages. Available in PDF, EPUB and Kindle. Book excerpt: I consider it an honor to have been asked to write the Foreword for The Diabetic Pancreas. Although I have been involved in the study of the pancreas since 1921, my interest goes back even further to the time, in 1918, that my father's sister, a nurse who had trained at the Massachusetts General Hospit.al, devel oped diabetes, lost weight, and died in diabetic coma. This sad event made a deep impression on me and was certainly pardy responsible for my choosing to join the Department of Physiology of the University of Toronto to begin a career in research into diabetes. This is not the place to describe in detail the wide-ranging research and study of the diabetic pancreas in which I have engaged in the past 56 years. Suffice it to say that I am familiar enough with the subject area to be able to predict a great future for this book. The editors have undertaken a very ambitious and worthwhile project, and their efforts have been supported and strengthened by contributors who are respected authorities in their fields, thus ensuring a successful presentation of this major work.
Book Synopsis Quick Guide to Kidney Transplantation by : Phuong-Chi T Pham
Download or read book Quick Guide to Kidney Transplantation written by Phuong-Chi T Pham and published by Lippincott Williams & Wilkins. This book was released on 2019-02-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise, easy to read, and designed for quick reference,Quick Guide to Kidney Transplantationis a compact resource for general nephrologists, residents, fellows, nurse practitioners, and others involved in the care of post-transplant patients. Focusing on must-know clinical information needed to provide optimal patient care, this expertly written guide helps you gain the knowledge and expertise you need in this complex area.
Book Synopsis Pancreatic Islet Isolation by : Miriam Ramírez-Domínguez
Download or read book Pancreatic Islet Isolation written by Miriam Ramírez-Domínguez and published by Springer. This book was released on 2016-09-01 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
