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The Use Of Machine Learning In Assessing Mammalian Pre Implantation Embryo Quality
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Book Synopsis An Atlas of Human Blastocysts by : Lucinda L. Veeck
Download or read book An Atlas of Human Blastocysts written by Lucinda L. Veeck and published by CRC Press. This book was released on 2003-03-28 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing information from the cutting edge of reproductive technology, this full-color atlas vividly illustrates the typical and atypical morphology of human blastocysts collected and cultured during the course of in vitro fertilization treatments. The narrative and the illustrations detail a variety of new reproductive technologies. All photographs are supported by detailed legends and a glossary of terms is included. This atlas is edited by two world-class embryologists both of whom work at the Center for Reproductive Medicine and Infertility at the Weill Medical College of Cornell University.
Book Synopsis Natural Biomarkers for Cellular Metabolism by : Vladimir V. Ghukasyan
Download or read book Natural Biomarkers for Cellular Metabolism written by Vladimir V. Ghukasyan and published by CRC Press. This book was released on 2014-09-26 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Lab to Clinical Settings—Advances in Quantitative, Noninvasive Optical Diagnostics Noninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of new therapeutic targets for drug discoveries. Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications delves into the current state of knowledge on intrinsic fluorescent biomarkers and highlights recent developments in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. Autofluorescent Biomarkers for Biomedical Diagnostics The book’s first section introduces the fundamentals of cellular energy metabolism as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods, including experimental design, calibration, pitfalls, and remedies of data acquisition and analysis. The last two sections highlight advances in biomedical and biochemical applications, such as monitoring stem cell differentiation in engineered tissues and diagnosing cancer and ophthalmic diseases quantitatively and noninvasively. Tailored to Interdisciplinary Researchers Covering cell biology, imaging techniques, and clinical diagnostics, this book provides readers with a complete guide to studying cellular/tissue metabolism under healthy, diseased, and environment-induced stress conditions using natural biomarkers. The book is designed for graduate and advanced undergraduate students, biophysics instructors, medical researchers, and those in pharmaceutical R&D.
Book Synopsis Preimplantation Embryo Development by : Barry D. Bavister
Download or read book Preimplantation Embryo Development written by Barry D. Bavister and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the Proceedings of the Serono Symposium on Pre implantation Embryo Development, held in Newton, Massachusetts, in 1991. The idea for the symposium grew out of the 1989 Serono Symposium on Fertilization in Mammals* at which preimplantation development was the predominant suggestion for a follow-up topic. This was indeed a timely subject in view of the recent resurgence of interest in this funda mental phase of embryogenesis and its relevance to basic research and applied fertility studies in humans, food-producing animals, and endangered species. The symposium brought together speakers from a broad range of disciplines in order to focus on key regulatory mechanisms in embryo development, using a wide variety of animal models, and on representative topics in human preimplantation embryogenesis. The culmination of preimplantation development is a blastocyst con taining the first differentiated embryonic tissues and capable of initiating and sustaining pregnancy. The central objective of the symposium was to throw light on the regulation of cellular and molecular events underlying blastocyst formation. It was particularly appropriate that the date of the symposium marked the 20th anniversary of the publication of the classic volume Biology of the Blastocyst, the proceedings of an international workshop held in 1970. This book, which summarized most of the information then available on this topic in mammals, was edited by the pioneer in blastocyst research, Dr. Richard B1andau, who was the guest speaker at the symposium.
