Translational Systems Medicine and Oral Disease

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Publisher : Academic Press
ISBN 13 : 0128137630
Total Pages : 458 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Translational Systems Medicine and Oral Disease by : Stephen Sonis

Download or read book Translational Systems Medicine and Oral Disease written by Stephen Sonis and published by Academic Press. This book was released on 2019-09-14 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Oral Mucosal Immunity and Microbiome

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Publisher : Springer Nature
ISBN 13 : 3030285243
Total Pages : 192 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Oral Mucosal Immunity and Microbiome by : Georgios N. Belibasakis

Download or read book Oral Mucosal Immunity and Microbiome written by Georgios N. Belibasakis and published by Springer Nature. This book was released on 2019-11-15 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.

Translational Regenerative Medicine

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Publisher : Academic Press
ISBN 13 : 0124104576
Total Pages : 607 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Translational Regenerative Medicine by : Anthony Atala

Download or read book Translational Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2014-12-01 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Practical Data Analytics for Innovation in Medicine

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Publisher : Academic Press
ISBN 13 : 0323952755
Total Pages : 578 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Practical Data Analytics for Innovation in Medicine by : Gary D. Miner

Download or read book Practical Data Analytics for Innovation in Medicine written by Gary D. Miner and published by Academic Press. This book was released on 2023-02-08 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics. Brings a historical perspective in medical care to discuss both the current status of health care delivery worldwide and the importance of using modern predictive analytics to help solve the health care crisis Provides online tutorials on several predictive analytics systems to help readers apply their knowledge on today’s medical issues and basic research Teaches how to develop effective predictive analytic research and to create decisioning/prescriptive analytic systems to make medical decisions quicker and more accurate

Systems Biology, Bioinformatics and Livestock Science

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Publisher : Bentham Science Publishers
ISBN 13 : 9815165623
Total Pages : 335 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Systems Biology, Bioinformatics and Livestock Science by : Anupam Nath Jha

Download or read book Systems Biology, Bioinformatics and Livestock Science written by Anupam Nath Jha and published by Bentham Science Publishers. This book was released on 2023-11-08 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the intricate world of livestock sciences and production through the lens of systems biology. Offering a comprehensive exploration of both fundamental and advanced aspects, it unearths the potential of systems biology in the realm of livestock. The book presents 13 edited chapters on cutting-edge knowledge about systems biology and omics technology, showcasing genomics, transcriptomics, proteomics, metabolomics, and more. It illuminates the role of systems biology in livestock and disease management. Readers will learn about power of technologies that merge computational biology, nanobiotechnology, artificial intelligence, and single-cell sequencing. Each chapter is written by scientific experts and includes references for further reading. The book covers 4 key themes: Introduction to Systems Biology in Livestock Science: Uncover the foundation of integrating systems biology with omics data for animal scientists. Multi-scale Modeling Techniques: Explore how multi-scale modeling is shaping the future of system biology. Livestock Viral Diseases: Gain insights into how systems biology is revolutionizing our understanding of livestock viral diseases. Single Cell RNA-Sequencing: Understand the potential of this advanced technique in studying livestock animals at a cellular level. This book is a timely resource for students and researchers, offering a pathway to comprehend the crucial role systems biology plays in sustainable livestock production and management.

How Synthetic Drugs Work

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Publisher : Academic Press
ISBN 13 : 0323913687
Total Pages : 601 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis How Synthetic Drugs Work by : Imran Kazmi

Download or read book How Synthetic Drugs Work written by Imran Kazmi and published by Academic Press. This book was released on 2022-09-06 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs. Presents the mechanism of action of most recent synthetic drugs available Includes newly reported action mechanisms of conventional drugs Contains colored illustrations of the pathway through which the drug exerts therapeutic action

Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

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Publisher : Springer Nature
ISBN 13 : 9811654220
Total Pages : 4078 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Handbook of Oxidative Stress in Cancer: Therapeutic Aspects by : Sajal Chakraborti

Download or read book Handbook of Oxidative Stress in Cancer: Therapeutic Aspects written by Sajal Chakraborti and published by Springer Nature. This book was released on 2022-09-28 with total page 4078 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. ​

Oral Health and Herbal Medicine

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Publisher : Springer
ISBN 13 : 3030043363
Total Pages : 46 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Oral Health and Herbal Medicine by : Khalid Rehman Hakeem

