Transglutaminases

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805579012
Total Pages : 265 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Transglutaminases by : Kapil Mehta

Download or read book Transglutaminases written by Kapil Mehta and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: As newer members of the transglutaminase family are being discovered and new functions for existing members are being described, it becomes imperative to collect all the findings in a book. This volume provides the most comprehensive single source of information and will appeal to both new investigators just entering the field and established researchers aiming to elucidate the biological relevance of these enzymes in cancer, inflammation, autoimmune diseases and related areas of research.

Transglutaminases

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Author :
Publisher : Springer
ISBN 13 : 443155825X
Total Pages : 392 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Transglutaminases by : Kiyotaka Hitomi

Download or read book Transglutaminases written by Kiyotaka Hitomi and published by Springer. This book was released on 2016-02-04 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although several of their essential physiological roles have been revealed, many unknown and so far not fully understood functions have remained. In humans, there are eight active isozymes having distinct tissue and subcellular distribution patterns with different substrates and physiological roles. Accordingly, aberrant regulation of the enzyme reactions or expression may lead to or has been implicated in various pathologies including neurodegeneration, fibrosis, cancer, inflammation, celiac disease, and hemostasis disorders.To provide those who are new to the field with basic knowledge and recent information on transglutaminase structures and reactions, the mechanism by which transglutaminases modify substrate proteins and their contributions to multiple biological phenomena as well as disease phenotypes, the publication of the present transglutaminase book was planned, to consist of review articles by 17 expert investigators working in this exciting area of research. The book contains detailed information related to several transglutaminases from aspects in chemical and cellular biology, medical sciences, and biotechnology that will also supply starting points for drug discovery. Although many prominent findings have been published in recent years, this type of comprehensive review book has been missing in the scientific literature. This volume will be useful for investigators who either currently work on or will start addressing transglutaminase-related research, and beyond that, for a broad audience in the scientific community.

Transglutaminase

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Author :
Publisher : Elsevier
ISBN 13 : 0443191697
Total Pages : 384 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Transglutaminase by : Yi Zhang

Download or read book Transglutaminase written by Yi Zhang and published by Elsevier. This book was released on 2024-03-15 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases. Brings together basic knowledge and applied research on transglutaminase biology Considers a range of application areas, from biomedicine to drug development, tissue engineering, food processing, and materials synthesis Includes instructive protocols for basic and applied transglutaminase research Features chapter contributions from global leading experts in the field, across disciplines and applications

Transglutaminase

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461328292
Total Pages : 178 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Transglutaminase by : V.A. Najjar

Download or read book Transglutaminase written by V.A. Najjar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Neurochemistry and Molecular Neurobiology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387303464
Total Pages : 721 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Abel Lajtha

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2007-03-26 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Intermediate Filaments

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Publisher : Springer Science & Business Media
ISBN 13 : 3642702309
Total Pages : 276 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Intermediate Filaments by : P. Traub

Download or read book Intermediate Filaments written by P. Traub and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on cytoskeletal elements of eukaryotic cells has been expand ing explosively during the past 5 to 10 years. Due largely to the employment of electron and immunofluorescent microscopy, significant results have been obtained which have provided interesting new insights into the dynamics of nucleated cells at the structural, physiological, as well as developmental levels. While a substantial amount of knowledge has accumulated on the function of microfilaments and microtubules, the roles of the third major class of cytoskeletal structures in vertebrate cells, the intermediate filaments, have largely resisted clarification. The investigation of cultured cells and of tissues from various developmental stages has furnished a host of information on the inter-and intracellular distribution of the different types of intermediate filaments and led to the contention that they have a structural and organizing function in the cytoplasm of vertebrate cells. However, the results of recent experimen that vertebrate cells can function perfectly in the tation have shown complete absence of cytoplasmically extended intermediate filament meshworks. It is legitimate to suppose, therefore, that their function in vertebrate cells is much more subtle and complex than generally presumed. Our interest in the structure and function of intermediate filament proteins was initiated approximately 7 years ago while working on the regulation of macromolecular synthesis in picornavirus-infected mam malian cells. In attempts to demonstrate virus-induced changes in the nuclear protein components of the host cells, the nonionic detergent extraction method was used to purify nuclei.

Advances in Enzymology and Related Areas of Molecular Biology, Volume 78

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111810580X
Total Pages : 574 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Advances in Enzymology and Related Areas of Molecular Biology, Volume 78 by : Eric J. Toone

Download or read book Advances in Enzymology and Related Areas of Molecular Biology, Volume 78 written by Eric J. Toone and published by John Wiley & Sons. This book was released on 2011-10-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. Advances in Enzymology focuses on enzymes, the primary catalysts of life processes. The explanation of the behavior of enzymes can be found via studies of their chemical mechanisms and can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. The transglutaminases, first described in 1957, are a large, widely-distributed family of enzymes canonically responsible for the amidation/transamidation of protein side chains. The extraordinary diversity of names associated with various enzymatic activities now recognized and aggregated as transglutaminase bears witness to the remarkable diversity of biological roles associated with the activity, including myriad human diseases.

