The Science Of Autophagy

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Autophagy: Biology and Diseases

Author : Zheng-Hong Qin
Publisher : Springer Nature
ISBN 13 : 9811506027
Total Pages : 727 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Autophagy: Biology and Diseases by : Zheng-Hong Qin

Download or read book Autophagy: Biology and Diseases written by Zheng-Hong Qin and published by Springer Nature. This book was released on 2019-11-27 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.

Autophagy

Author : Thomas Hawthorn
Publisher : scott m ecommerce
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4./5 ( download)

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Book Synopsis Autophagy by : Thomas Hawthorn

Download or read book Autophagy written by Thomas Hawthorn and published by scott m ecommerce. This book was released on 2019-06-24 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how a one day starvation secret won the nobel prize. And how you can use it to lose weight and promote long-term health. In 2016, Yoshinori Ohsumi won the Nobel Prize for his research on Autophagy. Now, not only does autophagy have lifechanging weight loss benefits… It may help treat cancer and neurodegenerative diseases like Alzheimer’s. Why has this unique type of fasting only become established in the past couple of years? It’s simple, the fat cats of our food industry establishment have billions riding on the outdated “3 square meals a day” lifestyle. And not only is this typical American lifestyle outdated, it’s downright dangerous! However, there is another way. And inside this breakthrough book you’ll discover: How to lose weight faster while intermittent fasting IBS pain? You can blame this common food 5 superfoods you can find at your local supermarket How inflamed is your body right now? Exactly what to ask your doctor to find out the truth. How to increase autophagy without fasting for several days in a row 7 best foods for nurturing gut health Eat this “forgotten food” to reverse plaque build up in your arteries How to properly do a water fast without feeling weak or getting hungry. A handful of this food cuts risk of heart disease by 24% 1 in 4 supplements failed quality tests at a leading independent lab. Discover which ones to throw out How to lose weight without working out every day 3 beginner mistakes which actually prevent autophagy, and how to avoid them Do you get autophagy during 16/8 fasting? The surprising truth …and much, much more. Plus countless other health secrets… Including this “miracle beverage” which researchers at the University of Minnesota found lowered diabetes risk by 33%... drinking this also boosts the effectiveness of your fast… plus one drink to avoid which sneakily breaks your fast You’ll also discover How to avoid starvation mode while fasting The raw truth about extended water fasting Is too much autophagy bad? Get the answer from the world’s leading expert Why do dogs who eat 1 meal a day live 20% longer than dogs who eat 3 meals a day? The 3 benefits of autophagy you probably didn’t know about Autophagy success stories – how one obese Mom lost 90lbs in less than 6 months and cured her diabetes All written in plain English. So you don’t need a medical degree to understand and apply what’s inside. This is not just a diet fad. This is a long-term gamechanger in the health and longevity space. Here’s the deal. The traditional “calories in, calories out” weight loss method no longer works. And restrictive low-fat or vegan diets often leave you hungry and irritable. However, when you combine the keto diet with a 2016 Nobel Prize winning breakthrough known as autophagy – you get the keto diet on steroids So take control of your life and show your friends and family that there is a simple way to lose weight and be happy – scroll up and click “add to cart”

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Author : M. A. Hayat
Publisher : Academic Press
ISBN 13 : 0128094273
Total Pages : 430 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat

Download or read book Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available

The Science Of Autophagy

Author : Douglas Tieman
Publisher :
ISBN 13 : 9781646961115
Total Pages : 220 pages
Book Rating : 4.9/5 (611 download)

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Book Synopsis The Science Of Autophagy by : Douglas Tieman

Download or read book The Science Of Autophagy written by Douglas Tieman and published by . This book was released on 2019-11-26 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you also heard of this trendy new term "Autophagy" but just cannot really get behind it? Are you looking for a scientifically accurate, but easy to understand guide to use the new concept to your advantage? Or are you simply interested in a healthy lifestyle, a sustainable diet form or detoxification of your body? If you answered yes to at least one of the questions above, this guide is specifically written for you. Currently, there are not many Autophagy-books out there and the ones who often lack scientific accuracy, the density of information or are simply too confusing and hard to understand for a layman. But what exactly is Autophagy, you might ask? Great question! Autophagos is greek and stands for "self-devouring". It is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Yoshinori Ohsumi won the Nobel Prize for his discoveries into the mechanisms of Autophagy. These have led to a better understanding of diseases such as Parkinson's and dementia. In this guide you'll discover: The 4 little- known benefits of Autophagy to extend your life and protect your health (Even if you already workout and eat quite healthy!) What exactly is Autophagy step by step and how to regulate it? Why the importance of Autophagy has been underestimated for years - with dramatic consequences! The 7 magical ways to activate the hidden power - in a natural and healthy way The biggest myth busted: a comprehensive glossary to understand all the relevant vocabulary, mechanisms and complex relationships that concern Autophagy Does Autophagy have any downsides? And if yes, what are the best ways to deal with them effectively? The absolute worst 3 things you might be doing to hinder Autophagy (avoid these mistakes at all costs if you want to reap the full benefits!) ...and much, much more! By relying on the latest scientific research from international experts, this guide is able to identify the exact dietary and non- dietary actions to induce Autophagy and jumpstart your health, well-being, weight loss and much more. So if you want to finally take advantage of the revolutionary new process to boost health, lose weight and much more, click "Add to Cart" now!

Autophagy: Biology and Diseases

Author : Zhiping Xie
Publisher : Springer Nature
ISBN 13 : 9811628300
Total Pages : 453 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Autophagy: Biology and Diseases by : Zhiping Xie

Download or read book Autophagy: Biology and Diseases written by Zhiping Xie and published by Springer Nature. This book was released on 2021-07-14 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools, strategies, and model systems in current autophagy research, including cell and animal models, detection and manipulation methods, as well as screening, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.

Glow15

Author : Naomi Whittel
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 1328897672
Total Pages : 327 pages
Book Rating : 4.3/5 (288 download)

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Book Synopsis Glow15 by : Naomi Whittel

Download or read book Glow15 written by Naomi Whittel and published by Houghton Mifflin Harcourt. This book was released on 2018 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on Nobel Prize-winning research, an easy-to-follow lifestyle plan for losing weight, looking younger, and feeling energized.

Autophagy

Author : Thomas Hawthorn
Publisher :
ISBN 13 : 9781913470272
Total Pages : 130 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Autophagy by : Thomas Hawthorn

Download or read book Autophagy written by Thomas Hawthorn and published by . This book was released on 2019-11-24 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: AMS: Discover how a one day starvation secret won the nobel prize. And how you can use it to lose weight and promote long-term health. Autophagy for Beginners: How to Combine Intermittent Fasting and Nobel Prize Winning Science for Rapid Weight Loss, Reducing Inflammation and Promoting Long-Term Health In 2016, Yoshinori Ohsumi won the Nobel Prize for his research on Autophagy. Not only does autophagy have lifechanging weight loss benefits... It may help treat cancer and neurodegenerative diseases like Alzheimer's. Why has this unique type of fasting only become established in the past couple of years? It's simple, the fat cats of our food industry establishment have billions riding on the outdated "3 square meals a day" lifestyle. And not only is this typical American lifestyle outdated, it's downright dangerous. However, there is another way. And inside this breakthrough book you'll discover: - How to lose weight faster while intermittent fasting - IBS pain? You can blame this common food - 5 superfoods you can find at your local supermarket - How inflamed is your body right now? Exactly what to ask your doctor to find out the truth. - How to increase autophagy without fasting for several days in a row - 7 best foods for nurturing gut health - Eat this "forgotten food" to reverse plaque build up in your arteries - How to properly do a water fast without feeling weak or getting hungry. - A handful of this food cuts risk of heart disease by 24% - 1 in 4 supplements failed quality tests at a leading independent lab. Discover which ones to throw out (acid test) - How to lose weight without working out every day - 3 beginner mistakes which actually prevent autophagy, and how to avoid them - Do you get autophagy during 16/8 fasting? The surprising truth ...and much, much more. Plus countless other health secrets... Including this "miracle beverage" which researchers at the University of Minnesota found lowered diabetes risk by 33%... drinking this also boosts the effectiveness of your fast... plus one drink to avoid which sneakily breaks your fast You'll also discover - How to avoid starvation mode while fasting - The raw truth about extended water fasting - Is too much autophagy bad? Get the answer from the world's leading expert - Why do dogs who eat 1 meal a day live 20% longer than dogs who eat 3 meals a day? - The 3 benefits of autophagy you probably didn't know about - Autophagy success stories - how one obese Mom lost 90lbs in less than 6 months and cured her diabetes All written in plain English. So you don't need a medical degree to understand and apply what's inside. This is not just a diet fad. This is a long-term gamechanger in the health and longevity space. Here's the deal. The traditional "calories in, calories out" weight loss method no longer works. And restrictive low-fat or vegan diets often leave you hungry and irritable. However, when you combine the keto diet with a 2016 Nobel Prize winning breakthrough known as autophagy - you get the keto diet on steroids So take control of your life and show your friends and family that there is a simple way to lose weight and be happy - scroll up and click "add to cart"