Download or read book Oral Health and Herbal Medicine written by Khalid Rehman Hakeem and published by Springer. This book was released on 2018-12-17 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral health loss is one of the major problems existing all over the world and is one of the top causes of death when unmanaged. The oral cavity is home to numerous pathogenic microorganisms, some of which are responsible for the progression and development of various systemic diseases such as cancer, diabetes and myocardial infarction. Worldwide, 60–90% of school children and nearly 100% of adults have dental cavities, often leading to pain and discomfort. There are implications for the global economy as well, due to the continuous burden of investing resources to maintain oral hygiene. Not surprisingly, developing countries are disproportionally affected. There is thus an urgent need to develop economical solutions for the treatment of oral diseases. The trend of exploring plants or plant-derived compounds for the prevention and cure of death-causing diseases is on the rise. The use of traditional medicine for oral diseases is an ancient practice in which medicinal herbs play a major role. Medicinal plants have minimal side effects and no denigrating properties. Accordingly the use of medicinal plants to curtail oral pathogens has been reported by a number of studies. The present book updates the issues related to oral health, oral diseases and the role of medicinal plants in overcoming orally-derived health problems. We also highlight the knowledge gaps in oral health related problems with medicinal plants as one of the solutions. Our ultimate goal is to encourage future research and application of medicinal plants for economical and efficient treatment of oral diseases.

An Introduction To Biomaterials Science And Engineering

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Publisher : World Scientific
ISBN 13 : 9811228191
Total Pages : 413 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis An Introduction To Biomaterials Science And Engineering by : A Sandeep Kranthi Kiran

Download or read book An Introduction To Biomaterials Science And Engineering written by A Sandeep Kranthi Kiran and published by World Scientific. This book was released on 2021-04-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a broad scope of the field of biomaterials science and technology, focusing on theory, advances and applications. It is written for those who would like to develop their interest and knowledge towards biomaterials or materials science and engineering. All aspects of biomaterials science are thoroughly addressed, from basic principles of biomaterials, organs and medical devices to advanced topics such as tissue engineering, surface engineering, sterilization techniques, 3D printing and drug delivery systems. Readers are also introduced to major concepts of surface modification techniques, and potential applications of different classes of biomaterials. Multiple-choice questions at the end of every chapter will be helpful for students to test their understanding of each topic, with answers provided at the end of the book.Ultimately, this book offers a one-stop source of information on the essentials of biomaterials and engineering. It is useful both as an introduction and advanced reference on recent advances in the biomaterials field. Suitable readers include undergraduate and graduate students, especially those in Materials Science, Biomedical Engineering and Bioengineering.

ICT for Health Science Research

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Publisher : IOS Press
ISBN 13 : 1614999597
Total Pages : 294 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis ICT for Health Science Research by : A. Shabo (Shvo)

Download or read book ICT for Health Science Research written by A. Shabo (Shvo) and published by IOS Press. This book was released on 2019-04-17 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information and Communications Technology (ICT) is used in healthcare and health science research in application domains such as clinical trials and the development of drug and medical devices, as well as in translational medicine, with the aim of improving prevention, diagnosis, and interventions in health and care. This book presents accepted papers from the 2019 European Federation of Medical Informatics conference (EFMI STC 2019), held in Hanover, Germany, from 7 – 10 April 2019. More than 90 submissions were received, from which, after review, the Scientific Program Committee (SPC) accepted 50 full papers to be included in this volume of proceedings. In addition, 16 poster presentations were accepted. This year, ICT for Health Science Research was selected as the focus topic, and the conference also honors Prof. Peter Leo Reichertz (1930 – 1987), one of the founding fathers of ICT healthcare and an originator of the term Medical Informatics. The conference focuses on recent research & development supporting information systems in biomedical, translational and clinical research, as well as semantic interoperability across such systems for the purpose of data sharing and the analytics of cross-system integrated data. Papers are divided into 12 categories covering topics including digitization; data privacy; interoperability; data-driven decision support; mobile data capture; and ICT for clinical trials. The book will be of interest to all healthcare researchers and practitioners whose work involves the use of ICT.

Skin Cancer: Pathogenesis and Diagnosis

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Publisher : Springer Nature
ISBN 13 : 9811603642
Total Pages : 251 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Skin Cancer: Pathogenesis and Diagnosis by : Ashish Dwivedi

Download or read book Skin Cancer: Pathogenesis and Diagnosis written by Ashish Dwivedi and published by Springer Nature. This book was released on 2021-08-02 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer. It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.

Integration of Medical and Dental Care and Patient Data

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Publisher : Springer Science & Business Media
ISBN 13 : 1447121848
Total Pages : 449 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Integration of Medical and Dental Care and Patient Data by : Valerie Powell

Download or read book Integration of Medical and Dental Care and Patient Data written by Valerie Powell and published by Springer Science & Business Media. This book was released on 2012-01-18 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book informs readers of the needs and rationale for the integration of medical and dental care and information with an international perspective as to how and where medical and dental care separated into specific domains. It provide high level guidance on issues involved with care and data integration and how to achieve an integrated model of health care supported by integrated HIT. A patient typically expects that a visit to a dentist can usually be resolved immediately. This expectation places a premium on instant, accurate, thorough, and current information. The state-of-the-art of fully integrated (dental-medical) electronic health record (EHR) is covered and this is contrasted with the current state of dental-medical software. While dentists in the US Veterans Health Administration (VHA), the US Indian Health Service (IHS), or the US military, for example, have access to fully integrated health records, most US clinicians still gather information from separate sources via fax or phone calls. The authors provide an in-depth discussion of the role of informatics and information science in the articulation of medical and dental practices and clinical data with the focus on applied clinical informatics to improve quality of care, practice efficiency, coordination and continuity of care, communication between physicians and dentists and to provide a more comprehensive care for the patients. Lastly, the book examines advances in medical and dental research and how these may affect dentistry in the future. Most new advances in healthcare research are information-intensive.

