New Drugs, Fair Prices

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Author :
Publisher : Taylor & Francis
ISBN 13 : 1000781291
Total Pages : 285 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis New Drugs, Fair Prices by : Brian D. Smith

Download or read book New Drugs, Fair Prices written by Brian D. Smith and published by Taylor & Francis. This book was released on 2022-11-21 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Drugs, Fair Prices addresses the important question of how we might get the innovative new medicines we need at prices we can afford. Today, this debate is impassioned but sterile. One side calls for price controls, discounting their impact on investment in innovation. The other points to miraculous new therapies, disregarding their affordability and social inequity. This polarized argument creates more heat than light, threatening the social contract between the industry and society on which pharmaceutical innovation depends. This ground-breaking book takes a wholly new perspective on the issue and raises the debate to a more informed and productive level. Drawing on interviews with more than 70 experts across the pharmaceutical innovation world and combining a diverse literature from scientific, political, economic and business domains, it describes how a sustainable and affordable supply of new medicines is possible only by balancing pharmaceutical innovation’s complex, adaptive ecosystem. By considering how each of the ecosystem’s seven habitats work and interact with the others, it makes a comprehensive set of recommendations for achieving that ecosystem balance. The core message of New Drugs, Fair Prices is important to anyone who ever has needed or will ever need a medicine: we can have a sustainable supply of new medicines that are both innovative and affordable if we manage the pharmaceutical innovation ecosystem intelligently.

Happiness Quantified

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Publisher : Oxford University Press
ISBN 13 : 0199226148
Total Pages : 392 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Happiness Quantified by : Bernard M. S. van Praag

Download or read book Happiness Quantified written by Bernard M. S. van Praag and published by Oxford University Press. This book was released on 2008 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using German, British, Dutch, and Russian data, the authors cover a wide range of topics.

S. 334

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Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis S. 334 by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions

Download or read book S. 334 written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions and published by . This book was released on 2005 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Resistance to Targeted Therapies in Lymphomas

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Author :
Publisher : Springer Nature
ISBN 13 : 3030244245
Total Pages : 220 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Resistance to Targeted Therapies in Lymphomas by : Ana C. Xavier

Download or read book Resistance to Targeted Therapies in Lymphomas written by Ana C. Xavier and published by Springer Nature. This book was released on 2019-09-13 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the understanding of cancer cell biology and its microenvironment which has resulted in the development of biologic agents, also called "target" therapies. These therapies are more specific in targeting cancer cells either directly or via enhancement of the immune system. Many clinical studies have focused on biological agents in combination with traditional chemotherapy with the goal of improved outcomes, or reduced acute long term complications that are associated with lymphoma therapy. This volume will review different classes of "target" drugs that have been developed, approved, or are under investigation in the field of lymphoma therapy. The discussion will not only be on the understanding of the mechanisms of action or clinical response of those agents, but will also help the reader to understand the nature of lymphoma biology in patients who relapse or are refractor after exposure to those drugs. Contributors will discuss what is currently known about mechanisms of tumor-related or host-related resistance, and how to overcome this resistance. This understanding is crucial given the dismal outcomes of patients with relapsed or refractory lymphomas. The book provides a unique opportunity to review and reflect on the recent successes and pitfalls of the modern lymphoma therapy era.

PARP Inhibitors for Cancer Therapy

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Publisher : Humana Press
ISBN 13 : 3319141511
Total Pages : 590 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis PARP Inhibitors for Cancer Therapy by : Nicola J. Curtin

Download or read book PARP Inhibitors for Cancer Therapy written by Nicola J. Curtin and published by Humana Press. This book was released on 2015-06-13 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The “synthetic lethality” of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.

Nomination

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Publisher :
ISBN 13 :
Total Pages : 62 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nomination by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions

Download or read book Nomination written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions and published by . This book was released on 2003 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunotherapies for Acute Myeloid Leukemia

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Author :
Publisher : MDPI
ISBN 13 : 3039361104
Total Pages : 162 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Immunotherapies for Acute Myeloid Leukemia by : Jochen Greiner

Download or read book Immunotherapies for Acute Myeloid Leukemia written by Jochen Greiner and published by MDPI. This book was released on 2020-12-02 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: The efficacy of immunotherapeutic approaches in the treatment of different cancer types is becoming increasingly obvious, and immunotherapies in cancer treatment have experienced a significant breakthrough in the last few years. Immunotherapy encompasses several diverse treatment approaches, each of which has a distinct mechanism of action, and all of which are designed to boost or restore immune function in some manner. Consequently, T cell activating immunotherapeutic approaches like immune checkpoint inhibition, chimeric antigen receptor T cells (CARs), or bi-specific T cell activating antibodies are becoming increasingly important treatment strategies in different solid tumor types as well as in hematological malignancies. T cell responses against malignant cells play a major role in maintaining remission and prolonging overall survival in patients after allogeneic stem cell transplantation and donor lymphocyte infusions (DLI) due to the graft-versus-leukemia effect. In acute myeloid leukemia (AML) after intensive chemotherapy, most patients achieve complete remission; however, the overall survival for all AML patients, especially in elderly patients, is still relatively low. Immunotherapeutic approaches for AML patients might be options to reduce the relapse rate and improve overall survival. This Special Issue will focus on immunotherapeutic approaches in AML in established therapies, like the allogeneic stem cell transplantation including new concepts improving the graft-versus-leukemia effect, but also on new efforts to improve immune responses like adoptive T cell transfer, immune checkpoint inhibition, bi-specific antibodies, and CAR-T-cell approaches.

