The Marriott Cell

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Author :
Publisher : Random House Canada
ISBN 13 : 0345816374
Total Pages : 434 pages
Book Rating : 4.3/5 (458 download)

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Book Synopsis The Marriott Cell by : Mohamed Fahmy

Download or read book The Marriott Cell written by Mohamed Fahmy and published by Random House Canada. This book was released on 2016-11-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning journalist Mohamed Fahmy's widely anticipated account of his wrongful incarceration in Cairo's maximum-security Scorpion Prison for terrorists and political leaders, and his subsequent battle for justice, opens a remarkable window onto the closed world of Islamic fundamentalism and the bloody geopolitical struggles that dominate our headlines. An important book that reads like a political thriller, it is also a testament to the critical importance of journalism today; an inspiring love story that made front-page news; and a profoundly personal drama of one man's fight for freedom. On the night of December 29, 2013, Egyptian security forces, in a dramatic raid on the Marriott Hotel, seized Fahmy (Canadian-Egyptian Bureau Chief for Al Jazeera English) and two of his colleagues, Peter Greste and Baher Mohamed, accusing them of fabricating news as members of the outlawed Muslim Brotherhood. Their trials became a global cause célèbre condemned as a travesty. But Fahmy also never stopped being a journalist: inside Scorpion he found himself cheek by jowl with notorious Muslim Brotherhood leaders, Al Qaeda fighters, and ISIS sympathizers. Always intrepid, he took advantage of the situation to "interview" the Brotherhood about their aims, gaining exclusive insight into the geopolitical feuds between Egypt, Saudi Arabia, and the UAE on one hand and Qatar and its allies, including Turkey on the other—interviews that led him to sue his former employer, Al Jazeera, from prison. The complex power brokering of Middle Eastern and Western governments left three men trapped in a web he describes as "Global McCarthyism." But at the heart of the book is an inspiring story of two strong women: Fahmy's wife, Marwa Omara, who used every means possible to fight for his release, bravely risking her safety; and his courageous international human-rights lawyer, Amal Clooney, who championed his battle for freedom.

The Marriott Cell

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Author :
Publisher : Random House Canada
ISBN 13 : 0345816358
Total Pages : 434 pages
Book Rating : 4.3/5 (458 download)

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Book Synopsis The Marriott Cell by : Mohamed Fahmy

Download or read book The Marriott Cell written by Mohamed Fahmy and published by Random House Canada. This book was released on 2016-11-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning journalist Mohamed Fahmy's widely anticipated account of his wrongful incarceration in Cairo's maximum-security Scorpion Prison for terrorists and political leaders, and his subsequent battle for justice, opens a remarkable window onto the closed world of Islamic fundamentalism and the bloody geopolitical struggles that dominate our headlines. An important book that reads like a political thriller, it is also a testament to the critical importance of journalism today; an inspiring love story that made front-page news; and a profoundly personal drama of one man's fight for freedom. On the night of December 29, 2013, Egyptian security forces, in a dramatic raid on the Marriott Hotel, seized Fahmy (Canadian-Egyptian Bureau Chief for Al Jazeera English) and two of his colleagues, Peter Greste and Baher Mohamed, accusing them of fabricating news as members of the outlawed Muslim Brotherhood. Their trials became a global cause célèbre condemned as a travesty. But Fahmy also never stopped being a journalist: inside Scorpion he found himself cheek by jowl with notorious Muslim Brotherhood leaders, Al Qaeda fighters, and ISIS sympathizers. Always intrepid, he took advantage of the situation to "interview" the Brotherhood about their aims, gaining exclusive insight into the geopolitical feuds between Egypt, Saudi Arabia, and the UAE on one hand and Qatar and its allies, including Turkey on the other—interviews that led him to sue his former employer, Al Jazeera, from prison. The complex power brokering of Middle Eastern and Western governments left three men trapped in a web he describes as "Global McCarthyism." But at the heart of the book is an inspiring story of two strong women: Fahmy's wife, Marwa Omara, who used every means possible to fight for his release, bravely risking her safety; and his courageous international human-rights lawyer, Amal Clooney, who championed his battle for freedom.