Proceedings of 6th Euro-Global Conference on Infectious Diseases 2017

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Author :
Publisher : ConferenceSeries
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4./5 ( download)

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Book Synopsis Proceedings of 6th Euro-Global Conference on Infectious Diseases 2017 by : ConferenceSeries

Download or read book Proceedings of 6th Euro-Global Conference on Infectious Diseases 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: September 07-09, 2017 Paris, France Key Topics : Viral Infectious Diseases, Bacterial Infectious Diseases, Ebola Outbreak and Approaches for Prevention, Fungal Infectious Diseases, New Antiviral, Antibacterial and Antifungal Agents, Market Trends Of Infectious Diseases, Parasitic Diseases, Bacterial Susceptibility & Resistance, Nosocomial Infections, Detection and preventing infections in healthcare, Public health practice, Vaccines, Respiratory Diseases, Infectious Agents and the Human Immune Response, Infectious Diseases: Worms, Prions, and Fungi, Protozoal Diseases, Clinical Infectious Disease, Infectious Disease Epidemiology, Emerging Infectious Diseases, Laboratory Diagnosis of Infectious Diseases, Infectious Diseases of Humans, Infectious Diseases and Pathology, Microbiology and Infectious Diseases, Infectious Diseases of Livestock, Infectious Diseases of the Female Genital Tract, Molecular Diagnostics of Infectious Diseases, Pediatric Infectious Diseases, Bacterial Genomes and Infectious Diseases:, Drug Interactions in Infectious Diseases, Infectious Diseases in Children, Medical Pioneers in Infectious Diseases, Infectious Diseases and Tropical Medicine, Infectious Diseases in Critical Care Medicine, Infectious Diseases and Arthropods, Preventing Infectious Diseases, Feline Infectious Diseases, Tropical Infectious Diseases, Infectious Diseases in America, Infectious Diseases in Europe, Infectious Diseases in UK, Infectious Diseases in Asia, Infectious Diseases in Africa, Sexually transmitted Diseases and infection,

Salt Fluoridation

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Salt Fluoridation by :

Download or read book Salt Fluoridation written by and published by World Health Organization. This book was released on 1986 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This publication discusses salt flouridation as a means of preventing dental caries. The state of dental health in the Americas is reviewed and the results of two conferences on salt flouridation are examined. Topics include: salt flouridation in various countries; epidemiologic nutritional, and metabolic aspects of salt flouridation; sociopolitical, economic, and educational aspects of salt flouridation; and monitoring, supervision, and safety of salt flouridation.

Proceedings of 3rd International Conference and Expo on Ceramics and Composite Materials 2017

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Author :
Publisher : ConferenceSeries
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4./5 ( download)

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Book Synopsis Proceedings of 3rd International Conference and Expo on Ceramics and Composite Materials 2017 by : ConferenceSeries

Download or read book Proceedings of 3rd International Conference and Expo on Ceramics and Composite Materials 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 26-27, 2017 Madrid, Spain Key Topics : Ceramics and Glasses, Advanced Ceramic Materials, Ceramics and Composites, Composite Ceramic Materials, Ceramic Coatings, Advanced Materials and Technologies, Materials and Innovative Processing Ideas, Nanostructured Ceramics, Porous Ceramics, Sintering, Crystalline Materials, Ceramics Applications, Bioceramics and Medical Applications, Functional Ceramics and Inorganics, Ultra-High Temperature Ceramics, Entrepreneurs Investment Meet, Ceramic Compounds: Ceramic Materials, Ceramics in Biology and Medicine, Ceramic Industry and Environment, Non-oxide Ceramics, Nuclear Ceramics, Sols, Gels and Organic Chemistry,

Computational Immunology

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Publisher : CRC Press
ISBN 13 : 1351023489
Total Pages : 181 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Computational Immunology by : Shyamasree Ghosh

Download or read book Computational Immunology written by Shyamasree Ghosh and published by CRC Press. This book was released on 2020-01-31 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Systems Medicine

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Publisher : Academic Press
ISBN 13 : 0128160780
Total Pages : 1571 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Systems Medicine by :

Download or read book Systems Medicine written by and published by Academic Press. This book was released on 2020-08-24 with total page 1571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information