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The Effects Of Oxidative Damage On In Vivo Aging Density And Survival Of Baboon Red Blood Cells
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Book Synopsis The Effects of Oxidative Damage on In Vivo Aging, Density, and Survival of Baboon Red Blood Cells by : J. McKenney
Download or read book The Effects of Oxidative Damage on In Vivo Aging, Density, and Survival of Baboon Red Blood Cells written by J. McKenney and published by . This book was released on 1992 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: To assess the relationships among density, age, and survival of baboon red blood cells, hydrogen peroxide-treated (oxidized) red blood cells and untreated (non-oxidized) red blood cells were labeled with 51-Cr and auto transfused. Hydrogen peroxide in a final concentration of 339 micro mol/liter was used to treat the baboon red blood cells. Blood samples were collected following autotransfusion of the non-oxidized and oxidized red blood cells. These samples were processed as unfractionated red blood cells and as fractionated top, intermediate, and bottom red blood cells consisting of 6 bands isolated using percoll-hypaque density gradients. Oxidized unfractionated red blood cells and oxidized red blood cells in the bottom fraction consisting of 6 bands exhibited significantly reduced 51-Cr 24-hour posttransfusion survival values. The T-1/2 values in the bottom fraction were significantly lower in the oxidized than in the non-oxidized red blood cells. As the more dense red blood cells were removed from the circulation, the movement of radioactivity from the less dense top red blood cell fraction to the more dense bottom fraction was reduced. In another aspect of this study, non-oxidized and oxidized unfractionated and fractionated red blood cells were labeled with biotin. Percoll hypaque density gradients were used to separate the bottom red blood cell fraction containing 3 bands or 6 bands. Twenty minutes after the autotransfusion of these biotin-labeled non-fractionated and fractionated red blood cells, blood samples were collected. The biotin-labeled red blood cells were recovered on avidin plates, labeled with 51-Cr, and autotransfused. Samples were collected for 24-hour posttransfusion survival and lifespan measurement. The 24-hour posttransfusion survival values of the oxidized non-fractionated red blood cells were only 77% compared to 89% for the non-oxidized non-fractionated red blood cells.
Book Synopsis Environmental Oxidants by : Jerome O. Nriagu
Download or read book Environmental Oxidants written by Jerome O. Nriagu and published by John Wiley & Sons. This book was released on 1994-06-16 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemical enigma that is both a pollutant and anantipollutant--and environmental science's newest causecelebre.oxidants Responsible for chemical reactions both harmfuland benign, oxidants represent the sort of chemical puzzle thathave scientists both concerned and fascinated. Implicated in deadlysmog episodes and arteriosclerosis, oxidants have also played amajor role in treating polluted waters and in certain anticancerdrugs. A broad-based, up-to-date examination of the environmentalchemistry and toxicology of oxidants, Environmental Oxidants is acompendium of the latest research being done in the field. Bringingtogether the work of noted researches, the book contains a detailedlook at: * Evolution, production, distribution, and fate of oxidants in theatmosphere, hydrosphere, and biosphere * Influence of human activities on oxidative processes in theatmosphere * Oxidative stress at the cellular, systemic, and ecosystemlevels * Use of oxidants in wastewater treatment processes A selective and incisive look at the current state of research onoxidants, Environmental Oxidants provides environmental scientistsand engineers with an informative, detailed discussion of just howand why oxidants have emerged as a key issue in human health andenvironmental integrity.
Book Synopsis Annual Meeting - American Society of Hematology by : American Society of Hematology
Download or read book Annual Meeting - American Society of Hematology written by American Society of Hematology and published by . This book was released on 1989 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Disorders of Hemoglobin by : Martin H. Steinberg
Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.
Download or read book Index Medicus written by and published by . This book was released on 2002-07 with total page 1896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis The Evolution of Senescence in the Tree of Life by : Richard P. Shefferson
Download or read book The Evolution of Senescence in the Tree of Life written by Richard P. Shefferson and published by Cambridge University Press. This book was released on 2017-02-23 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude of different animals (including humans), plants and microbes, giving the reader a complete overview of recent developments and of the controversies currently surrounding the topic. Written by specialists from a variety of disciplines, this book is a valuable source of information for students and researchers interested in ageing and life history traits and populations.
Book Synopsis Biomedical Index to PHS-supported Research by :
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1989 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Profile for N-nitrosodimethylamine by :
Download or read book Toxicological Profile for N-nitrosodimethylamine written by and published by . This book was released on 1989 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Profile for Pentachlorophenol by :
Download or read book Toxicological Profile for Pentachlorophenol written by and published by . This book was released on 2001 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Arsenic in Drinking Water by : National Research Council
Download or read book Arsenic in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2001-11-26 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having safe drinking water is important to all Americans. The Environmental Protection Agency's decision in the summer of 2001 to delay implementing a new, more stringent standard for the maximum allowable level for arsenic in drinking water generated a great deal of criticism and controversy. Ultimately at issue were newer data on arsenic beyond those that had been examined in a 1999 National Research Council report. EPA asked the National Research Council for an evaluation of the new data available. The committee's analyses and conclusions are presented in Arsenic in Drinking Water: 2001 Update. New epidemiological studies are critically evaluated, as are new experimental data that provide information on how and at what level arsenic in drinking water can lead to cancer. The report's findings are consistent with those of the 1999 report that found high risks of cancer at the previous federal standard of 50 parts per billion. In fact, the new report concludes that men and women who consume water containing 3 parts per billion of arsenic daily have about a 1 in 1,000 increased risk of developing bladder or lung cancer during their lifetime.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1987 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diet and Health by : National Research Council
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Book Synopsis Antioxidants in Therapy and Preventive Medicine by : Ingrid Emerit
Download or read book Antioxidants in Therapy and Preventive Medicine written by Ingrid Emerit and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported. With this discovery was born a new scientific field, in which oxygen, necessary for aerobi c 1 ife on thi s planet, had to be cons i dered also in terms of its toxicity and stresses. This stimulated the search for knowledge of active oxygen species in biology and medicine. Superoxide and other reactive oxygen species are now implicated in many disease processes. Major advances have been achieved during these past years with respect to free radical generation and mechanisms of free radical action in causing tissue injury. In parallel, the possibil ity of influencing free radical related disease processes by antioxidant treatment was studied in various in vitro and in vivo systems. This was the unique theme of a conference organized in Paris by the Society for Free Radical Research (December 9-10, 1988) which brought together experts from basic sciences and clinicians in order to evaluate the current status of antioxidant therapy. The conference emphasized fundamental processes in antioxidant action. Among the major topics were superoxide dismutase (SOD) and low molecular weight substances with such activity, called SOD mimics. Other antioxidant enzymes were also considered. Antioxidant vitamins, in particular vitamins E and C, other naturally occurri ng antioxidants and vari ous synthet i c antioxidants were included in the presentations as there is now a rapidly developing series of compounds with potentially interesting clinical applications.
Book Synopsis Toxicological Profile for Chlordane by :
Download or read book Toxicological Profile for Chlordane written by and published by . This book was released on 1994 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Profile for Nitrophenols by :
Download or read book Toxicological Profile for Nitrophenols written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Profile for Cobalt by :
Download or read book Toxicological Profile for Cobalt written by and published by . This book was released on 1992 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Profile for Acetone by :
Download or read book Toxicological Profile for Acetone written by and published by . This book was released on 1994 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
