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The Nocebo Effect And Its Consequences For Clinical Trials And Clinical Practice
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Book Synopsis The nocebo effect and its consequences for clinical trials and clinical practice by : Karolina A. Wartolowska
Download or read book The nocebo effect and its consequences for clinical trials and clinical practice written by Karolina A. Wartolowska and published by Frontiers Media SA. This book was released on 2023-02-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Placebo and Pain by : Bettina K. Doering
Download or read book Placebo and Pain written by Bettina K. Doering and published by Elsevier Inc. Chapters. This book was released on 2013-08-28 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nocebo effects are extremely common in clinical practice, and they are induced by a patient’s negative expectancies about a treatment outcome. They may occur after an inert treatment, or after the administration of a pharmacologically active substance, and modulate the treatment outcome. Nocebo effects in clinical practice manifest themselves in the deterioration of a pre-existing symptomatology or in the development of new symptoms that are often considered as nonspecific side effects and are ascribed to the medical regimen. Nocebo responses can be induced by components of the therapeutic encounter, e.g. the communication of the diagnosis, information about the treatment, the disclosure of risks and benefits of the treatment, or the verbal interaction during the treatment. This chapter reviews empirical evidence from clinical populations that documents nocebo effects in the different stages of the therapeutic process. Based on this review, it suggests strategies for the minimization of nocebo effects in clinical practice.
Download or read book Pain written by Alaa Abd-Elsayed and published by Springer. This book was released on 2019-05-10 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise but comprehensive guide covers common procedures in pain management necessary for daily practice, and includes topics on international pain medicine curricula, for example, the American Board of Anesthesiology, World Institute of Pain/Fellow of Interventional Pain Practice, and American Board of Pain Medicine. Treatments for pain are discussed, including nerve blocks (head, neck, back, pelvis and lower extremity). Chapters have a consistent format including high yield points for exams, and questions in the form of case studies. Pain: A Review Guide is aimed at trainees in pain medicine all over the world. This book will also be beneficial to all practitioners who practice pain.
Book Synopsis Placebo and Nocebo Effects in Psychiatry and Beyond by : Paul Enck
Download or read book Placebo and Nocebo Effects in Psychiatry and Beyond written by Paul Enck and published by Frontiers Media SA. This book was released on 2020-10-08 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition by : Michael Doherty
Download or read book Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition written by Michael Doherty and published by Oxford University Press. This book was released on 2016-10-06 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or supportive. The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. This edition also now includes new sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning. Also highly illustrated, the textbook is a strong reference tool with summary boxes and key points at the end of chapters making it easy to find information quickly and help you deliver the optimum patient outcome. The textbook equips rheumatologists and musculoskeletal health professionals with the knowledge to provide best possible patient care.
Download or read book Placebo and Pain written by Luana Colloca and published by Academic Press. This book was released on 2013-08-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers' knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain:"This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School - Contains historical aspects of the placebo effect - Discusses biological and psychological mechanisms of placebo analgesic responses - Reviews implications of the placebo effect for clinical research and pain management - Includes methodological and ethical aspects of the placebo effect
Book Synopsis Essentials of Clinical Research by : Stephen P. Glasser
Download or read book Essentials of Clinical Research written by Stephen P. Glasser and published by Springer. This book was released on 2014-06-02 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.
Download or read book Placebo and Pain written by Luana Colloca and published by Elsevier Inc. Chapters. This book was released on 2013-08-28 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: The defining circumstances and reasons for promoting healing processes based on placebo and avoiding (undesirable) nocebo effects in clinical practice represent a challenge for translational and patient-oriented medicine. Exploiting placebos and placebo effects for the benefit of the patient requires a rigorous evaluation of potential benefits and harms associated with these interventions. Moreover, any attempts to harness placebo benefits and mitigate nocebo effects in clinical practice should be done consistently with professional norms and integrity, and ethical-legal requirements of informed consent. This chapter systematically discusses the complex issue of professional and ethical requirements in using placebos and placebo effects in pain-related research and practices. Within this scope, some important questions need to be addressed as well: (a) Can placebo analgesic effects produce clinically significant benefits? (b) What translational research is being done, or should be done? (c) What work is being done in this area to enable and encourage doctors to incorporate ethically the concept of placebo and nocebo effects into their work?
Download or read book Placebo written by Fabrizio Benedetti and published by Springer. This book was released on 2014-10-10 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.
Book Synopsis Practical Management of Complex Cancer Pain by : Manohar Sharma
Download or read book Practical Management of Complex Cancer Pain written by Manohar Sharma and published by Oxford Specialist Handbooks in. This book was released on 2014-02 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Management of Complex Cancer Pain provides practical advice on advanced pain management techniques for cancer pain. Comprehensive case histories give readers insight into the treatment of pain management.
Book Synopsis Handbook of Primary Care Ethics by : Andrew Papanikitas
Download or read book Handbook of Primary Care Ethics written by Andrew Papanikitas and published by CRC Press. This book was released on 2017-09-25 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters revolving around practical issues and real-world contexts, this Handbook offers much-needed insights into the ethics of primary healthcare. An international set of contributors from a broad range of areas in ethics and practice address a challenging array of topics. These range from the issues arising in primary care interactions, to working with different sources of vulnerability among patients, from contexts connected with teaching and learning, to issues in relation to justice and resources. The book is both interdisciplinary and inter-professional, including not just ‘standard’ philosophical clinical ethics but also approaches using the humanities, clinical empirical research, management theory and much else besides. This practical handbook will be an invaluable resource for anyone who is seeking a better appreciation and understanding of the ethics ‘in’, ‘of’ and ‘for’ primary healthcare. That includes clinicians and commissioners, but also policymakers and academics concerned with primary care ethics. Readers are encouraged to explore and critique the ideas discussed in the 44 chapters; whether or not readers agree with all the authors’ views, this volume aims to inform, educate and, in many cases, inspire. Chapter 4 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.
Book Synopsis Neurobiology of the Placebo Effect Part II by :
Download or read book Neurobiology of the Placebo Effect Part II written by and published by Academic Press. This book was released on 2018-08-23 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics. Presents the latest information on placebo studies in clinically relevant models Provides current research and projects on involved brain circuitry and neurotransmitter systems Contains specific chapters on applications
Book Synopsis Placebo Effects by : Fabrizio Benedetti
Download or read book Placebo Effects written by Fabrizio Benedetti and published by . This book was released on 2009 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to critically review the mechanisms of placebo effects across all medical conditions, diseases and therapies. It is the definitive text on the placebo effect, and will be essential for researchers and clinicians in all medical specialties.
Book Synopsis Placebo Effects: The Meaning of Care in Medicine by : Pekka Louhiala
Download or read book Placebo Effects: The Meaning of Care in Medicine written by Pekka Louhiala and published by Springer Nature. This book was released on 2020-03-24 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a perspective on the concepts placebo and placebo effects, which has been missing so far: a detailed analysis of the history of the terms, their current use, suggested alternatives and the implications of the conceptual confusion. Everybody knows something about placebos and placebo effects. If, however, people are asked to define the concepts, the spectrum becomes wide. Does 'placebo' refer to an inert treatment or does it cover all elements of the patient-physician-interaction except for pharmacological or other physiological mechanisms? Furthermore, if, by definition, a placebo has no effect, what sense does it make to talk about a 'placebo effect'? Even in scientific literature the concepts ‘placebo’ and ‘placebo effect’ are used in many senses and often in a confusing way. While this book discusses many issues which keep puzzling physicians, it also covers the historical developments of the concepts of placebo and placebo effect as well as the conceptual confusion in the definitions. This book is intended for physicians, philosophers, psychologists and any other people interested in placebos, placebo effects and the physician-patient relationship.
Book Synopsis Can a Brief Psychoeducational Intervention Reduce Nocebo Responding in Clinical Settings? by : Dominic Francois Burton
Download or read book Can a Brief Psychoeducational Intervention Reduce Nocebo Responding in Clinical Settings? written by Dominic Francois Burton and published by . This book was released on 2017 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Side effects are a substantial issue in clinical settings and occur more commonly if patients are anxious or have expectations about experiencing side effects. This phenomenon, known as the nocebo effect, is inadvertently strengthened by processes within standard clinical practice (e.g. the informed consent process). The current study aimed to investigate whether explaining the nocebo effect during the informed consent process, as a brief psychoeducational intervention, could reduce patient symptom reporting and perceived side effects. Eighty patients scheduled for colonoscopy and seventy-nine patients scheduled for intravenous iron infusion were randomised to receive either the intervention or standard preparation information alone before their respective procedure. The intervention was effective in reducing symptom reporting three days following the procedure for colonoscopy patients. Participants in the colonoscopy sample who received the intervention had a significantly smaller increase in symptom reporting between post-colonoscopy and three day follow-up than those in the control group (p
Book Synopsis Mind Over Medicine by : Lissa Rankin, M.D.
Download or read book Mind Over Medicine written by Lissa Rankin, M.D. and published by Hay House, Inc. This book was released on 2013-05-07 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: We’ve been led to believe that when we get sick, it’s our genetics. Or it’s just bad luck—and doctors alone hold the keys to optimal health. For years, Lissa Rankin, M.D., believed the same. But when her own health started to suffer, and she turned to Western medical treatments, she found that they not only failed to help; they made her worse. So she decided to take matters into her own hands. Through her research, Dr. Rankin discovered that the health care she had been taught to practice was missing something crucial: a recognition of the body’s innate ability to self-repair and an appreciation for how we can control these self-healing mechanisms with the power of the mind. In an attempt to better understand this phenomenon, she explored peer-reviewed medical literature and found evidence that the medical establishment had been proving that the body can heal itself for over 50 years. Using extraordinary cases of spontaneous healing, Dr. Rankin shows how thoughts, feelings, and beliefs can alter the body’s physiology. She lays out the scientific data proving that loneliness, pessimism, depression, fear, and anxiety damage the body, while intimate relationships, gratitude, meditation, sex, and authentic self-expression flip on the body’s self-healing processes. In the final section of the book, you’ll be introduced to a radical new wellness model based on Dr. Rankin’s scientific findings. Her unique six-step program will help you uncover where things might be out of whack in your life—spiritually, creatively, environmentally, nutritionally, and in your professional and personal relationships—so that you can create a customized treatment plan aimed at bolstering these health-promoting pieces of your life. You’ll learn how to listen to your body’s "whispers" before they turn to life-threatening "screams" that can be prevented with proper self-care, and you’ll learn how to trust your inner guidance when making decisions about your health and your life. By the time you finish Mind Over Medicine, you’ll have made your own Diagnosis, written your own Prescription, and created a clear action plan designed to help you make your body ripe for miracles.
Book Synopsis Talking Cures and Placebo Effects by : David A. Jopling
Download or read book Talking Cures and Placebo Effects written by David A. Jopling and published by Oxford University Press, USA. This book was released on 2008-05-29 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychodynamic psychotherapy and psychoanalysis have had to defend themselves from a barrage of criticisms throughout their history. In this book David Jopling argues that the changes achieved through therapy are really just functions of placebos that rally the mind's native healing powers. It is a bold new work that delivers yet another blow to Freud and his followers.