Metabolic Autophagy

Author : Siim Land
Publisher : Metabolic Autophagy Diet
ISBN 13 : 9781790686391
Total Pages : 534 pages
Book Rating : 4.6/5 (863 download)

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Book Synopsis Metabolic Autophagy by : Siim Land

Download or read book Metabolic Autophagy written by Siim Land and published by Metabolic Autophagy Diet. This book was released on 2019-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermittent Fasting for Longevity and Performance Your cells are constantly monitoring the nutrient status of the cells to determine whether or not to conserve energy or to promote growth. **One of the few known ways of increasing lifespan in almost all species is caloric restriction and energy deprivation.** This triggers many metabolic pathways and processes that make the organism more adaptable to environmental stressors and thus live longer. **The metabolism has two sub-categories or sub-processes called anabolism and catabolism. ** * Anabolism, meaning 'upward' in Greek, describes the synthesis of biological molecules to build up new physical matter in the body. * Catabolism, meaning 'downward' in Greek, describes the breaking down of biological molecules to release energy. This can apply to the breakdown of bodily tissue as well as the digestion of food that then gets assimilated into the body through anabolic processes. In addition to 'Metabolic', you can also find another word in the title - 'Autophagy', which translates from Ancient Greek into 'self-devouring' or 'eating of self'. This is central to the main practice of this book. By maintaining a balance between anabolism and catabolism, you can effectively extend your lifespan. The process of autophagy entails your healthy cells devouring the old, worn-out, weak ones and converting them back into energy. It's literally your body eating itself and using that to maintain homeostasis. There are many longevity-boosting benefits to this as illustrated in virtually all other species. This book is a collection of guidelines about the principles of the anabolic-catabolic cycles in regards to nutrition and exercise. It's definitely not a panacea - a solution or remedy for all conditions and circumstances. Instead, it's a very specific protocol that's not supposed to apply for all situations. **Metabolic Autophagy will teach you:** * What increases lifespan in humans and other species * Why there's so much disease and obesity in society * How to promote health and longevity with intermittent fasting * What is Autophagy and how it works * How to age slower and be vigorous throughout your life * Which foods make you live longer and build muscle * How the nutrient regulators of mTOR, AMPK, sirtuins, FOXO proteins, hormesis and others affect longevity * What are circadian rhythms and how they affect your health * Metabolic Autophagy Foods list and their anabolic-catabolic score * Supplements that support muscle growth and longevity * Many extras and bonuses in regards to food and exerciseSiim Land is a best-selling author, anthropologist, entrepreneur, high-performance coach and a biohacker who writes about optimizing health and human performance.This book incorporates daily lifestyle and dietary practices that help to cross the chasm between longevity and high performance.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Author : M. A. Hayat
Publisher : Academic Press
ISBN 13 : 0128121475
Total Pages : 622 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat

Autophagy in Health and Disease

Author : Roberta A. Gottlieb
Publisher : Academic Press
ISBN 13 : 0123851025
Total Pages : 240 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Autophagy in Health and Disease by : Roberta A. Gottlieb

Download or read book Autophagy in Health and Disease written by Roberta A. Gottlieb and published by Academic Press. This book was released on 2012-12-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes Features an accompanying website with figures and tables

Autophagy and Cancer

Author : Hong-Gang Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1461465613
Total Pages : 267 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Autophagy and Cancer by : Hong-Gang Wang

Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it.

