The Experience Of Alzheimers Disease

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Alzheimer's Disease

Author : Ahmed Moustafa
Publisher : Academic Press
ISBN 13 : 0128213353
Total Pages : 254 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Alzheimer's Disease by : Ahmed Moustafa

Download or read book Alzheimer's Disease written by Ahmed Moustafa and published by Academic Press. This book was released on 2021-08-28 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 44 million people have Alzheimer’s or related dementia worldwide, according to the Alzheimer’s Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer’s and other forms of dementia. First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer’s disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer’s disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer’s diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer’s disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer’s disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients. Reviews recent developments of cognitive and clinical studies Covers factors underlying the transition from mild cognitive impairment to Alzheimer’s disease Discusses different neural biomarkers underlying the development and treatment of Alzheimer’s disease Provides a comparison of the effectiveness of various types of treatments

The Problem of Alzheimer's

Author : Jason Karlawish
Publisher : St. Martin's Press
ISBN 13 : 1250218748
Total Pages : 269 pages
Book Rating : 4.2/5 (52 download)

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Book Synopsis The Problem of Alzheimer's by : Jason Karlawish

Download or read book The Problem of Alzheimer's written by Jason Karlawish and published by St. Martin's Press. This book was released on 2021-02-23 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.

Reducing the Impact of Dementia in America

Author : National Academies of Sciences Engineering and Medicine
Publisher :
ISBN 13 : 9780309495035
Total Pages : pages
Book Rating : 4.4/5 (95 download)

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Book Synopsis Reducing the Impact of Dementia in America by : National Academies of Sciences Engineering and Medicine

Download or read book Reducing the Impact of Dementia in America written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-04-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.

The Experience of Alzheimer's Disease

Author : Steven R. Sabat
Publisher : Wiley-Blackwell
ISBN 13 : 9780631216650
Total Pages : 376 pages
Book Rating : 4.2/5 (166 download)

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Book Synopsis The Experience of Alzheimer's Disease by : Steven R. Sabat

Download or read book The Experience of Alzheimer's Disease written by Steven R. Sabat and published by Wiley-Blackwell. This book was released on 2001-06-08 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time when the incidence of Alzheimer's Disease is increasing dramatically, this accessible account revolutionises our stereotypes of Alzheimer's patients and their care.

Caring for a Person with Alzheimer's Disease: Your Easy -to-Use- Guide from the National Institute on Aging (Revised January 2019)

Author : National Institute on Aging
Publisher : Lulu.com
ISBN 13 : 0359588190
Total Pages : 106 pages
Book Rating : 4.3/5 (595 download)

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Book Synopsis Caring for a Person with Alzheimer's Disease: Your Easy -to-Use- Guide from the National Institute on Aging (Revised January 2019) by : National Institute on Aging

Download or read book Caring for a Person with Alzheimer's Disease: Your Easy -to-Use- Guide from the National Institute on Aging (Revised January 2019) written by National Institute on Aging and published by Lulu.com. This book was released on 2019-04-13 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The guide tells you how to: Understand how AD changes a person Learn how to cope with these changes Help family and friends understand AD Plan for the future Make your home safe for the person with AD Manage everyday activities like eating, bathing, dressing, and grooming Take care of yourself Get help with caregiving Find out about helpful resources, such as websites, support groups, government agencies, and adult day care programs Choose a full-time care facility for the person with AD if needed Learn about common behavior and medical problems of people with AD and some medicines that may help Cope with late-stage AD

Gentlecare

Author : Moyra Jones
Publisher : Hartley & Marks Publishers
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Gentlecare by : Moyra Jones

Download or read book Gentlecare written by Moyra Jones and published by Hartley & Marks Publishers. This book was released on 1999 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gentlecare offers a revolutionary new approach to Alzheimer's care. Author Moyra Jones' sensitive and insightful program for caring for those suffering from dementia emphasizes looking after the whole person; body, mind, and soul. She encourages healthcare providers of all kinds to move away from trying to modify behavior and to instead find ways to make the journey through Alzheimer's Disease less traumatic. Gentlecare covers every aspect of Alzheimer's caregiving from assessment to attitudes, and grooming to communication. It looks for ways to cherish the diminishing person and will be of profound interest to anyone affected by Alzheimer's disease, whether concerned professionals or family members of those afflicted.

How Not to Study a Disease

Author : Karl Herrup
Publisher : MIT Press
ISBN 13 : 0262546019
Total Pages : 269 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis How Not to Study a Disease by : Karl Herrup

Download or read book How Not to Study a Disease written by Karl Herrup and published by MIT Press. This book was released on 2023-03-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authority on Alzheimer's disease offers a history of past failures and a roadmap that points us in a new direction in our journey to a cure. For decades, some of our best and brightest medical scientists have dedicated themselves to finding a cure for Alzheimer's disease. What happened? Where is the cure? The biggest breakthroughs occurred twenty-five years ago, with little progress since. In How Not to Study a Disease, neurobiologist Karl Herrup explains why the Alzheimer's discoveries of the 1990s didn't bear fruit and maps a direction for future research. Herrup describes the research, explains what's taking so long, and offers an approach for resetting future research. Herrup offers a unique insider's perspective, describing the red flags that science ignored in the rush to find a cure. He is unsparing in calling out the stubbornness, greed, and bad advice that has hamstrung the field, but his final message is a largely optimistic one. Herrup presents a new and sweeping vision of the field that includes a redefinition of the disease and a fresh conceptualization of aging and dementia that asks us to imagine the brain as a series of interconnected "neighborhoods." He calls for changes in virtually every aspect of the Alzheimer's disease research effort, from the drug development process, to the mechanisms of support for basic research, to the often-overlooked role of the scientific media, and more. With How Not to Study a Disease, Herrup provides a roadmap that points us in a new direction in our journey to a cure for Alzheimer's.

The Person with Alzheimer's Disease

Author : Phyllis Braudy Harris
Publisher : JHU Press
ISBN 13 : 9780801868771
Total Pages : 336 pages
Book Rating : 4.8/5 (687 download)

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Book Synopsis The Person with Alzheimer's Disease by : Phyllis Braudy Harris

Download or read book The Person with Alzheimer's Disease written by Phyllis Braudy Harris and published by JHU Press. This book was released on 2002-06-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to provide a comprehensive look at what it's like to have dementia and the subjective experience of living with progressive memory loss. Few families are untouched by Alzheimer's disease or a related dementia. Moving accounts of what it is like to care for someone with this disease have already been published, as well as how-to books that offer caregivers advice and information on coping. But this book is the first to provide a comprehensive report of what it is like to have dementia oneself—the subjective experience of living with progressive memory loss. Each chapter discusses a different aspect of having dementia, from the initial assessment and diagnosis through placement in a nursing home. The discussions are grounded in qualitative research and case studies, which convey the variable and personal nature of the experience. They seek to help clinicians, researchers, students, and caregivers (both professionals and family members) understand the experience of dementia, and thereby to promote better caregiving through a person-centered approach. Contributors: Kathleen Kahn-Denis, Judson Retirement Community; Casey Durkin, a psychotherapist in Cleveland, Ohio; Jane Gilliard, Dementia Voice, UK; Phyllis Braudy Harris, John Carroll University; John Keady, University of Wales, UK; John Killick, University of Stirling, UK; Rebecca G. Logsdon, University of Washington; Charlie Murphy, University of Stirling, UK; Alison Phinney, University of British Columbia, Canada; Steven R. Sabat, Georgetown University; Dorothy Seman, Alzheimer's Family Care Center, Chicago; Lisa Snyder, University of California, San Diego; Jane Stansell, Alzheimer's Family Care Center, Chicago; Gloria Sterin, Shaker Heights, Ohio; Jon C. Stuckey, Messiah College; Robyn Yale, Consultant to the Alzheimer's Association, San Francisco; Rosalie Young, Wayne State University School of Medicine.

Alzheimer's Disease and Dementia

Author : Steven R. Sabat
Publisher : Oxford University Press
ISBN 13 : 0190603135
Total Pages : 273 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Alzheimer's Disease and Dementia by : Steven R. Sabat

Download or read book Alzheimer's Disease and Dementia written by Steven R. Sabat and published by Oxford University Press. This book was released on 2018-01-02 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's is swiftly on the rise: it is estimated that every 67 seconds, someone develops the disease. For many, the words "Alzheimer's disease" or "dementia" immediately denote severe mental loss and, perhaps, madness. Indeed, the vast majority of media coverage of Alzheimer's disease (AD) and other types of dementia focuses primarily on the losses experienced by people diagnosed and the terrible burden felt by care partners yearning for a "magic bullet" drug cure. Providing an accessible, question-and-answer-format primer on what touches so many lives, and yet so few of us understand, Alzheimer's Disease and Dementia: What Everyone Needs to Know® contributes what is urgently missing from public knowledge: unsparing investigation of their causes and manifestations, and focus on the strengths possessed by people diagnosed. Steven R. Sabat mines a large body of research to convey the genetic and biological aspects of Alzheimer's disease, its clinical history, and, most significantly, to reveal the subjective experience of those with Alzheimer's or dementia. By clarifying the terms surrounding dementia and Alzheimer's, which are two distinct conditions, Sabat corrects dangerous misconceptions that plague our understanding of memory dysfunction and many other significant abilities that people with AD and dementia possess even in the moderate to severe stages. People diagnosed with AD retain awareness, thinking ability, and sense of self; crucially, Sabat demonstrates that there are ways to facilitate communication even when the person with AD has great difficulty finding the words he or she wants to use. From years spent exploring and observing the points of view and experiences of people diagnosed, Sabat strives to inform as well as to remind readers of the respect and empathy owed to those diagnosed and living with dementia. Alzheimer's Disease and Dementia conveys this type of information and more, which, when applied by family and professional caregivers, will help improve the quality of life of those diagnosed as well as of those who provide support and care.

Stolen Memories

Author : Marie Cloud
Publisher : iUniverse
ISBN 13 : 146971292X
Total Pages : 142 pages
Book Rating : 4.4/5 (697 download)

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Book Synopsis Stolen Memories by : Marie Cloud

Download or read book Stolen Memories written by Marie Cloud and published by iUniverse. This book was released on 2001-01-08 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: STOLEN MEMORIES deals with the impact of being a caregiver for a parent and how it not only affects one’s job and family, but also one’s mental and physical health. This story deals with the guilt that caregivers often carry as the gradually have to invade their parent’s privacy in order to keep them safe – everything from having to take a driver’s license away, to having to put a parent into an Alzheimer’s care facility. Marie encounters feelings of helplessness as she has to go against her mother’s wishes in order to care for her. Later her struggles through her own dark depression as the hopeless prognosis of Alzheimer’s disease takes its toll on her entire family, understands her agonizing sense that no matter what she did, it wasn’t enough. STOLEN MEMORIES deals with real issues that confront many of us. It is important that those who have been through caring for a parent with Alzheimer’s disease share their stories, as these experiences may help someone recognize and deal with this disease in its early stages.

Neurology in Clinical Practice

Author : Walter George Bradley
Publisher :
ISBN 13 : 9780750674690
Total Pages : 1672 pages
Book Rating : 4.6/5 (746 download)

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Book Synopsis Neurology in Clinical Practice by : Walter George Bradley

Download or read book Neurology in Clinical Practice written by Walter George Bradley and published by . This book was released on 2004 with total page 1672 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

The Poetics and Politics of Alzheimer’s Disease Life-Writing

Author : Martina Zimmermann
Publisher : Springer
ISBN 13 : 3319443887
Total Pages : 172 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Poetics and Politics of Alzheimer’s Disease Life-Writing by : Martina Zimmermann

Download or read book The Poetics and Politics of Alzheimer’s Disease Life-Writing written by Martina Zimmermann and published by Springer. This book was released on 2017-06-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This is the first book-length exploration of the thoughts and experiences expressed by dementia patients in published narratives over the last thirty years. It contrasts third-person caregiver and first-person patient accounts from different languages and a range of media, focusing on the poetical and political questions these narratives raise: what images do narrators appropriate; what narrative plot do they adapt; and how do they draw on established strategies of life-writing. It also analyses how these accounts engage with the culturally dominant Alzheimer’s narrative that centres on dependence and vulnerability, and addresses how they relate to discourses of gender and aging. Linking literary scholarship to the medico-scientific understanding of dementia as a neurodegenerative condition, this book argues that, first, patients’ articulations must be made central to dementia discourse; and second, committed alleviation of caregiver burden through social support systems and altered healthcare policies requires significantly altered views about aging, dementia, and Alzheimer’s patients.

While I Still Can...

Author : Rick Phelps
Publisher : Xlibris Corporation
ISBN 13 : 146918849X
Total Pages : 386 pages
Book Rating : 4.4/5 (691 download)

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Book Synopsis While I Still Can... by : Rick Phelps

Download or read book While I Still Can... written by Rick Phelps and published by Xlibris Corporation. This book was released on 2012-04-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rarely does one get an opportunity to experience the nightmare that is Alzheimers Disease from the perspective of the person who has been stricken with it. In his book, While I Still Can, Rick Phelps, the founder of Memory People, an online Alzheimers and dementia support group, changes all of that. Diagnosed with Early-Onset Alzheimers Disease in his 50's, Rick decided it was time the veil was lifted. Throughout this book the reader is given a firsthand account of: the early signs that Rick experienced, the loneliness he felt during the denial period of family and friends, the terror that gripped his heart upon receiving the undeniable diagnosis and, after the diagnosis, how he and his loved ones have learned to cope with this mind robbing and fatal disease. A real page turner, While I Still Can, affords an uncommon glimpse into the world of memory loss, while at the same time it tells the story of love, commitment, faith and courage in the face of a catastrophic disease.

Alzheimer's/Dementia from the Experiences of a Caregiver

Author : Rev. Frederick Trunk
Publisher : Xulon Press
ISBN 13 : 1619965844
Total Pages : 64 pages
Book Rating : 4.6/5 (199 download)

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Book Synopsis Alzheimer's/Dementia from the Experiences of a Caregiver by : Rev. Frederick Trunk

Download or read book Alzheimer's/Dementia from the Experiences of a Caregiver written by Rev. Frederick Trunk and published by Xulon Press. This book was released on 2012-02 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you are a caregiver, or know someone who is, you owe it to yourself to read this book. It is very important to know the phases of Alzheimer's as well as the effects it has, not only on the patient, but on those who care for, or live with the patient. If you know someone who is struggling with the challenge you need to know how to help them. This book will give you insight into the challenges of dementia and Alzheimer's from the prospective of a caregiver who started attending caregivers meetings shortly after he realized that his wife was having unusual challenges and behaviors. Frederick and Marjorie were caregivers for about three years for a couple from their church. They were not able to get satisfactory help from family members or friends so they stepped in and got the appropriate legal Power of Attorney and helped them get into assisted living. We took care of their needs until they passed away. During this period we learned a lot about care giving. Frederick has been caregiver for his wife Marjorie for eleven years. His wish is that the book he has written will get into the hands of those who are just beginning to recognize there is a problem as well as those who may be experiencing many years as a caregiver. He also wants people to know that getting help early on is very important and makes the challenge of care giving much easier. For over forty years Frederick has served as Minister of Music/Organist in eleven churches in New Jersey, Massachusetts and Georgia. He attended Northeastern Bible College and Seminary in Essex Fells, New Jersey, and International Christian College and Seminary in Plymouth, Florida where he earned a Bachelor of Music and a Masters in Ministry.

