The Kinetochore

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The Kinetochore:

Author : Peter De Wulf
Publisher : Springer Science & Business Media
ISBN 13 : 038769076X
Total Pages : 516 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis The Kinetochore: by : Peter De Wulf

Download or read book The Kinetochore: written by Peter De Wulf and published by Springer Science & Business Media. This book was released on 2008-12-16 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.

Centromeres and Kinetochores

Author : Ben E. Black
Publisher : Springer
ISBN 13 : 3319585924
Total Pages : 554 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Centromeres and Kinetochores by : Ben E. Black

Download or read book Centromeres and Kinetochores written by Ben E. Black and published by Springer. This book was released on 2017-08-23 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring. The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as well as those already acquainted with the field.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cells: Molecules and Mechanisms

Author : Eric Wong
Publisher : Axolotl Academic Publishing
ISBN 13 : 0985226110
Total Pages : 283 pages
Book Rating : 4.9/5 (852 download)

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Book Synopsis Cells: Molecules and Mechanisms by : Eric Wong

Download or read book Cells: Molecules and Mechanisms written by Eric Wong and published by Axolotl Academic Publishing. This book was released on 2009 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Concepts of Biology

Author : Samantha Fowler
Publisher :
ISBN 13 : 9789888407453
Total Pages : 618 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Concepts of Biology by : Samantha Fowler

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Aneuploidy

Author : Vicki Dellarco
Publisher : Springer Science & Business Media
ISBN 13 : 1461321271
Total Pages : 557 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Aneuploidy by : Vicki Dellarco

Download or read book Aneuploidy written by Vicki Dellarco and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "Symposium on Aneuploidy: Etiology and Mechanisms" was held at the Carnegie Institution of Washington Auditorium from March 25-29. 1985. This Symposium developed as a consequence of the concern of the Environmen tal Protection Agency with the support of the National Institute of Envi ronmental Health Sciences about human exposure to environmental agents that cause aneuploidy. The program was chosen to explore what is currently known about the underlying causes, the origins, and the extent of the prob lem of human aneuploidy, and whether exposure to environmental agents is assodated with an increased incidence of aneuploidy in humans. Basic research findings in the area of mitosis and meiosis were presented and related to possible mechanisms of how aneuploidy may be produced spontane ously and chemically. A survey of data regarding the chemical induction of aneuploidy in experimental organisms was presented. Outstanding scientists from different fields were invited to cover a broad perspective of aneu ploidy from the molecular aspects to the human situation. We hope that the publication of the proceedings will share the enthu siasm of the meeting and its scientific content. The topic of aneuploidy has received little attention and it is the purpose of this Volume to establish a scientific basis for assessing health risks posed by environ mental exposures to aneuploidy-inducing chemicals. Vicki L. DeJlarco Peter E. Voytek Alexander Hollaender vii ACKNOWLEDGEMENT The Editors of the proceedings of the "Symposium on Aneuploidy" wish to acknowledge the support of Dr. Elizabeth L.

Quantitative Imaging in Cell Biology

Author :
Publisher : Academic Press
ISBN 13 : 0124202012
Total Pages : 588 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis Quantitative Imaging in Cell Biology by :

Download or read book Quantitative Imaging in Cell Biology written by and published by Academic Press. This book was released on 2014-06-25 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Centromere

Author : Durdica Ugarkovic
Publisher : Springer Science & Business Media
ISBN 13 : 3642001823
Total Pages : 191 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Centromere by : Durdica Ugarkovic

Download or read book Centromere written by Durdica Ugarkovic and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The centromere is a chromosomal region that enables the accurate segregation of chromosomes during mitosis and meiosis. It holds sister chromatids together, and through its centromere DNA–protein complex known as the kinetochore binds spindle microtubules to bring about accurate chromosome movements. Despite this conserved function, centromeres exhibit dramatic difference in structure, size, and complexity. Extensive studies on centromeric DNA revealed its rapid evolution resulting often in significant difference even among closely related species. Such a plasticity of centromeric DNA could be explained by epigenetic c- trol of centromere function, which does not depend absolutely on primary DNA sequence. According to epigenetic centromere concept, which is thoroughly d- cussed by Tanya Panchenko and Ben Black in Chap. 1 of this book, centromere activation or inactivation might be caused by modifications of chromatin. Such acquired chromatin epigenetic modifications are then inherited from one cell di- sion to the next. Concerning centromere-specific chromatin modification, it is now evident that all centromeres contain a centromere specific histone H3 variant, CenH3, which replaces histone H3 in centromeric nucleosomes and provides a structural basis that epigenetically defines centromere and differentiates it from the surrounding chromatin. Recent insights into the CenH3 presented in this chapter add important mechanistic understanding of how centromere identity is initially established and subsequently maintained in every cell cycle.

