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Thrombinits Key Role In Thrombogenesis Implications For Its Inhibition
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Book Synopsis ThrombinIts Key Role in Thrombogenesis-Implications for Its Inhibition by : Michael R. Buchanan
Download or read book ThrombinIts Key Role in Thrombogenesis-Implications for Its Inhibition written by Michael R. Buchanan and published by CRC Press. This book was released on 1994-10-03 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new multi-authored book reviews the current understanding of the role of thrombin in venous and arterial thrombosis and its inhibition in the clinical setting. Heparin, the most widely used antithrombotic, does not effectively regulate thrombin or its formation. Accumulating evidence suggests that other antithrombins are effective in some of the situations where heparin is not. Discussions include the current knowledge on antithrombotic prophylaxis and therapy, from the perspective of the role in thrombin in venous and arterial vascular disease, the limitations of the current anticoagulant therapies, and potential and limitations of newer antithrombins currently being tested in several experimental and clinical settings. Thrombin helps the clinician to better rationalize the use of specific antithrombins in the prevention and management of thrombotic disease and provides the basic scientist with a better understanding of the goals the clinician attempts to achieve with antithrombotic therapy.
Download or read book Thrombin written by Stephanie J. Brister and published by . This book was released on 1995 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :V.S. Blanchette Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318030260 Total Pages :360 pages Book Rating :4.3/5 (18 download)
Book Synopsis SickKids Handbook of Pediatric Thrombosis and Hemostasis by : V.S. Blanchette
Download or read book SickKids Handbook of Pediatric Thrombosis and Hemostasis written by V.S. Blanchette and published by Karger Medical and Scientific Publishers. This book was released on 2016-12-22 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and extended edition of the SickKids Handbook takes the reader through the entire field of pediatric thrombosis and hemostasis. An introductory section concisely explains the complex pathophysiology of thrombosis and hemostasis. The chapters that follow include practical, evidence-based information on the diagnosis and management of inherited and acquired bleeding disorders and thrombotic events of the venous, arterial, cardiac and central nervous systems that affect children. Special features include practical clinical algorithms and appendices that cite normal laboratory reference ranges, as well as recommended dosages of blood products and major hemostatic agents. A stand-alone chapter is dedicated to developmental hemostasis and bleeding in the neonate. A chapter on antithrombotic therapy in children gives succinct information on the old and new anticoagulants, antiplatelet drugs and thrombolytic agents. Written and reviewed by international experts in the field, this handbook is intended for health care professionals involved in the assessment and care of children with inherited and acquired bleeding and clotting disorders, including general and specialist pediatricians (in particular intensivists, neonatologists, cardiologists/cardiac surgeons, rheumatologists and nephrologists), hematologists/oncologists (pediatric and adult), as well as medical trainees, nurses, nurse practitioners and pharmacists.
Book Synopsis Serpin Structure and Evolution by : James Whisstock
Download or read book Serpin Structure and Evolution written by James Whisstock and published by Academic Press. This book was released on 2011-11-16 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems. This volume in the Methods in Enzymology series comprehensively covers the topic of serpins With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems
Book Synopsis Williams Manual of Hematology, Tenth Edition by : Marshall A. Lichtman
Download or read book Williams Manual of Hematology, Tenth Edition written by Marshall A. Lichtman and published by McGraw Hill Professional. This book was released on 2022-04-08 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: A full-color clinical reference covering both common and uncommon blood disorders—distilled from the world’s leading hematology text Williams Manual of Hematology, Tenth Edition provides a concise, easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, this portable guide has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. This updated edition reflects the latest research and includes more than 100 full-color clinical photographs. Concise but comprehensive, this complete guide includes sections on: Initial Clinical Evaluation Disorders of Red Cells Disorders of Granulocytes Disorders of Monocytes and Macrophages Principles of Therapy for Neoplastic Hematological Disorders The Clonal Myeloid Disorders The Polyclonal Lymphoid Diseases The Clonal Lymphoid and Plasma Cell Diseases Disorders of Platelet and Hemostasis Disorders of Coagulation Proteins Thrombosis and Antithrombotic Therapy Transfusion and Hemapheresis
Book Synopsis Congenital Bleeding Disorders by : Akbar Dorgalaleh
Download or read book Congenital Bleeding Disorders written by Akbar Dorgalaleh and published by Springer. This book was released on 2018-07-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Book Synopsis Congenital Bleeding Disorders by : Akbar Dorgalaleh
Download or read book Congenital Bleeding Disorders written by Akbar Dorgalaleh and published by Springer Nature. This book was released on 2024-01-28 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This significantly updated new edition describes in detail the clinical presentations, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Book Synopsis The Concise Manual of Apheresis Therapy by : Eisei Noiri
Download or read book The Concise Manual of Apheresis Therapy written by Eisei Noiri and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocket-sized manual serves as a concise and ideal reference work for therapeutic approaches using apheresis, Covering both basic theory and clinical details to facilitate improved treatment and patient outcomes, the text considers a variety of diseases, including myasthenia gravis, multiple sclerosis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, nephrotic syndrome, TTP/TMA, dilated cardiomyopathy, and many other conditions. The books also reviews the growing trend towards adopting this unique therapy for a wide range of health management issues such as morbid obesity and/or type 2 diabetes, and for lowering LDL-cholesterol (cholesterol apheresis) in patients unresponsive to medication or lifestyle modification.
