Therapeutic Applications Of Interleukin 2

Download Therapeutic Applications Of Interleukin 2 full books in PDF, epub, and Kindle. Read online Therapeutic Applications Of Interleukin 2 ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Therapeutic Applications of Interleukin-2

Author : Michael Atkins
Publisher : CRC Press
ISBN 13 : 9780824788094
Total Pages : 520 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Therapeutic Applications of Interleukin-2 by : Michael Atkins

Download or read book Therapeutic Applications of Interleukin-2 written by Michael Atkins and published by CRC Press. This book was released on 1993-03-08 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering everything from basic science to disease-specific clinical trials, current applications and future directions, this book discusses the novel biological response modifier interleukin-2. This immunoactive therapy is designed for use in the treatment of metastatic renal cancer and, possibly, melanoma and other malignancies. Examining the value and toxic manifestations of different treatment regimens, this text: describes the biochemistry of the IL-2 receptor, the activation of natural killer cells and the lymphokine-activated killer (LAK) cell phenomenon; explicates tumour-infiltrating lymphocytes and the effect of IL-2 on in vitro assays of immune function; emphasizes high-dose IL-2 therapy in renal cell carcinoma and malignant melanoma; reviews in detail IL-2 treatment of other solid tumours and haematologic malignancies; illustrates the use of lower dose regimens, regional administration and combinations of IL-2 with other therapies; elucidates toxicities associated with IL-2, their pathogenesis and clinical management; and highlights future developments, including gene therapy and the co-administration of cytokine antagonists to reduce toxicity.

The role of interleukin-2 in the treatment of cancer patients

Author : J. Wagstaff
Publisher : Springer Science & Business Media
ISBN 13 : 9401117535
Total Pages : 195 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!

Book Synopsis The role of interleukin-2 in the treatment of cancer patients by : J. Wagstaff

Download or read book The role of interleukin-2 in the treatment of cancer patients written by J. Wagstaff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant human interleukin-2 became available for clinical use in the mid 1980s. Recent years have seen an enormous amount of clinical research with this cytokine and interleukin-2 has now been registered for use in a number of European countries for the treatment of metastatic renal cell carcinoma. This book is designed to provide the clinical oncologist wishing to use interleukin-2 with a basic background concerning the biology of the agent, a discussion concerning practical aspects, of its clinical use including management of toxicity and an overview of the clinical results together with a description of how this internesting cytokine might be developed in the future.

The Biology and Clinical Applications of Interleukin-2

Author : Robert C. Rees
Publisher : IRL Press
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Biology and Clinical Applications of Interleukin-2 by : Robert C. Rees

Download or read book The Biology and Clinical Applications of Interleukin-2 written by Robert C. Rees and published by IRL Press. This book was released on 1990 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular structure of interleukin-2 (IL-2) and that of its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumors. This book provides an up-to-date account of IL-2, its effect on lymphocyte function, and clinical applications. Internationally know experts review the molecular aspects of cell signalling, giving insight on the in vivo pathways of activation likely to be important in determining clinical responses. They also examine the use of cytokines, particularly IL-2, in the treatment of cancer, and describe the results of recent clinical trials using IL-2, as well as of adoptive cell therapy. Providing a clear account of recent progress, the book also reviews the problems involved in attempting to improve the therapeutic benefit of IL-2, along with the importance of mechanisms which subverse IL-2 responses. This is the most up-to-date account of molecular research and clinical trials in this area, and will be of great benefit to students and researchers in immunology, pharmacology, biochemistry, and oncology who are interested in this vitally important topic.

Clinical Applications of Cytokines

Author : Joost J. Oppenheim
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071290
Total Pages : 406 pages
Book Rating : 4.0/5 (712 download)

DOWNLOAD NOW!

Book Synopsis Clinical Applications of Cytokines by : Joost J. Oppenheim

Download or read book Clinical Applications of Cytokines written by Joost J. Oppenheim and published by Oxford University Press, USA. This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The driving force for research on cytokines has always been their clinical promise. Their biological properties suggested a key role in hematopoiesis, immunity, tumor genesis, hemostasis, vascularization, repair of connective tissues and integration of the immune system with the neuroendocrine system. Animal studies have shown that cytokines could be used as effective biotherapeutics with easily manageable and reversible toxicities. Clinical trials have confirmed these findings, culminating in the licensing of a number of the cytokines such as interferon alpha, interferon gamma, interleukin 2, erythropoietin, granulocyte colony stimulating factor, and granulocyte-macrophage colony stimulating factor. Many other cytokines are in clinical trials. This is the first comprehensive volume on the cytokines written primarily from a medical perspective. After presenting background information about the structure, production, assays and systemic effects of cytokines and their receptors, it is organized around diseases and organ systems. Infectious diseases, autoimmunity, immunodeficiency states, defective hematopoiesis, allergies, injury repair, cancer, vascular and skin diseases, and neurological disorders are all covered. This work reviews the role that cytokines play in the pathogenesis, diagnosis and therapy of each disease. The authors assess both the current state of the art and the potential for future applications.

Immunotherapy

Author : Aung Naing
Publisher : Springer Nature
ISBN 13 : 3030793087
Total Pages : 445 pages
Book Rating : 4.0/5 (37 download)

DOWNLOAD NOW!

Book Synopsis Immunotherapy by : Aung Naing

Download or read book Immunotherapy written by Aung Naing and published by Springer Nature. This book was released on 2022-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.

Interleukin-2 and Killer Cells in Cancer

Author : Eva Lotzova
Publisher : CRC Press
ISBN 13 : 1351082248
Total Pages : 381 pages
Book Rating : 4.3/5 (51 download)

DOWNLOAD NOW!

Book Synopsis Interleukin-2 and Killer Cells in Cancer by : Eva Lotzova

Download or read book Interleukin-2 and Killer Cells in Cancer written by Eva Lotzova and published by CRC Press. This book was released on 2018-02-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

DOWNLOAD NOW!

Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Nanoscience in Dermatology

Author : Michael R. Hamblin
Publisher : Academic Press
ISBN 13 : 0128029455
Total Pages : 402 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Nanoscience in Dermatology by : Michael R. Hamblin

Download or read book Nanoscience in Dermatology written by Michael R. Hamblin and published by Academic Press. This book was released on 2016-08-13 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine. Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology Coherently structured book written by experts working in the fields covered

Cytokine Knockouts

Author : Scott K. Durum
Publisher : Springer Science & Business Media
ISBN 13 : 1475727534
Total Pages : 498 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Cytokine Knockouts by : Scott K. Durum

Download or read book Cytokine Knockouts written by Scott K. Durum and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: My personal history in the field of cytokines had an initial period of several years during which my student and then colleague, Werner Muller, tried in vain to attract me to them. My interest always vanished when I was confronted with complex data pointing to func tional redundancy of cytokines in cell culture systems. When gene targeting in the mouse germline became possible, this frustration came to an end. We and others immediately embarked on analyzing the in vivo function of cytokines and the problem of functional redundancy with this powerful new approach. The early cytokine gene knockouts performed by colleagues in Wiirzburg (IL-2) and by ourselves (IL-4 and IL-l 0) seemed to give clear answers and at the same time led to surprises: Each of these cytokines apparently had its own special and irreplaceable function, and this function could be quite distinct from what had been anticipated from functional experiments in vitro. Al though the latter finding is of course a wonderful incentive for fur ther research, the former is pleasing in a general sense since it highlights the value of each of those one hundred thousand genes or so in our genome, cherished by evolution to become respectable mem bers of the community. Even in the present era of "genomics" there will be no way around the careful functional analysis of each gene by itself.

Integrating Conventional and Chinese Medicine in Cancer Care

Author : Tai Lahans
Publisher : Elsevier Health Sciences
ISBN 13 : 0443100632
Total Pages : 414 pages
Book Rating : 4.4/5 (431 download)

DOWNLOAD NOW!

