The Hippocampus From Cells To Systems

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The Hippocampus from Cells to Systems

Author : Deborah E. Hannula
Publisher : Springer
ISBN 13 : 3319504061
Total Pages : 587 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis The Hippocampus from Cells to Systems by : Deborah E. Hannula

Download or read book The Hippocampus from Cells to Systems written by Deborah E. Hannula and published by Springer. This book was released on 2017-03-01 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia. The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).

Brain Organization and Memory

Author : James L. McGaugh
Publisher : Oxford University Press
ISBN 13 : 0195360257
Total Pages : 428 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Brain Organization and Memory by : James L. McGaugh

Download or read book Brain Organization and Memory written by James L. McGaugh and published by Oxford University Press. This book was released on 1992-06-25 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume summarizes recent findings of leading researchers investigating the brain systems that underlie memory. The book reviews recent progress in understanding forms of memory in animals and humans and the interaction of cortical and subcortical systems in the regulation of memory. Special emphasis is given to the development of neural network models that attempt to link cells to systems in the representation of memory. The book will be an invaluable source for cognitive psychologists, neuroscientists, and students interested in this active and exciting area of research.

Discovering the Brain

Author : National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Micro-, Meso- and Macro-Dynamics of the Brain

Author : György Buzsáki
Publisher : Springer
ISBN 13 : 3319288024
Total Pages : 181 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Micro-, Meso- and Macro-Dynamics of the Brain by : György Buzsáki

Download or read book Micro-, Meso- and Macro-Dynamics of the Brain written by György Buzsáki and published by Springer. This book was released on 2016-05-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

Hippocampal Place Fields

Author : Sheri J.Y. Mizumori
Publisher : Oxford University Press
ISBN 13 : 0198043457
Total Pages : 431 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Hippocampal Place Fields by : Sheri J.Y. Mizumori

Download or read book Hippocampal Place Fields written by Sheri J.Y. Mizumori and published by Oxford University Press. This book was released on 2008-02-26 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function.

Space,Time and Memory in the Hippocampal Formation

Author : Dori Derdikman
Publisher : Springer
ISBN 13 : 3709112923
Total Pages : 567 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Space,Time and Memory in the Hippocampal Formation by : Dori Derdikman

Download or read book Space,Time and Memory in the Hippocampal Formation written by Dori Derdikman and published by Springer. This book was released on 2014-07-08 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation. The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.

The Hippocampus

Author : Robert Isaacson
Publisher : Springer
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis The Hippocampus by : Robert Isaacson

Download or read book The Hippocampus written by Robert Isaacson and published by Springer. This book was released on 1975 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: These books are the result of a conviction held by the editors, authors, and publisher that the time is appropriate for assembling in one place information about functions of the hippocampus derived from many varied lines of research. Because of the explosion of research into the anatomy, physiology, chemistry, and behavioral aspects of the hip pocampus, some means of synthesis of the results from these lines of research was called for. We first thought of a conference. In fact, officials in the National Institute of Mental Health suggested we organize such a conference on the hippocampus, but after a few tentative steps in this direction, interest at the federallevel waned, probably due to the decreases in federal support for research in the basic health sciences so keenly feit in recent years. However, the editors also had co me to the view that conferences are mainly valuabIe to the participants. The broad range of students (of all ages) of brain behavior relations do not profit from conference proceedings unless the proceedings are subsequently published. Furthermore, conferences dealing with the functional character of organ systems approached from many points of view are most successful after participants have become acquainted with each other's work. Therefore, we believe that a book is the best format for disseminating information, and that its publication can be the stimulus for many future conferences.

Neuronal Networks of the Hippocampus

Author : Roger D. Traub
Publisher : Cambridge University Press
ISBN 13 : 0521364817
Total Pages : 306 pages
Book Rating : 4.5/5 (213 download)

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Book Synopsis Neuronal Networks of the Hippocampus by : Roger D. Traub

Download or read book Neuronal Networks of the Hippocampus written by Roger D. Traub and published by Cambridge University Press. This book was released on 1991-05-31 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The questions of how a large population of neurons in the brain functions, how synchronized firing of neurons is achieved, and what factors regulate how many and which neurons fire under different conditions form the central theme of this book. Important neurological techniques for the physiological reconstruction of a large biological neural network are presented.

The Hippocampus

Author : Philippe Taupin
Publisher : Nova Publishers
ISBN 13 : 9781600219146
Total Pages : 156 pages
Book Rating : 4.2/5 (191 download)

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Book Synopsis The Hippocampus by : Philippe Taupin

Download or read book The Hippocampus written by Philippe Taupin and published by Nova Publishers. This book was released on 2007 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus , the Greek word for seahorse, is one of the most fascinating and intriguing regions of the mammalian brain. It is a bilateral incurved seahorse-shaped structure of the cerebral cortex. The hippocampus has a highly distinctive morphology. It is composed of two regions, the dentate gyrus (DG) and the Cornu Ammonis (CA). The nerve cells of the main layer of the DG and CA regions, the granule cells and pyramidal cells respectively, are organised in a tri-synaptic lamellaire circuit. The granule and pyramidal cells are glutamatergic excitatory. The granule cells elicit unique histological, biochemical, developmental, physio- and pathological features. The hippocampus is also an area of the brain that elicits a high degree of plasticity, like synaptic and phenotypic plasticity. It is also one of the few regions of the brain where neurogenesis, the generation of new nerve cells, occurs throughout adulthood. The hippocampus is involved in physio-and pathological processes, like learning and memory.

Memory Consolidation

Author : Herbert Weingartner
Publisher : Psychology Press
ISBN 13 : 9780898593235
Total Pages : 296 pages
Book Rating : 4.5/5 (932 download)

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Book Synopsis Memory Consolidation by : Herbert Weingartner

Download or read book Memory Consolidation written by Herbert Weingartner and published by Psychology Press. This book was released on 1984 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1984. Routledge is an imprint of Taylor & Francis, an informa company.

The Hippocampus Book

Author : Per Andersen
Publisher : Oxford University Press
ISBN 13 : 9780195100273
Total Pages : 892 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Beyond the Cognitive Map

Author : A. David Redish
Publisher : MIT Press
ISBN 13 : 9780262181945
Total Pages : 452 pages
Book Rating : 4.1/5 (819 download)

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Book Synopsis Beyond the Cognitive Map by : A. David Redish

Download or read book Beyond the Cognitive Map written by A. David Redish and published by MIT Press. This book was released on 1999 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are currently two major theories about the role of the hippocampus, a distinctive structure in the back of the temporal lobe. One says that it stores a cognitive map, the other that it is a key locus for the temporary storage of episodic memories. A. David Redish takes the approach that understanding the role of the hippocampus in space will make it possible to address its role in less easily quantifiable areas such as memory. Basing his investigation on the study of rodent navigation--one of the primary domains for understanding information processing in the brain--he places the hippocampus in its anatomical context as part of a greater functional system. Redish draws on the extensive experimental and theoretical work of the last 100 years to paint a coherent picture of rodent navigation. His presentation encompasses multiple levels of analysis, from single-unit recording results to behavioral tasks to computational modeling. From this foundation, he proposes a novel understanding of the role of the hippocampus in rodents that can shed light on the role of the hippocampus in primates, explaining data from primate studies and human neurology. The book will be of interest not only to neuroscientists and psychologists, but also to researchers in computer science, robotics, artificial intelligence, and artificial life.

The Hippocampus Book

Author : Per Andersen
Publisher : Oxford University Press
ISBN 13 : 0195100271
Total Pages : 853 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

The CA3 Region of the Hippocampus: How is it? What is it for? How does it do it?

Author : Enrico Cherubini
Publisher : Frontiers Media SA
ISBN 13 : 2889196313
Total Pages : 167 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis The CA3 Region of the Hippocampus: How is it? What is it for? How does it do it? by : Enrico Cherubini

Download or read book The CA3 Region of the Hippocampus: How is it? What is it for? How does it do it? written by Enrico Cherubini and published by Frontiers Media SA. This book was released on 2015-08-19 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CA3 hippocampal region receives information from the entorhinal cortex either directly from the perforant path or indirectly from the dentate gyrus via the mossy fibers (MFs). According to their specific targets (principal/mossy cells or interneurons), MFs terminate with large boutons or small filopodial extensions, respectively. MF-CA3 synapses are characterized by a low probability of release and pronounced frequency-dependent facilitation. In addition MF terminals are endowed with mGluRs that regulate their own release. We will describe the intrinsic membrane properties of pyramidal cells, which can sometimes fire in bursts, together with the geometry of their dendritic arborization. The single layer of pyramidal cells is quite distinct from the six-layered neocortical arrangement. The resulting aligned dendrites provides the substrate for laminated excitatory inputs. They also underlie a precise, diversity of inhibitory control which we will also describe in detail. The CA3 region has an especially rich internal connectivity, with recurrent excitatory and inhibitory loops. In recent years both in vivo and in vitro studies have allowed to better understand functional properties of the CA3 auto-associative network and its role in information processing. This circuit is implicated in encoding spatial representations and episodic memories. It generates physiological population synchronies, including gamma, theta and sharp-waves that are presumed to associate firing in selected assemblies of cells in different behavioral conditions. The CA3 region is susceptible to neurodegeneration during aging and after stresses such as infection or injury. Loss of some CA3 neurones has striking effects on mossy fiber inputs and can facilitate the generation of pathologic synchrony within the CA3 micro-circuit. The aim of this special topic is to bring together experts on the cellular and molecular mechanisms regulating the wiring properties of the CA3 hippocampal microcircuit in both physiological and pathological conditions, synaptic plasticity, behavior and cognition.We will particularly emphasize the dual glutamatergic and GABAergic phenotype of MF-CA3 synapses at early developmental stages and the steps that regulate the integration of newly generated neurons into the adult dentate gyrus-CA3 circuit.

Memory, Amnesia, and the Hippocampal System

Author : Neal J. Cohen
Publisher : MIT Press
ISBN 13 : 0262032031
Total Pages : 348 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Memory, Amnesia, and the Hippocampal System by : Neal J. Cohen

Download or read book Memory, Amnesia, and the Hippocampal System written by Neal J. Cohen and published by MIT Press. This book was released on 1993 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this text, Neal J. Cohen and Howard Eichenbaum bring together converging findings from neuropsychology, neuroscience and cognitive science that provide the critical clues and constraints for developing a more comprehensive understanding of memory. Specifically, they offer a cognitive neuroscience theory of memory that accounts for the nature of memory impairment exhibited in human amnesia and animal models of amnesia, that specifies the functional role played by the hippocampal system in memory, and that provides further understanding of the componential structure of memory.

The Memory System of the Brain

Author : J. Z. Young
Publisher : Univ of California Press
ISBN 13 : 0520373103
Total Pages : 136 pages
Book Rating : 4.5/5 (23 download)

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Book Synopsis The Memory System of the Brain by : J. Z. Young

Download or read book The Memory System of the Brain written by J. Z. Young and published by Univ of California Press. This book was released on 2022-08-19 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1966.

The Clinical Neurobiology of the Hippocampus

Author : Thorsten Bartsch
Publisher : OUP Oxford
ISBN 13 : 0191628964
Total Pages : 336 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis The Clinical Neurobiology of the Hippocampus by : Thorsten Bartsch

Download or read book The Clinical Neurobiology of the Hippocampus written by Thorsten Bartsch and published by OUP Oxford. This book was released on 2012-07-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of the most studied structures in the human brain and plays a pivotal role in human memory function. Its recognized function is reflected by the presence of an extensive body of neurophysiological, neuropsychological, anatomical and neurocomputational literature that presents basic mechanisms, theoretical models and psychological concepts. However, in the rapidly growing field of hippocampal research, the clinical aspects of diseases that affect the hippocampus are greatly under-represented in current literature, and clinical approaches and concepts are scattered throughout various clinical and basic scientific disciplines. The Clinical Neurobiology of the Hippocampus explores clinical approaches to the range of diseases that affect the hippocampus. It brings together and reviews the common methods, clinical findings, concepts, mechanisms and, where applicable, therapeutic strategies for these clinical approaches. The clinical spectrum of hippocampal dysfunction encompasses a wide range of neurological, behavioural and psychiatric symptoms and surpasses the ability to encode, store and retrieve information. The relevance of hippocampal involvement in clinical diseases goes beyond mere neuropsychological deficits and includes psychopathological states in various conditions, such as acute amnesic syndromes, Alzheimer's disease, temporal lobe epilepsy (TLE), sleep, stroke medicine, limbic encephalitis, neurodevelopmental disorders, stress- and trauma-related disorders, depression, and schizophrenia. The first part of the book covers the basic and integrative features of the hippocampus, such as the anatomy and imaging of this structure, and the basic mechanisms of hippocampal function, including the principles of hippocampus-dependent memory processing in amnesia and sleep, the mechanisms of vulnerability and adult neurogenesis as well as the effects of stress. The second part covers the various clinical manifestations in which the hippocampus is involved and in which the preceding basic mechanisms are reflected. Bringing together a broad team of experts on the basic and clinical aspects of the hippocampus, the book provides an integrative view of the hippocampus. It is invaluable for neurologists, neuroscientists, and psychiatrists, and will stimulate interdisciplinary discussions in clinical neuroscience.