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The Clinical Effectiveness And Cost Effectiveness Of Interferon Beta And Glatiramer Acetate In The Management Of Relapsing Remitting And Secondary Progressive Multiple Sclerosis
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Book Synopsis The Clinical Effectiveness and Cost-effectiveness of Interferon-beta and Glatiramer Acetate in the Management of Relapsing/remitting and Secondary-progressive Multiple Sclerosis by :
Download or read book The Clinical Effectiveness and Cost-effectiveness of Interferon-beta and Glatiramer Acetate in the Management of Relapsing/remitting and Secondary-progressive Multiple Sclerosis written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This report describes one of two studies undertaken to address a Congressional mandate to evaluate the cost-effectiveness of expanded drug coverage to Medicare under the Medicare Replacement Drug Demonstration. The demonstration aimed to improve beneficiary access to selected new oral anti-cancer drugs and other self-injected medications such as those used to treat multiple sclerosis (MS). Currently, treatment of MS using IFN beta-1a is covered under Medicare Part B when administered intra-muscularly by a physician. Until the new prescription drug benefit (Medicare Part D) began in 2006, subcutaneous injection of IFN beta-1a administered by the patient was not covered. The MRDD provided temporary national coverage to all self-administered treatments during the 16 months before Medicare Part D was implemented. Patient cost-sharing under the MRDD was structured to resemble Part D.
Book Synopsis Valuing Health Care by : Frank A. Sloan
Download or read book Valuing Health Care written by Frank A. Sloan and published by Cambridge University Press. This book was released on 1996-08-28 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: As expenditure on health care has increasingly become an area of public debate and concern, public and private health care decision-makers have called for more rigorous use of cost-benefit and cost-effectiveness analysis to guide spending. Concerns have arisen, however, about the overall quality of such analyses. This book discusses and evaluates best-practice methods of conducting cost-benefit and cost-effectiveness studies of pharmaceuticals and other medical technologies. It encompasses a wide variety of topics, ranging from measuring cost and effectiveness to discounting to the use of dynamic modelling of cost-effectiveness. The book also includes conceptual and practical aspects of cost-effectiveness analysis by researchers who have conducted applied research in these areas. Rarely does the book provide a singular solution to a measurement problem; rather, the reader is directed to choices among alternative approaches and an analysis of the advantages and disadvantages of each.
Book Synopsis Neuroimmunological Diseases by : Susumu Kusunoki
Download or read book Neuroimmunological Diseases written by Susumu Kusunoki and published by Springer. This book was released on 2018-05-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies. Written by renowned experts who have made major contributions in the field, such as identifying neuromyelitis optica as an immunopathological clinical condition, identifying the role of ganglioside and ganglioside-complex antibodies in Guillain-Barré syndrome, and developing a novel treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome, the book summarizes recent advances in basic and clinical research. Neuroimmunological Diseases is a useful resource for not only researchers but also neurologists who are engaged in the management of neuroimmunological diseases.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Multiple Sclerosis by : Institute of Medicine
Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Book Synopsis Goldman-Cecil Medicine E-Book by : Lee Goldman
Download or read book Goldman-Cecil Medicine E-Book written by Lee Goldman and published by Elsevier Health Sciences. This book was released on 2019-08-16 with total page 2972 pages. Available in PDF, EPUB and Kindle. Book excerpt: To be the best doctor you can be, you need the best information. For more than 90 years, what is now called Goldman-Cecil Medicine has been the authoritative source for internal medicine and the care of adult patients. Every chapter is written by acclaimed experts who, with the oversight of our editors, provide definitive, unbiased advice on the diagnosis and treatment of thousands of common and uncommon conditions, always guided by an understanding of the epidemiology and pathobiology, as well as the latest medical literature. But Goldman-Cecil Medicine is not just a textbook. Throughout the lifetime of each edition, periodic updates continually include the newest information from a wide range of journals. Furthermore, Goldman-Cecil Medicine is available for all users of ClinicalKey, Elsevier’s full library of subspecialty textbooks that can be accessed by readers who may want even more in-depth information. More than 400 chapters authored by a veritable "Who’s Who" of modern medicine A practical, templated organization with an emphasis on evidence-based references Thousands of algorithms, figures, and tables that make its information readily accessible Supplemented by over 1500 board-style questions and answers to help you prepare for certification and recertification examinations
Download or read book Multiple Sclerosis written by and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book BMJ written by and published by . This book was released on 2003 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis McAlpine's Multiple Sclerosis by : Alastair Compston
Download or read book McAlpine's Multiple Sclerosis written by Alastair Compston and published by . This book was released on 1998 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.
Book Synopsis Health Economics by : Ceri J. Phillips
Download or read book Health Economics written by Ceri J. Phillips and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides all the necessary information in a readablestyle that can be understood by anyone with even the most basicknowledge of mathematics Health Economics is ideal for allhealth professionals who are required to make policy decisions– including hospital managers, clinical directors andpartners in family practices. It is suited to health policy makersat national level as well as those in local trusts. The clear andconcise way in which the book is written also makes it a perfectintroductory text for students of health economics. Health Economics provides you with the tools to: Read and critique economic evaluations Understand the economic forces at work in specificenvironments Make optimum choices in terms of benefits and outcomes
Book Synopsis Primary Progressive Multiple Sclerosis by : M. Filippi
Download or read book Primary Progressive Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. " Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin ical trials have excluded PPMS patients on two counts. Clinical worsening devel ops slowly in PPMS and may not be recognized during the course of a 2-or 3-year trial even in untreated control patients. This factor alone adds to the potential for a type 2 error or, at the very least, inflates the sample size and duration of the trial. In addition, there is mounting evidence that progressive axonal degeneration and neuronal loss (rather than active, recurrent inflammation) may be important components of the pathology in this form of the disease. Although contemporary trials are evaluating whether PPMS patients may benefit from treatment with the ~-interferons and glatiramer acetate, preliminary, uncontrolled clinical experi ence suggests that the results may not be dramatic.
Book Synopsis Glatiramer Acetate and Interferon Beta 1a and 1b for Clinically Isolated Syndrome by : Dinsie Williams
Download or read book Glatiramer Acetate and Interferon Beta 1a and 1b for Clinically Isolated Syndrome written by Dinsie Williams and published by . This book was released on 2019 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: This review aims to summarize and evaluate evidence regarding the clinical effectiveness and safety of glatiramer acetate, IFN beta-1a, and IFN beta-1b, in treating patients with clinically isolated syndrome (CIS). The review also aims to summarize and assess relevant evidence-based guidelines.
Author :Centers for Disease Control and Prevention CDC Publisher :Oxford University Press ISBN 13 :0190628634 Total Pages :705 pages Book Rating :4.1/5 (96 download)
Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC
Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Book Synopsis Multiple Sclerosis Therapeutics by : Richard Rudick
Download or read book Multiple Sclerosis Therapeutics written by Richard Rudick and published by CRC Press. This book was released on 1999-09-01 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.
Book Synopsis Kumar and Clark's Clinical Medicine E-Book by : Adam Feather
Download or read book Kumar and Clark's Clinical Medicine E-Book written by Adam Feather and published by Elsevier Health Sciences. This book was released on 2020-06-19 with total page 1585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its tenth edition, Kumar & Clark’s Clinical Medicine is fully updated and revised under a new team of editors.Featuring new chapters covering: o Diagnosis: the art of being a doctor – helping readers to develop a confident clinical method in interactions with patientso Elderly medicine, frailty and multimorbidityo Public healtho Surgeryo Evidence-based medicineo Sepsis and the treatment of bacterial infection o Haematological Oncologyo Venous thromboembolic diseaseo Hypertensiono Men’s healthEnhanced clinical skills content has been added to most chapters - helping readers tailor history-taking and examination skills to specific specialty-based contexts.Bonus online content - including self-assessment, common clinical and international cases, cardiovascular and respiratory audio material, clinical examination videos and bite-sized topic pages covering major conditions.Heavily revised throughout with smaller chapters to ease navigation, added introductions and system overviews included for most chapters. Edited by Adam Feather, MBBS, FRCP, FAcadMEd; David Randall, MA, MRCP; and Mona Waterhouse, MA, MRCP Contributors comprise consultants at the top of their fields, paired with younger doctors closer to the exam experience, to ensure authority and relevance. Enhanced e-book accompanies the print book, for ease of transportation and use on the move. International Advisory Board, led by Professor Janaka de Silva and Professor Senaka Rajapakse, providing guidance for global coverage from across the world. Contributions to the e-book by members of the International Advisory Board to amplify areas of clinical importance in their parts of the world. Featuring new chapters covering: o Diagnosis: the art of being a doctor – helping readers to develop a confident clinical method in interactions with patients o Geriatric medicine, frailty and multimorbidity o Public health o Surgery o Evidence-based medicine o Sepsis o Haematological Oncology o Venous thromboembolic disease o Hypertension o Men’s health o Obstetric medicine Enhanced clinical skills content has been added to most chapters - helping readers tailor history-taking and examination skills to specific specialty-based contexts.
Book Synopsis Multiple Sclerosis 2 by : W. Ian McDonald
Download or read book Multiple Sclerosis 2 written by W. Ian McDonald and published by Butterworth-Heinemann. This book was released on 2003 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This practical resource encompasses the newest essential information on multiple sclerosis-focusing on those areas where progress has been made in research, bringing about new concepts of patient management"--Back cover.