Alzheimer’s Disease

Author : Arun Jha
Publisher : Springer Nature
ISBN 13 : 3030567397
Total Pages : 107 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Alzheimer’s Disease by : Arun Jha

Download or read book Alzheimer’s Disease written by Arun Jha and published by Springer Nature. This book was released on 2020-09-29 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practically focused resource on the methodologies available for diagnosing and treating Alzheimer’s disease. The number of individuals affected by the disease continues to grow and as such there is an ever-increasing need for clear easy-to-digest guidance on how to appropriately diagnose and treat these patients. Within this work, chapters provide concise informative details of what this form of dementia is, how it can be diagnosed, managed and prevented making it ideal for those with limited experience in dealing with these patients. Information is provided on how to use a variety of the latest relevant techniques including mental state examinations, functional assessments, special investigations and the available drug treatments. Alzheimer’s Disease: Diagnosis & Treatment Guide is a concise clinical guide detailing how to diagnose and treat these patients. It’s easy-to-follow ideal for use by front-line physicians and trainees, who have no previous experience of diagnosing and treating this disease. The assessment component of the book is based on the WHO Mental Health Gap Action Plan (mhGAP) Dementia Intervention Guide for non-specialized settings.

Caregiving for Alzheimer’s Disease and Related Disorders

Author : Steven H. Zarit
Publisher : Springer
ISBN 13 : 9781489991515
Total Pages : 0 pages
Book Rating : 4.9/5 (915 download)

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Book Synopsis Caregiving for Alzheimer’s Disease and Related Disorders by : Steven H. Zarit

Download or read book Caregiving for Alzheimer’s Disease and Related Disorders written by Steven H. Zarit and published by Springer. This book was released on 2014-12-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assisting someone with Alzheimer’s disease or another illness that causes dementia is incredibly demanding and stressful for the family. Like many disabling conditions, Alzheimer’s disease leads to difficulty or inability to carry out common activities of daily life, and so family members take over a variety of tasks ranging from managing the person’s finances to helping with intimate activities such as bathing and dressing. Key coverage in Caregiving for Alzheimer’s Disease and Related Disorders includes: Early diagnosis and family dynamics Emotional needs of caregivers Developmentally appropriate long-term care for people with Alzheimer’s Family caregivers as members of the Alzheimer’s treatment Team Legal and ethical issues for caregivers Faith and spirituality The economics of caring for individuals with Alzheimer’s disease Cultural, racial, ethnic, and socioeconomic issues of minority caregivers Advances in Alzheimer’s disease research Caregiving for Alzheimer’s Disease and Related Disorders offers a wealth of insights and ideas for researchers, practitioners, and graduate students across the caregiving fields, including psychology, social work, public health, geriatrics and gerontology, and medicine as well as public and education policy makers.

The Caregiver

Author : Aaron Alterra
Publisher : Cornell University Press
ISBN 13 : 1501720589
Total Pages : 230 pages
Book Rating : 4.5/5 (17 download)

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Book Synopsis The Caregiver by : Aaron Alterra

Download or read book The Caregiver written by Aaron Alterra and published by Cornell University Press. This book was released on 2018-10-18 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aaron and Stella Alterra had been married for more than sixty years when Aaron began to notice puzzling lapses in his wife's memory. Innocuous at first, they became more severe and more alarming. After a series of appointments and tests, the Alterras were informed that Stella was one of the more than 4.5 million Americans with Alzheimer's disease. Combining medical research on the disease and often-painful anecdotes of memory loss, deteriorating motor functions, personality shifts, support-group and daycare experiences, and drug trials, Alterra chronicles his transformation from husband to caregiver after his wife's diagnosis. More than a chronology of one family's experience of Alzheimer's disease, The Caregiver is an intelligent, beautifully reflective testimony to how family members turned caregivers become the ultimate advocates for their loved ones in the face of a disease with no cure.