Advances in Post-Translational Modifications of Proteins and Aging

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Publisher : Springer Science & Business Media
ISBN 13 : 1468490427
Total Pages : 667 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Advances in Post-Translational Modifications of Proteins and Aging by : V. Zappia

Download or read book Advances in Post-Translational Modifications of Proteins and Aging written by V. Zappia and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 56 contributions presented at the 1st International Symposium on Post-Translational Modifications of Proteins and Ageing, held on the Island of Ischia (Naples, Italy) from May 11 to 15, 1987, under the auspices of the University of Naples and the Italian Society of Biochemistry. The primary aim of this interdisciplinary meeting was to promote a productive exchange among scientists from different cultural areas, and to give them the opportunity to discuss problems of common interest approached from different scientific standpoints. Although a large number of studies has led to a definition of the chemical mechanisms and of the main enzymological aspects of the several post-translational modifications of proteins, we are still far away from a complete elucidation of the functional significance of such processes. As a matter of fact, it seems reasonable that the presently available experi mental approaches and models employed to investigate the biological roles are still inadequate. The search for suitable model systems was a matter of discussion during the meeting, and will be a major challenge in the future. The most frequently employed approaches to this problem thus far have been in vitro, but several proteins reported to be excellent in vitro substrates failed to show any activity when assayed in in vivo models.

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

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Author :
Publisher : Woodhead Publishing
ISBN 13 : 008100852X
Total Pages : 392 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair by : Mario Barbosa

Download or read book Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair written by Mario Barbosa and published by Woodhead Publishing. This book was released on 2017-09-25 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Biological Adhesives

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Publisher : Springer
ISBN 13 : 331946082X
Total Pages : 380 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Biological Adhesives by : Andrew M. Smith

Download or read book Biological Adhesives written by Andrew M. Smith and published by Springer. This book was released on 2016-10-22 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals. As we learn more about their molecular and mechanical properties we begin to understand why they adhere so well and with this comes broad applications in areas such as medicine, dentistry, and biotechnology.

Glutamine and Glutamate Mammals

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Publisher : CRC Press
ISBN 13 : 1351080741
Total Pages : 280 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Glutamine and Glutamate Mammals by : Elling Kvamme

Download or read book Glutamine and Glutamate Mammals written by Elling Kvamme and published by CRC Press. This book was released on 2018-01-18 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the joint effort of a great many top scientists, this book covers most aspects of the metabolism and function of glutamine and glutamate in mammals.

The Biological Role of the Clot-stabilizing Enzymes: Transglutaminase and Factor XIII.

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Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Biological Role of the Clot-stabilizing Enzymes: Transglutaminase and Factor XIII. by : Koloman Laki

Download or read book The Biological Role of the Clot-stabilizing Enzymes: Transglutaminase and Factor XIII. written by Koloman Laki and published by . This book was released on 1972 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transglutaminases—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481645188
Total Pages : 17 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Transglutaminases—Advances in Research and Application: 2012 Edition by :

Download or read book Transglutaminases—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transglutaminases—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Transglutaminases in a compact format. The editors have built Transglutaminases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Transglutaminases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Transglutaminases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Comprehensive Biotechnology

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Publisher : Newnes
ISBN 13 : 0080885047
Total Pages : 5304 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Comprehensive Biotechnology by :

Download or read book Comprehensive Biotechnology written by and published by Newnes. This book was released on 2011-08-26 with total page 5304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Biotechnology, Six Volume Set continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field

The Differentiation Marker Transglutaminase and the Proto-oncogene Pim-1 in Human Keratinocytes in Culture

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Author :
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (56 download)

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Book Synopsis The Differentiation Marker Transglutaminase and the Proto-oncogene Pim-1 in Human Keratinocytes in Culture by : Barbara Ellen Stewart

Download or read book The Differentiation Marker Transglutaminase and the Proto-oncogene Pim-1 in Human Keratinocytes in Culture written by Barbara Ellen Stewart and published by . This book was released on 1995 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods to Determine Enzymatic Activity

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Publisher : Bentham Science Publishers
ISBN 13 : 1608053008
Total Pages : 334 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Methods to Determine Enzymatic Activity by : Alane Beatriz Vermelho

Download or read book Methods to Determine Enzymatic Activity written by Alane Beatriz Vermelho and published by Bentham Science Publishers. This book was released on 2013-11-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods to Determine Enzymatic Activity is a textbook about industrial enzymes. The book features definitions, classifications and applications of selected enzymes important in industry and in biotechnological processes. Analytical methods for these enzymes are also included in the text. The main objective of this textbook is to provide readers information focused on the current analysis methods of enzymatic activity at qualitative and quantitative levels. Each chapter is about one specific enzyme and contains information about its substrate and some biochemical properties. The methodologies are presented as an experimental protocol allowing interested readers to reproduce the experimental methods detailed within the textbook. These protocols contain the principle of the technique, materials, methods, and all steps necessary for the determination of enzyme activity and interpretation of results. Each methodology is illustrated with photos and schemes for a better and clear understanding. This book, therefore, uniquely brings modern analysis techniques of industrial enzymes in a single easy to understand volume. This textbook is suitable for undergraduate enzymology courses and advanced industrial biotechnology and microbiology courses.

Part I, Sar Studies in the Selective Inhibition of Tissue Transglutaminase 2 by Dihydroisoxazoles

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Author :
Publisher :
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Part I, Sar Studies in the Selective Inhibition of Tissue Transglutaminase 2 by Dihydroisoxazoles by : Richard Edward Watts

Download or read book Part I, Sar Studies in the Selective Inhibition of Tissue Transglutaminase 2 by Dihydroisoxazoles written by Richard Edward Watts and published by . This book was released on 2006 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: