The Impact Of Immunosenescence And Senescence Of Immune Cells On Responses To Infection And Vaccination

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Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Handbook on Immunosenescence

Author : Tamas Fulop
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Molecular Basis of Nutrition and Aging

Author : Marco Malavolta
Publisher : Academic Press
ISBN 13 : 0128018275
Total Pages : 786 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular Basis of Nutrition and Aging by : Marco Malavolta

Download or read book Molecular Basis of Nutrition and Aging written by Marco Malavolta and published by Academic Press. This book was released on 2016-04-15 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. - Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging - Explores how nutritional factors are involved in the pathogenesis of aging across body systems - Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition

The Impact of Immunosenescence and Senescence of Immune Cells on Responses to Infection and Vaccination

Author : Birgit Weinberger
Publisher : Frontiers Media SA
ISBN 13 : 2889763110
Total Pages : 135 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Impact of Immunosenescence and Senescence of Immune Cells on Responses to Infection and Vaccination by : Birgit Weinberger

Download or read book The Impact of Immunosenescence and Senescence of Immune Cells on Responses to Infection and Vaccination written by Birgit Weinberger and published by Frontiers Media SA. This book was released on 2022-12-14 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Frontiers in Cognitive Aging

Author : Roger A. Dixon
Publisher : Oxford : Oxford University Press
ISBN 13 : 9780198525691
Total Pages : 390 pages
Book Rating : 4.5/5 (256 download)

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Book Synopsis New Frontiers in Cognitive Aging by : Roger A. Dixon

Download or read book New Frontiers in Cognitive Aging written by Roger A. Dixon and published by Oxford : Oxford University Press. This book was released on 2004 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an ever increasing population of aging people in the western world, it is more crucial than ever that we try to understand how and why cognitive competence breaks down with advancing age; why do some people follow normal patterns of cognitive change, while others follow a path of progressive decline, with neurodegenerative diseases such as Alzheimer's. What can be done to prevent cognitive decline - or to avoid neurodegenerative diseases? The answers, if they come, will not emerge from research within one discipline, but from work being done across a range of scientific and medical specialities. This volume brings together leading experts from a range of fields studying cognitive aging, including neuroscience, pharmacology, health, genetics, sensory biology, and epidemiology. Unlike other books in this area, this book is more about 'new frontiers' than past research and accomplishments. Recently cognitive aging research has taken several new directions, linking with, and benefiting from, rapid technological and theoretical advances in these neighbouring disciplines. This book provides unique interdisciplinary coverage of the topic. With each chapter including commentaries from specialists in related fields, the book provides an integrative study of the topic. For those within the fields of psychology, cognitive neuroscience, and geriatrics, this volume will make an important contribution in furthering our understanding of a problem that affects us all.

Inflammation, Advancing Age and Nutrition

Author : Irfan Rahman
Publisher : Academic Press
ISBN 13 : 0123978076
Total Pages : 383 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Inflammation, Advancing Age and Nutrition by : Irfan Rahman

Download or read book Inflammation, Advancing Age and Nutrition written by Irfan Rahman and published by Academic Press. This book was released on 2013-09-03 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. - Includes models of aging, including worm, mouse and human - Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health - Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition - Includes suggested nutritional interventions

Encyclopedia of Gerontology and Population Aging

Author : Danan Gu
Publisher : Springer
ISBN 13 : 9783030220082
Total Pages : 5507 pages
Book Rating : 4.2/5 (2 download)

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Book Synopsis Encyclopedia of Gerontology and Population Aging by : Danan Gu

Download or read book Encyclopedia of Gerontology and Population Aging written by Danan Gu and published by Springer. This book was released on 2021-11-03 with total page 5507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eight-volume encyclopedia brings together a comprehensive collection of work highlighting established research and emerging science in all relevant disciplines in gerontology and population aging. It covers the breadth of the field, gives readers access to all major sub-fields, and illustrates their interconnectedness with other disciplines. With more than 1300 cross-disciplinary contributors—including anthropologists, biologists, economists, psychiatrists, public policy experts, sociologists, and others—the encyclopedia delves deep into key areas of gerontology and population aging such as ageism, biodemography, disablement, longevity, long-term care, and much more. Paying careful attention to empirical research and literature from around the globe, the encyclopedia is of interest to a wide audience that includes researchers, teachers and students, policy makers, (non)governmental agencies, public health practitioners, business planners, and many other individuals and organizations.

Handbook of Human Stress and Immunity

Author : Ronald Glaser
Publisher : Academic Press
ISBN 13 : 1483295125
Total Pages : 436 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Handbook of Human Stress and Immunity by : Ronald Glaser

Download or read book Handbook of Human Stress and Immunity written by Ronald Glaser and published by Academic Press. This book was released on 2014-06-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.

Aging

Author : L. Robert
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026530
Total Pages : 226 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Aging by : L. Robert

Download or read book Aging written by L. Robert and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging inspired a large number of theories trying to rationalize the aging process common to all living beings. In this publication the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are reviewed. Furthermore theoretical and experimental evidence of the most important theoretical elements based on Darwinian evolution, cellular aging, role of cell membranes, free radicals and oxidative processes, receptor-mediated reactions, the extracellular matrix and immune functions as well as the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are discussed. These presentations of theories and related experimental facts give a global overview of up to date concepts of the biology of the aging process and are of essential reading not only for specialists in this field but also for practitioners of scientific, medical, social and experimental sciences.

Geriatric Oncology

Author : Martine Extermann
Publisher : Springer
ISBN 13 : 9783319574141
Total Pages : 1150 pages
Book Rating : 4.5/5 (741 download)

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Book Synopsis Geriatric Oncology by : Martine Extermann

Download or read book Geriatric Oncology written by Martine Extermann and published by Springer. This book was released on 2020-01-30 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as a comprehensive resource for clinicians and researchers seeking in-depth information on geriatric oncology. The coverage encompasses epidemiology, the biology and (patho)physiology of aging and cancer, geriatric assessment and management, hematologic malignancies, solid tumors, issues in patient care, and research methods. Since cancer is a disease of aging and people are living longer, most cancer patients are now aged 70 and older. Yet the more we age, the more diverse we become in terms of our health, biologic fitness, and cancer behavior. Typically, however, general oncology clinical trials address only a selected healthier and younger population of patients. Geriatric oncology is the area of oncology that addresses these issues but while a wealth of knowledge has been accumulated, information is often difficult to retrieve or insufficiently detailed. The SpringerReference program, in which this book is published, offers an ideal format for overcoming these limitations since it combines thorough coverage with access to living editions constantly updated chapter by chapter via a dynamic peer-review process, ensuring that information remains current and pertinent.

The Cambridge Handbook of Successful Aging

Author : Rocío Fernández-Ballesteros
Publisher : Cambridge University Press
ISBN 13 : 1108641431
Total Pages : 969 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis The Cambridge Handbook of Successful Aging by : Rocío Fernández-Ballesteros

Download or read book The Cambridge Handbook of Successful Aging written by Rocío Fernández-Ballesteros and published by Cambridge University Press. This book was released on 2019-01-24 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.

Trained Immunity-based Vaccines

Author : Jose Luis Subiza
Publisher : Frontiers Media SA
ISBN 13 : 2889712311
Total Pages : 195 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Trained Immunity-based Vaccines by : Jose Luis Subiza

Download or read book Trained Immunity-based Vaccines written by Jose Luis Subiza and published by Frontiers Media SA. This book was released on 2021-08-25 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Immunology of Aging

Author : Ahmad Massoud
Publisher : Springer Science & Business Media
ISBN 13 : 3642394957
Total Pages : 411 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Immunology of Aging by : Ahmad Massoud

Download or read book Immunology of Aging written by Ahmad Massoud and published by Springer Science & Business Media. This book was released on 2013-11-29 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.

Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan

Author : Annibale Puca
Publisher : MDPI
ISBN 13 : 3036509801
Total Pages : 204 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan by : Annibale Puca

Download or read book Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan written by Annibale Puca and published by MDPI. This book was released on 2021-06-15 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.

Aging

Author : Stuart Jay Olshansky
Publisher :
ISBN 13 : 9781621820802
Total Pages : 0 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Aging by : Stuart Jay Olshansky

Download or read book Aging written by Stuart Jay Olshansky and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Aging affects us all and is characterized not only by increasing frailty but by increased susceptibility to conditions such as Alzheimer's, cardiovascular disease, and cancer. We are gaining an increasing understanding of the molecular mechanisms underlying aging, however, and uncovering clues to how life may be prolonged. This book examines the biological basis of aging and research into strategies that may extend lifespan"--

Oxford Textbook of Geriatric Medicine

Author : Jean-Pierre Michel
Publisher : Oxford University Press
ISBN 13 : 0198701594
Total Pages : 1393 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Oxford Textbook of Geriatric Medicine by : Jean-Pierre Michel

Download or read book Oxford Textbook of Geriatric Medicine written by Jean-Pierre Michel and published by Oxford University Press. This book was released on 2018 with total page 1393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the definitive international reference book on all aspects of the medical care of older persons will provide every physician involved in the care of older patients with a comprehensive resource on all the clinical problems they are likely to encounter, as well as on related psychological, philosophical, and social issues.

Innovation in Vaccinology

Author : Selene Baschieri
Publisher : Springer Science & Business Media
ISBN 13 : 9400745435
Total Pages : 294 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Innovation in Vaccinology by : Selene Baschieri

Download or read book Innovation in Vaccinology written by Selene Baschieri and published by Springer Science & Business Media. This book was released on 2012-07-20 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may raise safety concerns. The aim of this book is to provide an overview of some of the technology platforms that have been realized or are currently under development to try to address unsolved and new issues in the field of vaccine development. Common denominator of all thematic areas described herein is the multidisciplinary teamwork. Most of the enabling technologies have been established by putting in the “melting pot” expertise in fields that, at first glance, may appear very far apart. I hope that this collection of articles will make the readers aware that vaccinology is rapidly taking a new direction, ceasing to be an empirical science.