Therapeutics for Ebola virus disease, 19 August 2022

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Author :
Publisher : World Health Organization
ISBN 13 : 9240055746
Total Pages : 44 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Therapeutics for Ebola virus disease, 19 August 2022 by :

Download or read book Therapeutics for Ebola virus disease, 19 August 2022 written by and published by World Health Organization. This book was released on 2022-08-19 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ebola virus disease (EVD) is a life-threatening disease caused by Ebola virus (EBOV; Zaire ebolavirus). Viruses of the genus Ebolavirus (of the family Filoviridae) can cause life-threatening disease. EBOV causes outbreaks of EVD, historically the most severe and most frequent. This guidance, due to the evidence available, is directed only to the treatment of EVD, the disease caused by EBOV (Zaire ebolavirus). During early EVD, patients present with a non-specific febrile illness, followed by gastrointestinal signs and symptoms that frequently lead to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. EVD case fatality remains high, with a pooled case fatality rate of 60% (95% confidence interval [CI]: 47–73%) in outbreaks from 2010–2020. Following the publication of an RCT demonstrating superior efficacy of two EVD therapeutics, in comparison to the ZMapp control arm, WHO proposed to develop a new guideline. This is a new guideline written to accompany the optimized supportive care (oSoC) for EVD standard operating procedures. The guideline aims to summarize high quality evidence for EVD therapeutics and make recommendations for their use.

Ebola and Marburg Viruses

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Author :
Publisher : Garland Science
ISBN 13 : 9780954523237
Total Pages : 392 pages
Book Rating : 4.5/5 (232 download)

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Book Synopsis Ebola and Marburg Viruses by : Hans-Dieter Klenk

Download or read book Ebola and Marburg Viruses written by Hans-Dieter Klenk and published by Garland Science. This book was released on 2004 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Clinical Management of Patients with Viral Haemorrhagic Fever

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Publisher : World Health Organization
ISBN 13 : 9241549602
Total Pages : 203 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Clinical Management of Patients with Viral Haemorrhagic Fever by : World Health Organization

Download or read book Clinical Management of Patients with Viral Haemorrhagic Fever written by World Health Organization and published by World Health Organization. This book was released on 2016-05-03 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".

Minimum standards and recommendations for medical teams responding to highly infectious disease outbreaks

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Publisher : World Health Organization
ISBN 13 : 9240092889
Total Pages : 266 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Minimum standards and recommendations for medical teams responding to highly infectious disease outbreaks by : World Health Organization

Download or read book Minimum standards and recommendations for medical teams responding to highly infectious disease outbreaks written by World Health Organization and published by World Health Organization. This book was released on 2024-06-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases with epidemic potential remain a significant and constant threat to the health and security of populations around the world, requiring robust health emergency preparedness, readiness and response systems and capacities at local and national levels. Emergency Medical Teams (EMTs), the EMT Initiative and its global network focus on establishing common quality standards and recommendations for medical teams to respond to health emergencies rapidly and effectively, as well as strengthening and supporting national capacities through strong collaboration and coordination. This publication defines minimum standards for the establishment of such critical capacities in a predictable and quality assured manner, and will enhance the interoperability between national, regional, and international capacities. This will contribute to the development and classification of respective specialized care teams (SCT) within the EMT framework and will provide guidance to member states, ministries of health, national and international EMTs and other key stakeholders to develop capacities and trainings, preparing for, or responding to outbreaks of highly infectious diseases.

GeNeDis 2020

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Author :
Publisher : Springer Nature
ISBN 13 : 3030787710
Total Pages : 391 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis GeNeDis 2020 by : Panayiotis Vlamos

Download or read book GeNeDis 2020 written by Panayiotis Vlamos and published by Springer Nature. This book was released on 2022-01-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.

Disease Control Priorities, Third Edition (Volume 6)

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Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Emerging Viral Diseases

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Publisher : National Academies Press
ISBN 13 : 0309314003
Total Pages : 310 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Emerging Viral Diseases by : Institute of Medicine

Download or read book Emerging Viral Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Drug-Induced Liver Injury

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Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

How to Prevent the Next Pandemic

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Author :
Publisher : Vintage
ISBN 13 : 0593534492
Total Pages : 235 pages
Book Rating : 4.5/5 (935 download)

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Book Synopsis How to Prevent the Next Pandemic by : Bill Gates

Download or read book How to Prevent the Next Pandemic written by Bill Gates and published by Vintage. This book was released on 2022-05-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Governments, businesses, and individuals around the world are thinking about what happens after the COVID-19 pandemic. Can we hope to not only ward off another COVID-like disaster but also eliminate all respiratory diseases, including the flu? Bill Gates, one of our greatest and most effective thinkers and activists, believes the answer is yes. The author of the #1 New York Times best seller How to Avoid a Climate Disaster lays out clearly and convincingly what the world should have learned from COVID-19 and what all of us can do to ward off another catastrophe like it. Relying on the shared knowledge of the world’s foremost experts and on his own experience of combating fatal diseases through the Gates Foundation, Gates first helps us understand the science of infectious diseases. Then he shows us how the nations of the world, working in conjunction with one another and with the private sector, how we can prevent a new pandemic from killing millions of people and devastating the global economy. Here is a clarion call—strong, comprehensive, and of the gravest importance.