The Marriott Cell

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Author :
Publisher : Vintage Canada
ISBN 13 : 9780345816368
Total Pages : pages
Book Rating : 4.8/5 (163 download)

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Book Synopsis The Marriott Cell by : Mohamed Fadel Fahmy

Download or read book The Marriott Cell written by Mohamed Fadel Fahmy and published by Vintage Canada. This book was released on 2018-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bad History

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Publisher : Michael O'Mara Books
ISBN 13 : 1843177773
Total Pages : 186 pages
Book Rating : 4.8/5 (431 download)

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Book Synopsis Bad History by : Emma Marriott

Download or read book Bad History written by Emma Marriott and published by Michael O'Mara Books. This book was released on 2011-09-30 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entertaining but authoritative, Bad History debunks a wealth of historical errors. In doing so, it exposes many falsehoods that have wrongly - and sometimes dangerously - influenced our understanding of the world's history.

Into the Abyss

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Publisher : Random House Canada
ISBN 13 : 0307360245
Total Pages : 297 pages
Book Rating : 4.3/5 (73 download)

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Book Synopsis Into the Abyss by : Carol Shaben

Download or read book Into the Abyss written by Carol Shaben and published by Random House Canada. This book was released on 2012-10-16 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: On an icy night in October 1984, a Piper Navajo commuter plane carrying 9 passengers crashed in the remote wilderness of northern Alberta, killing 6 people. Four survived: the rookie pilot, a prominent politician, a cop, and the criminal he was escorting to face charges. Despite the poor weather, Erik Vogel, the 24-year-old pilot, was under intense pressure to fly--a situation not uncommon to pilots working for small airlines. Overworked and exhausted, he feared losing his job if he refused to fly. Larry Shaben, the author's father and Canada's first Muslim Cabinet Minister, was commuting home after a busy week at the Alberta Legislature. After Paul Archambault, a drifter wanted on an outstanding warrant, boarded the plane, rookie Constable Scott Deschamps decided, against RCMP regulations, to remove his handcuffs--a decision that profoundly impacted the men's survival. As they fought through the night to stay alive, the dividing lines of power, wealth and status were erased and each man was forced to confront the precious and limited nature of his existence. The survivors forged unlikely friendships and through them found strength and courage to rebuild their lives. Into the Abyss is a powerful narrative that combines in-depth reporting with sympathy and grace to explore how a single, tragic event can upset our assumptions and become a catalyst for transformation.

Into the Abyss

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Author :
Publisher : Grand Central Publishing
ISBN 13 : 1455545627
Total Pages : 336 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis Into the Abyss by : Carol Shaben

Download or read book Into the Abyss written by Carol Shaben and published by Grand Central Publishing. This book was released on 2013-05-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Only four men survived the plane crash. The pilot. A politician. A cop... and the criminal he was shackled to. On an icy night in October 1984, a commuter plane carrying nine passengers crashed in the remote wilderness of northern Alberta, killing six people. Four survived: the rookie pilot, a prominent politician, a cop, and the criminal he was escorting to face charges. Despite the poor weather, Erik Vogel, the 24-year-old pilot, was under intense pressure to fly. Larry Shaben, the author's father and Canada's first Muslim Cabinet Minister, was commuting home after a busy week at the Alberta Legislature. Constable Scott Deschamps was escorting Paul Archambault, a drifter wanted on an outstanding warrant. Against regulations, Archambault's handcuffs were removed-a decision that would profoundly impact the men's survival. As the men fight through the night to stay alive, the dividing lines of power, wealth, and status are erased, and each man is forced to confront the precious and limited nature of his existence.

Marriott's Practical Electrocardiography

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451146256
Total Pages : 552 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Marriott's Practical Electrocardiography by : Galen S Wagner

Download or read book Marriott's Practical Electrocardiography written by Galen S Wagner and published by Lippincott Williams & Wilkins. This book was released on 2013-12-18 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: "One of the strengths of Marriott's Practical Electrocardiography through its more than 50-year history has been its lucid foundation for understanding the basis for ECG interpretation. Again, in this revision, we have attempted to retain the best of the Marriott tradition--emphasis on the concepts required for everyday ECG interpretation and the simplicities, rather than complexities, of the ECG recordings. During preparation of the 9th and 10th editions, Tobin Lim coauthored many of the 11th edition chapters and served as the primary developer of the digital content associated with that edition. Tobin Lim's input continues into this 12th edition, and David Strauss has led even further into the electronic-based interactive learning experiences. More than 30 of the figures that evolved through previous editions have now been converted through the creative expertise of Mark Flanders into animated movies accessed via QR codes imbedded in the book. David has also collaborated with electrocardiographic educators who are especially skilled in e-based education to add interactive video content to many of the 12th edition chapters. Each of the now 24 chapters is divided (as indicated in the table of contents) into discrete, compact "learning units." Each learning unit begins on a new page to provide blank space for the reader's notes. The purpose of the learning units is to make this book easier to use by allowing the reader to be selective regarding the material to be considered at a particular time. Because the modern student of electrocardiography is primarily oriented to a visual perspective, we have typically begun each page with an illustration"--Provided by publisher.