Book Synopsis 14th International Congress on Thrombosis by :
Download or read book 14th International Congress on Thrombosis written by and published by . This book was released on 1996 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Lipidology: A Companion to Braunwald's Heart Disease E-Book by : Christie M. Ballantyne
Download or read book Clinical Lipidology: A Companion to Braunwald's Heart Disease E-Book written by Christie M. Ballantyne and published by Elsevier Health Sciences. This book was released on 2014-11-14 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Lipidology, a companion to Braunwald's Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style. - Get authoritative guidance from some of the foremost experts in the field. - Easily access key content with help from treatment algorithms. - Access options and evidence-based solutions for every type of patient scenario, as well as the latest clinical guidelines and clinically relevant evidence on risk assessment, special patient populations, and therapy, including recently approved and experimental therapies. - Remain at the forefront of the cardiology field with up-to-date chapters on treatment guidelines; diet, exercise, and weight loss; pharmacologic therapies such as statins, omega-3 fatty acids, and combination therapy; evolving targets of therapy such as PCSK9 inhibition, CETP inhibition, and inflammation - Prepare for special patient populations such as children and adolescents; women and the elderly; transplant recipients; HIV patients; and those with chronic renal disease, familial hypercholesterolemia, other severe hypercholesterolemias, diabetes, or other metabolic syndromes. - Take advantage of a format that follows that of the well-known and internationally recognized Braunwald's Heart Disease. - Expert Consult eBook version included with purchase.
Book Synopsis The Chemical Biology of Thrombin by : Roger L. Lundblad
Download or read book The Chemical Biology of Thrombin written by Roger L. Lundblad and published by . This book was released on 2023-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology of Thrombin is a comprehensive review of thrombin as regulatory protease, perhaps one of the most important enzymes in hemostasis. It focuses on work from 1970's to the present time. Thrombin has some emerging therapeutic uses such the treatment of pseudoaneurysms and an important role in the extravascular space.
Download or read book Thrombosis and Haemostasis written by and published by . This book was released on 2007 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Applied Basic Science for Basic Surgical Training E-Book by : Andrew T Raftery
Download or read book Applied Basic Science for Basic Surgical Training E-Book written by Andrew T Raftery and published by Elsevier Health Sciences. This book was released on 2011-12-22 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. It has been written to encompass the basic anatomy, physiology and pathology required by the syllabus of the UK Royal Colleges and the Intercollegiate Surgical Curriculum Project. For this Second Edition many of the chapters have been updated, especially the chapters on immunology, basic microbiology, the endocrine and locomotor systems and the breast. An attempt has been made throughout to indicate the clinical relevance of the facts and the reason for learning them. There are several new contributors to the author team, all of whom are experts in their field and many of them are, or have been, experienced examiners at the various UK Royal Colleges. Brings together three basic sciences in one book and presents them in an integrated format. Presents the sciences at the right level for surgical trainees. Written in a straightforward and readable style. Thoroughly revised to take account of latest changes in basic surgical training, especially the chapters on immunology, basic microbiology, the endocrine and locomotor systems and the breast
Download or read book Hemomath written by Antonio Fasano and published by Springer. This book was released on 2017-10-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates applications of mathematics to various processes (physiological or artificial) involving flowing blood, including hemorheology, microcirculation, coagulation, kidney filtration and dialysis, offering a historical overview of each topic. Mathematical models are used to simulate processes normally occurring in flowing blood and to predict the effects of dysfunctions (e.g. bleeding disorders, renal failure), as well as the effects of therapies with an eye to improving treatments. Most of the models have a completely new approach that makes patient-specific simulations possible. The book is mainly intended for mathematicians interested in medical applications, but it is also useful for clinicians such as hematologists, nephrologists, cardio-surgeons, and bioengineers. Some parts require no specific knowledge of mathematics. The book is a valuable addition to mathematics, medical, biology, and bioengineering libraries.
