The Microrna 2000 Transformer

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The MicroRNA 2000 Transformer

Author : Yoichi Robertus Fujii
Publisher : Springer Nature
ISBN 13 : 9819931657
Total Pages : 240 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis The MicroRNA 2000 Transformer by : Yoichi Robertus Fujii

Download or read book The MicroRNA 2000 Transformer written by Yoichi Robertus Fujii and published by Springer Nature. This book was released on 2023-09-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition includes new findings that were only a theory in the first edition, clarifying what is beginning to be proven true. All chapters have been updated, and new data on the analysis of major depressive disorder from exosome microRNA (miRNA) in plasma, traumatic brain injury, and Alzheimer's disease, brain glioma from cerebrospinal fluid miRNA, liver cancer, induced pluripotent stem (iPS) cell tumorigenesis, and other topics have been added. As predicted in the first edition, diseases can be predicted using the miRNA memory package (MMP) and miRNA entangling target sorting (METS), which could clarify the etiology of human diseases. Because researchers are investigating the relationship between circulating miRNAs and human diseases to develop new medicines, miRNA deep sequencing and detection methods will be high-speed and clever. The microRNA 2000 Transformer - Quantum Computing and Artificial Intelligence for Health is aimed at intermediate and advanced scientists, clinicians, students, and science enthusiasts. The Author hopes to lay the groundwork for future human health innovation.

The microRNA 2000: from HIV-1 to Healthcare

Author : Yoichi Robertus Fujii
Publisher : Scientific Research Publishing, Inc. USA
ISBN 13 : 1618963864
Total Pages : 279 pages
Book Rating : 4.6/5 (189 download)

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Book Synopsis The microRNA 2000: from HIV-1 to Healthcare by : Yoichi Robertus Fujii

Download or read book The microRNA 2000: from HIV-1 to Healthcare written by Yoichi Robertus Fujii and published by Scientific Research Publishing, Inc. USA. This book was released on with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: microRNA (miRNA), like a language, is full of regulators for our lives. Function of miRNAs is simple to tell – for instance, post-transcriptional suppression; however, its mechanisms are more tricky and explanation of miRNAs’ role in evolution causes difficulty even graduated students and top researchers. How exactly is the information of miRNA used? What is the difference between CeRNA theory and RNA wave 2000? What are the real rules for disease induction and cure? When do we use the expression of miRNAs? How do you say, miRNA is information and not epigene? Where does miRNA locate? When are miRNAs transmitted? And so on, and so on. This book would be a practical reference guide to problems of these kinds. But there is no point that is lie or truth. Therefore, the book is intend for not only intermediate and advanced scientists or students but also scientific enthusiasts. Being references, it contains information at various journals, ranging from review articles to very unique articles. Finally readers would decide lie or truth, or near pin or not because research of concept in miRNAs is in progress day by day by over 10,000 references per year on 2016.

The MicroRNA 2000: from HIV-1 to Healthcare

Author : Robertus Fujii Yoichi
Publisher :
ISBN 13 : 9781618963857
Total Pages : pages
Book Rating : 4.9/5 (638 download)

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Book Synopsis The MicroRNA 2000: from HIV-1 to Healthcare by : Robertus Fujii Yoichi

Download or read book The MicroRNA 2000: from HIV-1 to Healthcare written by Robertus Fujii Yoichi and published by . This book was released on 2017-04 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nutrition and Enhanced Sports Performance

Author : Debasis Bagchi
Publisher : Academic Press
ISBN 13 : 0128139234
Total Pages : 820 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nutrition and Enhanced Sports Performance by : Debasis Bagchi

Download or read book Nutrition and Enhanced Sports Performance written by Debasis Bagchi and published by Academic Press. This book was released on 2018-10-05 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Enhanced Sports Performance: Muscle Building, Endurance and Strength, Second Edition, includes comprehensive sections on the role of nutrition in human health, various types of physical exercises, including cardiovascular training, resistance training, aerobic and anaerobic exercises, bioenergetics and energy balance, and the nutritional requirements associated with each. Other sections cover sports and nutritional requirements, the molecular mechanisms involved in muscle building, an exhaustive review of various foods, minerals, supplements, phytochemicals, amino acids, transition metals, competition training, healthy cooking, physical training, and lifestyle and dietary recommendations for sports performance. This updated edition includes new chapters on mood, alertness, calmness and psychomotor performance in sports, extreme sports, natural myostatin inhibitor and lean body mass, the benefits of caffeine in sport nutrition formulations, the role of vitamin D in athletic performance, probiotics and muscle mass. Provides a comprehensive appraisal of the nutritional benefits of exercise in human health Compiles chapters reviewing the nutritional prophylaxis in human health Addresses performance enhancement drugs and sports supplements Presents various types of physical exercises and addresses exercise and nutritional requirements in special populations Discusses sports nutrition and the molecular mechanisms involved in muscle building Contains an exhaustive review of various food, minerals, supplements, phytochemicals, amino acids, transition metals, small molecules and other ergogenic agents Highlights the aspects of healthy cooking, physical training, lifestyle and dietary recommendations for sports performance

Gene Regulation

Author : David Latchman
Publisher : Garland Science
ISBN 13 : 1134217102
Total Pages : 471 pages
Book Rating : 4.1/5 (342 download)

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Book Synopsis Gene Regulation by : David Latchman

Download or read book Gene Regulation written by David Latchman and published by Garland Science. This book was released on 2007-01-24 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Environmental Endocrine Toxicants

Author : Younis Ahmad Hajam
Publisher : CRC Press
ISBN 13 : 1000779440
Total Pages : 429 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Environmental Endocrine Toxicants by : Younis Ahmad Hajam

Download or read book Environmental Endocrine Toxicants written by Younis Ahmad Hajam and published by CRC Press. This book was released on 2023-08-04 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting cutting-edge research on human exposure to endocrine toxicants and the related harmful effects, this book focuses on the challenges of dealing with increasing pollution levels, increased use of synthetic chemicals, and environmental endocrine disruptors that endanger the human endocrine system and its hormones. Found in manmade and natural substances and materials, these toxicants include pesticides, herbicides, industrial chemicals, solvents and byproducts, phytoestrogens, nanomaterials, and chemicals used in personal care products. They may mimic or interfere with the body’s hormones and are linked with developmental, reproductive, brain, immune, and other problems. The volume discusses the chemical nature and mechanisms of endocrine disruptors, their sources, the impact of endocrine toxicants on a sustainable environment, and the effect of endocrine toxicants on human health, such as on thyroid glands, on human reproduction, etc. The volume also looks at the therapeutic effects of medicinal plants on endocrine disorders in humans.

The Evolutionary Biology of Flies

Author : David K. Yeates
Publisher : Columbia University Press
ISBN 13 : 0231127006
Total Pages : 441 pages
Book Rating : 4.2/5 (311 download)

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Book Synopsis The Evolutionary Biology of Flies by : David K. Yeates

Download or read book The Evolutionary Biology of Flies written by David K. Yeates and published by Columbia University Press. This book was released on 2005 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flies (Dipteria) have had an important role in deepening scientists'understanding of modern biology and evolution. The study of flies has figured prominently in major advances in the fields of molecular evolution, physiology, genetics, phylogenetics, and ecology over the last century. This volume, with contributions from top scientists and scholars in the field, brings together diverse aspects of research and will be essential reading for entomologists and fly researchers.

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Author : Che-Pei Kung
Publisher : Frontiers Media SA
ISBN 13 : 2889630307
Total Pages : 130 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer by : Che-Pei Kung

Download or read book Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer written by Che-Pei Kung and published by Frontiers Media SA. This book was released on 2019-09-23 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.

Genetic Control of Malaria and Dengue

Author : Zach N. Adelman
Publisher : Academic Press
ISBN 13 : 0128004053
Total Pages : 487 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genetic Control of Malaria and Dengue by : Zach N. Adelman

Download or read book Genetic Control of Malaria and Dengue written by Zach N. Adelman and published by Academic Press. This book was released on 2015-10-15 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission Provides a summary of the concepts of both population suppression and population replacement Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

Biomolecular Feedback Systems

Author : Domitilla Del Vecchio
Publisher : Princeton University Press
ISBN 13 : 1400850509
Total Pages : 287 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Biomolecular Feedback Systems by : Domitilla Del Vecchio

Download or read book Biomolecular Feedback Systems written by Domitilla Del Vecchio and published by Princeton University Press. This book was released on 2014-10-26 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources. Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems. Provides a user-friendly introduction to essential concepts, tools, and applications Covers the most commonly used modeling methods Addresses the modular design problem for biomolecular systems Uses design examples from both natural systems and synthetic circuits Solutions manual (available only to professors at press.princeton.edu) An online illustration package is available to professors at press.princeton.edu

The Epstein-Barr Virus

Author : M. A. Epstein
Publisher : Springer Science & Business Media
ISBN 13 : 3642672361
Total Pages : 467 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Epstein-Barr Virus by : M. A. Epstein

Download or read book The Epstein-Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

Alternative Splicing in Brain Function

Author : Kif Liakath-Ali
Publisher : Frontiers Media SA
ISBN 13 : 2832540732
Total Pages : 171 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Alternative Splicing in Brain Function by : Kif Liakath-Ali