Advanced Concepts in Arrhythmias

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Publisher :
ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advanced Concepts in Arrhythmias by : Henry Joseph Llewellyn Marriott

Download or read book Advanced Concepts in Arrhythmias written by Henry Joseph Llewellyn Marriott and published by . This book was released on 1998 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Concepts in Arrhythmias covers all of the important and up-to-date advances in electrocardiography--reflecting all of the state-of-the-art findings that have occurred over the last few years. It is unique because it bridges the gap between basic ECG texts and the comprehensive texts that provide an overwhelming amount of information on cardiac electrophysiology. Readers will find new chapters covering the latest innovations in atrial fibrillation, atrial flutter, and polymorphic ventricular tachycardia. * Explains the mechanisms of all forms of atrial flutter, giving the reader a comprehensive presentation of this important subject matter. * Describes in just the right amount of detail the mechanisms, ECG recognition, emergency response, symptoms, and the cure of paroxysmal supraventricular tachycardia. * Discusses how to cure idiopathic ventricular tachycardia with transvenous radiofrequency ablation information not found in other references. * Offers consistent coverage that includes ECG recognition, pediatrics, mechanism, symptoms, physical assessment, and emergency treatment, giving the reader complete information for each arrhythmia. * Presents an easy-to-understand chapter on cellular electrophysiology a traditionally difficult subject allowing readers to better understand arrhythmogenic mechanisms.

The Infinite Staircase

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Author :
Publisher : BenBella Books
ISBN 13 : 1950665984
Total Pages : 233 pages
Book Rating : 4.9/5 (56 download)

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Book Synopsis The Infinite Staircase by : Geoffrey A. Moore

Download or read book The Infinite Staircase written by Geoffrey A. Moore and published by BenBella Books. This book was released on 2021-08-10 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: NAUTILUS BOOK AWARD GOLD MEDALIST — BODY, MIND, SPIRIT PRACTICES “Combining an extraordinary range of scholarship with an accessible and entertaining writing style, The Infinite Staircase . . . provides a coherent and unified platform for a full human life.” —Midwest Book Review In this bold new book, high-tech’s best-known strategist makes a seminal contribution to the search for meaning in a secular era. Two questions fundamental to human existence have always been the metaphysical “where do I fit in the grand scheme of things?” and the ethical “how should I behave?” Religion is no longer a source of answers for many people, and nothing has replaced it. Moore uses his signature framework-based approach to answer these questions, taking us on an intellectual roller coaster ride through physics, chemistry, biology, the social sciences and the humanities. Along the way, he builds a metaphorical ladder that leads from the big bang to the need for ethical action in our daily lives. Combining an extraordinary range of scholarship with an accessible and entertaining writing style, The Infinite Staircase: What the Universe Tells Us About Life, Ethics, and Mortality provides a coherent and unified platform for a full human life.

Firms of Endearment

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Publisher : Pearson Prentice Hall
ISBN 13 : 0132716178
Total Pages : 319 pages
Book Rating : 4.1/5 (327 download)

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Book Synopsis Firms of Endearment by : Rajendra Sisodia

Download or read book Firms of Endearment written by Rajendra Sisodia and published by Pearson Prentice Hall. This book was released on 2003-01-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today’s best companies get it. From Costco® to Commerce Bank, Wegmans to Whole Foods®: they’re becoming the ultimate value creators. They’re generating every form of value that matters: emotional, experiential, social, and financial. And they’re doing it for all their stakeholders. Not because it’s “politically correct”: because it’s the only path to long-term competitive advantage. These are the Firms of Endearment. Companies people love doing business with. Love partnering with. Love working for. Love investing in. Companies for whom “loyalty” isn’t just real: it’s palpable, and driving unbeatable advantages in everything from marketing to recruitment. You need to become one of those companies. This book will show you how. You’ll find specific, practical guidance on transforming every relationship you have: with customers, associates, partners, investors, and society. If you want to be great—truly great—this is your blueprint. We’re entering an Age of Transcendence, as people increasingly search for higher meaning in their lives, not just more possessions. This is transforming the marketplace, the workplace, the very soul of capitalism. Increasingly, today’s most successful companies are bringing love, joy, authenticity, empathy, and soulfulness into their businesses: they are delivering emotional, experiential, and social value–not just profits. Firms of Endearment illuminates this, the most fundamental transformation in capitalism since Adam Smith. It’s not about “corporate social responsibility”: it’s about building companies that can sustain success in a radically new era. It’s about great companies like IDEO and IKEA®, Commerce Bank and Costco®, Wegmans and Whole Foods®: how they earn the powerful loyalty and affection that enables truly breathtaking performance. This book is about gaining “share of heart,” not just share of wallet. It’s about aligning stakeholders’ interests, not just juggling them. It’s about building companies that leave the world a better place. Most of all, it’s about why you must do all this, or risk being left in the dust... and how to get there from wherever you are now.

