Ending Aging

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Publisher : Macmillan + ORM
ISBN 13 : 1429931833
Total Pages : 452 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Ending Aging by : Aubrey de Grey

Download or read book Ending Aging written by Aubrey de Grey and published by Macmillan + ORM. This book was released on 2007-09-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

A Means to an End

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Author :
Publisher : Oxford University Press
ISBN 13 : 0195348397
Total Pages : 252 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis A Means to an End by : William R. Clark

Download or read book A Means to an End written by William R. Clark and published by Oxford University Press. This book was released on 2002-02-28 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do we age? Is aging inevitable? Will advances in medical knowledge allow us to extend the human lifespan beyond its present limits? Because growing old has long been the one irreducible reality of human existence, these intriguing questions arise more often in the context of science fiction than science fact. But recent discoveries in the fields of cell biology and molecular genetics are seriously challenging the assumption that human lifespans are beyond our control. With such discoveries in mind, noted cell biologist William R. Clark clearly and skillfully describes how senescence begins at the level of individual cells and how cellular replication may be bound up with aging of the entire organism. He explores the evolutionary origin and function of aging, the cellular connections between aging and cancer, the parallels between cellular senescence and Alzheimer's disease, and the insights gained through studying human genetic disorders--such as Werner's syndrome--that mimic the symptoms of aging. Clark also explains how reduction in caloric intake may actually help increase lifespan, and how the destructive effects of oxidative elements in the body may be limited by the consumption of antioxidants found in fruits and vegetables. In a final chapter, Clark considers the social and economic aspects of living longer, the implications of gene therapy on senescence, and what we might learn about aging from experiments in cloning. This is a highly readable, provocative account of some of the most far-reaching and controversial questions we are likely to ask in the next century.

Reversing Human Aging

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Author :
Publisher : Quill
ISBN 13 : 9780688153847
Total Pages : 326 pages
Book Rating : 4.1/5 (538 download)

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Book Synopsis Reversing Human Aging by : Michael Fossel

Download or read book Reversing Human Aging written by Michael Fossel and published by Quill. This book was released on 1997-06-30 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: A groundbreaking book about the medical advances that will definitively prevent aging. In a startling glimpse of our possible future, we see how we may live for two to three hundred years longer, how age-related diseases will be eradicated, and how the aging press will be prevented if not reversed. Illus.

Human Aging

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Publisher : Academic Press
ISBN 13 : 0128227370
Total Pages : 384 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Human Aging by : Calogero Caruso

Download or read book Human Aging written by Calogero Caruso and published by Academic Press. This book was released on 2021-05-11 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. - Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging - Offers the ability to access cross-sectional knowledge more easily - Written by expert researchers in biogerontology who are actively involved in various fields within aging research

Ageless

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Publisher : Anchor
ISBN 13 : 0385544936
Total Pages : 353 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis Ageless by : Andrew Steele

Download or read book Ageless written by Andrew Steele and published by Anchor. This book was released on 2021-03-23 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

The End of Age

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Publisher : Profile Books Limited
ISBN 13 : 9781861972774
Total Pages : 129 pages
Book Rating : 4.9/5 (727 download)

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Book Synopsis The End of Age by : Tom Kirkwood

Download or read book The End of Age written by Tom Kirkwood and published by Profile Books Limited. This book was released on 2001 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aging, Death, and Human Longevity

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Author :
Publisher : Univ of California Press
ISBN 13 : 9780520938809
Total Pages : 292 pages
Book Rating : 4.9/5 (388 download)

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Book Synopsis Aging, Death, and Human Longevity by : Christine Overall

Download or read book Aging, Death, and Human Longevity written by Christine Overall and published by Univ of California Press. This book was released on 2003-02-04 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the help of medicine and technology we are living longer than ever before. As human life spans have increased, the moral and political issues surrounding longevity have become more complex. Should we desire to live as long as possible? What are the social ramifications of longer lives? How does a longer life span change the way we think about the value of our lives and about death and dying? Christine Overall offers a clear and intelligent discussion of the philosophical and cultural issues surrounding this difficult and often emotionally charged issue. Her book is unique in its comprehensive presentation and evaluation of the arguments—both ancient and contemporary—for and against prolonging life. It also proposes a progressive social policy for responding to dramatic increases in life expectancy. Writing from a feminist perspective, Overall highlights the ways that our biases about race, class, and gender have affected our views of elderly people and longevity, and her policy recommendations represent an effort to overcome these biases. She also covers the arguments surrounding the question of the "duty to die" and includes a provocative discussion of immortality. After judiciously weighing the benefits and the risks of prolonging human life, Overall persuasively concludes that the length of life does matter and that its duration can make a difference to the quality and value of our lives. Her book will be an essential guide as we consider our social responsibilities, the meaning of human life, and the prospects of living longer.

The End of Memory

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Author :
Publisher : Macmillan
ISBN 13 : 1466887915
Total Pages : 296 pages
Book Rating : 4.4/5 (668 download)

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Book Synopsis The End of Memory by : Jay Ingram

Download or read book The End of Memory written by Jay Ingram and published by Macmillan. This book was released on 2015-09-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illuminating biography of "the plague of the twenty-first century" and scientists' efforts to understand and, they hope, prevent it, The End of Memory is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions. It is a wicked disease that robs its victims of their memories, their ability to think clearly, and ultimately their lives. For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects while family members sit by, watching their loved ones disappear a little more each day until the person they used to know is gone forever. The disease was first described by German psychologist and neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer's, but it still affects millions around the world, and there is no cure in sight. In The End of Memory, award-winning science author Jay Ingram writes a biography of this disease that attacks the brains of patients. He charts the history of the disease from before it was noted by Alois Alzheimer through to the twenty-first century, explains the fascinating science of plaques and tangles, recounts the efforts to understand and combat the disease, and introduces us to the passionate researchers who are working to find a cure.

The Telomere Effect

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Author :
Publisher : Grand Central Publishing
ISBN 13 : 1455587966
Total Pages : 307 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis The Telomere Effect by : Dr. Elizabeth Blackburn

Download or read book The Telomere Effect written by Dr. Elizabeth Blackburn and published by Grand Central Publishing. This book was released on 2017-01-03 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

Retooling for an Aging America

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Author :
Publisher : National Academies Press
ISBN 13 : 0309131952
Total Pages : 316 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Retooling for an Aging America by : Institute of Medicine

Download or read book Retooling for an Aging America written by Institute of Medicine and published by National Academies Press. This book was released on 2008-08-27 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first of the nation's 78 million baby boomers begin reaching age 65 in 2011, they will face a health care workforce that is too small and woefully unprepared to meet their specific health needs. Retooling for an Aging America calls for bold initiatives starting immediately to train all health care providers in the basics of geriatric care and to prepare family members and other informal caregivers, who currently receive little or no training in how to tend to their aging loved ones. The book also recommends that Medicare, Medicaid, and other health plans pay higher rates to boost recruitment and retention of geriatric specialists and care aides. Educators and health professional groups can use Retooling for an Aging America to institute or increase formal education and training in geriatrics. Consumer groups can use the book to advocate for improving the care for older adults. Health care professional and occupational groups can use it to improve the quality of health care jobs.

