The Multiple Therapeutic Targets of A20

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Publisher : Springer
ISBN 13 : 1493903985
Total Pages : 188 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis The Multiple Therapeutic Targets of A20 by : Christiane Ferran

Download or read book The Multiple Therapeutic Targets of A20 written by Christiane Ferran and published by Springer. This book was released on 2014-09-26 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target.

Managing Diabetes and Hyperglycemia in the Hospital Setting

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Publisher : American Diabetes Association
ISBN 13 : 1580406572
Total Pages : 338 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Managing Diabetes and Hyperglycemia in the Hospital Setting by : Boris Draznin

Download or read book Managing Diabetes and Hyperglycemia in the Hospital Setting written by Boris Draznin and published by American Diabetes Association. This book was released on 2016-05-20 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.

Diabetes and Hypertension

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Publisher : Springer Science & Business Media
ISBN 13 : 1603273573
Total Pages : 196 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Diabetes and Hypertension by : Samy I. McFarlane

Download or read book Diabetes and Hypertension written by Samy I. McFarlane and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832520146
Total Pages : 220 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis by : Maria Teresa Cencioni

Download or read book Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis written by Maria Teresa Cencioni and published by Frontiers Media SA. This book was released on 2023-04-10 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Targets

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118185528
Total Pages : 503 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Therapeutic Targets by : Luis M. Botana

Download or read book Therapeutic Targets written by Luis M. Botana and published by John Wiley & Sons. This book was released on 2012-04-20 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.

Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

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Publisher : Springer Science & Business Media
ISBN 13 : 1607614332
Total Pages : 328 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma by : Michael J. Murphy

Download or read book Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma written by Michael J. Murphy and published by Springer Science & Business Media. This book was released on 2011-12-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.

Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment

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Publisher : Frontiers Media SA
ISBN 13 : 283254181X
Total Pages : 156 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment by : Zhangqun Ye

Download or read book Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment written by Zhangqun Ye and published by Frontiers Media SA. This book was released on 2023-12-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known that the immune microenvironment is critical to the progression of genitourinary malignancies and benign diseases. A variety of cellular and molecular properties of the immune microenvironment may influence disease outcome by altering the balance of suppressive versus inflammatory or cytotoxic responses. Emerging evidence suggests that immunoediting is a key factor of phenotypic change, immunological alterations caused by physical activity or drug treatments could promote antitumor or anti-inflammatory activity. Conversely, microenvironment deficits or dysregulation can instigate or worsen pathological progression, thereby contributing to urinary disease development and progression. Thus, understanding how immune microenvironments react and maintain appropriate antitumor or anti-inflammatory responses is important for identifying actionable therapies to improve genitourinary health. Recent technological developments, particularly in the areas of genetic modification and redox indicators, provide hopeful new treatments not only in urinary cancer, kidney cancer, bladder cancer, relatively rare adrenocortical cancer, and penile cancer but also in begin diseases like kidney stones and kidney injuries. The purpose of this topic is to provide up-to-date reviews and original articles that highlight research on immunological mediators of tumor progression and inflammatory-related genitourinary diseases, which we hope will not only integrate our current understanding but crystallize nascent questions that will help move the field forward. This research topic aims to inspire novel insights into the immunity mechanisms, novel therapeutic targets, and effective combinational strategies of urinary immunotherapies.

Impact of Genetic Targets on Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1461461766
Total Pages : 448 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Impact of Genetic Targets on Cancer Therapy by : Wafik S El-Deiry

Download or read book Impact of Genetic Targets on Cancer Therapy written by Wafik S El-Deiry and published by Springer Science & Business Media. This book was released on 2013-01-05 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​​​The volume provides a forum for original peer-reviewed short communications, full-length research and review articles on new research findings and developments on the topic of genetic targets on cancer therapies. As the field is highly important it requires co-operation between research communities from all over the world to share their knowledge and experience in order to move the field forward. Each chapter includes a discussion of the impact of the tumor microenvironment and cancer stem cells and cover current knowledge in this area as it pertains to the disease, including emerging therapy targeting the microenvironment and/or cancer stem cells.

Targeted Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1603274243
Total Pages : 447 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Targeted Cancer Therapy by : Razelle Kurzrock

Download or read book Targeted Cancer Therapy written by Razelle Kurzrock and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This book provides a foundation of knowledge in targeted cancer therapeutics. The treatment of cancer is increasingly being individualized, based on an understanding of underlying biologic mechanisms. Poised to change the landscape in oncology, this volume provides a state-of-the-art overview. It will be valuable to practicing and academic physicians, fellows, residents and students, as well as basic scientists, interested in the cancer field.

Multi-dimensional Biomarkers and Resistance Mechanism of Targeted Therapy and Immunotherapy in Lung Cancer

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889742652
Total Pages : 196 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Multi-dimensional Biomarkers and Resistance Mechanism of Targeted Therapy and Immunotherapy in Lung Cancer by : Tao Jiang

Download or read book Multi-dimensional Biomarkers and Resistance Mechanism of Targeted Therapy and Immunotherapy in Lung Cancer written by Tao Jiang and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hepatocellular Carcinoma: Novel Treatment Strategies

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Publisher : Frontiers Media SA
ISBN 13 : 2889769267
Total Pages : 260 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Hepatocellular Carcinoma: Novel Treatment Strategies by : Fan Feng

Download or read book Hepatocellular Carcinoma: Novel Treatment Strategies written by Fan Feng and published by Frontiers Media SA. This book was released on 2022-09-12 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

TRP Channels as Therapeutic Targets

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Author :
Publisher : Academic Press
ISBN 13 : 0124200796
Total Pages : 530 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis TRP Channels as Therapeutic Targets by : Arpad Szallasi

Download or read book TRP Channels as Therapeutic Targets written by Arpad Szallasi and published by Academic Press. This book was released on 2015-04-09 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them

Emerging Therapeutic Targets in Brain Cancer

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Publisher : Frontiers Media SA
ISBN 13 : 2889762211
Total Pages : 197 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Emerging Therapeutic Targets in Brain Cancer by : Terrance Johns

Download or read book Emerging Therapeutic Targets in Brain Cancer written by Terrance Johns and published by Frontiers Media SA. This book was released on 2022-05-25 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeted Radionuclide Therapy

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451153260
Total Pages : 564 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Targeted Radionuclide Therapy by : Tod W. Speer

Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Angiogenesis & Therapeutic Targets in Cancer

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Publisher : Bentham Science Publishers
ISBN 13 : 1608050076
Total Pages : 238 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Angiogenesis & Therapeutic Targets in Cancer by : Malay Chatterjee

Download or read book Angiogenesis & Therapeutic Targets in Cancer written by Malay Chatterjee and published by Bentham Science Publishers. This book was released on 2010 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on c

Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889765814
Total Pages : 535 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets by : Varda Shoshan-Barmatz

Download or read book Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets written by Varda Shoshan-Barmatz and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emerging Therapeutic Targets in Ovarian Cancer

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441972161
Total Pages : 299 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Emerging Therapeutic Targets in Ovarian Cancer by : Stan Kaye

Download or read book Emerging Therapeutic Targets in Ovarian Cancer written by Stan Kaye and published by Springer Science & Business Media. This book was released on 2010-11-23 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: