Trajectories of Brain Abnormalities in Early Schizophrenia

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Publisher : Frontiers Media SA
ISBN 13 : 288971506X
Total Pages : 152 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Trajectories of Brain Abnormalities in Early Schizophrenia by : Antonio Vita

Download or read book Trajectories of Brain Abnormalities in Early Schizophrenia written by Antonio Vita and published by Frontiers Media SA. This book was released on 2021-10-20 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Neuropathology of Schizophrenia

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Publisher :
ISBN 13 :
Total Pages : 402 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis The Neuropathology of Schizophrenia by : Paul J. Harrison

Download or read book The Neuropathology of Schizophrenia written by Paul J. Harrison and published by . This book was released on 2000-08-24 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.

Examination of White Matter Integrity and Its Functional Impact in Early-onset Schizophrenia with Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging

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Publisher :
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.:/5 (757 download)

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Book Synopsis Examination of White Matter Integrity and Its Functional Impact in Early-onset Schizophrenia with Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging by : Marinos Kyriakopoulos

Download or read book Examination of White Matter Integrity and Its Functional Impact in Early-onset Schizophrenia with Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging written by Marinos Kyriakopoulos and published by . This book was released on 2010 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background -- Early-onset schizophrenia (EOS) offers a unique opportunity to better understand the developmental trajectory of brain abnormalities in the disorder. Longitudinal studies of early-onset cases support a back-to-front wave of gray matter volumetric deficits as patients move into adulthood. The timing of white matter abnormalities and the impact of structural changes in the normal integration of cerebral function in EOS remain unclear. -- Methods -- I used diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI) to investigate the effect of early-onset schizophrenia on white matter tract integrity and on the neural correlates of working memory. Nineteen adolescents with EOS and 20 healthy matched comparison subjects were clinically evaluated and examined with DTI and fMRI using the N-back verbal working memory task. White matter integrity in adolescent subjects (17 with schizophrenia and 17 healthy subjects) was also studied in comparison to adult subjects (17 with adult-onset schizophrenia and 17 healthy subjects) using DTI. All data were analysed using established non-parametric methods. -- Results -- Subjects with EOS showed microstructural white matter abnormalities in parietal regions and the left cerebellum. The adult-onset schizophrenia patients had more widespread white matter abnormalities while a differential effect of age at onset was noted bilaterally in the medial frontal white matter. EOS patients showed reduced activation in the entire network subserving working memory function particularly on the left hemisphere. -- Conclusions -- Abnormalities in parietal and cerebellar regions may be the earliest white matter changes in EOS.

The Neurodevelopmental Basis of Schizophrenia

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Publisher :
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.4/5 (351 download)

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Book Synopsis The Neurodevelopmental Basis of Schizophrenia by : John L. Waddington

Download or read book The Neurodevelopmental Basis of Schizophrenia written by John L. Waddington and published by . This book was released on 1996 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a critical update and synthesis of contemporary evidence for schizophrenia as a brain disease of early, neurodevelopmental origin; it does this through contributions from leading authorities in this field who work at multiple levels of biological and epidemiological enquiry. The work seeks both to integrate this evolving body of evidence and to examine the strengths and weaknesses of the neurodevelopmental model.

The Epidemiology of Schizophrenia

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Publisher : Cambridge University Press
ISBN 13 : 9780521121026
Total Pages : 0 pages
Book Rating : 4.1/5 (21 download)

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Book Synopsis The Epidemiology of Schizophrenia by : Robin M. Murray

Download or read book The Epidemiology of Schizophrenia written by Robin M. Murray and published by Cambridge University Press. This book was released on 2009-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.

Neuroimaging in Schizophrenia

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Publisher : Springer Nature
ISBN 13 : 3030352064
Total Pages : 432 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Neuroimaging in Schizophrenia by : Marek Kubicki

Download or read book Neuroimaging in Schizophrenia written by Marek Kubicki and published by Springer Nature. This book was released on 2020-02-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.

Cognitive Enhancement in Schizophrenia and Related Disorders

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Publisher : Cambridge University Press
ISBN 13 : 1107194784
Total Pages : 199 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Cognitive Enhancement in Schizophrenia and Related Disorders by : Matcheri Keshavan

Download or read book Cognitive Enhancement in Schizophrenia and Related Disorders written by Matcheri Keshavan and published by Cambridge University Press. This book was released on 2019-03-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.

Cognitive Impairment in Schizophrenia

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Publisher : Cambridge University Press
ISBN 13 : 1107013208
Total Pages : 341 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cognitive Impairment in Schizophrenia by : Philip D. Harvey

Download or read book Cognitive Impairment in Schizophrenia written by Philip D. Harvey and published by Cambridge University Press. This book was released on 2013-01-24 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.

Vulnerability to Psychosis

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Publisher : Psychology Press
ISBN 13 : 1136596380
Total Pages : 244 pages
Book Rating : 4.1/5 (365 download)

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Book Synopsis Vulnerability to Psychosis by : Paolo Fusar-Poli

Download or read book Vulnerability to Psychosis written by Paolo Fusar-Poli and published by Psychology Press. This book was released on 2013-06-17 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early clinical intervention in psychosis is now a major objective of mental health services and the development of specialist intervention services has greatly facilitated research on the early phases of this disorder. In this book, contributors provide a review of the neurobiological research in people at high risk of psychosis, focusing on the transition from being at a high risk state to their first episode. Contributors consider unaffected family members and twin studies as well as the individual’s data before and after the onset of the illness. The environmental factors that contribute to a psychotic episode are also examined. Vulnerability to Psychosis presents neurobiological findings in the context of what is now known about the psychopathology and cognitive impairments that are evident in people at high risk of psychosis. It will be essential reading for clinicians working with this client group, and will interest academics looking for state of the art information in this field.