Download or read book Alternative Splicing in Brain Function written by Kif Liakath-Ali and published by Frontiers Media SA. This book was released on 2023-12-13 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional and structural intricacies of biological systems emerge from the complex nature of the genome. A key aspect of genome complexity can be attributed to the process of alternative splicing of precursor mRNA (or pre-mRNA), during which introns are removed and exons are selectively spliced together. This highly regulated process generates different mature mRNA transcripts from a single gene and is widespread throughout the eukaryotic evolution. The majority of the genes expressed in the mammalian central nervous system undergo extensive alternative splicing. Some genes can generate more than a thousand isoforms resulting in diverse proteoforms that can differ in their function, binding preference, catalytic activity, and localization. Perturbation in alternative splicing has been linked to many neurological disorders. Despite its significance, we still lack a comprehensive understanding of its role in neuronal function. Recent studies suggest that alternative splicing is a regulator of tissue identity and development. This is particularly relevant to the brain where developmental regulation and heterogenous cell population play a crucial role in shaping its function. For a long time, technological limitations in detecting and measuring alternatively spliced transcripts hindered the progress in understanding the biology of alternative splicing. Recent advances in long-read and native mRNA sequencing and robust computational tools allow us to capture and quantify in their full-length form. Public transcriptomics datasets can be utilized for the meta-analysis of alternative splicing landscapes of various experimental conditions and disease samples. In addition, protein isoform detection complements mRNA isoform levels. Given its biological significance and recent advances, the objective of this Research Topic is to assemble current knowledge, views, and challenges in the studies of alternative splicing in brain function.

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Author : Jan Gorodkin
Publisher : Humana
ISBN 13 : 9781627037082
Total Pages : 0 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods by : Jan Gorodkin

Download or read book RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods written by Jan Gorodkin and published by Humana. This book was released on 2014-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.

A Practical Approach to Microarray Data Analysis

Author : Daniel P. Berrar
Publisher : Springer Science & Business Media
ISBN 13 : 0306478153
Total Pages : 382 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis A Practical Approach to Microarray Data Analysis by : Daniel P. Berrar

Download or read book A Practical Approach to Microarray Data Analysis written by Daniel P. Berrar and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several years, DNA microarray technology has attracted tremendous interest in both the scientific community and in industry. With its ability to simultaneously measure the activity and interactions of thousands of genes, this modern technology promises unprecedented new insights into mechanisms of living systems. Currently, the primary applications of microarrays include gene discovery, disease diagnosis and prognosis, drug discovery (pharmacogenomics), and toxicological research (toxicogenomics). Typical scientific tasks addressed by microarray experiments include the identification of coexpressed genes, discovery of sample or gene groups with similar expression patterns, identification of genes whose expression patterns are highly differentiating with respect to a set of discerned biological entities (e.g., tumor types), and the study of gene activity patterns under various stress conditions (e.g., chemical treatment). More recently, the discovery, modeling, and simulation of regulatory gene networks, and the mapping of expression data to metabolic pathways and chromosome locations have been added to the list of scientific tasks that are being tackled by microarray technology. Each scientific task corresponds to one or more so-called data analysis tasks. Different types of scientific questions require different sets of data analytical techniques. Broadly speaking, there are two classes of elementary data analysis tasks, predictive modeling and pattern-detection. Predictive modeling tasks are concerned with learning a classification or estimation function, whereas pattern-detection methods screen the available data for interesting, previously unknown regularities or relationships.

Clinical Immunology

Author : Reginald M. Gorczynski
Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Clinical Immunology by : Reginald M. Gorczynski

Download or read book Clinical Immunology written by Reginald M. Gorczynski and published by . This book was released on 1999 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise text in immunology for medical students. It covers cellular, humoral and clinical immunology. Each chapter begins with a definition of objectives followed by clearly illustrated descriptions of immunologic mechanisms. The clinical implications of the information in each chapter are addressed.

MicroRNA in Solid Tumor and Hematological Diseases

Author : Francesca Lovat
Publisher :
ISBN 13 : 9783036530895
Total Pages : 226 pages
Book Rating : 4.5/5 (38 download)

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Book Synopsis MicroRNA in Solid Tumor and Hematological Diseases by : Francesca Lovat

Download or read book MicroRNA in Solid Tumor and Hematological Diseases written by Francesca Lovat and published by . This book was released on 2022 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs (miRNAs), which are a type of short non-coding RNA, are involved in number of processes, such as differentiation, development, inflammation, immune response, and cancer. miRNAs, which act as oncogenes or tumor suppressor genes, can control and regulate the translation and stability of target messenger RNA, contributing to cancer pathogenesis. Despite the progress that has been made in discovering the mechanisms of how miRNAs function in tumors, many questions and aspects of miRNA biology and processing still remain to be determined. This Special Issue, titled “MicroRNA in Solid Tumor and Hematological Diseases”, provides a panorama of the existing knowledge gaps and potential uses of microRNAs to predict clinical outcome or response to therapies and provides evidence to explain their role as biomarkers to modulate the biological pathways that are critical for cancer development and progression. It includes eleven peer-reviewed papers that cover the role of microRNAs in different tumor types and their potential applications in diagnosis and clinical approaches.

Working with Ferns

Author : Helena Fernández
Publisher : Springer Science & Business Media
ISBN 13 : 1441971629
Total Pages : 395 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Working with Ferns by : Helena Fernández

Download or read book Working with Ferns written by Helena Fernández and published by Springer Science & Business Media. This book was released on 2010-11-11 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well timed volume features a selection of chapters composed by experts in their respective fields. It covers a broad range of topics, from its fundamental biology to the fern’s population genetics and environmental and therapeutic applications.