Autophagy

Author : Daniel Klionsky
Publisher : CRC Press
ISBN 13 : 1498713270
Total Pages : 327 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Autophagy by : Daniel Klionsky

Download or read book Autophagy written by Daniel Klionsky and published by CRC Press. This book was released on 2003-12-15 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen

Autophagy for Beginners

Author : Jason Michaels and Thomas Hawthorn
Publisher : scott m ecommerce
ISBN 13 :
Total Pages : 273 pages
Book Rating : 4./5 ( download)

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Book Synopsis Autophagy for Beginners by : Jason Michaels and Thomas Hawthorn

Download or read book Autophagy for Beginners written by Jason Michaels and Thomas Hawthorn and published by scott m ecommerce. This book was released on 2019-06-27 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobel Prize Winning Secret Reveals How to Lose Weight & Extend Your Life… Fact: A study in Science Direct found that Autophagy induced fasting prevents obesity and age-related defects Fact: A study in Kidney International found that higher protein diets do not cause kidney failure Fact: Patients on the keto diet lost weight faster than those eating a higher carb diet. While also experiencing improved recovery and skin conditions Fact: A study in Pediatrics showed that children with epilepsy on the keto diet suffered 90% less seizures than before they started If you’re struggling to lose weight, even if you’ve tried every diet under the sun. This book is for you. Because you can lose weight while feeling full and satisfied… without exercising 3 hours+ a day! In this breakthrough book you’ll discover: How a one day starvation secret won the nobel prize IBS pain? You can blame this common food (artificially sweetened food) 5 superfoods you can find at your local supermarket (organ meats, kale, eggs, salmon, shiitake mushrooms) How inflamed is your body right now? Exactly what to ask your doctor to find out the truth. If you’re still fat after intermittent fasting – here’s why How to increase autophagy without fasting for several days in a row 7 best foods for nurturing gut health Eat this “forgotten food” to reverse plaque build up in your arteries (beef liver) How to properly do a water fast without feeling weak or getting hungry. A handful of this food cuts risk of heart disease by 24% (peanuts) 1 in 4 supplements failed quality tests at a leading independent lab. Discover which ones to throw out (acid test) How to lose weight without working out every day 3 beginner mistakes which actually prevent autophagy, and how to avoid them Do you get autophagy during 16/8 fasting? The surprising truth How to protect yourself against this deadly poison (EMF) Researches at the University of Minnesota found that drinking this first thing in the morning lowered diabetes risk by up to 33% (coffee) What to drink to boost the effectiveness of your fast. And one drink to avoid which sneakily breaks your fast Should you take a multivitamin while fasting? How to avoid starvation mode while fasting The raw truth about extended water fasting Is too much autophagy bad? Get the answer from the world’s leading expert (dr. Mercola) Why do dogs who eat 1 meal a day live 20% longer than dogs who eat 3 meals a day? The 3 benefits of autophagy you probably didn’t know about) Autophagy success stories – how one obese Mom lost 90lbs in less than 6 months and cured her diabetes …and much, much more. Plus 2 bonus books on keto meal prep and keto friendly meals at America’s favorite restaurants All written in plain English. So, you don’t need a medical degree to understand and apply what’s inside. This is not just a diet fad. This is a long-term gamechanger in the health and longevity space. Take control of your life and show your friends and family that there is a simple way to lose weight and be happy – scroll up and add to cart P.S. People who say the keto diet is unhealthy are usually promoting the “Regular American Diet”, the same diet which has lead to… 40% of Americans being classified as obese. 1 in 3 now suffering from high blood pressure. 1 in 10 suffering from diabetes. The “normal” way you’ve been told to eat is not healthy. Change your life and get your copy today.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Author : M. A. Hayat
Publisher : Academic Press
ISBN 13 : 0124055346
Total Pages : 432 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat

Autophagy in tumor and tumor microenvironment

Author : Sujit Kumar Bhutia
Publisher : Springer Nature
ISBN 13 : 9811569304
Total Pages : 284 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Autophagy in tumor and tumor microenvironment by : Sujit Kumar Bhutia

Download or read book Autophagy in tumor and tumor microenvironment written by Sujit Kumar Bhutia and published by Springer Nature. This book was released on 2020-10-24 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.

Autophagy of the Nervous System

Author : Zhenyu Yue
Publisher : World Scientific
ISBN 13 : 9814350443
Total Pages : 441 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Autophagy of the Nervous System by : Zhenyu Yue

Download or read book Autophagy of the Nervous System written by Zhenyu Yue and published by World Scientific. This book was released on 2012 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy.

Exercise, Autophagy and Chronic Diseases

Author : Ning Chen
Publisher : Springer Nature
ISBN 13 : 9811645256
Total Pages : 267 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Exercise, Autophagy and Chronic Diseases by : Ning Chen

Download or read book Exercise, Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.