Author :Jonathan van Blerkom Publisher :Springer Science & Business Media ISBN 13 :9781402075513 Total Pages :652 pages Book Rating :4.0/5 (755 download)
Book Synopsis Essential IVF by : Jonathan van Blerkom
Download or read book Essential IVF written by Jonathan van Blerkom and published by Springer Science & Business Media. This book was released on 2004 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intent of Essential IVF is to present current issues in clinical IVF that encompass the varied activities of those engaged in this field. By integrating clinical, basic research and laboratory-related aspects of human reproduction, readers with diverse interests should obtain a more complete understanding of the impact, importance and relevance of each in the progress of infertility treatment and an appreciation of whether emerging technologies will or should contribute to this progress in the near future. The topics selected for this volume include research that has begun to explain the origins of different follicular, gamete, embryo and uterine competence as well as specific laboratory procedures and protocols that may have important clinical implications for the generation of developmentally viable embryos. Comprehensive reviews and discussions of past and contemporary studies in clinically-oriented chapters provide a biological and outcome-based context in which current practices and protocols in human IVF may need to be reconsidered.
Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council
Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Book Synopsis Textbook of Clinical Embryology by : Kevin Coward
Download or read book Textbook of Clinical Embryology written by Kevin Coward and published by Cambridge University Press. This book was released on 2013-10-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
Book Synopsis ART and the Human Blastocyst by : David K. Gardner
Download or read book ART and the Human Blastocyst written by David K. Gardner and published by Springer Science & Business Media. This book was released on 2001 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued debate regarding the stage at which the human embryo conceived in the laboratory should be placed in the mother, combined with recent developments in culture media formulations, have brought the role of the human blastocyst in ART back into the spotlight. ART and the Human Blastocyst presents the proceedings of the International Symposium on ART and the Human Blastocyst held from March 30- April 2, 2000 in Dana Point, California. This book brings to the forefront the main issues raised with the transfer of embryos at the blastocyst stage, including the reduction of high order multiple gestations and the role of the blastocyst culture and transfer in facilitating successful single embryo transfer. Sections include gamete quality and pregnancy outcome, physiology of the embryo, blastocyst development in culture, blastocyst transfer and fate, and implantation. More than 40 illustrations and 25 tables complement the text.
Book Synopsis Patient-Centered Assisted Reproduction by : Alice D. Domar
Download or read book Patient-Centered Assisted Reproduction written by Alice D. Domar and published by Cambridge University Press. This book was released on 2020-03-19 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for reproduction professionals wishing to understand patient-centered advanced technologies now and in the future.
Book Synopsis Textbook of Assisted Reproductive Techniques by : David K. Gardner
Download or read book Textbook of Assisted Reproductive Techniques written by David K. Gardner and published by CRC Press. This book was released on 2023-12-13 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on laboratory topics, including KPIs for the IVF laboratory, Quality control in the cloud, Artificial Intelligence, AI in gamete and embryo selection, Demystifying vitrification, Microfluidics, Gene editing, Disaster management, and Early human embryo development revealed by static imaging. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Book Synopsis In Vitro Fertilization and Embryo Transfer by : Don P. Wolf
Download or read book In Vitro Fertilization and Embryo Transfer written by Don P. Wolf and published by Springer Science & Business Media. This book was released on 1988-06-30 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. "The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of culture conditions and requirements necessary for in vitro oocyte maturation, fertilization and development in model mammalian systems including nonhuman primates have contributed greatly to our understanding of the mammalian fertilization process. Wolf, Kopf and Gerrity have enjoyed substantial interaction with clinicians in Departments of Obstetrics and Gynecology and have been directly involved with successful IVF programs. Both Wolf and Kopf have served as research scientists in the Division of Reproductive Biology at the University of Pennsylvania, which, for more than 22 years, has fostered co-mingling of clinically oriented and basic science faculty. It is through such interaction, which clearly exists at many institutions including the University of Wisconsin, that the process of technology transfer is best served. Without an exquisitely coordinated laboratory, there can be no consistent success in human in vitro fertilization. Quality control is pivotal, but close collaboration between the laboratory and the clinic is also essential as information is shared and correlated.
