The Regulation of DNA Replication and Transcription

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Author :
Publisher : Demos Medical Publishing
ISBN 13 : 1617051829
Total Pages : 221 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis The Regulation of DNA Replication and Transcription by : Mirko Beljanski, PhD

Download or read book The Regulation of DNA Replication and Transcription written by Mirko Beljanski, PhD and published by Demos Medical Publishing. This book was released on 2013-03-26 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Regulation of DNA Replication and Transcription explores basic processes of DNA replication and transcription in an effort to identify the mechanisms responsible for the release of genetic information and its role in the regulation of cellular events. Concerned with discovering the fundamental concept that might integrate and explain the wide range of existing lines of evidence, the author reports and interprets the results of experiments conducted in an impressive range of biological systems. Focused on complex mechanisms at the biochemical level, these studies allow analysis of the pathways involved when cells, organs and animal systems react to various trigger molecules derived from both living cells and exogenous sources. These include hormones, RNA, RNA fragments, alkaloids, actinomycin D, and phorbol esters, as well as chemical carcinogens and drugs. Comnining the results of these studies with his own extensive work in this field, the author is able to formulate a uniquely integrative biochemical model for the gene expression, demonstrating that both biological and chemically synthesized molecules can trigger the differential release of information from the DNA and thus influence cell transformation. Apart from its academic significance, the model offers high potential assistance in the search for ways to induce or control the expression of certain genes and, moreover, to promote differentiation of given cells in vitro as well as in situ.

The Regulation of DNA Replication and Transcription

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Author :
Publisher : S Karger Ag
ISBN 13 : 9783805536318
Total Pages : 189 pages
Book Rating : 4.5/5 (363 download)

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Book Synopsis The Regulation of DNA Replication and Transcription by : Mirko Beljanski

Download or read book The Regulation of DNA Replication and Transcription written by Mirko Beljanski and published by S Karger Ag. This book was released on 1983 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Regulation of DNA Replication and Transcription

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Author :
Publisher :
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Regulation of DNA Replication and Transcription by : Carl M. Mansfield

Download or read book The Regulation of DNA Replication and Transcription written by Carl M. Mansfield and published by . This book was released on 1976 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transcription Factors and DNA Replication

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Author :
Publisher : R. G. Landes
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Transcription Factors and DNA Replication by : David Scott Pederson

Download or read book Transcription Factors and DNA Replication written by David Scott Pederson and published by R. G. Landes. This book was released on 1994 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Initiation of DNA synthesis: a general model from studies with prokaryotes. Regulatory transcription factors and the initiation of transcription in eucaryotic cells. Replication origins and the initiation of DNA synthesis in mammalian cells and the viruses. DNA replication in yeast. Transcription factors and control of DNA replication.

Replication and Transcription of Chromatin

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Publisher : CRC Press
ISBN 13 : 9780849368035
Total Pages : 288 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis Replication and Transcription of Chromatin by : Roumen G. Tsanev

Download or read book Replication and Transcription of Chromatin written by Roumen G. Tsanev and published by CRC Press. This book was released on 1992-11-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Replication and Transcription of Chromatin summarizes the main structural features of chromatin and presents results on replication and transcription gained over the last 20 years. The book emphasizes DNA-histone complexes and their importance in restricting genetic information encoded in DNA. Figures are used to illustrate many of the most important concepts of chromatin replication and transcription, and promising hypotheses and models are discussed to promote further research. Replication and Transcription of Chromatin is an important reference for biochemists, biophysicists, molecular biologists, cell biologists, and other researchers interested in this topic.

Anatomy of Gene Regulation

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521804745
Total Pages : 300 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Anatomy of Gene Regulation by : Panagiotis A. Tsonis

Download or read book Anatomy of Gene Regulation written by Panagiotis A. Tsonis and published by Cambridge University Press. This book was released on 2003-01-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of contents

Concepts of Biology

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Publisher :
ISBN 13 : 9781680921021
Total Pages : 624 pages
Book Rating : 4.9/5 (21 download)

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Book Synopsis Concepts of Biology by : Samantha Fowler

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2017-12-30 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market. Concepts of Biology includes interesting applications, features a rich art program, and conveys the major themes of biology. The images in this textbook are grayscale.

