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Translational Approach To Heart Failure
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Book Synopsis Translational Approach to Heart Failure by : Jozef Bartunek
Download or read book Translational Approach to Heart Failure written by Jozef Bartunek and published by Springer Science & Business Media. This book was released on 2013-07-13 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary “heart team” approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.
Book Synopsis Translational Research in Coronary Artery Disease by : Wilbert S. Aronow
Download or read book Translational Research in Coronary Artery Disease written by Wilbert S. Aronow and published by Academic Press. This book was released on 2015-10-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. - Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data - Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease - Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease
Download or read book Cardiac Arrhythmias written by Endre Zima and published by BoD – Books on Demand. This book was released on 2022-03-09 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac arrhythmias are common triggers of emergency admission to cardiology or high-dependency departments. Most cases are easy to diagnose and treat, while others may present a challenge to healthcare professionals. A translational approach to arrhythmias links molecular and cellular scientific research with clinical diagnostics and therapeutic methods, which may include both pharmacological and non-pharmacologic treatments. This book presents a comprehensive overview of specific cardiac arrhythmias and discusses translational approaches to their diagnosis and treatment.
Book Synopsis Translational Cardiology by : Cam Patterson
Download or read book Translational Cardiology written by Cam Patterson and published by Springer Science & Business Media. This book was released on 2012-07-04 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.
Book Synopsis Myocardial Preservation by : Dennis V. Cokkinos
Download or read book Myocardial Preservation written by Dennis V. Cokkinos and published by Springer. This book was released on 2019-01-28 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.
Book Synopsis Thyroid and Heart by : Giorgio Iervasi
Download or read book Thyroid and Heart written by Giorgio Iervasi and published by Springer Nature. This book was released on 2020-03-19 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.
Book Synopsis A Translational Genomics Approach to Dissect Mechanisms of Heart Failure and Recovery by : Francesco Pesce
Download or read book A Translational Genomics Approach to Dissect Mechanisms of Heart Failure and Recovery written by Francesco Pesce and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heart Failure by : Patrick M. McCarthy
Download or read book Heart Failure written by Patrick M. McCarthy and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing optimal care for heart failure patients is a complex challenge that requires cooperation and coordination across multiple disciplines. Now, you can apply the successful techniques pioneered at the Cleveland Clinic, which are carefully explored and explained in this text. Drs. McCarthy and Young draw on their experience to show how an interdisciplinary team works together to: arrive at a proper diagnosis initiate medical therapy make decisions regarding the best use of percutaneous therapies, surgical therapies, electrical therapies, and the use of mechanical circulatory support devices and transplantation. Throughout the book, they present the most updated evidence for both drug trials and surgical trials. They emphasize the benefits of performing the most complete surgery that is practical, then continuing medical therapy. Each chapter focuses on one aspect of treatment, but the authors recognize that the best way to manage an individual patient is often to adapt a variety of different therapies. They state their opinions clearly, identifying which part of care is science and which is art. Heart Failure: A Combined Medical and Surgical Approach is a true collaboration that helps you identify the most effective strategies – operative interventions, pacing and ICD treatment, new diagnostic tools, and pharmacotherapeutic developments – and implement them for your patients.
Book Synopsis The Failing Heart by : Naranjan S. Dhalla
Download or read book The Failing Heart written by Naranjan S. Dhalla and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Improving Outcomes in Heart Failure by : Debra K. Moser
Download or read book Improving Outcomes in Heart Failure written by Debra K. Moser and published by Jones & Bartlett Publishers. This book was released on 2001 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances have changed the way heart failure is treated and have resulted in substantial improvements in heart failure management. Improving Outcomes in Heart Failure addresses innovative ways of dealing with issues such as quality of life, treatment compliance, effective patient and family education and counseling, nonpharmacologic therapy, and new health care delivery models for improving the management of heart failure. With an interdisciplinary approach, this reference shows how heart failure outcomes and health care resource utilization can be improved significantly. Written by the editors of the distinguished Journal of Cardiovascular Nursing, Debra K. Moser, DNSc, RN and Barbara Riegel, DNSc, RN, CS, FAAN are well-known and nationally recognized experts in the field of cardiovascular nursing. Moser and Riegel have received numerous prestigious awards and honors and have contributed to many renowned journals on a wide variety of cardiovascular topics.
Book Synopsis Heart Failure and Diabetes: Metabolic Alterations and Therapeutic Interventions: a State-of-the-art Review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology by : Christoph Maack
Download or read book Heart Failure and Diabetes: Metabolic Alterations and Therapeutic Interventions: a State-of-the-art Review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology written by Christoph Maack and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heart Failure, An Issue of Medical Clinics by : Prakash C. Deedwania
Download or read book Heart Failure, An Issue of Medical Clinics written by Prakash C. Deedwania and published by Elsevier Health Sciences. This book was released on 2012-10-31 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important issue of Medical Clinics provides essential updates in heart failure. The following topics are covered: epidemiology, pathophysiology, and general approach for heart failure; symptoms, signs, diagnostic studies, and prognostic significance of systolic versus diastolic heart failure; the appropriate use of biomarkers; oral versus intravenous diuretic therapy; guideline-based therapy including RAAS blockade, beta-blockade, and aldosterone antagonist, appropriate use of AICD and biventricular pacing; role of ventricular assist device; pathophysiological consideration and management approaches in acute decompensated heart failure; pathophysiology and current approaches to cardiorenal syndrome; heart failure with other comorbidities including diabetes, obesity, anemia, and cancer; heart failure and atrial fibrillation; and the role of disease management strategies in heart failure.
Book Synopsis Aging and Heart Failure by : Bodh I. Jugdutt
Download or read book Aging and Heart Failure written by Bodh I. Jugdutt and published by Springer Science & Business Media. This book was released on 2014-02-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book synthesizes the major research advances in molecular, biochemical and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists and internists.
Book Synopsis Acute Heart Failure by : Alexandre Mebazaa
Download or read book Acute Heart Failure written by Alexandre Mebazaa and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
Book Synopsis Principles of Translational Science in Medicine by : Martin Wehling
Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions
Book Synopsis Oxidative Stress in Heart Diseases by : Sajal Chakraborti
Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2020-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Download or read book Thyroid and Heart written by and published by . This book was released on 2020 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies - including multicenter studies - have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects - kidney, hormonal pathways systems, brain, muscle, etc - of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists. .