Mitosis and Meiosis

Author :
Publisher : Academic Press
ISBN 13 : 9780080859590
Total Pages : 489 pages
Book Rating : 4.8/5 (595 download)

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Book Synopsis Mitosis and Meiosis by :

Download or read book Mitosis and Meiosis written by and published by Academic Press. This book was released on 1998-12-16 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitosis and Meiosis details the wide variety of methods currently used to study how cells divide as yeast and insect spermatocytes, higher plants, and sea urchin zygotes. With chapters covering micromanipulation of chromosomes and making, expressing, and imaging GFP-fusion proteins, this volume contains state-of-the-art "how to" secrets that allow researchers to obtain novel information on the biology of centrosomes and kinetochores and how these organelles interact to form the spindle. Chapters Contain Information On: * How to generate, screen, and study mutants of mitosis in yeast, fungi, and flies * Techniques to best image fluorescent and nonfluorescent tagged dividing cells * The use and action of mitoclastic drugs * How to generate antibodies to mitotic components and inject them into cells * Methods that can also be used to obtain information on cellular processes in nondividing cells

Cells

Author : Benjamin Lewin
Publisher : Jones & Bartlett Learning
ISBN 13 : 9780763739058
Total Pages : 918 pages
Book Rating : 4.7/5 (39 download)

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Book Synopsis Cells by : Benjamin Lewin

Download or read book Cells written by Benjamin Lewin and published by Jones & Bartlett Learning. This book was released on 2007 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: "CELLS, the most cutting-edge textbook in the field, is the ideal resource for advanced undergraduate and graduate students entering the world of cell biology, and is a useful tool for scientists who wish to learn more about topics outside their field. This important new text provides full coverage of the structure, organization, growth, regulation, movements, and interaction of cells, with an emphasis on eukaryotic cells. Where they are known, the molecular bases for human diseases are discussed in each chapter.Under the direction of Dr. Benjamin Lewin and three expert lead editors, each chapter was prepared by top scientists who specialize in the subject area. All chapters were carefully edited to maintain consistent use of terminology and to achieve a homogeneous level of detail and rigor."--Publisher's website.

International Review of Cytology

Author :
Publisher : Academic Press
ISBN 13 : 9780080586168
Total Pages : 327 pages
Book Rating : 4.5/5 (861 download)

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Book Synopsis International Review of Cytology by :

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1983-01-07 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology

Lewin's CELLS

Author : Lynne Cassimeris
Publisher : Jones & Bartlett Learning
ISBN 13 : 076376664X
Total Pages : 1079 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Lewin's CELLS by : Lynne Cassimeris

Download or read book Lewin's CELLS written by Lynne Cassimeris and published by Jones & Bartlett Learning. This book was released on 2011-03-25 with total page 1079 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated to incorporate the latest data in the field, Lewin's CELLS, Second Edition is the ideal resource for advanced undergraduate and graduate students entering the world of cell biology. Redesigned to incorporate new learning tools and elements, this edition continues to provide readers with current coverage of the structure, organization, growth, regulation, movements, and interaction of cells, with an emphasis on eukaryotic cells. Under the direction of three expert lead editors, new chapters on metabolism and general molecular biology have been added by subject specialist. All chapters have been carefully edited to maintain consistent use of terminology and to achieve a homogenous level of detail and rigor. A new design incorporates many new pedagogical elements, including Concept & Reasoning Questions, Methods boxes, Clinical Applications boxes, and more.

Muscle Contraction and Cell Motility

Author : H. Sugi
Publisher : Springer Science & Business Media
ISBN 13 : 3642769276
Total Pages : 276 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Muscle Contraction and Cell Motility by : H. Sugi

Download or read book Muscle Contraction and Cell Motility written by H. Sugi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume intends to provide a comprehensive overview on the mecha nisms of muscle contraction and non-muscle cell motility at the molecu lar and cellular level, not only for investigators in these fields but also for general readers interested in these topics. A most attractive feature of various living organisms in the animal and plant kingdoms is their ability to move. In spite of a great diversity in the structure and function of various motile systems, it has frequently been assumed since the nineteenth century that all kinds of "motility" are essentially the same. Based on this assumption, some investigators in the nineteenth century thought that the mechanisms of motility could better be studied on primitive non-muscle motile systems such as amoeboid movement, rath er than on highly specialized muscle cells. Contrary to their expectation, however, the basic mechanisms of motility have been revealed solely by investigations on vertebrate skeletal muscles, since a monumental discovery of Szent-Gyorgyi and his coworkers in the early 1940s that muscle contraction results from the interaction between two different contractile proteins, actin and myosin, coupled with ATP hydrolysis.