Present Knowledge in Nutrition

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Publisher : Academic Press
ISBN 13 : 0128198427
Total Pages : 680 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Present Knowledge in Nutrition by : Bernadette P. Marriott

Download or read book Present Knowledge in Nutrition written by Bernadette P. Marriott and published by Academic Press. This book was released on 2020-07-21 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Present Knowledge in Nutrition: Basic Nutrition and Metabolism, Eleventh Edition, provides an accessible, referenced source on the most current information in the broad field of nutrition. Now broken into two volumes and updated to reflect scientific advancements since the publication of the last edition, the book includes expanded coverage on basic nutrition, metabolism and clinical and applied topics. This volume provides coverage of macronutrients, vitamins, minerals and other dietary components and concludes with new approaches in nutrition science that apply to many, if not all, of the nutrients and dietary components presented throughout the reference. Advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine and related fields will find this resource useful. In addition, professionals in academia and medicine, including clinicians, dietitians, physicians, health professionals, academics and industrial and government researchers will find the content extremely useful. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/). Provides an accessible source of the most current, reliable and comprehensive information in the broad field of nutrition Features new chapters on topics of emerging importance, including the microbiome, eating disorders, nutrition in extreme environments, and the role of nutrition and cognition in mental status Covers topics of clinical relevance, including the role of nutrition in cancer support, ICU nutrition, supporting patients with burns, and wasting, deconditioning and hypermetabolic conditions

Innovative Medicine

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Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

The Third Wave

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Publisher : Random House
ISBN 13 : 0679604928
Total Pages : 242 pages
Book Rating : 4.6/5 (796 download)

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Book Synopsis The Third Wave by : Alison Thompson

Download or read book The Third Wave written by Alison Thompson and published by Random House. This book was released on 2011-07-12 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alison Thompson, a filmmaker living in New York City, was enjoying Christmas with her boyfriend in 2004 when she saw the news reports online: a 9.3 magnitude earthquake had struck the sea near Indonesia, triggering a massive tsunami that hit much of southern Asia. As she watched the death toll climb, Thompson had one thought: She had to go help. A few years earlier, she had spent eight months volunteering at Ground Zero after 9/11. She’d learned then that when disaster strikes, it’s not just the firemen and Red Cross who are needed—every single person can make a difference. With $300 in cash, some basic medical supplies, and a vague idea that she’d go wherever she was needed, Thompson headed to Sri Lanka. Along with a small team of volunteers, she settled in a coastal town that had been hit especially hard and began tending to people’s injuries, giving out food and water, playing games with the children, collecting dead bodies, and helping rebuild the local school and homes that had been destroyed. Thompson had intended to stay for two weeks; she ended up staying for fourteen months. She and her team helped start new businesses and set up the first tsunami early-warning center in Sri Lanka, which continues to save lives today. The Third Wave tells the inspiring story of how volunteering changed Thompson’s life. It begins with her first real introduction to disaster relief after 9/11 and ends with her more recent efforts in Haiti, where she has helped create and run, with Sean Penn, an internally-displaced-person camp and field hospital for more than 65,000 Haitians who lost their homes in the 2010 earthquake. In The Third Wave, Thompson provides an invaluable inside glimpse into what really happens on the ground after a disaster—and a road map for what anyone can do to help. As Alison Thompson shows, with some resilience, a healthy sense of humor, and the desire to make a difference, we all have what it takes to change the world for the better.