Epigenetics of Aging

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Ending Ageism, or How Not to Shoot Old People

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Author :
Publisher : Rutgers University Press
ISBN 13 : 0813589304
Total Pages : 366 pages
Book Rating : 4.8/5 (135 download)

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Book Synopsis Ending Ageism, or How Not to Shoot Old People by : Margaret Morganroth Gullette

Download or read book Ending Ageism, or How Not to Shoot Old People written by Margaret Morganroth Gullette and published by Rutgers University Press. This book was released on 2017-08-23 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the MLA Prize for Independent Scholars and the APA's Florence L. Denmark Award for Contributions to Women and Aging When the term “ageism” was coined in 1969, many problems of exclusion seemed resolved by government programs like Social Security and Medicare. As people live longer lives, today’s great demotions of older people cut deeper into their self-worth and human relations, beyond the reach of law or public policy. In Ending Ageism, or How Not to Shoot Old People, award-winning writer and cultural critic Margaret Morganroth Gullette confronts the offenders: the ways people aging past midlife are portrayed in the media, by adult offspring; the esthetics and politics of representation in photography, film, and theater; and the incitement to commit suicide for those with early signs of “dementia.” In this original and important book, Gullette presents evidence of pervasive age-related assaults in contemporary societies and their chronic affects. The sudden onset of age-related shaming can occur anywhere—the shove in the street, the cold shoulder at the party, the deaf ear at the meeting, the shut-out by the personnel office or the obtuseness of a government. Turning intimate suffering into public grievances, Ending Ageism, Or How Not to Shoot Old People effectively and beautifully argues that overcoming ageism is the next imperative social movement of our time. About the cover image: This elegant, dignified figure--Leda Machado, a Cuban old enough to have seen the Revolution--once the center of a vast photo mural, is now a fragment on a ruined wall. Ageism tears down the structures that all humans need to age well; to end it, a symbol of resilience offers us all brisk blue-sky energy. “Leda Antonia Machado” from “Wrinkles of the City, 2012.” Piotr Trybalski / Trybalski.com. Courtesy of the artist. A Declaration of Grievances "A Declaration of Grievances" was written by Margaret Morganroth Gullette and is excerpted from her book Ending Ageism, or How Not to Shoot Old People (2017, Rutgers University Press). The poster was designed by Carolyn Kerchof.​ A Declaration of Grievances (in English): https://d3tto5i5w9ogdd.cloudfront.net/wp-content/uploads/2023/01/15175130/A-Declaration-of-Grievances_Eng.pdf​ A Declaration of Grievances (in Spanish): https://d3tto5i5w9ogdd.cloudfront.net/wp-content/uploads/2023/01/15175131/A-Declaration-of-Grievances_Spanish.pdf ​A Declaration of Grievances (in French): https://d3tto5i5w9ogdd.cloudfront.net/wp-content/uploads/2023/01/15175130/A-Declaration-of-Grievances_French.pdf ​A Declaration of Grievances (in German): https://d3tto5i5w9ogdd.cloudfront.net/wp-content/uploads/2023/01/15175131/A-Declaration-of-Grievances_German.pdf Print the PDF (make sure to click "fit to page") and hang the Declaration up in your home or place of work. Please share this link with other people you know who care about the rights of older persons. Share on social media with the hashtags #ADeclarationOfGrievances and #EndingAgeismGullette. For more information, an excerpt, links to reviews, and special offers on this book, go to: https://www.rutgersuniversitypress.org/ending-ageism Related website: (https://www.brandeis.edu/wsrc/scholars/profiles/gullette.html)

Better with Age

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190279990
Total Pages : 257 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Better with Age by : Dr. Alan D. Castel

Download or read book Better with Age written by Dr. Alan D. Castel and published by Oxford University Press. This book was released on 2018-08-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Age is an important number, but it can also be deceiving. After 40, most people say they feel younger than their years, some lie about their age, and many attempt to hide the signs of growing old. Better with Age addresses the many myths and paradoxes about the aging process. Although most people think of their later years in terms of decline, they can be one of the best times in life. This book presents the latest scientific research about the psychology of aging, coupled with insights from those who have succeeded in doing it well, such as Maya Angelou, Bob Newhart, Jared Diamond, John Glenn, and John Wooden. We are all aging, and many people are concerned about what to expect with advancing years. Retirement, happiness, and brain health are some of the many topics covered in this book. Better with Age shows what we can do now, at any stage in life, to make sure we enjoy old age.