Fundamental Aspects of DNA Replication

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9533072598
Total Pages : 322 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Fundamental Aspects of DNA Replication by : Jelena Kusic-Tisma

Download or read book Fundamental Aspects of DNA Replication written by Jelena Kusic-Tisma and published by BoD – Books on Demand. This book was released on 2011-09-26 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring.

DNA Replication Control in Microbial Cell Factories

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Publisher : Springer
ISBN 13 : 3319105337
Total Pages : 56 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis DNA Replication Control in Microbial Cell Factories by : Monika Glinkowska

Download or read book DNA Replication Control in Microbial Cell Factories written by Monika Glinkowska and published by Springer. This book was released on 2014-09-23 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.

Stress-Activated Protein Kinases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540755691
Total Pages : 322 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Stress-Activated Protein Kinases by : Francesc Posas

Download or read book Stress-Activated Protein Kinases written by Francesc Posas and published by Springer Science & Business Media. This book was released on 2008-01-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.

DNA Replication

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Publisher : Springer
ISBN 13 : 9811069557
Total Pages : 581 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis DNA Replication by : Hisao Masai

Download or read book DNA Replication written by Hisao Masai and published by Springer. This book was released on 2018-01-22 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells’ strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts are being generated to explain how genome DNA replication is achieved with such high adaptability and plasticity. With the development of new methods including cryoelectron microscopy analyses of huge protein complexes, single molecular analyses of initiation and elongation of DNA replication, and total reconstitution of eukaryotic DNA replication with purified factors, the field is enjoying one of its most exciting moments, and this highly timely book conveys that excitement to all interested readers.

DNA Replication, Recombination, and Repair

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Publisher : Springer
ISBN 13 : 443155873X
Total Pages : 548 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis DNA Replication, Recombination, and Repair by : Fumio Hanaoka

Download or read book DNA Replication, Recombination, and Repair written by Fumio Hanaoka and published by Springer. This book was released on 2016-01-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.

The Regulation of DNA Replication and Transcription

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Author :
Publisher : Demos Medical Publishing
ISBN 13 : 1620700190
Total Pages : 221 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis The Regulation of DNA Replication and Transcription by : Mirko Beljanski

Download or read book The Regulation of DNA Replication and Transcription written by Mirko Beljanski and published by Demos Medical Publishing. This book was released on 2013-03-26 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Regulation of DNA Replication and Transcription explores basic processes of DNA replication and transcription in an effort to identify the mechanisms responsible for the release of genetic information and its role in the regulation of cellular events. Concerned with discovering the fundamental concept that might integrate and explain the wide range of existing lines of evidence, the author reports and interprets the results of experiments conducted in an impressive range of biological systems. Focused on complex mechanisms at the biochemical level, these studies allow analysis of the pathways involved when cells, organs and animal systems react to various trigger molecules derived from both living cells and exogenous sources. These include hormones, RNA, RNA fragments, alkaloids, actinomycin D, and phorbol esters, as well as chemical carcinogens and drugs. Comnining the results of these studies with his own extensive work in this field, the author is able to formulate a uniquely integrative biochemical model for the gene expression, demonstrating that both biological and chemically synthesized molecules can trigger the differential release of information from the DNA and thus influence cell transformation. Apart from its academic significance, the model offers high potential assistance in the search for ways to induce or control the expression of certain genes and, moreover, to promote differentiation of given cells in vitro as well as in situ. "

Systems Biology of Cancer

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Publisher : Cambridge University Press
ISBN 13 : 0521493390
Total Pages : 597 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam

Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Bacterial Transcription Factors and the Cell Cycle

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Publisher : Frontiers Media SA
ISBN 13 : 2889743241
Total Pages : 193 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Bacterial Transcription Factors and the Cell Cycle by : Morigen Morigen

Download or read book Bacterial Transcription Factors and the Cell Cycle written by Morigen Morigen and published by Frontiers Media SA. This book was released on 2022-02-10 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regulation of DNA Replication and Transcription: Functional and Structural Analysis of SV40- and Monkey-derived CIS-acting Elements

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Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.:/5 (27 download)

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Book Synopsis Regulation of DNA Replication and Transcription: Functional and Structural Analysis of SV40- and Monkey-derived CIS-acting Elements by : Paul J. Szymanski

Download or read book Regulation of DNA Replication and Transcription: Functional and Structural Analysis of SV40- and Monkey-derived CIS-acting Elements written by Paul J. Szymanski and published by . This book was released on 1990 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: