The Immunogenetics Of Chronic Inflammatory And Autoimmune Disease

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Mosaic of Autoimmunity

Author : Carlo Perricone
Publisher : Academic Press
ISBN 13 : 012814307X
Total Pages : 728 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mosaic of Autoimmunity by : Carlo Perricone

Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-13 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

Immunogenetics: A Molecular and Clinical Overview

Author : Muneeb U Rehman
Publisher : Academic Press
ISBN 13 : 0323903355
Total Pages : 412 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Immunogenetics: A Molecular and Clinical Overview by : Muneeb U Rehman

Download or read book Immunogenetics: A Molecular and Clinical Overview written by Muneeb U Rehman and published by Academic Press. This book was released on 2021-11-30 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. - Contains exclusive information about research on immunogenetics from around the globe - Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications - Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Genetic Predisposition to Disease

Author : Sara L. Torres
Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Genetic Predisposition to Disease by : Sara L. Torres

Download or read book Genetic Predisposition to Disease written by Sara L. Torres and published by . This book was released on 2008 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A genetic predisposition is a genetic effect which influences the phenotype of an organism but which can be modified by the environmental conditions. Genetic testing is able to identify individuals who are genetically predisposed to certain health problems such as cancer or other life altering diseases. This book discusses the determination of the genetic basis of health problems that will help the precise mechanisms of health problem such as a disease or physical disorder.

The Immunogenetics of Autoimmune Diseases

Author : Nadir R. Farid
Publisher : CRC Press
ISBN 13 : 9780849368981
Total Pages : 340 pages
Book Rating : 4.3/5 (689 download)

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Book Synopsis The Immunogenetics of Autoimmune Diseases by : Nadir R. Farid

Download or read book The Immunogenetics of Autoimmune Diseases written by Nadir R. Farid and published by CRC Press. This book was released on 1990-11-30 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex MHC; elucidation of its gene structure and polymorphism, as well as the molecular basis of MHC restriction; the arrangement, expression, and regulation of immunoglobulins; definition of the structure of the T cell receptor and organization of its genes; and the characterization of soluble factors involved in cell/cell interactions and cloning of their genes are among the major accomplishments. Volumes I and II build on these developments in basic immunology to introduce animal models of various diseases, corresponding human studies, and the genetic analysis of autoimmune traits at the patient population level. The book will be a tremendous asset to immunologists, geneticists, and physicians in various areas of clinical subspecialties.

IgG4-Related Sclerosing Cholangitis

Author : Terumi Kamisawa
Publisher : Springer
ISBN 13 : 9811045488
Total Pages : 141 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis IgG4-Related Sclerosing Cholangitis by : Terumi Kamisawa

Download or read book IgG4-Related Sclerosing Cholangitis written by Terumi Kamisawa and published by Springer. This book was released on 2018-07-31 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

Immunogenetics

Author :
Publisher : Springer
ISBN 13 : 9781617798436
Total Pages : 708 pages
Book Rating : 4.7/5 (984 download)

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Book Synopsis Immunogenetics by :

Download or read book Immunogenetics written by and published by Springer. This book was released on 2012-08-31 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cytokine Gene Polymorphisms in Multifactorial Conditions

Author : Koen Vandenbroeck
Publisher : CRC Press
ISBN 13 : 1420005324
Total Pages : 489 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Cytokine Gene Polymorphisms in Multifactorial Conditions by : Koen Vandenbroeck

Download or read book Cytokine Gene Polymorphisms in Multifactorial Conditions written by Koen Vandenbroeck and published by CRC Press. This book was released on 2006-06-21 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism

Autoimmune Liver Disease

Author : James Neuberger
Publisher : John Wiley & Sons
ISBN 13 : 1119532604
Total Pages : 336 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Autoimmune Liver Disease by : James Neuberger

Download or read book Autoimmune Liver Disease written by James Neuberger and published by John Wiley & Sons. This book was released on 2020-04-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein praxisorientierter Leitfaden zu autoimmunen Lebererkrankungen, Pathogenese, Diagnose und Management. Autoimmune Liver Disease Management and Clinical Practice erläutert alles Wissenswerte zum aktuellen Forschungsstand autoimmuner Lebererkrankungen und legt dabei den Schwerpunkt auf Diagnose und Behandlung. Nach einer ausführlichen Darstellung der heutigen Erkenntnisse in der Immunologie in Verbindung mit der Autoimmunität der Leber werden die vier wichtigsten autoimmunen Lebererkrankungen bei Erwachsenen und Kindern erläutert, einschließlich Management, Rolle von Lebertransplantationen, erprobte Ansätze des Patientenmanagements und Empowerment-Ansätze. Die Autoren, Experten des Fachgebiets, untersuchen im Detail autoimmune Lebererkrankungen und geben Kliniker Handreichungen zur Patientenunterstützung. Die folgenden Themenkomplexe werden unter anderem ausführlich behandelt: - Die vier autoimmunen Lebererkrankungen, deren Diagnose und Behandlungsoptionen. - Einsatz (und Missbrauch) von Autoantikörpern bei Diagnose und Behandlung. - Rolle und Zeitpunkt von Lebertransplantationen und die Auswirkung auf wiederkehrende autoimmune Lebererkrankungen und De-novo-Autoimmunhepatitis. - Optimales Patientenmanagement und patientenbezogene Pflege. Dieses Referenzwerk zeigt umfassend, im Detail und mit alltäglichem Praxisbezug die jüngsten Entwicklungen beim Management von Lebererkrankungen und richtet sich an Ärzte, Pflegepersonal und Experten im Gesundheitswesen.