Book Synopsis Integrating Conventional and Chinese Medicine in Cancer Care by : Tai Lahans

Download or read book Integrating Conventional and Chinese Medicine in Cancer Care written by Tai Lahans and published by Elsevier Health Sciences. This book was released on 2007-06-05 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new clinical resource clearly explains how to approach integrated care in a way that combines Chinese herbal medicine with Western medicine to enhance and improve medical care for patients with cancer - without undermining or negatively impacting patients' medical treatment. Each chapter covers a different type of cancer, first introducing the conventional medical understanding of that cancer including its etiology, diagnosis, and treatment according to staging and type. The chapter then covers that cancer from the perspective of Oriental medicine. Case studies illustrate the integration of treatment for each cancer type, raising important issues and considerations associated with specific cancers and treatments. Formulas are presented within the context of conventional treatment, intended to enhance the effectiveness of treatment and/or treat side effects without undermining the treatment's function. Each formula is followed by a discussion of how and why the herbs are used, including classical Chinese theory and relevant pharmaceutical studies. Staging and the age and performance status of various patients is used as a means by which to explain how formulas are changed. Case studies explore issues related to the integration of treatment for each type of cancer.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128163674
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by : Prashant Kesharwani

Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-01-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

IASLC Thoracic Oncology E-Book

Author : Harvey Pass
Publisher : Elsevier Health Sciences
ISBN 13 : 0323527841
Total Pages : 960 pages
Book Rating : 4.3/5 (235 download)

DOWNLOAD NOW!

Book Synopsis IASLC Thoracic Oncology E-Book by : Harvey Pass

Download or read book IASLC Thoracic Oncology E-Book written by Harvey Pass and published by Elsevier Health Sciences. This book was released on 2017-04-21 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today’s best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. Features a new full-color design throughout, as well as updated diagnostic algorithms.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

DOWNLOAD NOW!

Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The Role of Interleukin-2 in the Treatment of Cancer Patients

Author : J. Wagstaff
Publisher :
ISBN 13 : 9789401117548
Total Pages : 204 pages
Book Rating : 4.1/5 (175 download)

DOWNLOAD NOW!

Book Synopsis The Role of Interleukin-2 in the Treatment of Cancer Patients by : J. Wagstaff

Download or read book The Role of Interleukin-2 in the Treatment of Cancer Patients written by J. Wagstaff and published by . This book was released on 2014-01-15 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Central Nervous System Metastases

Author : Manmeet Ahluwalia
Publisher : Springer Nature
ISBN 13 : 3030234177
Total Pages : 421 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Central Nervous System Metastases by : Manmeet Ahluwalia

Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Lymphohaematopoietic Growth Factors in Cancer Therapy II

Author : Roland Mertelsmann
Publisher : Springer Science & Business Media
ISBN 13 : 3642778011
Total Pages : 245 pages
Book Rating : 4.6/5 (427 download)

DOWNLOAD NOW!

Book Synopsis Lymphohaematopoietic Growth Factors in Cancer Therapy II by : Roland Mertelsmann

Download or read book Lymphohaematopoietic Growth Factors in Cancer Therapy II written by Roland Mertelsmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Introduction and Overview Lymphopoietic Growth Factors: Pathophysiology of T-Cell Mediated Shock Induced by Bacterial Superantigens - Natural Killer Cells and Interleukin-2-Activated Killer Cells - TumourImmunogenicity Induced by Exogenous Interleukins - Cytokine Gene Therapy of Cancer - Analysis of T-Cell Receptor Variability in Tumour Infiltrating Lymphocytes - Clinical Studies with Interleukin-2: An Overview - Clinical Trials with Local Administration of Lymphopoietic Growth Factors - Clinical Trials with Interlaukin-2. The Rome Experience. Haematopoietic Growth Factors: Lymphohaematopoietic Growth Factor Use in Lung Cancer Patients - Clinical Trials with Haematopoietic Growth Factors and Peripheral Blood Stem Cells.

Interleukins in Cancer Biology

Author : Arseniy Yuzhalin
Publisher : Academic Press
ISBN 13 : 0128013338
Total Pages : 361 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Interleukins in Cancer Biology by : Arseniy Yuzhalin

Download or read book Interleukins in Cancer Biology written by Arseniy Yuzhalin and published by Academic Press. This book was released on 2014-06-27 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer Categorizes and clarifies all interleukins based on their role in cancer Contains comprehensive and exhaustive information on each molecule