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Download The Effects Of Ultraviolet Light On Rna And Protein Synthesis In Human Diploid Fibroblasts Maintained In A Nonproliferative State full books in PDF, epub, and Kindle. Read online The Effects Of Ultraviolet Light On Rna And Protein Synthesis In Human Diploid Fibroblasts Maintained In A Nonproliferative State ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :
Publisher :
ISBN 13 :
Total Pages : 1160 pages
Book Rating : 4.:/5 (31 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Reinert
Publisher : Springer Science & Business Media
ISBN 13 : 354037390X
Total Pages : 336 pages
Book Rating : 4.5/5 (43 download)
Download or read book Cell Cycle and Cell Differentiation written by J. Reinert and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by botanists and zoologists, as well as by cell and molecular biologists. These problems are crisp and well-defined. The current state of "cell differentiation" stands in sharp contrast. This, one of the oldest problems in experimental biology, almost defies definition today. The difficulties arise not only from a lack of pertinent information on the regulatory mechanisms, but also from conflicting basic concepts in this field. One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.
Author : Hisao Masai
Publisher : Springer
ISBN 13 : 9811069557
Total Pages : 581 pages
Book Rating : 4.8/5 (11 download)
Download or read book DNA Replication written by Hisao Masai and published by Springer. This book was released on 2018-01-22 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells’ strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts are being generated to explain how genome DNA replication is achieved with such high adaptability and plasticity. With the development of new methods including cryoelectron microscopy analyses of huge protein complexes, single molecular analyses of initiation and elongation of DNA replication, and total reconstitution of eukaryotic DNA replication with purified factors, the field is enjoying one of its most exciting moments, and this highly timely book conveys that excitement to all interested readers.
Author : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher : National Academies Press
ISBN 13 : 0309133343
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)
Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Author : S. Guidet
Publisher : Springer Science & Business Media
ISBN 13 : 1461518091
Total Pages : 365 pages
Book Rating : 4.4/5 (615 download)
Download or read book Progress in Cell Cycle Research written by S. Guidet and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Cell Cycle Research is a new annual series designed to be the source for up-to-date research on this rapidly expanding field. Review articles by international experts examine various aspects of cell division regulation from fundamental perspectives to potential medical applications. Researchers as well as advanced undergraduate and graduate students in cell biology, biochemistry, and molecular biology will benefit from this series.
Author : Daniel R. Marshak
Publisher : CSHL Press
ISBN 13 : 9780879696733
Total Pages : 566 pages
Book Rating : 4.6/5 (967 download)
Download or read book Stem Cell Biology written by Daniel R. Marshak and published by CSHL Press. This book was released on 2001 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are the focus of intense interest from a growing, multidisciplinary community of investigators with new tools for isolating and characterizing these elusive cell types. This volume, which features contributions from many of the world's leading laboratories, provides a uniquely broad and authoritative basis for understanding the biology of stem cells and the current excitement about their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their collaborators in the emerging field of regenerative medicine.
Author : Sunil C. Kaul
Publisher : Springer
ISBN 13 : 3319591924
Total Pages : 517 pages
Book Rating : 4.3/5 (195 download)
Download or read book Science of Ashwagandha: Preventive and Therapeutic Potentials written by Sunil C. Kaul and published by Springer. This book was released on 2017-09-13 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.
Author : Errol C. Friedberg
Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.3/5 (97 download)
Download or read book DNA Repair written by Errol C. Friedberg and published by . This book was released on 1981 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eytan R. Barnea
Publisher : Springer Science & Business Media
ISBN 13 : 1447107071
Total Pages : 316 pages
Book Rating : 4.4/5 (471 download)
Download or read book Cancer and Pregnancy written by Eytan R. Barnea and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.
Author : David P. Bazett-Jones
Publisher : Springer
ISBN 13 : 3319388827
Total Pages : 501 pages
Book Rating : 4.3/5 (193 download)
Download or read book The Functional Nucleus written by David P. Bazett-Jones and published by Springer. This book was released on 2016-10-17 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Author : Stephen Bondy
Publisher : Springer Science & Business Media
ISBN 13 : 1607616025
Total Pages : 468 pages
Book Rating : 4.6/5 (76 download)
Download or read book Aging and Age-Related Disorders written by Stephen Bondy and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.
Author : Monica Florin-Christensen
Publisher : Springer
ISBN 13 : 3319701320
Total Pages : 439 pages
Book Rating : 4.3/5 (197 download)
Download or read book Parasitic Protozoa of Farm Animals and Pets written by Monica Florin-Christensen and published by Springer. This book was released on 2018-04-17 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth yet concise overview of the most common and emerging protozoa that cause diseases in both farm animals and companion animals. As outlined in the concise introduction, pathogenic protozoans represent an evolutionary highly diverse and little understood group of disease-causing microorganisms. For each of the featured parasitic unicellular eukaryotes, it discusses the morphology, lifecycle, epidemiology and host-pathogen interactions. In addition, the book highlights the latest developments in diagnostic methods, as well as prevention and treatment strategies. Thorough information on genomes and genetic manipulation strategies for some of the protozoa covered in this book is also included. Infections involving parasitic protozoa can cause productivity losses and/or reduce the quality of life of infected animals. Some infections are zoonotic, posing an on-going public health threat. In most cases, prevention and treatment are either non-existent or need considerable improvement. On the other hand, a great deal of research has recently been conducted on these organisms, yielding valuable new information on their global distribution and revealing the mechanisms of host-pathogen interactions at the molecular level – and essential insights that can be used for the development of new control tools. This book includes extensive information on both basic aspects and recent scientific discoveries on these protozoa and thus constitutes a unique resource for students, veterinarians, and researchers alike.
