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Author : Geoffrey Jones
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (55 download)
Download or read book The Statistics of Multiple Immunoassay written by Geoffrey Jones and published by . This book was released on 1996 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : N. W. Galwey
Publisher : John Wiley & Sons
ISBN 13 : 047003596X
Total Pages : 379 pages
Book Rating : 4.4/5 (7 download)
Download or read book Introduction to Mixed Modelling written by N. W. Galwey and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mixed modelling is one of the most promising and exciting areas ofstatistical analysis, enabling more powerful interpretation of datathrough the recognition of random effects. However, many perceivemixed modelling as an intimidating and specialized technique. Thisbook introduces mixed modelling analysis in a simple andstraightforward way, allowing the reader to apply the techniqueconfidently in a wide range of situations. Introduction to Mixed Modelling shows that mixedmodelling is a natural extension of the more familiar statisticalmethods of regression analysis and analysis of variance. In doingso, it provides the ideal introduction to this importantstatistical technique for those engaged in the statistical analysisof data. This essential book: Demonstrates the power of mixed modelling in a wide range ofdisciplines, including industrial research, social sciences,genetics, clinical research, ecology and agriculturalresearch. Illustrates how the capabilities of regression analysis can becombined with those of ANOVA by the specification of a mixedmodel. Introduces the criterion of Restricted Maximum Likelihood(REML) for the fitting of a mixed model to data. Presents the application of mixed model analysis to a widerange of situations and explains how to obtain and interpret BestLinear Unbiased Predictors (BLUPs). Features a supplementary website containing solutions toexercises, further examples, and links to the computer softwaresystems GenStat and R. This book provides a comprehensive introduction to mixedmodelling, ideal for final year undergraduate students,postgraduate students and professional researchers alike. Readerswill come from a wide range of scientific disciplines includingstatistics, biology, bioinformatics, medicine, agriculture,engineering, economics, and social sciences.
Author : Paul P. Glasziou
Publisher : John Wiley & Sons
ISBN 13 : 0470695617
Total Pages : 376 pages
Book Rating : 4.4/5 (76 download)
Download or read book Evidence-Based Medical Monitoring written by Paul P. Glasziou and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising. This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.
Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 924154788X
Total Pages : 73 pages
Book Rating : 4.2/5 (415 download)
Download or read book Screening Donated Blood for Transfusion-transmissible Infections written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Blood transfusion is a life-saving intervention that has an essential role in patient management within health care systems. All Member States of the World Health Organization (WHO) endorsed World Health Assembly resolutions WHA28.72 (1) in 1975 and WHA58.13 (2) in 2005. These commit them to the provision of adequate supplies of safe blood and blood products that are accessible to all patients who require transfusion either to save their lives or promote their continuing or improving health." --Preface.
Author : I. Weeks
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.:/5 (318 download)
Download or read book Chemiluminescence Immunoassay written by I. Weeks and published by . This book was released on 1992 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemiluminescence immunoassay is now established as one of the best alternatives to conventional radioimmunoassay for the quantitation of low concentrations of analytes in complex samples. During the last two decades the technology has evolved into analytical procedures whose performance far exceeds that of immunoassays based on the use of radioactive labels. Without the constraints of radioactivity, the scope of this type of analytical procedure has widened beyond the confines of the specialist clinical chemistry laboratory to other disciplines such as microbiology, veterinary medicine, agriculture, food and environmental testing. This is the first work to present the topic as a subject in its own right. In order to provide a complete picture of the subject, overviews are presented of the individual areas of chemiluminescence and immunoassay with particular emphasis on the requirements for interfacing chemiluminescent and immunochemical reactions. The possible ways of configuring chemiluminescence immunoassays are described. State-of-the-art chemiluminescence immunoassay systems are covered in detail together with those systems which are commercially available. The book is aimed at researchers and routine laboratory staff in the life sciences who wish to make use of this high-performance analytical technique and also at those interested in industrial applications of the technology in the food, agricultural and environmental sciences.