Histology and Cell Biology: An Introduction to Pathology E-Book

Author : Abraham L Kierszenbaum
Publisher : Elsevier Health Sciences
ISBN 13 : 0323085881
Total Pages : 719 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Histology and Cell Biology: An Introduction to Pathology E-Book by : Abraham L Kierszenbaum

Download or read book Histology and Cell Biology: An Introduction to Pathology E-Book written by Abraham L Kierszenbaum and published by Elsevier Health Sciences. This book was released on 2011-04-12 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histology and Cell Biology: An Introduction to Pathology uses a wealth of vivid, full-color images to help you master histology and cell biology. Dr. Abraham L. Kierszenbaum presents an integrated approach that correlates normal histology with cellular and molecular biology, pathology, and clinical medicine throughout the text. A unique pictorial approach—through illustrative diagrams, photomicrographs, and pathology photographs—paired with bolded words, key clinical terms in red, and clinical boxes and "Essential Concepts" boxes that summarize important facts give you everything you need to prepare for your course exams as well as the USMLE Step 1. Access to studentconsult.com, with USMLE-style multiple-choice review questions, downloadable images, and online only references. Easily find and cross-reference information through a detailed table of contents that highlights clinical examples in red. Review material quickly using pedagogical features, such as Essential Concept boxes, bolded words, and key clinical terms marked in red, that emphasize key details and reinforce your learning. Integrate cell biology and histology with pathology thanks to vivid descriptive illustrations that compare micrographs with diagrams and pathological images. Apply the latest developments in pathology through updated text and new illustrations that emphasize appropriate correlations. Expand your understanding of clinical applications with additional clinical case boxes that focus on applying cell and molecular biology to clinical conditions. Effectively review concepts and reinforce your learning using new Concept Map flow charts that provide a framework to illustrate the integration of cell-tissue-structure-function within a clinical-pathology context.

Centrosome and Centriole

Author :
Publisher : Academic Press
ISBN 13 : 0128026383
Total Pages : 434 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Centrosome and Centriole by :

Download or read book Centrosome and Centriole written by and published by Academic Press. This book was released on 2015-09-10 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Cell Biology looks at methods for analyzing centrosomes and centrioles. Chapters cover such topics as methods to analyze centrosomes, centriole biogenesis and function in multi-ciliated cells, laser manipulation of centrosomes or CLEM, analysis of centrosomes in human cancers and tissues, proximity interaction techniques to study centrosomes, and genome engineering for creating conditional alleles in human cells. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Plant Cell Biology

Author : Randy O. Wayne
Publisher : Academic Press
ISBN 13 : 0080921272
Total Pages : 408 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Plant Cell Biology by : Randy O. Wayne

Download or read book Plant Cell Biology written by Randy O. Wayne and published by Academic Press. This book was released on 2009-09-15 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Cell Biology is a semester long course for undergraduates and graduate students which integrates mathematics and physics, two years of chemistry, genetics, biochemistry and evolution disciplines. Having taught this course for over ten years, the author uses his expertise to relate the background established in plant anatomy, plant physiology, plant growth and development, plant taxonomy, plant biochemistry, and plant molecular biology courses to plant cell biology. This integration attempts to break down the barrier so plant cell biology is seen as an entrée into higher science. Distinguishing this book from papers that are often used for teaching the subject which use a single plant to demonstrate the techniques of molecular biology, this book covers all aspects of plant cell biology without emphasizing any one plant, organelle, molecule, or technique. Although most examples are biased towards plants, basic similarities between all living eukaryotic cells (animal and plant) are recognized and used to best illustrate for students cell processes. Thoroughly explains the physiological underpinnings of biological processes to bring original insight related to plants Includes examples throughout from physics, chemistry, geology, and biology to bring understanding to plant cell development, growth, chemistry and diseases Provides the essential tools for students to be able to evaluate and assess the mechanisms involved in cell growth, chromosome motion, membrane trafficking, and energy exchange Companion Web site provides support for all plant cell biology courses

Structure and Assembly

Author : J.E. Hesketh
Publisher : Elsevier
ISBN 13 : 9780080541891
Total Pages : 307 pages
Book Rating : 4.5/5 (418 download)

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Book Synopsis Structure and Assembly by : J.E. Hesketh

Download or read book Structure and Assembly written by J.E. Hesketh and published by Elsevier. This book was released on 1995-11-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the treatise deals with structural aspects of the cytoskeleton: the characteristics of the filaments and their components; the organization of the genes; motor proteins; interactions with membranes.