The Biology of Senescence

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Author :
Publisher : CreateSpace
ISBN 13 : 9781456392420
Total Pages : 274 pages
Book Rating : 4.3/5 (924 download)

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Book Synopsis The Biology of Senescence by : Alex Comfort

Download or read book The Biology of Senescence written by Alex Comfort and published by CreateSpace. This book was released on 2010-11-25 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Senescence

Lifespan

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Publisher : Atria Books
ISBN 13 : 1501191977
Total Pages : 432 pages
Book Rating : 4.5/5 (11 download)

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Book Synopsis Lifespan by : David A. Sinclair

Download or read book Lifespan written by David A. Sinclair and published by Atria Books. This book was released on 2019-09-10 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Ageism Unmasked

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Author :
Publisher : Steerforth
ISBN 13 : 1586423223
Total Pages : 193 pages
Book Rating : 4.5/5 (864 download)

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Book Synopsis Ageism Unmasked by : Tracey Gendron

Download or read book Ageism Unmasked written by Tracey Gendron and published by Steerforth. This book was released on 2022-03-01 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do we still tolerate stereotypes and discrimination based on age? This bold account of the history and present-day realities of ageism by a nationally recognized gerontologist and speaker uncovers ageism's roots, impact, and how each of us can create a new reality of elderhood. Ageism Unmasked shifts the lens, enabling us to see that we tolerate, and sometimes actively promote, attitudes and behaviors toward differently aged people that we would reject and condemn if applied to any other group. It peels back the layers to expose how cultural norms and unconscious prejudices have seeped into our lives, silently shaping our treatment of others based on their age and our own misconceptions about aging—and about ourselves. Offering an all-inclusive approach, Dr. Tracey Gendron reveals the biases behind our false understanding of aging, sharing powerful opportunities for personal growth along with strategies to help create an anti-ageist society. Ageism Unmasked will help readers let go of our desperate need to stay young… exposing how we personally, systematically, structurally, and institutionally stigmatize being old. Ageism Unmasked will help readers appreciate both the challenges and opportunities of how we all age… showing how ageism is prejudice towards both younger and older people. Ageism Unmasked will help readers reset our expectations for getting old… providing the tools to anticipate and experience elderhood as a time of renewed meaning and purpose, empowering each of us to create our own definition of successful aging. Ageism Unmasked continues Dr. Gendron's transformative work inspiring people of all ages to embrace aging as our universal and lifelong process of developing over time — biologically, psychologically, socially, and spiritually.

Aging with Grace

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Author :
Publisher : Bantam
ISBN 13 : 0307481239
Total Pages : 258 pages
Book Rating : 4.3/5 (74 download)

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Book Synopsis Aging with Grace by : David Snowdon

Download or read book Aging with Grace written by David Snowdon and published by Bantam. This book was released on 2008-11-19 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1986 Dr. David Snowdon, one of the world’s leading experts on Alzheimer’s disease, embarked on a revolutionary scientific study that would forever change the way we view aging—and ultimately living. Dubbed the “Nun Study” because it involves a unique population of 678 Catholic sisters, this remarkable long-term research project has made headlines worldwide with its provocative discoveries. Yet Aging with Grace is more than a groundbreaking health and science book. It is the inspiring human story of these remarkable women—ranging in age from 74 to 106—whose dedication to serving others may help all of us live longer and healthier lives. Totally accessible, with fascinating portraits of the nuns and the scientists who study them, Aging with Grace also offers a wealth of practical findings: • Why building linguistic ability in childhood may protect against Alzheimer’s • Which ordinary foods promote longevity and healthy brain function • Why preventing strokes and depression is key to avoiding Alzheimer’s • What role heredity plays, and why it’s never too late to start an exercise program • How attitude, faith, and community can add years to our lives A prescription for hope, Aging with Grace shows that old age doesn’t have to mean an inevitable slide into illness and disability; rather it can be a time of promise and productivity, intellectual and spiritual vigor—a time of true grace.