Running with My Pants Down

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Author :
Publisher : iUniverse
ISBN 13 : 1462021743
Total Pages : 486 pages
Book Rating : 4.4/5 (62 download)

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Book Synopsis Running with My Pants Down by : JIM CUBA

Download or read book Running with My Pants Down written by JIM CUBA and published by iUniverse. This book was released on 2011-08-12 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Running with my pants down is a perfect metaphor for the life of one Logan Hunter. Emotionally scarred by the faith forced on him by the traditions of his wildly dysfunctional Catholic-centric family, Logan sets out to blaze his own trail. After a young marriage that everyone knew was doomed to failure, he moves on at a breakneck pace to drink in all that life has to offer, literally and figuratively. His life becomes ruled by the three Bs: business, bed-hopping, and booze. Somewhere along the way, he meets Misty, the sex kitten; Kat, the young, unpredictable one; Liz, the cougar with a voracious appetite for younger men; Champagne Washington, the sultry nightclub singer; Connie and Amanda, the gorgeous, sophisticated, and carnally experimental women who give him a night hell never forget; The Wild ThingsDelta Sue, Kitten, and Lola; and the always-intoxicating Spanish beauty, Carmen. Could there be more? In an ironic twist of fate, Logans best friend, Eddie, starts down an unexpected, life-altering path that begins to mirror Logans. Neither could predict just how a couple of chance meetings would change the game for each of them.

Astrology Uncut

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Author :
Publisher : One World
ISBN 13 : 9780812967937
Total Pages : 0 pages
Book Rating : 4.9/5 (679 download)

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Book Synopsis Astrology Uncut by : Rob Marriott

Download or read book Astrology Uncut written by Rob Marriott and published by One World. This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: ""The wait is over. Astrology "Uncut" is heah to provide salvation to the confused, wayward, and game-deprived. Now let us bow our heads and read. . . ." With "Astrology "Uncut, the language of the stars meets the code of the streets, the zodiac goes gangsta, and you find out how the day you were born makes you Superfly or Superfreak. Whether you're a schizophrenic Scorpio like Ol' Dirty Bastard, Capricorn cool like Mary J. Blige, or a prideful Leo cat like Jennifer Lopez, this post-hiphop manifesto dishes out the good, the bad, and everything in between--from why you gossip so damn much (communication rules Geminis!) to why you are likely to cry while watching Oprah (sensitive Cancers). You will also discover your sign's - booty rating (none, onion, or badoonkadoonk?) - worst-case scenario (Virgo: postsurgery Michael Jackson; Aries: Suge Knight?) - favorite accessory (mirror or money counter?) - erogenous zone (your office or your mama's bed?) - mix tape (music by and for cats under their sun sign) - moment (Capricorn Frazier knocking out Capricorn Ali or Libran Cochran rhyming in the courtroom?) Written by former editors of "The Source and "Honey, this is the no-holds-barred astrological guide to ghettobility--a combination of mental fitness, trifeness, and street smarts. It tells you the real deal on your sign's personality in a way that no other astrology book can.

Life... Don't Miss It. I Almost Did.: How I Learned to Live Life to the Fullest

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Author :
Publisher :
ISBN 13 : 9781599322698
Total Pages : 0 pages
Book Rating : 4.3/5 (226 download)

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Book Synopsis Life... Don't Miss It. I Almost Did.: How I Learned to Live Life to the Fullest by : Gary Kunath

Download or read book Life... Don't Miss It. I Almost Did.: How I Learned to Live Life to the Fullest written by Gary Kunath and published by . This book was released on 2011-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some say I am a lucky guy, because I figured it out before it was too late. I figured out what truly matters in life and I live my life by those principles. I almost missed out. I allowed myself to get caught up in life's spin cycle. Too much work, allowing things that ultimately meant nothing to consume my life, being too busy to savor the simple things in life, thinking net worth was the true goal...well, not anymore. As I look around, what amazes me is that everybody wants the same things: We want to be happy, get out of the rat race, enjoy life, have fun, persevere through adversity, maximize joy, take risks, and be proud of who we are, what we have accomplished and the legacy we will leave. I know that because in my 30-year career as a sales executive, entrepreneur, public speaker, and faculty member at top companies and business schools, I have seen it with my own eyes. I have engaged with literally thousands of people of all ages, all over the world. They all want life worth. They want joy and contentment with their lives. They know they need it, they just don't know how to get it. I do. I did it. I am a lucky guy because I figured it out at an age when I could apply it. It wasn't too late. And it is also surprisingly simple, if you know the secrets. The purpose of this book is to share with people of all ages the secrets to achieving a high life worth at any age. Life is too awesome to not be enjoyed every day in every way. It can be done. I know, because I am living it.

Cell Culture Engineering

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Author :
Publisher : Springer
ISBN 13 : 3540340076
Total Pages : 179 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Cell Culture Engineering by : Wei-Shu Hu

Download or read book Cell Culture Engineering written by Wei-Shu Hu and published by Springer. This book was released on 2006-08-16 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.