Guidelines for the Treatment of Malaria. Third Edition

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Author :
Publisher : World Health Organization
ISBN 13 : 9241549122
Total Pages : 317 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Treatment of Malaria. Third Edition by : World Health Organization

Download or read book Guidelines for the Treatment of Malaria. Third Edition written by World Health Organization and published by World Health Organization. This book was released on 2015-08-13 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Gorilla Pathology and Health

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Publisher : Academic Press
ISBN 13 : 0128020857
Total Pages : 667 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Gorilla Pathology and Health by : John E Cooper

Download or read book Gorilla Pathology and Health written by John E Cooper and published by Academic Press. This book was released on 2016-12-21 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gorilla Pathology and Health: With a Catalogue of Preserved Materials consists of two cross-referenced parts. The first, the book itself, is a review of pathological changes and tissue responses in gorillas (Gorilla gorilla and G. beringei), with an emphasis on free-living animals, but also with reference to those in captivity. The comparative aspects are discussed, stressing the relevance of research to both gorillas and humans. What makes the publication truly unique, however, is the second part, a comprehensive descriptive catalogue of the location and nature of gorilla material in museums and scientific institutions throughout the world. This is of great consequence because free-living gorillas are strictly conserved with restricted access, so the location of a wealth of preserved tissues and other material that has been collected over the decades is a great benefit for research and study.This book can, and should, be used to gain cardinal knowledge regarding the biology and pathology of this genus. The combination of book and catalogue in this extensive compilation makes it an invaluable tool for all those concerned with the health, welfare, and conservation of gorillas, one of our nearest living relatives. - Brings together studies, data, and clinical practice from difficult-to-access or obscure journals and NGO reports, in different languages, for all interested parties and practitioners - Provides perspectives on existing research in gorilla pathology, both for those studying conservation practices and those seeking an understanding of comparable diseases in humans - Includes illustrative figures on gross and microscopic pathological changes, museum specimens, photos of field necropsy and techniques, and examples of laboratory tests - Features an extensive list of references and further reading, in different languages - Incorporates a comprehensive, descriptive catalogue of gorilla material from around the world

Immunologic Concepts in Transfusion Medicine

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323675107
Total Pages : 382 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Immunologic Concepts in Transfusion Medicine by : Robert W Maitta

Download or read book Immunologic Concepts in Transfusion Medicine written by Robert W Maitta and published by Elsevier Health Sciences. This book was released on 2019-08-27 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients. - Complies the knowledge and expertise of Dr. Robert Maitta, an expert in immune responses and antibody function/structure studies. - Helps clinicians in the daily practice of caring for patients in need of transfusion support, as well as physicians in training when considering utilizing blood transfusions in a limited scope or in the setting of massive transfusion. - Includes an immunology primer as an introduction to in-depth chapters covering allergic immune reactions to blood components, transfusion-related immunomodulation, fetal and neonatal alloimmune thrombocytopenia and neonatal neuthropenia, complications of haploidentical and mismatched HSC transplantation, chimeric antibody receptor therapies, and much more. - Consolidates today's available information on this timely topic into a single, convenient resource.

Fields Virology: Emerging Viruses

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975112555
Total Pages : 2737 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Fields Virology: Emerging Viruses by : Peter M. Howley

Download or read book Fields Virology: Emerging Viruses written by Peter M. Howley and published by Lippincott Williams & Wilkins. This book was released on 2020-02-11 with total page 2737 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.

Identifying Future Disease Hot Spots

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Publisher : Rand Corporation
ISBN 13 : 0833095749
Total Pages : 97 pages
Book Rating : 4.8/5 (33 download)

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Book Synopsis Identifying Future Disease Hot Spots by : Melinda Moore

Download or read book Identifying Future Disease Hot Spots written by Melinda Moore and published by Rand Corporation. This book was released on 2016-09-12 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Infectious Disease Vulnerability Index is intended to inform actions for preparedness and response to infectious disease outbreaks and foster greater resiliency of national health systems worldwide.

Pregnant in the Time of Ebola

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Author :
Publisher : Springer
ISBN 13 : 9783319976365
Total Pages : 487 pages
Book Rating : 4.9/5 (763 download)

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Book Synopsis Pregnant in the Time of Ebola by : David A. Schwartz

Download or read book Pregnant in the Time of Ebola written by David A. Schwartz and published by Springer. This book was released on 2019-01-15 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the deadliest Ebola outbreak in history examines its devastating effects on West Africa’s most vulnerable populations: pregnant women and children. Noted experts across disciplines assess health care systems’ responses to the epidemic in Liberia, Guinea, and Sierra Leone, emphasizing key areas such as pregnancy, prenatal services, childbirth, neonatal care, and survivor health among pregnant and non-pregnant women. The 30 chapters hone in on gender-based social issues exacerbated during the outbreak, from violence against women and girls to barriers to female education. At the same time, chapters pinpoint numerous areas for service delivery and policy improvements for more coordinated, effective, and humane actions during future pandemics. A sampling of the topics: Ebola virus disease: perinatal transmission and epidemiology Comprehensive clinical care for children with Ebola virus disease Maternal and reproductive rights: Ebola and the law in Liberia Ebola-related complications for maternal, newborn, and child health service delivery and utilization in Guinea The Ebola epidemic halted female genital cutting in Sierra Leone—temporarily Maternity care for Ebola at Médecins Sans Frontières centers Stigmatization of pregnant women with and without Ebola Exclusion of women and infants from Ebola treatment trials Role of midwives during the Ebola epidemic Pregnant in the Time of Ebola is a powerful resource for public health specialists, anthropologists, social scientists, physicians, epidemiologists, nurses, midwives, and governmental and non-governmental agency staff studying the effects of the epidemic on women and children as a result of the most widespread Ebola outbreak to date.

Conn's Current Therapy 2022

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323833799
Total Pages : 1581 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Conn's Current Therapy 2022 by : Rick D. Kellerman

Download or read book Conn's Current Therapy 2022 written by Rick D. Kellerman and published by Elsevier Health Sciences. This book was released on 2021-12-21 with total page 1581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trusted by clinicians for nearly 75 years, Conn’s Current Therapy presents today’s evidence-based information along with the personal experience and discernment of expert physicians. The 2022 edition is an excellent resource for a wide range of healthcare providers, including primary care, subspecialists, and allied health, providing current treatment information in a concise yet in-depth format. More than 300 topics have been carefully reviewed and updated to bring you state-of-the-art content in even the most rapidly changing areas of medicine. Offers personal approaches from recognized leaders in the field, covering common complaints, acute diseases, and chronic illnesses along with the most current evidence-based clinical management options. Follows a consistent, easy-to-use format throughout, with diagnosis, therapy, drug protocols, and treatment pearls presented in quick-reference boxes and tables for point-of-care answers to common clinical questions. Includes new and significantly revised chapters on COVID-19 and post-COVID syndrome, pyoderma gangrenosum, mitochondrial disease, gender affirming care, stem cell therapy, and artificial intelligence. Incorporates more electronic links throughout the text that connect the reader to apps and clinical prediction tools that can easily be accessed in practice. Features thoroughly reviewed and updated information from many new authors who offer a fresh perspective and their unique personal experience and judgment. Provides current drug information thoroughly reviewed by PharmDs. Features nearly 300 images, including algorithms, anatomical illustrations, and photographs, that provide useful information for diagnosis.

Global Technical Strategy for Malaria 2016-2030

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Author :
Publisher : World Health Organization
ISBN 13 : 9241564997
Total Pages : 35 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Global Technical Strategy for Malaria 2016-2030 by : World Health Organization

Download or read book Global Technical Strategy for Malaria 2016-2030 written by World Health Organization and published by World Health Organization. This book was released on 2015-11-04 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization's Global Technical Strategy for Malaria 2016- 2030 has been developed with the aim to help countries to reduce the human suffering caused by the world's deadliest mosquito-borne disease. Adopted by the World Health Assembly in May 2015 it provides comprehensive technical guidance to countries and development partners for the next 15 years emphasizing the importance of scaling up malaria responses and moving towards elimination. It also highlights the urgent need to increase investments across all interventions - including preventive measures diagnostic testing treatment and disease surveillance- as well as in harnessing innovation and expanding research. By adopting this strategy WHO Member States have endorsed the bold vision of a world free of malaria and set the ambitious new target of reducing the global malaria burden by 90% by 2030. They also agreed to strengthen health systems address emerging multi-drug and insecticide resistance and intensify national cross-border and regional efforts to scale up malaria responses to protect everyone at risk.