Schizo-Obsessive Disorder

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Publisher : Cambridge University Press
ISBN 13 : 1107000122
Total Pages : 249 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Schizo-Obsessive Disorder by : Michael Poyurovsky

Download or read book Schizo-Obsessive Disorder written by Michael Poyurovsky and published by Cambridge University Press. This book was released on 2013-01-17 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.

MRI Atlas of Human White Matter

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Publisher : Academic Press
ISBN 13 : 0123820820
Total Pages : 266 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis MRI Atlas of Human White Matter by : Kenichi Oishi

Download or read book MRI Atlas of Human White Matter written by Kenichi Oishi and published by Academic Press. This book was released on 2010-11-12 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI Atlas of Human White Matter presents an atlas to the human brain on the basis of T 1-weighted imaging and diffusion tensor imaging. A general background on magnetic resonance imaging is provided, as well as the basics of diffusion tensor imaging. An overview of the principles and limitations in using this methodology in fiber tracking is included. This book describes the core white-matter structures, as well as the superficial white matter, the deep gray matter, and the cortex. It also presents a three-dimensional reconstruction and atlas of the brain white-matter tracts. The Montreal Neurological Institute coordinates, which are the most widely used, are adopted in this book as the primary coordinate system. The Talairach coordinate system is used as the secondary coordinate system. Based on magnetic resonance imaging and diffusion tensor imaging, the book offers a full segmentation of 220 white-matter and gray-matter structures with boundaries. Visualization of brain white matter anatomy via 3D diffusion tensor imaging (DTI) contrasts and enhances relationship of anatomy to function Full segmentation of 170+ brain regions more clearly defines structure boundaries than previous point-and-annotate anatomical labeling, and connectivity is mapped in a way not provided by traditional atlases

First Episode Psychosis

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Publisher : CRC Press
ISBN 13 : 9781853174353
Total Pages : 152 pages
Book Rating : 4.1/5 (743 download)

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Book Synopsis First Episode Psychosis by : Katherine J. Aitchison

Download or read book First Episode Psychosis written by Katherine J. Aitchison and published by CRC Press. This book was released on 1999-02-17 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.

Schizophrenia

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Publisher : MIT Press
ISBN 13 : 0262019620
Total Pages : 403 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Schizophrenia by : Steven M. Silverstein

Download or read book Schizophrenia written by Steven M. Silverstein and published by MIT Press. This book was released on 2013-11-15 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes

Youth Mental Health

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Publisher : Routledge
ISBN 13 : 1000292606
Total Pages : 335 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Youth Mental Health by : Alison R. Yung

Download or read book Youth Mental Health written by Alison R. Yung and published by Routledge. This book was released on 2020-12-30 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the field of youth mental health and why it is a specialty distinct from both child and adolescent and adult mental health. Youth Mental Health: Approaches to Emerging Mental Ill-Health in Young People examines issues such as mental health literacy, e-Health, family, psychological, vocational and pharmacological interventions. The authors also discuss issues that are particularly pertinent to young people, such as suicidality, substance abuse, gender identity and sexuality, attention deficit disorder and eating disorders. Taking a preventative focus, this book presents evidence for youth mental health as an important and growing field, makes the case for the reform of existing service structures to better serve this group and outlines the latest specialised approaches to treatment. Drawing on the knowledge and expertise of leading thinkers in youth mental health, this book is instrumental for mental health professionals who wish to design new specialised mental health systems for young people.

Advances in Schizophrenia Research 2009

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Publisher : Springer Science & Business Media
ISBN 13 : 1441909133
Total Pages : 461 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Advances in Schizophrenia Research 2009 by : Wagner F. Gattaz

Download or read book Advances in Schizophrenia Research 2009 written by Wagner F. Gattaz and published by Springer Science & Business Media. This book was released on 2009-11-12 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia remains an important challenge to psychiatry, with its causes and underlying brain mechanisms yet to be fully revealed. Currently available treatments are neither universally effective nor without unwanted effects. These aspects, together with the high prevalence of schizophrenia, its often debilitating nature, and the associated family and social burden, make this mental disorder one of the most complex public health issues of our times. The purpose of the Advances in Schizophrenia Research series is to provide comprehensive periodic reviews of the wide range of research studies carried out around the world, with the dual purpose of solving the schizophrenia puzzle, and providing clues to new forms of treatment and prevention for this disorder. A special feature of the series is its broad scope, virtually encompassing all fields of schizophrenia research: epidemiology and risk factors; psychopathology; diagnostic boundaries; cognition; outcome and prognosis; pathophysiology; genetics; pharmacological and psychological forms of treatment and rehabilitation; community care; and stigmatization.

Reducing Risks for Mental Disorders

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Publisher : National Academies Press
ISBN 13 : 0309049393
Total Pages : 636 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Reducing Risks for Mental Disorders by : Institute of Medicine

Download or read book Reducing Risks for Mental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.

Recovery from Schizophrenia

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Publisher : Psychology Press
ISBN 13 : 0415212677
Total Pages : 410 pages
Book Rating : 4.4/5 (152 download)

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Book Synopsis Recovery from Schizophrenia by : Richard Warner

Download or read book Recovery from Schizophrenia written by Richard Warner and published by Psychology Press. This book was released on 2004 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Recovery from Schizophrenia' demonstrates convincingly, but controversially, how political, economic and labour market forces shape social responses to the mentally ill, mould psychiatric treatment philosophy, and influence the onset and course of one of the most common forms of mental illness.