Author : Andrew T Raftery
Publisher : Elsevier Health Sciences
ISBN 13 : 070205058X
Total Pages : 660 pages
Book Rating : 4.7/5 (2 download)
Download or read book Applied Basic Science for Basic Surgical Training E-Book written by Andrew T Raftery and published by Elsevier Health Sciences. This book was released on 2011-12-22 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. It has been written to encompass the basic anatomy, physiology and pathology required by the syllabus of the UK Royal Colleges and the Intercollegiate Surgical Curriculum Project. For this Second Edition many of the chapters have been updated, especially the chapters on immunology, basic microbiology, the endocrine and locomotor systems and the breast. An attempt has been made throughout to indicate the clinical relevance of the facts and the reason for learning them. There are several new contributors to the author team, all of whom are experts in their field and many of them are, or have been, experienced examiners at the various UK Royal Colleges. Brings together three basic sciences in one book and presents them in an integrated format. Presents the sciences at the right level for surgical trainees. Written in a straightforward and readable style. Thoroughly revised to take account of latest changes in basic surgical training, especially the chapters on immunology, basic microbiology, the endocrine and locomotor systems and the breast
Author : Philip L. Chambers
Publisher : Springer
ISBN 13 : 9783540185123
Total Pages : 0 pages
Book Rating : 4.1/5 (851 download)
Download or read book The Target Organ and the Toxic Process written by Philip L. Chambers and published by Springer. This book was released on 1988-09-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anoop N
Publisher : JP Medical Ltd
ISBN 13 : 9350904756
Total Pages : 294 pages
Book Rating : 4.3/5 (59 download)
Download or read book Synopsis of Pathology written by Anoop N and published by JP Medical Ltd. This book was released on 2013-07-30 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synopsis of Pathology provides a concise overview of pathology for medical trainees. Divided into two sections, general pathology and systemic pathology, the first chapters discuss topics such as cell injury and death, tissue repair and regeneration, immune system diseases, genetic and paediatric diseases and nutritional diseases. The section on systemic pathology describes pathology of specific regions of the anatomy, including heart, liver, pancreas, endocrine system, skin and nervous system. Presented in a quick reference, easy to follow format, this resource includes numerous tables, text boxes, flow charts and illustrations to highlight key points and enhance learning. 50 clinical essay questions are included, as well as clinical pathology notes on diagnosis, key topics and laboratory values, and an extensive bibliography. Key points Concise overview of pathology for medical trainees Covers general and systemic pathology, with in depth discussion on different anatomical organs Quick reference format with numerous tables, text boxes, flow charts and illustrations Includes 50 clinical essay questions, notes on diagnosis, key topics and laboratory values
Author : Valerie W. Hu
Publisher : Springer
ISBN 13 : 9781461360278
Total Pages : 430 pages
Book Rating : 4.3/5 (62 download)
Download or read book The Cell Cycle written by Valerie W. Hu and published by Springer. This book was released on 2012-11-02 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the cell cycle has grown explosively in recent years as a result of the identification of key cell cycle regulators and their substrates. Aside from enhancing our understanding of normal cellular growth controls, this new knowledge has also becn valuable in elucidating mechanisms of growth deregulation which occur in diseased states, such as cancer and, in some instances, viral or parasitic infections. The Thirteenth Washington International Spring Symposium was organized with the intention of bringing together scientists working on different aspects of the cell cycle. Scientific topics presented ranged from molecular regulators and effectors to mitosis specific changes in cell architecture to the role of the cell cycle in development and disease. The goal of this gathering was to help formulate a more comprehensive and integrated picture of events driving and being driven by the cell cycle, as well as to evaluate the possibilities for clinical application of this knowledge. This symposium, held in Washington, D.C. from May 10-14, 1993, was attended by more than 400 scientists from 20 countries, including many of the scientific leaders in this field. This volume contains most of the papers presented at the seven plenary sessions in addition to selected contributions from a total of nine special oral and poster sessions.
Author : Mansi Arora
Publisher : Springer
ISBN 13 : 9789811315671
Total Pages : 0 pages
Book Rating : 4.3/5 (156 download)
Download or read book Cancer RNome: Nature & Evolution written by Mansi Arora and published by Springer. This book was released on 2018-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, researchers working in the field of cancer biology have shifted their focus from genetic defects to epigenetic dysregulation, especially that of non-coding RNAs (ncRNAs). This book encompasses a comprehensive review of the transcriptional landscape of the cell and its involvement in the cancer pathophysiology. The first two chapters elucidate the basics of biosynthesis, mechanism of action and modulation of the epigenetic regulation of gene expression by coding as well as non-coding RNAs. The third chapter discusses the aberrant expression of the cellular RNome in the cancer cells and highlights its role in the orchestration of processes involved in evolution as well as the sustenance of cancer cells. The fourth chapter describes the recent advances in the field of translating the transcriptome into diagnostic/prognostic biomarkers and as targets for novel anti-cancer therapies. The final chapter then reviews the emerging experimental approaches to screen, identify and explore the functions of ncRNAs. Providing valuable insights into the field of RNome in the context of cancer, this book is helpful to students, researchers and clinicians..