Clinical and Basic Immunodermatology

Author : Anthony Gaspari
Publisher : Springer Science & Business Media
ISBN 13 : 1848001657
Total Pages : 812 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis Clinical and Basic Immunodermatology by : Anthony Gaspari

Download or read book Clinical and Basic Immunodermatology written by Anthony Gaspari and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatologists are being asked to understand the pathophysiology of a number of immune-mediated skin diseases. In addition, a number of new products have appeared on the market during the past decade which requires an understanding of the mechanisms of action of these drugs. Dermatologists, however, have no easily understood book to which they can refer to regarding the disease or the drug.

Autoimmune Disease Models

Author : Irun R. Cohen
Publisher : Academic Press
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Autoimmune Disease Models by : Irun R. Cohen

Download or read book Autoimmune Disease Models written by Irun R. Cohen and published by Academic Press. This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.

Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics

Author : Reed E. Pyeritz
Publisher : Elsevier
ISBN 13 : 0128152354
Total Pages : 1227 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics by : Reed E. Pyeritz

Download or read book Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics written by Reed E. Pyeritz and published by Elsevier. This book was released on 2024-10-23 with total page 1227 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world's most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for students, health providers, and researchers involved in the care of patients with genetic conditions, and increasingly, all areas of health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals related to the applications of medical genetics and genomics across the full spectrum of inherited disorders and applications to medicine more broadly. In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to developmental disorders, as well as genetic conditions that affect hearing and vision. Here genetic researchers, students, and health professionals will find new and fully revised chapters on human developmental genetics, disorders affecting craniofacial development, chromosomal abnormalities, including aneuploidies and structural abnormalities, hereditary hearing impairment, and various genetic conditions of the eye. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics, Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers. · Thoroughly introduces genetic researchers, students, and healthcare professionals to the principles of human developmental genetics · Examines a wide range of developmental disorders, including craniofacial development as well as disorders affecting hearing and vision · Includes color images supporting identification, concept illustration, and method processing · Features contributions by leading international researchers and practitioners of medical genetics

Immunogenetics of Autoimmune Disease

Author : Jorge R. Oksenberg
Publisher : Springer Science & Business Media
ISBN 13 : 0387399267
Total Pages : 168 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Immunogenetics of Autoimmune Disease by : Jorge R. Oksenberg

Download or read book Immunogenetics of Autoimmune Disease written by Jorge R. Oksenberg and published by Springer Science & Business Media. This book was released on 2007-12-22 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches.

SIDS Sudden Infant and Early Childhood Death

Author : Roger W. Byard
Publisher :
ISBN 13 : 9781925261677
Total Pages : 844 pages
Book Rating : 4.2/5 (616 download)

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Book Synopsis SIDS Sudden Infant and Early Childhood Death by : Roger W. Byard

Download or read book SIDS Sudden Infant and Early Childhood Death written by Roger W. Byard and published by . This book was released on 2018-04 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.

Autoimmune Endocrinopathies

Author : Robert Volpe
Publisher :
ISBN 13 : 9781475745719
Total Pages : 452 pages
Book Rating : 4.7/5 (457 download)

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Book Synopsis Autoimmune Endocrinopathies by : Robert Volpe

Download or read book Autoimmune Endocrinopathies written by Robert Volpe and published by . This book was released on 2014-01-15 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Periodontitis

Author : Pachiappan Arjunan
Publisher : BoD – Books on Demand
ISBN 13 : 9535136054
Total Pages : 200 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Periodontitis by : Pachiappan Arjunan

Download or read book Periodontitis written by Pachiappan Arjunan and published by BoD – Books on Demand. This book was released on 2017-11-15 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periodontitis - A Useful Reference is a comprehensive book compiled by a team of experts with the objective of providing an overview of the basic pathology of "periodontitis" and its implication on oral health and general systemic health. Periodontitis has become a global health burden in recent days. It is noteworthy that oral health is being considered as the mirror of general health and the study of oral-systemic health connections has advanced among scientists, clinicians, and the public as well. We wish the array of chapters that highlights the importance and impact of periodontal health could be a useful guide for the community of public, students, and clinicians.

Essentials of Genomic and Personalized Medicine

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0080958117
Total Pages : 851 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Essentials of Genomic and Personalized Medicine by : Geoffrey S. Ginsburg

Download or read book Essentials of Genomic and Personalized Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2009-10-02 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. - Full color throughout - Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field - Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practic - Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science

The Autoimmune Diseases

Author : Noel R. Rose
Publisher :
ISBN 13 :
Total Pages : 928 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Autoimmune Diseases by : Noel R. Rose

Download or read book The Autoimmune Diseases written by Noel R. Rose and published by . This book was released on 1998 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.