Therapeutic Rhodium Complexes

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Publisher : Springer Nature
ISBN 13 : 3031356314
Total Pages : 84 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Therapeutic Rhodium Complexes by : Afzal Hussain

Download or read book Therapeutic Rhodium Complexes written by Afzal Hussain and published by Springer Nature. This book was released on 2023-06-29 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as antibacterial agents or antiviral agents are also analyzed, among others. Their mechanism of action is overviewed in detail, and the authors thoroughly comment on the challenges and future outlooks of research in the development of rhodium metallodrugs. This title highlights the important research carried out in the development of therapeutic rhodium complexes and is of great interest to graduates and researchers working in the area of rhodium-based therapeutic drugs.

DNA-targeting Molecules as Therapeutic Agents

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Publisher : Royal Society of Chemistry
ISBN 13 : 1782629920
Total Pages : 432 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis DNA-targeting Molecules as Therapeutic Agents by : Michael J. Waring

Download or read book DNA-targeting Molecules as Therapeutic Agents written by Michael J. Waring and published by Royal Society of Chemistry. This book was released on 2018-03-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been remarkable advances towards discovering agents that exhibit selectivity and sequence-specificity for DNA, as well as understanding the interactions that underlie its propensity to bind molecules. This progress has important applications in many areas of biotechnology and medicine, notably in cancer treatment as well as in future gene targeting therapies. The editor and contributing authors are leaders in their fields and provide useful perspectives from diverse and interdisciplinary backgrounds on the current status of this broad area. The role played by chemistry is a unifying theme. Early chapters cover methodologies to evaluate DNA-interactive agents and then the book provides examples of DNA-interactive molecules and technologies in development as therapeutic agents. DNA-binding metal complexes, peptide and polyamide–DNA interactions, and gene targeting tools are some of the most compelling topics treated in depth. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.

Metallotherapeutic Drugs and Metal-Based Diagnostic Agents

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Publisher : John Wiley & Sons
ISBN 13 : 0470864044
Total Pages : 638 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Metallotherapeutic Drugs and Metal-Based Diagnostic Agents by : Marcel Gielen

Download or read book Metallotherapeutic Drugs and Metal-Based Diagnostic Agents written by Marcel Gielen and published by John Wiley & Sons. This book was released on 2005-09-01 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are an astonishing number and variety of roles that metals play in contemporary medicine. This book contains information on the medicinal uses of inorganics, that is, of elements such as boron, lithium, selenium, to name a few, as well as metal-containing species. In keeping with the notion that healthy mammals rely on (bio-essential) metals for the normal functioning of approximately a third of their proteins and enzymes, a large number of drugs are metal-based and considerable effort is being devoted to developing both second- and third-generation drugs as well as generating novel metal-based drugs. While there is no doubt that there is an emphasis on 'Metallotherapeutics' throughout the volume, the use of metals in medicine is not restricted to metal-based drugs. The following are also covered: non-invasive radiopharmaceuticals Magnetic Resonance Imaging (MRI) mineral supplements From the foregoing and, more importantly, from the contents of the various Chapters, the reader will gain an appreciation of the very real role metal-based drugs play in modern medicine and of the considerable effort being devoted to the development of novel complexes with greater efficacy as therapeutic and diagnostic agents.

Metal Compounds in Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9401112525
Total Pages : 269 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Metal Compounds in Cancer Therapy by : S.P. Fricker

Download or read book Metal Compounds in Cancer Therapy written by S.P. Fricker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora tories throughout Europe and America and represent the many disci plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.

Frontiers in Anti-Infective Drug Discovery

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Publisher : Bentham Science Publishers
ISBN 13 : 1608051587
Total Pages : 436 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Frontiers in Anti-Infective Drug Discovery by : Atta-ur- Rahman

Download or read book Frontiers in Anti-Infective Drug Discovery written by Atta-ur- Rahman and published by Bentham Science Publishers. This book was released on 2011-08-11 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Frontiers in Anti-Infective Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and

Nucleic Acid-metal Ion Interactions

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854041958
Total Pages : 449 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Nucleic Acid-metal Ion Interactions by : Nicholas V. Hud

Download or read book Nucleic Acid-metal Ion Interactions written by Nicholas V. Hud and published by Royal Society of Chemistry. This book was released on 2009 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a perspective on nucleic acid-metal ion interactions with an emphasis on experimental biophysical studies which will prove indispensable to biophysicists and molecular biologists.