Book Synopsis Unsupervised Learning by : Geoffrey Hinton
Download or read book Unsupervised Learning written by Geoffrey Hinton and published by MIT Press. This book was released on 1999-05-24 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its founding in 1989 by Terrence Sejnowski, Neural Computation has become the leading journal in the field. Foundations of Neural Computation collects, by topic, the most significant papers that have appeared in the journal over the past nine years. This volume of Foundations of Neural Computation, on unsupervised learning algorithms, focuses on neural network learning algorithms that do not require an explicit teacher. The goal of unsupervised learning is to extract an efficient internal representation of the statistical structure implicit in the inputs. These algorithms provide insights into the development of the cerebral cortex and implicit learning in humans. They are also of interest to engineers working in areas such as computer vision and speech recognition who seek efficient representations of raw input data.
Book Synopsis Computational Intelligence by : David I. Poole
Download or read book Computational Intelligence written by David I. Poole and published by Oxford University Press on Demand. This book was released on 1998 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an integrated introduction to artificial intelligence. Develops AI representation schemes and describes their uses for diverse applications, from autonomous robots to diagnostic assistants to infobots. DLC: Artificial intelligence.
Book Synopsis Apoptosis and Senescence in Vertebrate Development by : Wolfgang Knabe
Download or read book Apoptosis and Senescence in Vertebrate Development written by Wolfgang Knabe and published by Frontiers Media SA. This book was released on 2022-02-14 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Human Gametes and Preimplantation Embryos by : David K. Gardner
Download or read book Human Gametes and Preimplantation Embryos written by David K. Gardner and published by Springer Science & Business Media. This book was released on 2013-05-27 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
Download or read book Embryo Cleavage written by Bin Wu and published by BoD – Books on Demand. This book was released on 2017-09-06 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embryo cleavage experiences a series of critical events and remarkable epigenetic modifications, especially morphological change and gene expression. The development of current assisted reproductive technology has created some new observations and novel discoveries in cleavage embryos. This book updates some new technologies and methods on the study of cleavage embryos to select high-quality embryos for transfer and improve embryo implantation and pregnancy. Major contents include embryo cleavage morphokinetics based on time-lapse imaging, gene expression of cleavage embryo and noninvasive assessment, and improving embryo cleavage technology. Thus, this book will greatly add new information for embryologists to select good-quality embryos for transfer to improve human embryo transfer pregnancy rate.
Book Synopsis Manual of Embryo Culture in Human Assisted Reproduction by : Kersti Lundin
Download or read book Manual of Embryo Culture in Human Assisted Reproduction written by Kersti Lundin and published by Cambridge University Press. This book was released on 2021-05-06 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides practical guidance for the optimal organization and management of an IVF laboratory for successful embryo culture.
Book Synopsis Molecular Imaging: Computer Reconstruction and Practice by : Yves Lemoigne
Download or read book Molecular Imaging: Computer Reconstruction and Practice written by Yves Lemoigne and published by Springer Science & Business Media. This book was released on 2008-09-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports the majority of lectures given during the NATO Advanced Study Institute ASI-982440, which was held at the European Scienti?c Institute of Archamps (ESI, Archamps – France) from November 9 to November 21, 2006. The ASI course was structured in two parts, the ?rst was dedicated to individual imaging techniques while the second is the object of this volume and focused on data modelling and processing and on image archiving and distribution. Courses devoted to nuclear medicine and digital imaging techniques are collected in a c- plementary volume of NATO Science Series entitled “Physics for Medical Imaging Applications” (ISBN 978-1-4020-5650-5). Every year in autumn ESI organises the European School of Medical Physics, which covers a large spectrum of topics ranging from Medical Imaging to Rad- therapy, over a period of ?ve weeks. Thanks to the Cooperative Science and Te- nology sub-programme of the NATO Science Division, weeks two and three were replaced this year by the ASI course dedicated to “Molecular Imaging from Physical Principles to Computer Reconstruction and Practice”. This allowed the participation ofexpertsandstudentsfrom20differentcountries,withdiverseculturalbackground and professional experience (Africa, America, Asia, and Europe). A further positive outcome of NATO ASI participation is the publication of this book, which contains the lectures series contributed by speakers during the second week of the ASI.