Book Synopsis Transfusion Medicine and Hemostasis by : Beth H. Shaz
Download or read book Transfusion Medicine and Hemostasis written by Beth H. Shaz and published by Newnes. This book was released on 2013-05-13 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). - Updated content covers new coagulation tests, cellular therapies, and quality control issues - Easy to use, with focused, well-defined chapters in a standardized format throughout - Offers quick "cross-reference" lists at the end of each chapter - Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
Book Synopsis Williams Manual of Hematology, Ninth Edition by : Marshall A. Lichtman
Download or read book Williams Manual of Hematology, Ninth Edition written by Marshall A. Lichtman and published by McGraw Hill Professional. This book was released on 2017-01-20 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: A full-color clinical reference covering both common and uncommon blood disorders – referenced to the world’s leading hematology text Williams Manual of Hematology, Ninth Edition provides a quick-access summary of the epidemiology, etiology, pathogenesis, diagnostic criteria, differential diagnosis, and therapy of blood cell and coagulation protein disorders. The 93 chapters of the Manual are a distillation of the disease- and therapy-focused chapters from the Ninth Edition of Williams Hematology. The book has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. Concise but comprehensive, this complete guide includes sections on: • Initial Clinical Evaluation • Disorders of Red Cells • Disorders of Granulocytes • Disorders of Monocytes and Macrophages • Principles of Therapy for Neoplastic Hematological Disorders • The Clonal Myeloid Disorders • The Polyclonal Lymphoid Diseases • The Clonal Lymphoid and Plasma Cell Diseases • Disorders of Platelet and Hemostasis • Disorders of Coagulation Proteins • Thrombosis and Antithrombotic Therapy • Transfusion and Hemapheresis
Book Synopsis Biology of the Arterial Wall by : Bernard I. Levy
Download or read book Biology of the Arterial Wall written by Bernard I. Levy and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of the Arterial Wall is intended as a general reference text concerned with the biology of the vascular cells and the blood vessel wall under physiological and pathological conditions. One of the major functions of the arteries is to maintain a continuous blood flow to the organs whatever the pressure conditions, thanks to the vasomotor tone of the smooth muscle cells. Great advances have been made over the last decade in the understanding of the endothelial cells as integrators and transducers of signals originating from the blood stream. The pluripotent control functions of the endothelial cells in the vessel wall are now well recognized. A review of endothelial functions and dysfunctions is presented. Cell biology and molecular genetic studies have now identified an array of molecules elaborated by endothelial cells and vascular smooth muscle cells and by the blood-borne elements which interact with artery cells, defending the artery against injury and modulating evolving abnormal processes. Molecules which induce or inhibit endothelial and/or smooth muscle cells are currently under great scrutiny. Angiogenesis, which plays a major role in tumor growth, but may also be beneficial as a healing process in muscle ischemia, is discussed. Apoptosis, or programmed cell death, has only recently been recognized as an essential process in blood vessel modeling and remodeling. An overview of apoptosis in the vascular system is presented. It is increasingly evident that the adjustments of the blood vessel wall are made in the presence of deforming disease processes such as hypertension and atherosclerosis. The second part of the book is concerned with the blood vessel wall in disease conditions. Several chapters review the role of the vessel and vascular cells in inflammation, and vascular remodeling during arterial hypertension and aging. One chapter is devoted to atherogenesis, atheroma and plaque instability, followed by the pathophysiology of post-angioplasty restenosis, which is a crucial issue in modern interventional cardiology.