Cancer Treatment Reports

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Author :
Publisher :
ISBN 13 :
Total Pages : 1068 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Cancer Treatment Reports by :

Download or read book Cancer Treatment Reports written by and published by . This book was released on 1979 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Neutron Capture Therapy for Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1461533848
Total Pages : 641 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Progress in Neutron Capture Therapy for Cancer by : B.J. Allen

Download or read book Progress in Neutron Capture Therapy for Cancer written by B.J. Allen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the many advances made in the diagnosis and therapy of cancer, the mortality rate is still about half that of the incidence rate. However, the odds are not evenly distributed. Prognosis for some cancers is good, but for others, few patients will survive 12 months. This latter group of cancers is characterised by a proclivity to disseminate malignant cells in the host organ. The degree of surgery possible may be limited by the critical nature of the organ, and chemotherapy and radiotherapy are of palliative value only. In some cases systemic metastases occur, but in other cases, failure to achieve local control results in death. First among these cancers are the high grade brain tumours, astrocytoma 3,4 and glioblastoma multiforme. Local control of these tumours should lead to cure. Other cancers melanoma metastatic to the brain, for which a useful palliative therapy is not yet available, and pancreatic cancer for which localised control at an early stage could bring about improved prognosis. Patients with these cancers have little grounds for hope. Our primary objective is to reverse this situation with Neutron Capture Therapy (NCT). The purpose of this fourth symposium is to hasten the day whereby patients with these cancers can reasonably hope for substantial remissions. The first symposium on NCT was held in Boston in 1983, followed by Tokyo in 1985 and Bremen, Germany in 1988.

Metals in Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1119191343
Total Pages : 480 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Metals in Medicine by : James C. Dabrowiak

Download or read book Metals in Medicine written by James C. Dabrowiak and published by John Wiley & Sons. This book was released on 2017-05-02 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from basic chemical principles, Metals in Medicine 2nd Edition describes a wide range of metal-based agents for treating and diagnosing disease. Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the first edition. Topics include: Metallo-Drugs and their action Platinum drugs for treating cancer Anticancer agents beyond cisplatin including ruthenium, gold, titanium and gallium Responsive Metal Complexes Treating arthritis and diabetes with metal complexes Metal complexes for killing bacteria, parasites and viruses Metal ion imbalance and its links to diseases including Alzheimer’s, Wilson’s and Menkes disease Metal complexes for detecting disease Nanotechnology in medicine Now in full colour, Metals in Medicine 2nd Edition employs real-life applications and chapter-end summaries alongside feature boxes and problems. It provides a complete and methodical examination of the use of metal complexes in medicine for advanced undergraduate and postgraduate students in medicinal inorganic chemistry, bioinorganic chemistry, biochemistry, pharmacology, biophysics, biology and bioengineering. It is also an invaluable resource for academic researchers and industrial scientists in inorganic chemistry, medicinal chemistry and drug development.

Nanomaterials for Photodynamic Therapy

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Publisher : Woodhead Publishing
ISBN 13 : 0323903541
Total Pages : 570 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanomaterials for Photodynamic Therapy by : Prashant Kesharwani

Download or read book Nanomaterials for Photodynamic Therapy written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2023-01-14 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Photodynamic Therapy takes a unique approach to this area, with a key focus on the use of nanomaterials and nanocarriers for photodynamic therapy (PDT). The book introduces the history and mechanism of action behind PDT, covering the variety of sensitizers currently available. Subsequent chapters review existing and emerging nanomaterials for PDT, including hydrogel nanocomposites, fullerenes, quantum dots, polymeric micelles, and more. Challenges and translational aspects of PDT are also discussed, touching on the issues and hindrances of drug resistant cancers.The book bridges the gap between the physics and clinical aspects of PDT, offering a unique nanomaterials-focused perspective. This book will prove useful for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists interested in cancer treatment. Reviews a broad range of nanomaterials for PDT, such as graphene oxide, dendrimers, solid lipid nanoparticles, and more Provides a helpful introduction to the history and mechanism of action behind PDT Discusses challenges in clinical translational, particularly in drug-resistant cancers

Biological and Medical Significance of Chemical Elements

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Publisher : Bentham Science Publishers
ISBN 13 : 9815179012
Total Pages : 351 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Biological and Medical Significance of Chemical Elements by : Irena Kostova

Download or read book Biological and Medical Significance of Chemical Elements written by Irena Kostova and published by Bentham Science Publishers. This book was released on 2023-10-27 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the fascinating interplay between chemical elements and biological life with Biological and Medical Significance of Chemical Elements. This comprehensive handbook delves into the pivotal role that various chemical elements from the periodic table play in the intricate web of life processes. Discover how these elements impact human health, influence drug development, and contribute to essential biological pathways. Key Features: - Provides information on the occurrence and classification of chemical elements in nature - Explains the biological functions of elements from different main groups (including s-, p-, d- and f-block elements) - Includes information about the biomedical significance of platinum metals, lanthanides, and actinides - Includes a list of references for further reading This book serves as an indispensable resource for anyone interested in the medical biochemistry of chemical elements

Current Research on Pre-clinical Aspects of Cancer Therapy

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Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Current Research on Pre-clinical Aspects of Cancer Therapy by : Current Cancer Research Project Analysis Center (U.S.)