Medicare's Future

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Author :
Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Medicare's Future by : United States. Congress. House. Committee on the Budget

Download or read book Medicare's Future written by United States. Congress. House. Committee on the Budget and published by . This book was released on 2012 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Calm Healing

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Publisher : North Atlantic Books
ISBN 13 : 9781556436260
Total Pages : 404 pages
Book Rating : 4.4/5 (362 download)

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Book Synopsis Calm Healing by : Robert Bruce Newman

Download or read book Calm Healing written by Robert Bruce Newman and published by North Atlantic Books. This book was released on 2006-12-12 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: With disease statistics rising and health-care costs soaring, Calm Healing is a timely book indeed. Written in an accessible style, the book shows readers how to take an active role in their health by developing their innate skills for healing themselves and others. Part I presents a history of mind-body medicine, describing meditation methods across cultures and meditation research in the United States. Part II creates a new model of the human body based on a synthesis of disciplines, including quantum physics and energy medicine. Part III describes a wide range of healing methods including the healing practice of humor, cardio-awareness, progressive neuromuscular release, awareness-based energy breathing, transformative compassionate breathing, childbirth applications, and methods for near-death care. This section concludes with an analysis of healing the present by healing the past. Part IV focuses on self-healing and the worldwide transformation made possible by the effective action of groups engaged in mind-body healing.

Federal Register

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Publisher :
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Federal Register by :

Download or read book Federal Register written by and published by . This book was released on 1995-08 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Implementation of the Food and Drug Administration Modernization Act of 1997

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Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Implementation of the Food and Drug Administration Modernization Act of 1997 by : United States. Congress. House. Committee on Commerce

Download or read book Implementation of the Food and Drug Administration Modernization Act of 1997 written by United States. Congress. House. Committee on Commerce and published by . This book was released on 1999 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Future of Higher Education

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470730625
Total Pages : 304 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis The Future of Higher Education by : Frank Newman

Download or read book The Future of Higher Education written by Frank Newman and published by John Wiley & Sons. This book was released on 2010-04-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful look at the risks inherent in the trend toward making higher education a market rather than a regulated public sector, The Future of Higher Education reveals the findings of an extensive four-year investigation into the major forces that are transforming our American system of higher education. The book explores the challenges of intensified competition among institutions, globalization of colleges and universities, the expansion of the new for-profit and virtual institutions, and the influence of technology on learning. This important resource offers college and university leaders and policy makers an analysis of the impact of these forces of change and includes suggestions for creating an effective higher education market as well as a call for a renewed focus on the public purposes of higher education.

Evil in Modern Myth and Ritual

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Publisher : Wipf and Stock Publishers
ISBN 13 : 1532686250
Total Pages : 204 pages
Book Rating : 4.5/5 (326 download)

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Book Synopsis Evil in Modern Myth and Ritual by : Richard Stivers

Download or read book Evil in Modern Myth and Ritual written by Richard Stivers and published by Wipf and Stock Publishers. This book was released on 2020-04-28 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richard Stivers' concern is with the social construction of evil, that is, with how modern societies, in a partly unconscious way, create evil as a category of the sacred and how symbols, myths, and rituals of evil are related to this. He is interested, moreover, in how modern societies provoke individuals to commit evil actions. This fascinating and stimulating book is the first attempt to work out in detail how the concepts of the sacred, symbol, myth, and ritual form a cultural configuration in modern technological societies, and not just in traditional societies.

Advances in Genetics

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Publisher : Academic Press
ISBN 13 : 0080923496
Total Pages : 160 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Advances in Genetics by :

Download or read book Advances in Genetics written by and published by Academic Press. This book was released on 2011-09-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

Tissue-specific vascular endothelial signals and vector targeting. Part A

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Author :
Publisher : Academic Press
ISBN 13 : 0123750105
Total Pages : 320 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Tissue-specific vascular endothelial signals and vector targeting. Part A by : Renata Pasqualini

Download or read book Tissue-specific vascular endothelial signals and vector targeting. Part A written by Renata Pasqualini and published by Academic Press. This book was released on 2009 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes imporatnt reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Provides contrasting roles of VEGF, giving researchers a better understanding of the underlying mechanisms of VEGF *Includes chapters that review research employing a variety of organisms, allowing researchers to compare and contrast *Focuses on material that translates basic research to real-life treatment applications, showing primary researchers how the basic science is being used in the clinical setting.

The Last Negroes at Harvard

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Publisher : Mariner Books
ISBN 13 : 1328879976
Total Pages : 321 pages
Book Rating : 4.3/5 (288 download)

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Book Synopsis The Last Negroes at Harvard by : Kent Garrett

Download or read book The Last Negroes at Harvard written by Kent Garrett and published by Mariner Books. This book was released on 2020 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold story of the Harvard class of '63, whose Black students fought to create their own identities on the cusp between integration and affirmative action. In the fall of 1959, Harvard recruited an unprecedented eighteen "Negro" boys as an early form of affirmative action. Four years later they would graduate as African Americans. Some fifty years later, one of these trailblazing Harvard grads, Kent Garrett, would begin to reconnect with his classmates and explore their vastly different backgrounds, lives, and what their time at Harvard meant. Garrett and his partner Jeanne Ellsworth recount how these eighteen youths broke new ground, with ramifications that extended far past the iconic Yard. By the time they were seniors, they would have demonstrated against national injustice and grappled with the racism of academia, had dinner with Malcolm X and fought alongside their African national classmates for the right to form a Black students' organization. Part memoir, part group portrait, and part narrative history of the intersection between the civil rights movement and higher education, this is the remarkable story of brilliant, singular boys whose identities were changed at and by Harvard, and who, in turn, changed Harvard.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999

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Author :
Publisher :
ISBN 13 :
Total Pages : 1416 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1998 with total page 1416 pages. Available in PDF, EPUB and Kindle. Book excerpt: