The Role Of Oxygen Radicals In Cardiovascular Diseases

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The Role of Oxygen Radicals in Cardiovascular Diseases

Author : A. L'Abbate
Publisher : Springer Science & Business Media
ISBN 13 : 9400926979
Total Pages : 356 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Role of Oxygen Radicals in Cardiovascular Diseases by : A. L'Abbate

Download or read book The Role of Oxygen Radicals in Cardiovascular Diseases written by A. L'Abbate and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing experimental evidence is beeing produced in support of the thesis that lipid pe,oxidation is an important mediator of both vascular and myocardial tissue derangement. Although the role of the free-radical system in human cardiovascular pathology remains speculative, nevertheless the potential implications of such a system in both pharmacological therapy and prevention of major cardiovascular diseases, such as myocardial infarction, cardiomyopathy and arrhythmias, justify the increasing interest of clinical cardiologists in this research area. Furthermore, present-day clinical cardiology permits to reproduce in man such experimental models as ischemia and reperfusion, e.g. during percutaneous transluminal angioplasty, and even to gain histological and histochemical access to byoptic myocardial tissue. Upon above premises the idea of a multidisciplinary discussion meeting was conceived, aimed to confront clinical expectations with acquired basic information, and to discuss the validity of experimental models in the light of pathological and clinical findings in man. To this purpose, a unique group of experts in the field of free-radicals, from all over the world, was asked to make the topic accessible to clinical cardiologists, with the primary aim of projecting results and ideas towards potential clinical research; this is, in fact, the object of the European Concerted Action "Breakdown in Human Adaptation - Cardiovascular Diseases", in the frame of which the meeting was held.

Oxygen Radicals in the Pathophysiology of Heart Disease

Author : Pawan K. Singal
Publisher : Springer Science & Business Media
ISBN 13 : 1461317436
Total Pages : 349 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Oxygen Radicals in the Pathophysiology of Heart Disease by : Pawan K. Singal

Download or read book Oxygen Radicals in the Pathophysiology of Heart Disease written by Pawan K. Singal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over two centuries ago, oxygen was discovered as "air vital": the component of the earth's atmosphere necessary for life. Less than five years after this discovery, it was found that oxygen was both a life-sustaining and life threatening inhalant as it plays a role in the two extremes of the animal kingdom: life and death. In the subse quent years, we have made major strides in understanding the role of oxygen in maintaining life and volumes of information are now available on this topic. Our knowledge of the contribution of oxygen in cellular dysfunction and cell death which for the most part had lagged behind has begun to catch up. The deleterious ef fects of oxygen radicals and activated oxygen species on a variety of biological systems have now been described. Recently attention has also been focused on the toxic effects of oxygen on the cardiovascular system. The major aim of the present treatise is to offer an integrated view of the pathophysiological aspects of oxygen toxicity in the heart and blood vessels coupled with a review of therapeutic approaches (hopes?) with free radical scavengers and antioxidants. Internationally known expert investigators provide a concise and critical review on the topic of their expertise which also contains data from their own research.

Reactive Oxygen Species and the Cardiovascular System

Author : Augusto C. Montezano
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615043624
Total Pages : 105 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Reactive Oxygen Species and the Cardiovascular System by : Augusto C. Montezano

Download or read book Reactive Oxygen Species and the Cardiovascular System written by Augusto C. Montezano and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) influence various physiological processes including host defense, hormone biosynthesis, and cellular signaling. Increased ROS production (oxidative stress) is implicated in many diseases of the cardiovascular system, including hypertension, atherosclerosis, cardiac failure, stroke, diabetes, and kidney disease. ROS are produced throughout the cardiovascular system, in the kidney and central and peripheral nervous system. A major source for cardiovascular, renal, and neural ROS is a family of non-phagocytic NAD(P)H oxidases, including the prototypic Nox2 homologue-based NAD(P)H oxidase, as well as other NAD(P)H oxidases, such as Nox1 and Nox4. Other possible sources include mitochondrial electron transport enzymes, xanthine oxidase, cyclooxygenase, lipoxygenase, and uncoupled nitric oxide synthase (NOS). NAD(P)H oxidase-derived ROS is important in regulating endothelial function and vascular tone and oxidative stress is implicated in endothelial dysfunction, inflammation, hypertrophy, apoptosis, migration, fibrosis, angiogenesis and rarefaction, important processes involved in vascular remodeling in cardiovascular disease. These findings have evoked considerable interest because of the possibilities that therapies targeted against non-phagocytic NAD(P)H oxidase to decrease ROS generation and/or strategies to increase nitric oxide (NO) availability and antioxidants may be useful in minimizing vascular injury and thereby prevent or regress target organ damage associated with hypertension and other cardiovascular diseases.

The Role of Oxygen Radicals in Cardiovascular Diseases

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis The Role of Oxygen Radicals in Cardiovascular Diseases by :

Download or read book The Role of Oxygen Radicals in Cardiovascular Diseases written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modulation of Oxidative Stress in Heart Disease

Author : Sajal Chakraborti
Publisher : Springer Nature
ISBN 13 : 9811389462
Total Pages : 686 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Modulation of Oxidative Stress in Heart Disease by : Sajal Chakraborti

Download or read book Modulation of Oxidative Stress in Heart Disease written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-10 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.

Oxidative Stress and Vascular Disease

Author : John F. Keaney Jr.
Publisher : Springer Science & Business Media
ISBN 13 : 9780792386780
Total Pages : 404 pages
Book Rating : 4.3/5 (867 download)

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Book Synopsis Oxidative Stress and Vascular Disease by : John F. Keaney Jr.

Download or read book Oxidative Stress and Vascular Disease written by John F. Keaney Jr. and published by Springer Science & Business Media. This book was released on 1999-12-31 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.

Biological Consequences of Oxidative Stress

Author : Lawrence Spatz
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biological Consequences of Oxidative Stress by : Lawrence Spatz

Download or read book Biological Consequences of Oxidative Stress written by Lawrence Spatz and published by Oxford University Press, USA. This book was released on 1992 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen radicals are highly reactive forms of oxygen that upset the body's normal chemistry. They are created by the reaction of oxygen with radiation, air pollution, and other environmental agents, or generated in metabolism by one-electron transfers to an unstable oxygen molecule. Reactive species of oxygen and the damage they cause have been implicated in a variety of diseases. This volume focuses on their possible role in cardiovascular disease and cancer. It examines the molecular mechanisms by which oxidative damage occurs, the consequences of that damage, and some of the ways in which the damage might be mitigated. The book is based on a study group sponsored by the Conte Institute for Environmental Health, Pittsfield, Massachusetts.

Molecular and Cellular Effects of Nutrition on Disease Processes

Author : Grant N. Pierce
Publisher : Springer Science & Business Media
ISBN 13 : 1461557631
Total Pages : 227 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular and Cellular Effects of Nutrition on Disease Processes by : Grant N. Pierce

Download or read book Molecular and Cellular Effects of Nutrition on Disease Processes written by Grant N. Pierce and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the 2nd World Conference of the International Society for Molecular Nutrition & Therapy. This conference was held on August 2-4, 1997, in Winnipeg, Canada. The goal of the conference was to advance our knowledge concerning the molecular events which link nutrition to various disease processes in the body. This volume represents an important compilation of unique articles addressing the molecular and cellular basis for the nutritional and therapeutic treatment of five general disease processes.

Oxidative Stress Revisited - Major Role in Vascular Diseases

Author : Cristina M. Sena
Publisher : Frontiers Media SA
ISBN 13 : 2889630587
Total Pages : 158 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Oxidative Stress Revisited - Major Role in Vascular Diseases by : Cristina M. Sena

Download or read book Oxidative Stress Revisited - Major Role in Vascular Diseases written by Cristina M. Sena and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is an underlying factor in health and disease. Reactive oxygen species are produced as a result of normal cellular metabolism. The subsequent altered redox state between the formation and the neutralization of pro-oxidants results in their increased levels and therefore leads to cellular damage. Different research disciplines have increased our knowledge of the importance of this cell redox status and the recognition of oxidative stress as a process with implications for many pathophysiological states. Genetic and environmental factors, nutrition and lifestyle may indicate a pro-oxidative and pro-inflammatory state, linked to alterations in cellular structure and function. Oxidative stress emerges as a common, unifying factor in several conditions including diabetes and cardiovascular diseases. This eBook aims to provide novel data regarding the role played by oxidative stress and inflammation in the development of chronic diseases and the different classes of therapeutics from the bench to the clinic, stressing the awareness of these concepts for the treatment of disease. In addition, articles addressing an overview of the role of oxidative stress in vascular diseases reviewing some current concepts indicating that oxidative stress and inflammation are key mechanisms linking vascular diseases and current state-of-the-art approaches to monitor, prevent and inhibit oxidative stress will be highlighted. There is a close relation between oxidative stress, inflammation and cardiovascular diseases. Despite the great amount of investigation carried out in the field, there are still uncertainties about the mechanisms by which free radicals can modify tissues such as perivascular adipose tissue that ultimately will reflect on vascular function. This eBook will focus on articles that can explore and identify these mechanisms. Concurrent with this understanding of oxidative stress milieu, it is necessary to recognize the need for new pharmacological tools effective in restoring oxidative balance. The abundance of new information and the paradigm shift in our understanding of how antioxidants and other redox-active drugs work in a wide variety of vascular diseases will be specifically highlighted. This eBook will provide a comprehensive, up-to-date source of information on the design and mechanistic, pharmacological, and medicinal aspects of redox-active therapeutics. Finally, a unique feature of the eBook is to provide a way to foster an enthralling discussion revisiting old paradigms and finding new solutions for the treatment of vascular diseases. The topic will include original research articles, hypotheses, perspectives and (mini)reviews from experts in the field. The next decade shows promise for the translation of this body of knowledge to novel human therapeutics and this eBook will enable to increment our knowledge in this field.

Free Radicals in Human Health and Disease

Author : Vibha Rani
Publisher : Springer
ISBN 13 : 8132220358
Total Pages : 427 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Free Radicals in Human Health and Disease by : Vibha Rani

Download or read book Free Radicals in Human Health and Disease written by Vibha Rani and published by Springer. This book was released on 2014-11-14 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.

Oxidative Stress in Heart Diseases

Author : Sajal Chakraborti
Publisher : Springer Nature
ISBN 13 : 9811382735
Total Pages : 596 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Oxidative Stress in Heart Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Oxygen Free Radicals in Tissue Damage

Author : TARR,M.
Publisher : Springer Science & Business Media
ISBN 13 : 1461598400
Total Pages : 306 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oxygen Free Radicals in Tissue Damage by : TARR,M.

Download or read book Oxygen Free Radicals in Tissue Damage written by TARR,M. and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.

Oxygen Radicals and the Disease Process

Author : Craig Thomas
Publisher : CRC Press
ISBN 13 : 9789057022265
Total Pages : 304 pages
Book Rating : 4.0/5 (222 download)

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Book Synopsis Oxygen Radicals and the Disease Process by : Craig Thomas

Download or read book Oxygen Radicals and the Disease Process written by Craig Thomas and published by CRC Press. This book was released on 1998-03-18 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed investigation into the evidence implicating oxygen radicals in the etiology of eleven different human diseases or conditions. World renowned experts from each discipline review the data supporting this involvement, and discuss the full implications that result. Topics covered include Alzheimer's disease, cerebral ischemia, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, ARDS, critical care medicine and cancer. This book not only provides an invaluable resource for those seeking up to date information on the evidence supporting the involvement of oxygen radicals in human disease, but also instigates theoretical discussion of future research endeavors.

Reactive Oxygen Species in Biology and Human Health

Author : Shamim I. Ahmad
Publisher : CRC Press
ISBN 13 : 1498735460
Total Pages : 575 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Reactive Oxygen Species in Biology and Human Health by : Shamim I. Ahmad

Download or read book Reactive Oxygen Species in Biology and Human Health written by Shamim I. Ahmad and published by CRC Press. This book was released on 2017-12-19 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike other narrowly focused books, Reactive Oxygen Species in Biology and Human Health provides a comprehensive overview of ROS. It covers the current status of research and provides pointers to future research goals. Additionally, it authoritatively reviews the impact of reactive oxygen species with respect to various human diseases and discusses antioxidants and other compounds that counteract oxidative stress. Comprised of seven sections, the first section describes the introduction, detection, and production of ROS, emphasizing phenolic compounds and vitamin E for their abilities to act as antioxidants. This section also highlights the role of lipoprotein-associated oxidative stress. Section two addresses the importance of iron accumulation in the brain resulting in the development of a group of neurodegenerative disorders (NDs) and identifies several causative genes for neurodegeneration with brain iron accumulation (NBIA) associated with Parkinsonism-related disorders. The third section discusses a number of NDs, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Huntington's disease (HD), epilepsy, and multiple sclerosis (MS). Section four addresses autoimmune diseases caused by ROS, including asthma, autoimmune liver diseases, rheumatoid arthritis, thyroid disease, primary biliary cirrhosis, and systemic lupus. Section five analyzes a number of different cancers, including lung cancer, breast cancer, and melanoma, along with possible treatment regimens. Section six discusses cardiovascular diseases (CVDs) induced by ROS, presents the ROS-associated complex biochemical processes inducing inflammation as an important cause of CVDs, and explains the roles carotenoids play in preventing CVDs. The final section addresses other human diseases induced by oxidative stress, including sickle cell disease, nonalcoholic steatohepatitis, retinopathy, fibromyalgia, chronic obstructive pulmonary disease, asthma, pulmonary hypertension, infertility, and aging of human skin.

Free Radicals in Biology and Medicine

Author : Barry Halliwell
Publisher : OUP Oxford
ISBN 13 : 0191026980
Total Pages : 961 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by OUP Oxford. This book was released on 2015-08-21 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Oxygen/Nitrogen Radicals: Cell Injury and Disease

Author : Val Vallyathan
Publisher : Springer Science & Business Media
ISBN 13 : 1461510872
Total Pages : 393 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oxygen/Nitrogen Radicals: Cell Injury and Disease by : Val Vallyathan

Download or read book Oxygen/Nitrogen Radicals: Cell Injury and Disease written by Val Vallyathan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Antioxidants in Sport Nutrition

Author : Manfred Lamprecht
Publisher : CRC Press
ISBN 13 : 1466567570
Total Pages : 304 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Antioxidants in Sport Nutrition by : Manfred Lamprecht

Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.