Author : Sweta Rani
Publisher : Springer Nature
ISBN 13 : 1071628232
Total Pages : 258 pages
Book Rating : 4.0/5 (716 download)
Download or read book MicroRNA Profiling written by Sweta Rani and published by Springer Nature. This book was released on 2022-11-28 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of exosomes, serum, plasma specimens, and software tools. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA Profiling: Methods and Protocols, Second Edition aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.
Author : Lanju Zhang
Publisher : Springer
ISBN 13 : 3319235583
Total Pages : 705 pages
Book Rating : 4.3/5 (192 download)
Download or read book Nonclinical Statistics for Pharmaceutical and Biotechnology Industries written by Lanju Zhang and published by Springer. This book was released on 2016-01-13 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods important to the nonclinical science areas within the pharmaceutical and biotechnology industries. Specifically the Discovery and Translational sciences, the Safety/Toxiology sciences, and the Chemistry, Manufacturing and Controls sciences. Drug discovery and development is a long and costly process. Most decisions in the drug development process are made with incomplete information. The data is rife with uncertainties and hence risky by nature. This is therefore the purview of Statistics. As such, this book aims to introduce readers to important statistical thinking and its application in these nonclinical areas. The chapters provide as appropriate, a scientific background to the topic, relevant regulatory guidance, current statistical practice, and further research directions.
Author : Haian Fu
Publisher : Cambridge University Press
ISBN 13 : 1107377587
Total Pages : 359 pages
Book Rating : 4.1/5 (73 download)
Download or read book Chemical Genomics written by Haian Fu and published by Cambridge University Press. This book was released on 2012-02-13 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of the basic principles of chemical biology and chemical genomics. This is followed by a technical section that describes the sources of small-molecule chemicals; the basics of high-throughput screening technologies; and various bioassays for biochemical-, cellular- and organism-based screens. The final chapters connect the chemical genomics field with personalized medicine and the druggable genome for future discovery of new therapeutics. This book will be valuable to researchers, professionals and graduate students in many fields, including biology, biomedicine and chemistry.
Author : Robert Zivadinov
Publisher : Nova Publishers
ISBN 13 : 9781594541605
Total Pages : 220 pages
Book Rating : 4.5/5 (416 download)
Download or read book Brain and Spinal Cord Atrophy in Multiple Sclerosis written by Robert Zivadinov and published by Nova Publishers. This book was released on 2005 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for general neurologists as well as specialists in multiple sclerosis (MS) and imaging, this book provides comprehensive discussion of central nervous system (CNS) atrophy involving the brain and spinal cord, and both the chapter authors and topics have been selected to provide state-of-the-art reviews. Key issues covered in the book include pathogenesis and its mechanisms, technical aspects of MRI measurement, the relationship between CNS atrophy and other MRI metrics, clinical relevance, the association with neurobehavioral and genetic-immunologic components of MS, and the effects of disease-modifying therapies on tissue atrophy. Pros and cons of different technical approaches are discussed critically. Special attention is devoted to CNS atrophy as a clinically relevant biologic marker of the MS disease process.