Download or read book Current Research on Pre-clinical Aspects of Cancer Therapy written by Current Cancer Research Project Analysis Center (U.S.) and published by . This book was released on 1975 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1038 references to research projects being conducted in the United States and elsewhere. Entries arranged under 5 topics, e.g., Preclinical studies of anticancer drugs, Preclinical radiation therapy, and Preclinical immunotherapy. Entriesinclude title, researcher, address, contract number, summary, and supporting agency. Indexes by subjects, investigators, contractors, supporting agencies, and contractor numbers.

Iridium(III) in Optoelectronic and Photonics Applications

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Publisher : John Wiley & Sons
ISBN 13 : 1119007143
Total Pages : 736 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Iridium(III) in Optoelectronic and Photonics Applications by : Eli Zysman-Colman

Download or read book Iridium(III) in Optoelectronic and Photonics Applications written by Eli Zysman-Colman and published by John Wiley & Sons. This book was released on 2017-03-03 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental photophysical properties of iridium(III) materials make this class of materials the pre-eminent transition metal complex for use in optoelectronic applications. Iridium(III) in Optoelectronic and Photonics Applications represents the definitive account of photoactive iridium complexes and their use across a wide variety of applications. This two-volume set begins with an overview of the synthesis of these complexes and discusses their photophysical properties. The text highlights not only mononuclear complexes but also the properties of multinuclear and polymeric iridium-based materials and the assembly of iridium complexes into larger supramolecular architectures such as MOFs and soft materials. Chapters devoted to the use of these iridium-based materials in diverse optoelectronic applications follow, including: electroluminescent devices such as organic light emitting diodes (OLEDs) and light-emitting electrochemical cells (LEECs); electrochemiluminescence (ECL); bioimaging; sensing; light harvesting in the context of solar cell applications; in photoredox catalysis and as components for solar fuels. Although primarily targeting a chemistry audience, the wide applicability of these compounds transcends traditional disciplines, making this text also of use to physicists, materials scientists or biologists who have interests in these areas.

Biomedical Applications of Metals

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Publisher : Springer
ISBN 13 : 3319748149
Total Pages : 325 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Biomedical Applications of Metals by : Mahendra Rai

Download or read book Biomedical Applications of Metals written by Mahendra Rai and published by Springer. This book was released on 2018-02-24 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., “Ayurveda”. In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma’s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.

Toxicity Bibliography

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Publisher :
ISBN 13 :
Total Pages : 822 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Bibliography by :

Download or read book Toxicity Bibliography written by and published by . This book was released on 1977 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medicinal Organometallic Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642131840
Total Pages : 305 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Medicinal Organometallic Chemistry by : Gérard Jaouen

Download or read book Medicinal Organometallic Chemistry written by Gérard Jaouen and published by Springer Science & Business Media. This book was released on 2010-09-14 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule.

Comprehensive Inorganic Chemistry II

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Author :
Publisher : Newnes
ISBN 13 : 0080965296
Total Pages : 7694 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Inorganic Chemistry II by :

Download or read book Comprehensive Inorganic Chemistry II written by and published by Newnes. This book was released on 2013-07-23 with total page 7694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Inorganic Chemistry II, Nine Volume Set reviews and examines topics of relevance to today’s inorganic chemists. Covering more interdisciplinary and high impact areas, Comprehensive Inorganic Chemistry II includes biological inorganic chemistry, solid state chemistry, materials chemistry, and nanoscience. The work is designed to follow on, with a different viewpoint and format, from our 1973 work, Comprehensive Inorganic Chemistry, edited by Bailar, Emeléus, Nyholm, and Trotman-Dickenson, which has received over 2,000 citations. The new work will also complement other recent Elsevier works in this area, Comprehensive Coordination Chemistry and Comprehensive Organometallic Chemistry, to form a trio of works covering the whole of modern inorganic chemistry. Chapters are designed to provide a valuable, long-standing scientific resource for both advanced students new to an area and researchers who need further background or answers to a particular problem on the elements, their compounds, or applications. Chapters are written by teams of leading experts, under the guidance of the Volume Editors and the Editors-in-Chief. The articles are written at a level that allows undergraduate students to understand the material, while providing active researchers with a ready reference resource for information in the field. The chapters will not provide basic data on the elements, which is available from many sources (and the original work), but instead concentrate on applications of the elements and their compounds. Provides a comprehensive review which serves to put many advances in perspective and allows the reader to make connections to related fields, such as: biological inorganic chemistry, materials chemistry, solid state chemistry and nanoscience Inorganic chemistry is rapidly developing, which brings about the need for a reference resource such as this that summarise recent developments and simultaneously provide background information Forms the new definitive source for researchers interested in elements and their applications; completely replacing the highly cited first edition, which published in 1973