The Role of Tumor Cell-vascular Endothelial Cell Interaction in the Metastasis of Subclones of a Human CLL B Cell Line [microform]

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Publisher : National Library of Canada = Bibliothèque nationale du Canada
ISBN 13 : 9780315936409
Total Pages : pages
Book Rating : 4.9/5 (364 download)

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Book Synopsis The Role of Tumor Cell-vascular Endothelial Cell Interaction in the Metastasis of Subclones of a Human CLL B Cell Line [microform] by : Lan Chen

Download or read book The Role of Tumor Cell-vascular Endothelial Cell Interaction in the Metastasis of Subclones of a Human CLL B Cell Line [microform] written by Lan Chen and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Role of Endothelial Cell-tumor Cell Interaction in Tumor Metastasis

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Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis The Role of Endothelial Cell-tumor Cell Interaction in Tumor Metastasis by : Marwan E El-Sabban

Download or read book The Role of Endothelial Cell-tumor Cell Interaction in Tumor Metastasis written by Marwan E El-Sabban and published by . This book was released on 1993 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Signaling and the Cytoskeleton

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Publisher : Springer Science & Business Media
ISBN 13 : 3662129930
Total Pages : 293 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Signaling and the Cytoskeleton by : Kermit L. Carraway

Download or read book Signaling and the Cytoskeleton written by Kermit L. Carraway and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

Multiple Myeloma

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Publisher : Springer Science & Business Media
ISBN 13 : 3540857729
Total Pages : 349 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Multiple Myeloma by : Thomas Moehler

Download or read book Multiple Myeloma written by Thomas Moehler and published by Springer Science & Business Media. This book was released on 2011-04-21 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Bispecific Antibodies

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Publisher : Springer Science & Business Media
ISBN 13 : 3642209106
Total Pages : 381 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Bispecific Antibodies by : Roland E. Kontermann

Download or read book Bispecific Antibodies written by Roland E. Kontermann and published by Springer Science & Business Media. This book was released on 2011-07-21 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.

Alphaherpesviruses

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Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455769
Total Pages : 0 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Alphaherpesviruses by : Sandra Knowles Weller

Download or read book Alphaherpesviruses written by Sandra Knowles Weller and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

The Journal of the Arkansas Medical Society

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Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis The Journal of the Arkansas Medical Society by : Arkansas Medical Society

Download or read book The Journal of the Arkansas Medical Society written by Arkansas Medical Society and published by . This book was released on 1916 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vertebral Lesions

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Publisher : Springer
ISBN 13 : 3319526340
Total Pages : 169 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Vertebral Lesions by : Luigi Manfrè

Download or read book Vertebral Lesions written by Luigi Manfrè and published by Springer. This book was released on 2017-09-06 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This easy-to-consult guide describes new minimally invasive procedures for the treatment of vertebral lesions that are accompanied by fewer complications and side-effects, reduce the risks of anesthesia, and lower costs. Clear accounts are provided of CT and X-ray guided techniques for vertebral augmentation in different regions of the spine and for the treatment of vertebral tumors by means of cryoablation, radiofrequency ablation, and embolization. Helpful information is also provided on imaging, biomechanics, biopsy, and biomaterials. Like other books in the Springer series New Procedures in Spinal Interventional Neuroradiology, this practice-oriented volume will fill a significant gap in the literature and meet the need expressed by a large number of specialists (interventional neuroradiologists and radiologists, neurosurgeons, and orthopedists) for a topical and handy guide that specifically illustrates the presently available materials and methods.

Chromosome 12 Aberrations in Human Solid Tumors

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Publisher : Springer
ISBN 13 : 9783662062579
Total Pages : 194 pages
Book Rating : 4.0/5 (625 download)

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Book Synopsis Chromosome 12 Aberrations in Human Solid Tumors by : Jörn Bullerdiek

Download or read book Chromosome 12 Aberrations in Human Solid Tumors written by Jörn Bullerdiek and published by Springer. This book was released on 2013-07-13 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers involved in the cytogenetics and molecular genetics of human tumors will welcome this comprehensive overview of the type of aberrations that chromosome 12 presents in human solid tumors. The authors study the implications for a cytogenetic subtyping of the tumors involved and strategies for identifying the molecular changes which underlie the karyotypic alterations. The aberrations of chromosome 12 which the book deals with are very frequent chromosomal alterations in human tumors occuring in frequent benign mesenchymal tumors, such as uterine leiomyomas and lipomas, and in tumors of epithelial origin, such as pleomorphic adenomas of the salivary glands.