Author : Jeanette M. van Emon
Publisher : CRC Press
ISBN 13 : 1420020692
Total Pages : 536 pages
Book Rating : 4.4/5 (2 download)
Download or read book Immunoassay and Other Bioanalytical Techniques written by Jeanette M. van Emon and published by CRC Press. This book was released on 2016-04-19 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contribut
Author : Richard O'Kennedy
Publisher : CRC Press
ISBN 13 : 1351797344
Total Pages : 362 pages
Book Rating : 4.3/5 (517 download)
Download or read book Immunoassays written by Richard O'Kennedy and published by CRC Press. This book was released on 2017-06-26 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept behind this book is to provide a detailed and practical overview of the development and use of immunoassays in many different areas. Immunoassays are analytical tests that utilise antibodies to measure the amount, activity or identity of an analyte. This book is designed to provide a critical and helpful insight into the subject and to give the user practical information that may be of assistance in assay format selection, antibody generation/selection and choice of appropriate detection strategies. It is comprised of 13 chapters written by highly experienced researchers in the fields of antibody-based research, immunoassay development, assay validation, diagnostics and microfluidics. Beginning with a comprehensive survey of antibodies, immunoassay formats and signalling systems, the book elucidates key topics related to the development of an ideal antibody-based sensor, focuses on the important topic of surface modification, explores key parameters in the immobilisation of antibodies onto solid surfaces, discusses the move to ‘lab-on-a-chip’-based devices and investigates the key parameters necessary for their development. Three of the chapters are dedicated to the areas of clinical diagnostics, infectious disease monitoring and food security, where immunoassay-based applications have become highly valuable tools. The future of immunoassays, including next-generation immunoassays, electrochemical-immunoassays and ‘lab-on-a-chip’-based systems, is also discussed. The book also covers the use of optical detection systems (with a focus on surface plasmon resonance) in immunoassays, provides a compilation of important, routinely used immunoassay protocols and addresses problems that may be encountered during assay development.
Author :
Publisher :
ISBN 13 :
Total Pages : 1488 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sandeep K. Vashist
Publisher : Academic Press
ISBN 13 : 012811794X
Total Pages : 498 pages
Book Rating : 4.1/5 (281 download)
Download or read book Handbook of Immunoassay Technologies written by Sandeep K. Vashist and published by Academic Press. This book was released on 2018-01-02 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. - Provides a valuable increase of understanding of cellular and biomedical functions - Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings - Discusses all multifarious aspects of immunoassays - Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications - Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays
Author : Harvey Motulsky
Publisher : Oxford University Press
ISBN 13 : 9780198038344
Total Pages : 352 pages
Book Rating : 4.0/5 (383 download)
Download or read book Fitting Models to Biological Data Using Linear and Nonlinear Regression written by Harvey Motulsky and published by Oxford University Press. This book was released on 2004-05-27 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most biologists use nonlinear regression more than any other statistical technique, but there are very few places to learn about curve-fitting. This book, by the author of the very successful Intuitive Biostatistics, addresses this relatively focused need of an extraordinarily broad range of scientists.
Author : William Clarke
Publisher : Academic Press
ISBN 13 : 0128158336
Total Pages : 1070 pages
Book Rating : 4.1/5 (281 download)
Download or read book Contemporary Practice in Clinical Chemistry written by William Clarke and published by Academic Press. This book was released on 2020-06-11 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. - Includes enhanced illustration and new and revised color figures - Provides improved self-assessment questions and end-of-chapter assessment questions
Author : Richard B. M. Schasfoort
Publisher : Royal Society of Chemistry
ISBN 13 : 1782627308
Total Pages : 555 pages
Book Rating : 4.7/5 (826 download)
Download or read book Handbook of Surface Plasmon Resonance written by Richard B. M. Schasfoort and published by Royal Society of Chemistry. This book was released on 2017-05-30 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.
Author : Sergey I. Bozhevolnyi
Publisher : Springer
ISBN 13 : 3319458205
Total Pages : 338 pages
Book Rating : 4.3/5 (194 download)
Download or read book Quantum Plasmonics written by Sergey I. Bozhevolnyi and published by Springer. This book was released on 2016-11-26 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest results of quantum properties of light in the nanostructured environment supporting surface plasmons, including waveguide quantum electrodynamics, quantum emitters, strong-coupling phenomena and lasing in plasmonic structures. Different approaches are described for controlling the emission and propagation of light with extreme light confinement and field enhancement provided by surface plasmons. Recent progress is reviewed in both experimental and theoretical investigations within quantum plasmonics, elucidating the fundamental physical phenomena involved and discussing the realization of quantum-controlled devices, including single-photon sources, transistors and ultra-compact circuitry at the nanoscale.
